2,4-DIBROMOPHENOL (BioDeep_00000406076)

Main id: BioDeep_00000003022

 

natural product


代谢物信息卡片


2,4-DIBROMOPHENOL

化学式: C6H4Br2O (249.8629)
中文名称: 2,4-二溴苯酚
谱图信息: 最多检出来源 not specific(not specific) 0%

分子结构信息

SMILES: BrC1=CC=C(O)C(Br)=C1
InChI: InChI=1S/C6H4Br2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H

描述信息

A bromophenol that is phenol in which the hydrogens at positions 2 and 4 have been replaced by bromines.

同义名列表

2 个代谢物同义名

2,4-DIBROMOPHENOL; 2,4-Dibromophenol



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

11 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 ALB, CASP3, CAT, GZMB, PGR, TBP
Peripheral membrane protein 2 CYP1B1, GBA1
Endoplasmic reticulum membrane 2 CYP1B1, HMOX2
Nucleus 5 ALB, CASP3, GZMB, PGR, TBP
cytosol 6 ALB, CASP3, CAT, GPT, GZMB, PGR
trans-Golgi network 1 GBA1
centrosome 1 ALB
nucleoplasm 5 CASP3, CD2, MNT, PGR, TBP
Cell membrane 1 CD2
Cytoplasmic side 1 HMOX2
Multi-pass membrane protein 1 CACNA1I
cell surface 1 CD2
glutamatergic synapse 1 CASP3
Golgi apparatus 3 ALB, CD2, GBA1
lysosomal membrane 2 GAA, GBA1
neuronal cell body 1 CASP3
Lysosome 2 GAA, GBA1
plasma membrane 5 CACNA1I, CD2, GAA, HMOX2, PGR
Membrane 6 CACNA1I, CAT, CYP1B1, GAA, GZMB, HMOX2
extracellular exosome 5 ALB, CAT, GAA, GBA1, GPT
Lysosome membrane 2 GAA, GBA1
Lumenal side 1 GBA1
endoplasmic reticulum 2 ALB, GBA1
extracellular space 1 ALB
lysosomal lumen 2 GAA, GBA1
mitochondrion 2 CAT, CYP1B1
protein-containing complex 4 ALB, CAT, CD2, TBP
intracellular membrane-bounded organelle 4 CAT, CYP1B1, GAA, GZMB
Microsome membrane 2 CYP1B1, HMOX2
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 CD2
Secreted 3 ALB, GAA, GZMB
extracellular region 5 ALB, CAT, CD2, GAA, GZMB
cytoplasmic side of plasma membrane 1 CD2
mitochondrial outer membrane 1 PGR
mitochondrial matrix 1 CAT
anchoring junction 1 ALB
external side of plasma membrane 1 CD2
cell-cell junction 1 CD2
focal adhesion 1 CAT
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
ciliary basal body 1 ALB
chromatin 3 MNT, PGR, TBP
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
female germ cell nucleus 1 TBP
specific granule membrane 1 HMOX2
tertiary granule membrane 1 GAA
euchromatin 1 TBP
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 1 ALB
male germ cell nucleus 1 TBP
transcription factor TFIID complex 1 TBP
platelet alpha granule lumen 1 ALB
voltage-gated calcium channel complex 1 CACNA1I
azurophil granule membrane 1 GAA
immunological synapse 1 GZMB
Single-pass type IV membrane protein 1 HMOX2
ficolin-1-rich granule membrane 1 GAA
death-inducing signaling complex 1 CASP3
female pronucleus 1 TBP
male pronucleus 1 TBP
catalase complex 1 CAT
[Isoform 4]: Mitochondrion outer membrane 1 PGR
Cytolytic granule 1 GZMB
cytolytic granule lumen 1 GZMB
autolysosome lumen 1 GAA
RNA polymerase transcription factor SL1 complex 1 TBP
transcription factor TFIIA complex 1 TBP
ciliary transition fiber 1 ALB


文献列表

  • Juan Wu, Xindong Yang, Qianwen Wang, Qinghua Zhou, Anping Zhang, Jianqiang Sun. Elucidating the Metabolism of 2,4-Dibromophenol in Plants. Journal of visualized experiments : JoVE. 2023 Feb; ?(192):. doi: 10.3791/65089. [PMID: 36847379]
  • Monika Jarosiewicz, Katarzyna Miłowska, Anita Krokosz, Bożena Bukowska. Evaluation of the Effect of Selected Brominated Flame Retardants on Human Serum Albumin and Human Erythrocyte Membrane Proteins. International journal of molecular sciences. 2020 May; 21(11):. doi: 10.3390/ijms21113926. [PMID: 32486253]
  • Hao Xu, Chao Feng, Yiyi Cao, Ying Lu, Jing Xi, Jieyun Ji, Dasheng Lu, Xin-Yu Zhang, Yang Luan. Distribution of the parent compound and its metabolites in serum, urine, and feces of mice administered 2,2',4,4'-tetrabromodiphenyl ether. Chemosphere. 2019 Jun; 225(?):217-225. doi: 10.1016/j.chemosphere.2019.03.030. [PMID: 30877916]
  • Jianqiang Sun, Qiong Chen, Zhuxiu Qian, Yan Zheng, Shuai Yu, Anping Zhang. Plant Uptake and Metabolism of 2,4-Dibromophenol in Carrot: In Vitro Enzymatic Direct Conjugation. Journal of agricultural and food chemistry. 2018 May; 66(17):4328-4335. doi: 10.1021/acs.jafc.8b00543. [PMID: 29656645]
  • Ka-Lok Ho, Man-Shan Yau, Margaret B Murphy, Yi Wan, Bonnie M-W Fong, Sidney Tam, John P Giesy, Kelvin S-Y Leung, Michael H-W Lam. Urinary bromophenol glucuronide and sulfate conjugates: Potential human exposure molecular markers for polybrominated diphenyl ethers. Chemosphere. 2015 Aug; 133(?):6-12. doi: 10.1016/j.chemosphere.2015.03.003. [PMID: 25817024]
  • María Hijosa-Valsero, Ricardo Molina, Hendrik Schikora, Michael Müller, Josep M Bayona. Removal of priority pollutants from water by means of dielectric barrier discharge atmospheric plasma. Journal of hazardous materials. 2013 Nov; 262(?):664-73. doi: 10.1016/j.jhazmat.2013.09.022. [PMID: 24121639]
  • Anat Bernstein, Zeev Ronen, Elena Levin, Ludwik Halicz, Faina Gelman. Kinetic bromine isotope effect: example from the microbial debromination of brominated phenols. Analytical and bioanalytical chemistry. 2013 Mar; 405(9):2923-9. doi: 10.1007/s00216-012-6446-0. [PMID: 23052885]
  • Feng Xiao, Xiangru Zhang, Hongyan Zhai, Irene M C Lo, George L Tipoe, Mengting Yang, Yang Pan, Guanghao Chen. New halogenated disinfection byproducts in swimming pool water and their permeability across skin. Environmental science & technology. 2012 Jul; 46(13):7112-9. doi: 10.1021/es3010656. [PMID: 22697042]
  • Jessica Norrgran, Bernt Jones, Nils-Gunnar Lindquist, Ake Bergman. Decabromobiphenyl, polybrominated diphenyl ethers, and brominated phenolic compounds in serum of cats diagnosed with the endocrine disease feline hyperthyroidism. Archives of environmental contamination and toxicology. 2012 Jul; 63(1):161-8. doi: 10.1007/s00244-012-9750-y. [PMID: 22311549]
  • Sunil Kumar, Smita Narwal, Vipin Kumar, Om Prakash. α-glucosidase inhibitors from plants: A natural approach to treat diabetes. Pharmacognosy reviews. 2011 Jan; 5(9):19-29. doi: 10.4103/0973-7847.79096. [PMID: 22096315]
  • Won-Jin Sim, Sung-Hee Lee, In-Seok Lee, Sung-Deuk Choi, Jeong-Eun Oh. Distribution and formation of chlorophenols and bromophenols in marine and riverine environments. Chemosphere. 2009 Oct; 77(4):552-8. doi: 10.1016/j.chemosphere.2009.07.006. [PMID: 19664797]
  • Maria Polo, Maria Llompart, Carmen Garcia-Jares, Guadalupe Gomez-Noya, Maria-Herminia Bollain, Rafael Cela. Development of a solid-phase microextraction method for the analysis of phenolic flame retardants in water samples. Journal of chromatography. A. 2006 Aug; 1124(1-2):11-21. doi: 10.1016/j.chroma.2006.03.047. [PMID: 16600262]
  • Zoltán Varga, Attila Bóta, Günter Goerigk. Localization of dibromophenol in DPPC/water liposomes studied by anomalous small-angle X-ray scattering. The journal of physical chemistry. B. 2006 Jun; 110(23):11029-32. doi: 10.1021/jp061750j. [PMID: 16771358]
  • J M Sanders, L-J Chen, E H Lebetkin, L T Burka. Metabolism and disposition of 2,2',4,4'- tetrabromodiphenyl ether following administration of single or multiple doses to rats and mice. Xenobiotica; the fate of foreign compounds in biological systems. 2006 Jan; 36(1):103-17. doi: 10.1080/00498250500485107. [PMID: 16507516]
  • A Puigvert, D Ruano. [Etiopathogenesis of so-called congenital hydronephrosis]. Journal d'urologie et de nephrologie. 1979 Jan; 85(1-2):1-12. doi: NULL. [PMID: 439196]