Hydroxypropionic acid (BioDeep_00000405340)
Main id: BioDeep_00000003204
PANOMIX_OTCML-2023
代谢物信息卡片
3-Hydroxypropionic acid
化学式: C3H6O3 (90.0317)
中文名称: 3-羟基丙酸(含有数量不等的3,3-氧基二丙酸), 3-羟基丙酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(CO)C(=O)O
InChI: InChI=1S/C3H6O3/c4-2-1-3(5)6/h4H,1-2H2,(H,5,6)
描述信息
A 3-hydroxy monocarboxylic acid that is propionic acid in which one of the hydrogens attached to the terminal carbon is replaced by a hydroxy group.
Hydroxypropionic acid, also known as 3-hydroxypropionate or hydracrylic acid, belongs to beta hydroxy acids and derivatives class of compounds. Those are compounds containing a carboxylic acid substituted with a hydroxyl group on the C3 carbon atom. Hydroxypropionic acid is soluble (in water) and a weakly acidic compound (based on its pKa). Hydroxypropionic acid can be synthesized from propionic acid. Hydroxypropionic acid is also a parent compound for other transformation products, including but not limited to, beta-propiolactone, ascr#5, and 3-hydroxypropanoyl-CoA. Hydroxypropionic acid can be found in a number of food items such as apple, poppy, yam, and cupuaçu, which makes hydroxypropionic acid a potential biomarker for the consumption of these food products. Hydroxypropionic acid can be found primarily in blood, cerebrospinal fluid (CSF), feces, and urine. Hydroxypropionic acid exists in all living organisms, ranging from bacteria to humans. In humans, hydroxypropionic acid is involved in the propanoate metabolism. Hydroxypropionic acid is also involved in few metabolic disorders, which include malonic aciduria, malonyl-coa decarboxylase deficiency, and methylmalonic aciduria due to cobalamin-related disorders. Moreover, hydroxypropionic acid is found to be associated with biotinidase deficiency and propionic acidemia. Hydroxypropionic acid is a non-carcinogenic (not listed by IARC) potentially toxic compound. Hydroxypropanoic acid, or alternately hydroxypropionic acid, may refer to either of two isomeric chemical compounds: 3-Hydroxypropionic acid (hydracrylic acid) Lactic acid (2-hydroxypropanoic acid) . Chronically high levels of hydroxypropionic acid are associated with at least 5 inborn errors of metabolism including: Biotinidase deficiency, Malonic Aciduria, Methylmalonate Semialdehyde Dehydrogenase Deficiency, Methylmalonic Aciduria, Methylmalonic, Aciduria Due to Cobalamin-Related Disorders and Propionic acidemia (T3DB).
同义名列表
数据库引用编号
18 个数据库交叉引用编号
- ChEBI: CHEBI:33404
- KEGG: C01013
- PubChem: 68152
- DrugBank: DB03688
- ChEMBL: CHEMBL1205969
- foodb: FDB030432
- CAS: 503-66-2
- MoNA: HMDB0000700_ms_ms_975
- MoNA: HMDB0000700_ms_ms_976
- MoNA: HMDB0000700_ms_ms_977
- MetaboLights: MTBLC33404
- ChEBI: CHEBI:16510
- PubChem: 4258
- PDB-CCD: 3OH
- 3DMET: B00221
- NIKKAJI: J6.213H
- RefMet: Hydroxypropionic acid
- KNApSAcK: 16510
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
8 个相关的物种来源信息
- 1080010 - Aloe africana: 10.1021/JF071110T
- 3702 - Arabidopsis thaliana: 10.1073/PNAS.1403248111
- 7227 - Drosophila melanogaster: 10.1038/S41467-019-11933-Z
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
- 3879 - Medicago sativa: 10.3389/FPLS.2017.01208
- 1807034 - Phomopsis phaseoli: 10.1016/J.PHYTOCHEM.2004.06.035
- 28511 - Pogostemon cablin: 10.1021/JF304466T
- 28901 - Salmonella enterica: 10.1021/ACS.JPROTEOME.0C00281
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Nailing Qi, Wentao Ding, Genlai Dong, Zhihui Wang, Shuobo Shi. De novo bio-production of odd-chain fatty acids in Saccharomyces cerevisiae through a synthetic pathway via 3-hydroxypropionic acid.
Biotechnology and bioengineering.
2023 03; 120(3):852-858. doi:
10.1002/bit.28297. [PMID: 36464776] - Juefeng Lu, Yuying Wang, Mingcheng Xu, Qiang Fei, Yang Gu, Yuanchan Luo, Hui Wu. Efficient biosynthesis of 3-hydroxypropionic acid from ethanol in metabolically engineered Escherichia coli.
Bioresource technology.
2022 Nov; 363(?):127907. doi:
10.1016/j.biortech.2022.127907. [PMID: 36087655] - Shengfang Zhou, Suman Lama, Jihong Jiang, Mugesh Sankaranarayanan, Sunghoon Park. Use of acetate for the production of 3-hydroxypropionic acid by metabolically-engineered Pseudomonas denitrificans.
Bioresource technology.
2020 Jul; 307(?):123194. doi:
10.1016/j.biortech.2020.123194. [PMID: 32234590] - Ying Xu, Zhe Zhao, Wenhua Tong, Yamei Ding, Bin Liu, Yixin Shi, Jichao Wang, Shenmei Sun, Min Liu, Yuhui Wang, Qingsheng Qi, Mo Xian, Guang Zhao. An acid-tolerance response system protecting exponentially growing Escherichia coli.
Nature communications.
2020 03; 11(1):1496. doi:
10.1038/s41467-020-15350-5. [PMID: 32198415] - Nam Hoai Nguyen, Satish Kumar Ainala, Shengfang Zhou, Sunghoon Park. A novel 3-hydroxypropionic acid-inducible promoter regulated by the LysR-type transcriptional activator protein MmsR of Pseudomonas denitrificans.
Scientific reports.
2019 03; 9(1):5333. doi:
10.1038/s41598-019-41785-y. [PMID: 30926872] - Lakshmi Venkata Naga Satya Khandavalli, Tushar Lodha, Maaged Abdullah, Lalitha Guruprasad, Sasikala Chintalapati, Venkata Ramana Chintalapati. Insights into the carbonic anhydrases and autotrophic carbon dioxide fixation pathways of high CO2 tolerant Rhodovulum viride JA756.
Microbiological research.
2018 Oct; 215(?):130-140. doi:
10.1016/j.micres.2018.07.006. [PMID: 30172299] - Hafsa Majid, Lena Jafri, Aysha Habib Khan, Zeba Zulfiqar Ali, Azeema Jamil, Nasir Yusufzai, Midhat Fatimah, Bushra Afroze. Diagnostic dilemma of patients with methylmalonic aciduria: Experience from a tertiary care centre in Pakistan.
JPMA. The Journal of the Pakistan Medical Association.
2018 Apr; 68(4):510-514. doi:
NULL. [PMID: 29808036] - Nicola Longo, Leisa B Price, Eduard Gappmaier, Nancy L Cantor, Sharon L Ernst, Carrie Bailey, Marzia Pasquali. Anaplerotic therapy in propionic acidemia.
Molecular genetics and metabolism.
2017 09; 122(1-2):51-59. doi:
10.1016/j.ymgme.2017.07.003. [PMID: 28712602] - Albin Alfreider, Andreas Baumer, Teresa Bogensperger, Thomas Posch, Michaela M Salcher, Monika Summerer. CO2 assimilation strategies in stratified lakes: Diversity and distribution patterns of chemolithoautotrophs.
Environmental microbiology.
2017 07; 19(7):2754-2768. doi:
10.1111/1462-2920.13786. [PMID: 28474482] - Jana Konkoľová, Ján Chandoga, Juraj Kováčik, Marcel Repiský, Veronika Kramarová, Ivana Paučinová, Daniel Böhmer. Severe child form of primary hyperoxaluria type 2 - a case report revealing consequence of GRHPR deficiency on metabolism.
BMC medical genetics.
2017 05; 18(1):59. doi:
10.1186/s12881-017-0421-8. [PMID: 28569194] - Laura A Hug, Brian C Thomas, Itai Sharon, Christopher T Brown, Ritin Sharma, Robert L Hettich, Michael J Wilkins, Kenneth H Williams, Andrea Singh, Jillian F Banfield. Critical biogeochemical functions in the subsurface are associated with bacteria from new phyla and little studied lineages.
Environmental microbiology.
2016 Jan; 18(1):159-73. doi:
10.1111/1462-2920.12930. [PMID: 26033198] - Masroor Qadri, Ramesh Deshidi, Bhawal Ali Shah, Kushal Bindu, Ram A Vishwakarma, Syed Riyaz-Ul-Hassan. An endophyte of Picrorhiza kurroa Royle ex. Benth, producing menthol, phenylethyl alcohol and 3-hydroxypropionic acid, and other volatile organic compounds.
World journal of microbiology & biotechnology.
2015 Oct; 31(10):1647-54. doi:
10.1007/s11274-015-1910-6. [PMID: 26220851] - Yeounjoo Ko, Somasundar Ashok, Satish Kumar Ainala, Mugesh Sankaranarayanan, Ah Yeong Chun, Gyoo Yeol Jung, Sunghoon Park. Coenzyme B12 can be produced by engineered Escherichia coli under both anaerobic and aerobic conditions.
Biotechnology journal.
2014 Dec; 9(12):1526-35. doi:
10.1002/biot.201400221. [PMID: 25146562] - Mitsuharu Matsumoto, Toshiya Ebata, Junko Hirooka, Ritsuko Hosoya, Natsuhiko Inoue, Satomi Itami, Kazuo Tsuji, Taketoshi Yaginuma, Koji Muramatsu, Atsuo Nakamura, Ayako Fujita, Toshikazu Nagakura. Antipruritic effects of the probiotic strain LKM512 in adults with atopic dermatitis.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
2014 Aug; 113(2):209-216.e7. doi:
10.1016/j.anai.2014.05.002. [PMID: 24893766] - Mathilde Nizon, Chris Ottolenghi, Vassili Valayannopoulos, Jean-Baptiste Arnoux, Valérie Barbier, Florence Habarou, Isabelle Desguerre, Nathalie Boddaert, Jean-Paul Bonnefont, Cécile Acquaviva, Jean-François Benoist, Daniel Rabier, Guy Touati, Pascale de Lonlay. Long-term neurological outcome of a cohort of 80 patients with classical organic acidurias.
Orphanet journal of rare diseases.
2013 Sep; 8(?):148. doi:
10.1186/1750-1172-8-148. [PMID: 24059531] - Matthew W Keller, Gerrit J Schut, Gina L Lipscomb, Angeli L Menon, Ifeyinwa J Iwuchukwu, Therese T Leuko, Michael P Thorgersen, William J Nixon, Aaron S Hawkins, Robert M Kelly, Michael W W Adams. Exploiting microbial hyperthermophilicity to produce an industrial chemical, using hydrogen and carbon dioxide.
Proceedings of the National Academy of Sciences of the United States of America.
2013 Apr; 110(15):5840-5. doi:
10.1073/pnas.1222607110. [PMID: 23530213] - Nanqiu Peng, Yi Zhong, Qing Zhang, Mingyue Zheng, Wei Zhao, Hualiang Jiang, Chen Yang, Xiaokui Guo, Guoping Zhao. Characterization of acetyl-CoA and propionyl-CoA carboxylases encoded by Leptospira interrogans serovar Lai: an initial biochemical study for leptospiral gluconeogenesis via anaplerotic CO(2) assimilation.
Acta biochimica et biophysica Sinica.
2012 Aug; 44(8):692-702. doi:
10.1093/abbs/gms047. [PMID: 22710261] - Atsuki Ikeda, Shin Nishiumi, Masakazu Shinohara, Tomoo Yoshie, Naoya Hatano, Tatsuya Okuno, Takeshi Bamba, Eiichiro Fukusaki, Tadaomi Takenawa, Takeshi Azuma, Masaru Yoshida. Serum metabolomics as a novel diagnostic approach for gastrointestinal cancer.
Biomedical chromatography : BMC.
2012 May; 26(5):548-58. doi:
10.1002/bmc.1671. [PMID: 21773981] - Meixia Huang, Wensheng Pang, Jing Zhang, Siding Lin, Juan Hu. A target analogue imprinted polymer for the recognition of antiplatelet active ingredients in Radix Salviae Miltiorrhizae by LC/MS/MS.
Journal of pharmaceutical and biomedical analysis.
2012 Jan; 58(?):12-8. doi:
10.1016/j.jpba.2011.09.010. [PMID: 21978827] - William R Lagor, David W Fields, Sumeet A Khetarpal, Arthi Kumaravel, Wen Lin, Nathaniel Weintraub, Kaijin Wu, Sarah F Hamm-Alvarez, Denise Drazul-Schrader, Margarita de la Llera-Moya, George H Rothblat, Daniel J Rader. The effects of apolipoprotein F deficiency on high density lipoprotein cholesterol metabolism in mice.
PloS one.
2012; 7(2):e31616. doi:
10.1371/journal.pone.0031616. [PMID: 22363685] - Rubem R Amador, João Paulo Figueiró Longo, Zulmira G Lacava, José G Dórea, Maria de Fátima M Almeida Santos. Metformin (dimethyl-biguanide) induced DNA damage in mammalian cells.
Genetics and molecular biology.
2012 Jan; 35(1):153-8. doi:
10.1590/s1415-47572011005000060. [PMID: 22481889] - M P Almeida, C P Rezende, L F Souza, R B Brito. Validation of a quantitative and confirmatory method for residue analysis of aminoglycoside antibiotics in poultry, bovine, equine and swine kidney through liquid chromatography-tandem mass spectrometry.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2012; 29(4):517-25. doi:
10.1080/19440049.2011.623681. [PMID: 22059623] - Jaciana S Aguiar, Rosilma O Araújo, Maria Do Desterro Rodrigues, Kêsia X F R Sena, André M Batista, Maria M P Guerra, Steno L Oliveira, Josean F Tavares, Marcelo S Silva, Silene C Nascimento, Teresinha Gonçalves Da Silva. Antimicrobial, antiproliferative and proapoptotic activities of extract, fractions and isolated compounds from the stem of Erythroxylum caatingae plowman.
International journal of molecular sciences.
2012; 13(4):4124-4140. doi:
10.3390/ijms13044124. [PMID: 22605969] - Maren Müller, Sergi Munné-Bosch. Rapid and sensitive hormonal profiling of complex plant samples by liquid chromatography coupled to electrospray ionization tandem mass spectrometry.
Plant methods.
2011 Nov; 7(?):37. doi:
10.1186/1746-4811-7-37. [PMID: 22098763] - Natalia Borowska, Dominika Idziak, Robert Hasterok. DNA methylation patterns of Brachypodium distachyon chromosomes and their alteration by 5-azacytidine treatment.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology.
2011 Nov; 19(8):955-67. doi:
10.1007/s10577-011-9243-2. [PMID: 22076608] - Dominika Idziak, Alexander Betekhtin, Elzbieta Wolny, Karolina Lesniewska, Jonathan Wright, Melanie Febrer, Michael W Bevan, Glyn Jenkins, Robert Hasterok. Painting the chromosomes of Brachypodium: current status and future prospects.
Chromosoma.
2011 Oct; 120(5):469-79. doi:
10.1007/s00412-011-0326-9. [PMID: 21667205] - Giuliana Giannuzzi, Pietro D'Addabbo, Marica Gasparro, Maurizio Martinelli, Francesco N Carelli, Donato Antonacci, Mario Ventura. Analysis of high-identity segmental duplications in the grapevine genome.
BMC genomics.
2011 Aug; 12(?):436. doi:
10.1186/1471-2164-12-436. [PMID: 21871077] - J S P Yuen, M Y Sim, H G Siml, T W Chong, W K O Lau, C W S Cheng, H Huynh. Inhibition of angiogenic and non-angiogenic targets by sorafenib in renal cell carcinoma (RCC) in a RCC xenograft model.
British journal of cancer.
2011 Mar; 104(6):941-7. doi:
10.1038/bjc.2011.55. [PMID: 21407223] - Yonghua Han, Zhonghua Zhang, Sanwen Huang, Weiwei Jin. An integrated molecular cytogenetic map of Cucumis sativus L. chromosome 2.
BMC genetics.
2011 Jan; 12(?):18. doi:
10.1186/1471-2156-12-18. [PMID: 21272311] - Jan Huege, Jan Goetze, Doreen Schwarz, Hermann Bauwe, Martin Hagemann, Joachim Kopka. Modulation of the major paths of carbon in photorespiratory mutants of synechocystis.
PloS one.
2011 Jan; 6(1):e16278. doi:
10.1371/journal.pone.0016278. [PMID: 21283704] - Steffen U Eisenhardt, Jonathon Habersberger, Karen Oliva, Graeme I Lancaster, Mustafa Ayhan, Kevin J Woollard, Holger Bannasch, Greg E Rice, Karlheinz Peter. A proteomic analysis of C-reactive protein stimulated THP-1 monocytes.
Proteome science.
2011 Jan; 9(1):1. doi:
10.1186/1477-5956-9-1. [PMID: 21219634] - Yang Li, Ming Cang, Andrew Stephen Lee, Kehua Zhang, Dongjun Liu. Reprogramming of sheep fibroblasts into pluripotency under a drug-inducible expression of mouse-derived defined factors.
PloS one.
2011 Jan; 6(1):e15947. doi:
10.1371/journal.pone.0015947. [PMID: 21253598] - Yuhai Zhao, Frederic Calon, Carl Julien, Jeremy W Winkler, Nicos A Petasis, Walter J Lukiw, Nicolas G Bazan. Docosahexaenoic acid-derived neuroprotectin D1 induces neuronal survival via secretase- and PPARγ-mediated mechanisms in Alzheimer's disease models.
PloS one.
2011 Jan; 6(1):e15816. doi:
10.1371/journal.pone.0015816. [PMID: 21246057] - Gen-Ichiro Arimura, Rika Ozawa, Massimo E Maffei. Recent advances in plant early signaling in response to herbivory.
International journal of molecular sciences.
2011; 12(6):3723-39. doi:
10.3390/ijms12063723. [PMID: 21747702] - Yosuke Shigematsu, Ikue Hata, Go Tajima. Useful second-tier tests in expanded newborn screening of isovaleric acidemia and methylmalonic aciduria.
Journal of inherited metabolic disease.
2010 Oct; 33(Suppl 2):S283-8. doi:
10.1007/s10545-010-9111-9. [PMID: 20440648] - Alejandra Hernández-Ceruelos, Eduardo Madrigal-Santillán, José Antonio Morales-González, Germán Chamorro-Cevallos, Martha Cassani-Galindo, Eduardo Madrigal-Bujaidar. Antigenotoxic effect of Chamomilla recutita (L.) Rauschert essential oil in mouse spermatogonial cells, and determination of its antioxidant capacity in vitro.
International journal of molecular sciences.
2010 Sep; 11(10):3793-802. doi:
10.3390/ijms11103793. [PMID: 21152302] - Nathalie Wuyts, Jean-Christophe Palauqui, Geneviève Conejero, Jean-Luc Verdeil, Christine Granier, Catherine Massonnet. High-contrast three-dimensional imaging of the Arabidopsis leaf enables the analysis of cell dimensions in the epidermis and mesophyll.
Plant methods.
2010 Jul; 6(?):17. doi:
10.1186/1746-4811-6-17. [PMID: 20598116] - C Chebbah, O J Pozo, K Deventer, P Van Eenoo, F T Delbeke. Direct quantification of 11-nor-Delta(9)-tetrahydrocannabinol-9-carboxylic acid in urine by liquid chromatography/tandem mass spectrometry in relation to doping control analysis.
Rapid communications in mass spectrometry : RCM.
2010 Apr; 24(8):1133-41. doi:
10.1002/rcm.4499. [PMID: 20301101] - Raffaella Melzi, Barbara Antonioli, Alessia Mercalli, Manuela Battaglia, Andrea Valle, Stefano Pluchino, Rossella Galli, Valeria Sordi, Emanuele Bosi, Gianvito Martino, Ezio Bonifacio, Claudio Doglioni, Lorenzo Piemonti. Co-graft of allogeneic immune regulatory neural stem cells (NPC) and pancreatic islets mediates tolerance, while inducing NPC-derived tumors in mice.
PloS one.
2010 Apr; 5(4):e10357. doi:
10.1371/journal.pone.0010357. [PMID: 20436918] - Angel Gu, Zhifang Zhang, Nan Zhang, Walter Tsark, John E Shively. Generation of human CEACAM1 transgenic mice and binding of Neisseria Opa protein to their neutrophils.
PloS one.
2010 Apr; 5(4):e10067. doi:
10.1371/journal.pone.0010067. [PMID: 20404914] - Aidan D Meade, Colin Clarke, Florence Draux, Ganesh D Sockalingum, Michel Manfait, Fiona M Lyng, Hugh J Byrne. Studies of chemical fixation effects in human cell lines using Raman microspectroscopy.
Analytical and bioanalytical chemistry.
2010 Mar; 396(5):1781-91. doi:
10.1007/s00216-009-3411-7. [PMID: 20087730] - Naoki Takahashi, Mauricio Quimbaya, Veit Schubert, Tim Lammens, Klaas Vandepoele, Ingo Schubert, Minami Matsui, Dirk Inzé, Geert Berx, Lieven De Veylder. The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair.
PLoS genetics.
2010 Jan; 6(1):e1000817. doi:
10.1371/journal.pgen.1000817. [PMID: 20090939] - Ishita S Mehta, Manelle Amira, Amanda J Harvey, Joanna M Bridger. Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts.
Genome biology.
2010 Jan; 11(1):R5. doi:
10.1186/gb-2010-11-1-r5. [PMID: 20070886] - Laura R Jarboe, Xueli Zhang, Xuan Wang, Jonathan C Moore, K T Shanmugam, Lonnie O Ingram. Metabolic engineering for production of biorenewable fuels and chemicals: contributions of synthetic biology.
Journal of biomedicine & biotechnology.
2010; 2010(?):761042. doi:
10.1155/2010/761042. [PMID: 20414363] - Simon R Ellwood, Zhaohui Liu, Rob A Syme, Zhibing Lai, James K Hane, Felicity Keiper, Caroline S Moffat, Richard P Oliver, Timothy L Friesen. A first genome assembly of the barley fungal pathogen Pyrenophora teres f. teres.
Genome biology.
2010; 11(11):R109. doi:
10.1186/gb-2010-11-11-r109. [PMID: 21067574] - J Ye, T Wang, L S Han, W J Qiu, H W Zhang, Y F Zhang, X L Gao, Y Wang, X F Gu. Diagnosis, treatment, follow-up and gene mutation analysis in four Chinese children with biotinidase deficiency.
Journal of inherited metabolic disease.
2009 Dec; 32 Suppl 1(?):S295-302. doi:
10.1007/s10545-009-1238-1. [PMID: 19728141] - Mehran Javanbakht, Mohammad Hadi Namjumanesh, Behrouz Akbari-Adergani. Molecularly imprinted solid-phase extraction for the selective determination of bromhexine in human serum and urine with high performance liquid chromatography.
Talanta.
2009 Nov; 80(1):133-8. doi:
10.1016/j.talanta.2009.06.033. [PMID: 19782202] - Gallen B Triana-Baltzer, Larisa V Gubareva, John M Nicholls, Melissa B Pearce, Vasiliy P Mishin, Jessica A Belser, Li-Mei Chen, Renee W Y Chan, Michael C W Chan, Maria Hedlund, Jeffrey L Larson, Ronald B Moss, Jacqueline M Katz, Terrence M Tumpey, Fang Fang. Novel pandemic influenza A(H1N1) viruses are potently inhibited by DAS181, a sialidase fusion protein.
PloS one.
2009 Nov; 4(11):e7788. doi:
10.1371/journal.pone.0007788. [PMID: 19893747] - Bhupendra Chaudhary, Ran Hovav, Lex Flagel, Ron Mittler, Jonathan F Wendel. Parallel expression evolution of oxidative stress-related genes in fiber from wild and domesticated diploid and polyploid cotton (Gossypium).
BMC genomics.
2009 Aug; 10(?):378. doi:
10.1186/1471-2164-10-378. [PMID: 19686594] - Mehran Javanbakht, Narges Shaabani, Behrouz Akbari-Adergani. Novel molecularly imprinted polymers for the selective extraction and determination of metoclopramide in human serum and urine samples using high-performance liquid chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2009 Aug; 877(24):2537-44. doi:
10.1016/j.jchromb.2009.06.030. [PMID: 19604730] - Astrid Rohrbeck, Volker Steffen Müller, Jürgen Borlak. Molecular characterization of lung dysplasia induced by c-Raf-1.
PloS one.
2009 May; 4(5):e5637. doi:
10.1371/journal.pone.0005637. [PMID: 19529782] - Dása Umysová, Milada Vítová, Irena Dousková, Katerina Bisová, Monika Hlavová, Mária Cízková, Jirí Machát, Jirí Doucha, Vilém Zachleder. Bioaccumulation and toxicity of selenium compounds in the green alga Scenedesmus quadricauda.
BMC plant biology.
2009 May; 9(?):58. doi:
10.1186/1471-2229-9-58. [PMID: 19445666] - Jennifer A Johnson, Kenneth L Le, Enrique Palacios. Propionic acidemia: case report and review of neurologic sequelae.
Pediatric neurology.
2009 Apr; 40(4):317-20. doi:
10.1016/j.pediatrneurol.2008.10.021. [PMID: 19302949] - Minglei Tian, Hongyuan Yan, Kyung Ho Row. Solid-phase extraction of tanshinones from Salvia Miltiorrhiza Bunge using ionic liquid-modified silica sorbents.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2009 Mar; 877(8-9):738-42. doi:
10.1016/j.jchromb.2009.02.012. [PMID: 19237325] - Seongwon Seo, Harris A Lewin. Reconstruction of metabolic pathways for the cattle genome.
BMC systems biology.
2009 Mar; 3(?):33. doi:
10.1186/1752-0509-3-33. [PMID: 19284618] - Lingzhi Bao, An Xu, Liping Tong, Shaopeng Chen, Lingyan Zhu, Ye Zhao, Guoping Zhao, Erkang Jiang, Jun Wang, Lijun Wu. Activated toxicity of diesel particulate extract by ultraviolet a radiation in mammalian cells: role of singlet oxygen.
Environmental health perspectives.
2009 Mar; 117(3):436-41. doi:
10.1289/ehp.0800029. [PMID: 19337519] - Annamaria Buschini, Lisa Ferrarini, Susanna Franzoni, Serena Galati, Mirca Lazzaretti, Francesca Mussi, Cristina Northfleet de Albuquerque, Tânia Maria Araújo Domingues Zucchi, Paola Poli. Genotoxicity revaluation of three commercial nitroheterocyclic drugs: nifurtimox, benznidazole, and metronidazole.
Journal of parasitology research.
2009; 2009(?):463575. doi:
10.1155/2009/463575. [PMID: 20981287] - Yuk-Kien Chong, Tan-Boon Toh, Norazean Zaiden, Anuradha Poonepalli, Siew Hong Leong, Catherine Ee Ling Ong, Yiting Yu, Patrick B Tan, Siew-Ju See, Wai-Hoe Ng, Ivan Ng, Manoor P Hande, Oi Lian Kon, Beng-Ti Ang, Carol Tang. Cryopreservation of neurospheres derived from human glioblastoma multiforme.
Stem cells (Dayton, Ohio).
2009 Jan; 27(1):29-39. doi:
10.1634/stemcells.2008-0009. [PMID: 18845764] - Tatsuya Higashi, Hiroyuki Yokoi, Yukiko Nagura, Tadashi Nishio, Kazutake Shimada. Studies on neurosteroids XXIV. Determination of neuroactive androgens, androsterone and 5alpha-androstane-3alpha,17beta-diol, in rat brain and serum using liquid chromatography-tandem mass spectrometry.
Biomedical chromatography : BMC.
2008 Dec; 22(12):1434-41. doi:
10.1002/bmc.1078. [PMID: 18655222] - Ashutosh Halder, Manish Jain, Madhulika Kabra, Neerja Gupta. Mosaic 22q11.2 microdeletion syndrome: diagnosis and clinical manifestations of two cases.
Molecular cytogenetics.
2008 Aug; 1(?):18. doi:
10.1186/1755-8166-1-18. [PMID: 18691436] - Tatsuya Higashi, Yasuaki Ninomiya, Kazutake Shimada. Studies on neurosteroids XX. Liquid chromatography-tandem mass spectrometric method for simultaneous determination of testosterone and 5alpha-dihydrotestosterone in rat brain and serum.
Journal of chromatographic science.
2008 Aug; 46(7):653-8. doi:
10.1093/chromsci/46.7.653. [PMID: 18718144] - Hidetoshi Morita, Hidehiro Toh, Shinji Fukuda, Hiroshi Horikawa, Kenshiro Oshima, Takehito Suzuki, Masaru Murakami, Shin Hisamatsu, Yukio Kato, Tatsuya Takizawa, Hideo Fukuoka, Tetsuhiko Yoshimura, Kikuji Itoh, Daniel J O'Sullivan, Larry L McKay, Hiroshi Ohno, Jun Kikuchi, Toshio Masaoka, Masahira Hattori. Comparative genome analysis of Lactobacillus reuteri and Lactobacillus fermentum reveal a genomic island for reuterin and cobalamin production.
DNA research : an international journal for rapid publication of reports on genes and genomes.
2008 Jun; 15(3):151-61. doi:
10.1093/dnares/dsn009. [PMID: 18487258] - F Samartzi, I Tsakmakidis, E Theodosiadou, E Vainas. Effect of porcine and ovine FSH on nuclear maturation of pig oocytes in vitro.
Reproduction in domestic animals = Zuchthygiene.
2008 Apr; 43(2):153-6. doi:
10.1111/j.1439-0531.2007.00868.x. [PMID: 18325004] - J R Aarestrup, D Karam, G W Fernandes. Chromosome number and cytogenetics of Euphorbia heterophylla L.
Genetics and molecular research : GMR.
2008 Mar; 7(1):217-22. doi:
10.4238/vol7-1gmr421. [PMID: 18393225] - Yao Zhang, Yan-ling Yang, Yuki Hasegawa, Seiji Yamaguchi, Chun-yan Shi, Jin-qing Song, Sujan Sayami, Ping Liu, Rong Yan, Jin-hua Dong, Jiong Qin. Prenatal diagnosis of methylmalonic aciduria by analysis of organic acids and total homocysteine in amniotic fluid.
Chinese medical journal.
2008 Feb; 121(3):216-9. doi:
. [PMID: 18298912] - Sunil K Chattopadhyay, Satyanshu Kumar. Liquid chromatography-tandem mass spectrometry method for identification and quantification of two biologically active polyisoprenylated benzophenones, isoxanthochymol and camboginol, in Garcinia species.
Biomedical chromatography : BMC.
2007 Nov; 21(11):1159-65. doi:
10.1002/bmc.868. [PMID: 17583544] - Kerry A Lucas, Jessica R Filley, Jeremy M Erb, Eric R Graybill, John W Hawes. Peroxisomal metabolism of propionic acid and isobutyric acid in plants.
The Journal of biological chemistry.
2007 Aug; 282(34):24980-9. doi:
10.1074/jbc.m701028200. [PMID: 17580301] - Ryan J Mailloux, Robin Bériault, Joseph Lemire, Ranji Singh, Daniel R Chénier, Robert D Hamel, Vasu D Appanna. The tricarboxylic acid cycle, an ancient metabolic network with a novel twist.
PloS one.
2007 Aug; 2(8):e690. doi:
10.1371/journal.pone.0000690. [PMID: 17668068] - Christian G Klatt, Donald A Bryant, David M Ward. Comparative genomics provides evidence for the 3-hydroxypropionate autotrophic pathway in filamentous anoxygenic phototrophic bacteria and in hot spring microbial mats.
Environmental microbiology.
2007 Aug; 9(8):2067-78. doi:
10.1111/j.1462-2920.2007.01323.x. [PMID: 17635550] - Hae-June Lee, Chang-Mo Kang, Se-Ra Kim, Jong-Choon Kim, Chun-Sik Bae, Ki-Seok Oh, Sung-Kee Jo, Tae-Hwan Kim, Jong-Sik Jang, Sung-Ho Kim. The micronucleus frequency in cytokinesis-blocked lymphocytes of cattle in the vicinity of a nuclear power plant.
Journal of veterinary science.
2007 Jun; 8(2):117-20. doi:
10.4142/jvs.2007.8.2.117. [PMID: 17519563] - Wen Liu, Feng Wang, Huan-de Li. Simultaneous stereoselective analysis of venlafaxine and O-desmethylvenlafaxine enantiomers in human plasma by HPLC-ESI/MS using a vancomycin chiral column.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2007 May; 850(1-2):183-9. doi:
10.1016/j.jchromb.2006.11.021. [PMID: 17140867] - H Krawczyk, W Gradowska. 1H NMR spectra of methylcitric acid in urine.
Journal of inherited metabolic disease.
2007 Apr; 30(2):263. doi:
10.1007/s10545-007-0420-6. [PMID: 17295121] - Tatsuya Higashi, Akihiro Nagahama, Norihiro Otomi, Kazutake Shimada. Studies on neurosteroids XIX. Development and validation of liquid chromatography-tandem mass spectrometric method for determination of 5alpha-reduced pregnane-type neurosteroids in rat brain and serum.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2007 Apr; 848(2):188-99. doi:
10.1016/j.jchromb.2006.10.036. [PMID: 17085081] - Hye-Ran Yoon. Two step derivatization for the analyses of organic, amino acids and glycines on filter paper plasma by GC-MS/SIM.
Archives of pharmacal research.
2007 Mar; 30(3):387-95. doi:
10.1007/bf02977623. [PMID: 17424948] - Keiko Azuma, Yuko Minami, Katsunari Ippoushi, Junji Terao. Lowering effects of onion intake on oxidative stress biomarkers in streptozotocin-induced diabetic rats.
Journal of clinical biochemistry and nutrition.
2007 Mar; 40(2):131-40. doi:
10.3164/jcbn.40.131. [PMID: 18188415] - Jian-yong Feng, Quan-hong Zhu, Jia-bo Luo. [Removal of the template molecules from vinblastine-imprinted polymer].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University.
2007 Mar; 27(3):268-71. doi:
". [PMID: 17425968] - Marimuthu Srinivasan, Adluri R Sudheer, Venugopal P Menon. Ferulic Acid: therapeutic potential through its antioxidant property.
Journal of clinical biochemistry and nutrition.
2007 Mar; 40(2):92-100. doi:
10.3164/jcbn.40.92. [PMID: 18188410] - Sunil K Chattopadhyay, Satyanshu Kumar. A rapid liquid chromatography-tandem mass spectrometry method for quantification of a biologically active molecule camboginol in the extract of Garcinia cambogia.
Biomedical chromatography : BMC.
2007 Jan; 21(1):55-66. doi:
10.1002/bmc.719. [PMID: 17080506] - Marc A von Mach, Jürgen Burhenne, Ludwig S Weilemann. Accumulation of the solvent vehicle sulphobutylether beta cyclodextrin sodium in critically ill patients treated with intravenous voriconazole under renal replacement therapy.
BMC clinical pharmacology.
2006 Sep; 6(?):6. doi:
10.1186/1472-6904-6-6. [PMID: 16981986] - W D dos Santos, Maria de Lourdes Lucio Ferrarese, O Ferrarese-Filho. High performance liquid chromatography method for the determination of cinnamyl alcohol dehydrogenase activity in soybean roots.
Plant physiology and biochemistry : PPB.
2006 Jul; 44(7-9):511-5. doi:
10.1016/j.plaphy.2006.08.004. [PMID: 17023167] - Jiang-hua Zhang, Ming Jiang, Lijun Zou, Dan Shi, Su-rong Mei, Ye-xiang Zhu, Yun Shi, Kang Dai, Bin Lu. Selective solid-phase extraction of bisphenol A using molecularly imprinted polymers and its application to biological and environmental samples.
Analytical and bioanalytical chemistry.
2006 Jun; 385(4):780-6. doi:
10.1007/s00216-006-0406-5. [PMID: 16741779] - Ai-Lin Liu, Wen-Qing Lu, Zeng-Zhen Wang, Wei-Hong Chen, Wen-Hong Lu, Jing Yuan, Pei-Hong Nan, Jian-Ya Sun, Ya-Lin Zou, Li-Hong Zhou, Chi Zhang, Tang-Chun Wu. Elevated levels of urinary 8-hydroxy-2 -deoxyguanosine, lymphocytic micronuclei, and serum glutathione S-transferase in workers exposed to coke oven emissions.
Environmental health perspectives.
2006 May; 114(5):673-7. doi:
10.1289/ehp.8562. [PMID: 16675419] - Valentina Olmos, Silvia C Lenzken, Clara M López, Edda C Villaamil. High-performance liquid chromatography method for urinary trans,trans-muconic acid. Application to environmental exposure to benzene.
Journal of analytical toxicology.
2006 May; 30(4):258-61. doi:
10.1093/jat/30.4.258. [PMID: 16803664] - G Touati, V Valayannopoulos, K Mention, P de Lonlay, P Jouvet, E Depondt, M Assoun, J C Souberbielle, D Rabier, H Ogier de Baulny, J-M Saudubray. Methylmalonic and propionic acidurias: management without or with a few supplements of specific amino acid mixture.
Journal of inherited metabolic disease.
2006 Apr; 29(2-3):288-98. doi:
10.1007/s10545-006-0351-7. [PMID: 16763890] - Steven J Hallam, Tracy J Mincer, Christa Schleper, Christina M Preston, Katie Roberts, Paul M Richardson, Edward F DeLong. Pathways of carbon assimilation and ammonia oxidation suggested by environmental genomic analyses of marine Crenarchaeota.
PLoS biology.
2006 Apr; 4(4):e95. doi:
10.1371/journal.pbio.0040095. [PMID: 16533068] - K D Ivil, S H Doak, S A Jenkins, E M Parry, H G Kynaston, J M Parry, T P Stephenson. Fluorescence in-situ hybridisation on biopsies from clam ileocystoplasties and on a clam cancer.
British journal of cancer.
2006 Mar; 94(6):891-5. doi:
10.1038/sj.bjc.6603035. [PMID: 16552418] - Luciano Maestri, Sara Negri, Massimo Ferrari, Sergio Ghittori, Francesca Fabris, Paolo Danesino, Marcello Imbriani. Determination of perfluorooctanoic acid and perfluorooctanesulfonate in human tissues by liquid chromatography/single quadrupole mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2006; 20(18):2728-34. doi:
10.1002/rcm.2661. [PMID: 16915561] - Gabriela Karasová, Jozef Lehotay, Jana Sádecká, Ivan Skacáni, Miroslava Lachová. Selective extraction of derivates of p-hydroxy-benzoic acid from plant material by using a molecularly imprinted polymer.
Journal of separation science.
2005 Dec; 28(18):2468-76. doi:
10.1002/jssc.200500190. [PMID: 16405176] - Naoaki Murao, Norihisa Ohishi, Yoshiaki Nabuchi, Masaki Ishigai, Takehiko Kawanishi, Yoshinori Aso. The determination of 2beta-(3-hydroxypropoxy)-1alpha,25-dihydroxy vitamin D3 (ED-71) in human serum by high-performance liquid chromatography-electrospray tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2005 Sep; 823(2):61-8. doi:
10.1016/j.jchromb.2004.10.066. [PMID: 16102526] - Nobuyuki Suzuki, Naoto Miyashita, Akira Kotani, Fumiyo Kusu, Takao Kawasaki. Determination of troglitazone stereoisomers in rat plasma using semi-micro HPLC with electrochemical detection.
Journal of pharmaceutical and biomedical analysis.
2005 Jun; 38(1):155-61. doi:
10.1016/j.jpba.2004.12.016. [PMID: 15907634] - Frances M DuPont, Ronald Chan, Rocio Lopez, William H Vensel. Sequential extraction and quantitative recovery of gliadins, glutenins, and other proteins from small samples of wheat flour.
Journal of agricultural and food chemistry.
2005 Mar; 53(5):1575-84. doi:
10.1021/jf048697l. [PMID: 15740043] - Beate Schatter, Shenchu Jin, Konrad Löffelholz, Jochen Klein. Cross-talk between phosphatidic acid and ceramide during ethanol-induced apoptosis in astrocytes.
BMC pharmacology.
2005 Feb; 5(?):3. doi:
10.1186/1471-2210-5-3. [PMID: 15694004] - Guojun Wu, Mingzhao Xing, Elizabeth Mambo, Xin Huang, Junwei Liu, Zhongmin Guo, Aditi Chatterjee, David Goldenberg, Susanne M Gollin, Saraswati Sukumar, Barry Trink, David Sidransky. Somatic mutation and gain of copy number of PIK3CA in human breast cancer.
Breast cancer research : BCR.
2005; 7(5):R609-16. doi:
10.1186/bcr1262. [PMID: 16168105] - Michael Schwarz, Bärbel Köpcke, Roland W S Weber, Olov Sterner, Heidrun Anke. 3-hydroxypropionic acid as a nematicidal principle in endophytic fungi.
Phytochemistry.
2004 Aug; 65(15):2239-45. doi:
10.1016/j.phytochem.2004.06.035. [PMID: 15587708] - Qingyong Lang, Chien M Wai, Catharina Y W Ang, Yanyan Cui, Thomas M Heinze, Antonia Mattia, Michael Dinovi. Sample preparation and determination of ginkgo terpene trilactones in selected beverage, snack, and dietary supplement products by liquid chromatography with evaporative light-scattering detection.
Journal of AOAC International.
2004 Jul; 87(4):815-26. doi:
. [PMID: 15295874] - Yihong Lu, Hongmei Wen, Wei Li, Yumei Chi, Zhengxing Zhang. Determination of donepezil hydrochloride (E2020) in plasma by liquid chromatography-mass spectrometry and its application to pharmacokinetic studies in healthy, young, Chinese subjects.
Journal of chromatographic science.
2004 May; 42(5):234-7. doi:
10.1093/chromsci/42.5.234. [PMID: 15189594] - Toshio Naka, Rinaldo Bellomo. Bench-to-bedside review: treating acid-base abnormalities in the intensive care unit--the role of renal replacement therapy.
Critical care (London, England).
2004 Apr; 8(2):108-14. doi:
10.1186/cc2821. [PMID: 15025771] - Donald M Mock, Cindy L Henrich-Shell, Nadine Carnell, Phyllis Stumbo, Nell I Mock. 3-Hydroxypropionic acid and methylcitric acid are not reliable indicators of marginal biotin deficiency in humans.
The Journal of nutrition.
2004 Feb; 134(2):317-20. doi:
10.1093/jn/134.2.317. [PMID: 14747666] - Joel A Klappenbach, Beverly K Pierson. Phylogenetic and physiological characterization of a filamentous anoxygenic photoautotrophic bacterium ' Candidatus Chlorothrix halophila' gen. nov., sp. nov., recovered from hypersaline microbial mats.
Archives of microbiology.
2004 Jan; 181(1):17-25. doi:
10.1007/s00203-003-0615-7. [PMID: 14655000]
