Icarin (BioDeep_00000405861)
代谢物信息卡片
化学式: C33H40O15 (676.236709)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1C(C(C(C(O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)OC4C(C(C(C(O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O
InChI: InChI=1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
10 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Peng Yu, Zhen Qian, Hongmei Yang, Tianyang Xu, Yulin Dai, Laihui Song, Jinling Liang, Yuying Shi, Zhiguo Zhang, Lijing Li. Icaritin, a metabolite of Icarrin, Alleviates non-alcoholic fatty liver disease via inhibition of lipogenesis and ER stress.
European journal of pharmacology.
2022 Dec; 937(?):175378. doi:
10.1016/j.ejphar.2022.175378. [PMID: 36372277] - Zhiqiang Qian, Ling Zhu, Yeli Li, Yiqi Li, Yuting Wu, Shu Fu, Danli Yang. Icarrin prevents cardiomyocyte apoptosis in spontaneously hypertensive rats by inhibiting endoplasmic reticulum stress pathways.
The Journal of pharmacy and pharmacology.
2021 Jul; 73(8):1023-1032. doi:
10.1093/jpp/rgaa016. [PMID: 34018553] - Qisheng Feng, Lin Tong, Huiwen Guo, Chang Ma, Feng Qin, Zhili Xiong. Tailor-made deep eutectic solvents extraction combined with UPLC-MS/MS determination of icarrin and icarisid II in rat plasma and its comparative pharmacokinetic application.
Journal of pharmaceutical and biomedical analysis.
2021 May; 199(?):114054. doi:
10.1016/j.jpba.2021.114054. [PMID: 33831735] - Lei Ye, Yaping Yu, Yanping Zhao. Icariin-induced miR-875-5p attenuates epithelial-mesenchymal transition by targeting hedgehog signaling in liver fibrosis.
Journal of gastroenterology and hepatology.
2020 Mar; 35(3):482-491. doi:
10.1111/jgh.14875. [PMID: 31617598] - Si Sun, Le Liu, Xiaojun Tian, Yanghongyun Guo, Yingkang Cao, Yunqing Mei, Changhua Wang. Icariin Attenuates High Glucose-Induced Apoptosis, Oxidative Stress, and Inflammation in Human Umbilical Venous Endothelial Cells.
Planta medica.
2019 Apr; 85(6):473-482. doi:
10.1055/a-0837-0975. [PMID: 30703815] - Mi Huang, Jing Feng, Zai-Xuan Zhong, Shun-Ping He, Yu-Qin Shu, Jiang-Yan He, Ying Wang. [Activity Study of Icarlin and Epimedin C Monomer under the Same Molarity in Osteoporosis Ze- brafish Model].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2016 08; 36(8):986-990. doi:
. [PMID: 30640996] - Yan-Qiu Liu, Xiao-Fei Han, Tiegang Liu, Meng-Chun Cheng, Hong-Bin Xiao. A cell-based model of bone remodeling for identifying activity of icarrin in the treatment of osteoporosis.
Biotechnology letters.
2015 Jan; 37(1):219-26. doi:
10.1007/s10529-014-1661-8. [PMID: 25257584]