MOXONIDINE (BioDeep_00000405910)
Main id: BioDeep_00000002540
代谢物信息卡片
MOXONIDINE
化学式: C9H12ClN5O (241.073)
中文名称: 莫索尼定
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=NC(=C(C(=N1)Cl)NC2=NCCN2)OC
InChI: InChI=1S/C9H12ClN5O/c1-5-13-7(10)6(8(14-5)16-2)15-9-11-3-4-12-9/h3-4H2,1-2H3,(H2,11,12,15)
描述信息
C - Cardiovascular system > C02 - Antihypertensives > C02A - Antiadrenergic agents, centrally acting > C02AC - Imidazoline receptor agonists
C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
同义名列表
2 个代谢物同义名
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:7009
- KEGG: C07451
- KEGGdrug: D05087
- PubChem: 4810
- DrugBank: DB09242
- ChEMBL: CHEMBL19236
- CAS: 1008754-16-2
- CAS: 75438-57-2
- MoNA: FiehnHILIC002114
- MoNA: FiehnHILIC000541
- PubChem: 9654
- NIKKAJI: J32.886C
- RefMet: Moxonidine
- KNApSAcK: 7009
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yutang Wang, Dinh Tam Nguyen, Jack Anesi, Ahmed Alramahi, Paul K Witting, Zhonglin Chai, Abdul Waheed Khan, Jason Kelly, Kate M Denton, Jonathan Golledge. Moxonidine Increases Uptake of Oxidised Low-Density Lipoprotein in Cultured Vascular Smooth Muscle Cells and Inhibits Atherosclerosis in Apolipoprotein E-Deficient Mice.
International journal of molecular sciences.
2023 Feb; 24(4):. doi:
10.3390/ijms24043857. [PMID: 36835270] - Shaimaa S El-Sayed, Samar Rezq, Amira Ebrahim Alsemeh, Mona F Mahmoud. Moxonidine ameliorates cardiac injury in rats with metabolic syndrome by regulating autophagy.
Life sciences.
2023 Jan; 312(?):121210. doi:
10.1016/j.lfs.2022.121210. [PMID: 36410408] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
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BMC pharmacology.
2005 Mar; 5(?):4. doi:
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Kidney international. Supplement.
2005 Jan; ?(93):S20-4. doi:
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Journal of clinical hypertension (Greenwich, Conn.).
2004 Dec; 6(12):682-9. doi:
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Journal of the American Society of Nephrology : JASN.
2004 Nov; 15(11):2902-7. doi:
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Journal of human hypertension.
2004 Sep; 18(9):669-75. doi:
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Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2004 Sep; 19(9):2217-22. doi:
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Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
2004 Aug; 37(8):1239-45. doi:
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American journal of physiology. Heart and circulatory physiology.
2004 Jul; 287(1):H150-6. doi:
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Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.
2004 Jun; 112(6):315-22. doi:
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Journal of cardiovascular pharmacology.
2004 May; 43(5):731-6. doi:
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British journal of clinical pharmacology.
2004 May; 57(5):545-51. doi:
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International journal of clinical practice.
2004 May; 58(5):465-8. doi:
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International journal of clinical practice. Supplement.
2004 Mar; ?(139):26-32. doi:
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Kardiologiia.
2004; 44(9):13-5. doi:
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Terapevticheskii arkhiv.
2004; 76(12):27-32. doi:
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Annals of the New York Academy of Sciences.
2003 Dec; 1009(?):75-81. doi:
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Annals of the New York Academy of Sciences.
2003 Dec; 1009(?):244-50. doi:
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The Journal of pharmacology and experimental therapeutics.
2003 Dec; 307(3):1104-11. doi:
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Annals of the New York Academy of Sciences.
2003 Dec; 1009(?):251-61. doi:
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Annals of the New York Academy of Sciences.
2003 Dec; 1009(?):288-95. doi:
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European journal of heart failure.
2003 Oct; 5(5):659-67. doi:
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Journal of hypertension.
2003 Sep; 21(9):1709-17. doi:
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Journal of medicinal chemistry.
2003 May; 46(10):1962-79. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2003 Mar; 31(3):334-42. doi:
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Kardiologiia.
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Circulation.
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Pflugers Archiv : European journal of physiology.
2002 Oct; 445(1):32-9. doi:
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Journal of biochemical and biophysical methods.
2002 Oct; 53(1-3):131-9. doi:
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American journal of hypertension.
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British journal of clinical pharmacology.
2002 Sep; 54(3):251-4. doi:
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The international journal of neuropsychopharmacology.
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Clinical physiology and functional imaging.
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