β-alanine (BioDeep_00000400270)

Main id: BioDeep_00000003101

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


beta-alanine

化学式: C3H7NO2 (89.0477)
中文名称: β-丙氨酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(CN)C(=O)O
InChI: InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)

描述信息

A naturally-occurring beta-amino acid comprising propionic acid with the amino group in the 3-position.
β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.
β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.
β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.

同义名列表

6 个代谢物同义名

beta-alanine; β-alanine; 2-Carboxyethylamine; 3-Aminopropanoic acid; beta-Alanine; beta-Alanine



数据库引用编号

26 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(1)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 BDNF, CAT, DPYD, GFAP, PMP2
Endosome membrane 1 CLCN5
Nucleus 1 PMP2
cytosol 7 CAT, CLCN5, DPYD, DPYS, GFAP, GPT, PMP2
dendrite 2 BDNF, SLC6A6
Cell membrane 9 CLCN5, GLRA2, GPRC5A, MRGPRD, SLC36A1, SLC6A1, SLC6A11, SLC6A13, SLC6A6
Multi-pass membrane protein 9 CLCN5, GLRA2, GPRC5A, MRGPRD, SLC36A1, SLC6A1, SLC6A11, SLC6A13, SLC6A6
Golgi apparatus membrane 1 CLCN5
Synapse 1 GLRA2
cell surface 1 SLC6A1
Golgi apparatus 1 CLCN5
Golgi membrane 2 CLCN5, INS
lysosomal membrane 2 CLCN5, SLC36A1
neuronal cell body 2 SLC6A1, SLC6A6
presynaptic membrane 2 SLC6A1, SLC6A11
synaptic vesicle 2 BDNF, CLCN5
Presynapse 2 SLC6A1, SLC6A13
plasma membrane 9 CLCN5, GLRA2, GPRC5A, MRGPRD, SLC36A1, SLC6A1, SLC6A11, SLC6A13, SLC6A6
Membrane 9 BDNF, CAT, CLCN5, GLRA2, SLC36A1, SLC6A1, SLC6A11, SLC6A13, SLC6A6
apical plasma membrane 2 SLC36A1, SLC6A6
axon 2 BDNF, SLC6A1
basolateral plasma membrane 2 SLC6A13, SLC6A6
extracellular exosome 6 CAT, DPYS, GPRC5A, GPT, PMP2, SLC6A13
Lysosome membrane 1 SLC36A1
endoplasmic reticulum 1 SLC36A1
extracellular space 4 BDNF, IL6, INS, MRGPRD
perinuclear region of cytoplasm 1 BDNF
mitochondrion 3 ABAT, AGXT2, CAT
protein-containing complex 1 CAT
intracellular membrane-bounded organelle 3 CAT, GLRA2, GPRC5A
Secreted 3 BDNF, IL6, INS
extracellular region 4 BDNF, CAT, IL6, INS
astrocyte end-foot 1 GFAP
mitochondrial matrix 3 ABAT, AGXT2, CAT
nucleolus 1 GPRC5A
Early endosome 1 CLCN5
apical part of cell 1 CLCN5
vesicle 1 GPRC5A
postsynaptic membrane 3 SLC6A1, SLC6A11, SLC6A6
Apical cell membrane 1 SLC36A1
focal adhesion 1 CAT
GABA-ergic synapse 4 GLRA2, SLC6A1, SLC6A11, SLC6A6
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
intermediate filament 1 GFAP
Postsynaptic cell membrane 1 GLRA2
receptor complex 1 GPRC5A
neuron projection 1 GLRA2
cell projection 5 GFAP, GLRA2, SLC6A11, SLC6A13, SLC6A6
plasma membrane protein complex 1 SLC6A6
transmembrane transporter complex 1 GLRA2
Basolateral cell membrane 1 SLC6A13
microvillus membrane 1 SLC6A6
endosome lumen 1 INS
chloride channel complex 1 GLRA2
Cytoplasmic vesicle membrane 1 GPRC5A
cell body 1 GFAP
myelin sheath 1 PMP2
intermediate filament cytoskeleton 1 GFAP
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 BDNF, IL6, INS
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
postsynaptic specialization membrane 1 GLRA2
cytoplasmic side of lysosomal membrane 1 GFAP
catalase complex 1 CAT
glycinergic synapse 1 GLRA2
interleukin-6 receptor complex 1 IL6
vacuolar membrane 1 SLC36A1
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
4-aminobutyrate transaminase complex 1 ABAT


文献列表

  • Yi Jia, Xu Chen, Hui Guo, Biao Zhang, Bin Liu. Comprehensive characterization of β-alanine metabolism-related genes in HCC identified a novel prognostic signature related to clinical outcomes. Aging. 2024 Apr; 16(8):7073-7100. doi: 10.18632/aging.205744. [PMID: 38637116]
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  • Dheeraj Kumar Posa, Janice Miller, David Hoetker, Michael I Ramage, Hong Gao, Jingjing Zhao, Benjamin Doelling, Aruni Bhatnagar, Stephen J Wigmore, Richard J E Skipworth, Shahid P Baba. Skeletal muscle analysis of cancer patients reveals a potential role for carnosine in muscle wasting. Journal of cachexia, sarcopenia and muscle. 2023 May; ?(?):. doi: 10.1002/jcsm.13258. [PMID: 37199284]
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  • Doreen Dobritzsch, Judith Meijer, Rutger Meinsma, Dirk Maurer, Ardeshir A Monavari, Anders Gummesson, Annika Reims, Jorge A Cayuela, Natalia Kuklina, Jean-François Benoist, Laurence Perrin, Birgit Assmann, Georg F Hoffmann, Jörgen Bierau, Angela M Kaindl, André B P van Kuilenburg. β-Ureidopropionase deficiency due to novel and rare UPB1 mutations affecting pre-mRNA splicing and protein structural integrity and catalytic activity. Molecular genetics and metabolism. 2022 07; 136(3):177-185. doi: 10.1016/j.ymgme.2022.01.102. [PMID: 35151535]
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