meloxicam (BioDeep_00000398957)

Main id: BioDeep_00000002030

 

natural product Chemicals and Drugs


代谢物信息卡片


Meloxicam (Mobic)

化学式: C14H13N3O4S2 (351.0347458)
中文名称: 美洛昔康
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1(N(S(C2=C(C=1O)C=CC=C2)(=O)=O)C)C(=O)NC3=NC=C(S3)C
InChI: InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)

描述信息

A benzothiazine that is piroxicam in which the pyridin-2-yl group is replaced by a 5-methyl-1,3-thiazol-2-yl group. A non-steroidal anti-inflammatory drug and selective inhibitor of COX-2, it is used particularly for the management of rheumatoid arthritis.
M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AC - Oxicams
D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors
D004791 - Enzyme Inhibitors > D016861 - Cyclooxygenase Inhibitors > D052246 - Cyclooxygenase 2 Inhibitors
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor
D000893 - Anti-Inflammatory Agents

同义名列表

2 个代谢物同义名

meloxicam; Meloxicam (Mobic)



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Malihe Khorramdel, Fatemeh Peyravii Ghadikolaii, Seyed Isaac Hashemy, Hossein Javid, Masoud Homayouni Tabrizi. Nanoformulated meloxicam and rifampin: inhibiting quorum sensing and biofilm formation in Pseudomonas aeruginosa. Nanomedicine (London, England). 2024 03; 19(7):615-632. doi: 10.2217/nnm-2023-0268. [PMID: 38348578]
  • Giorgia Della Rocca, Carlo Schievano, Alessandra Di Salvo, Maria Beatrice Conti, Maria Federica Della Valle. Palmitoyl-glucosamine co-micronized with curcumin for maintenance of meloxicam-induced pain relief in dogs with osteoarthritis pain. BMC veterinary research. 2023 Feb; 19(1):37. doi: 10.1186/s12917-023-03594-4. [PMID: 36747264]
  • Shu Yuan, Jun Chen, Shuo Feng, Min Li, Yingui Sun, Yuzhen Liu. Combination anesthetic therapy: co-delivery of ropivacaine and meloxicam using transcriptional transactivator peptide modified nanostructured lipid carriers in vitro and in vivo. Drug delivery. 2022 Dec; 29(1):263-269. doi: 10.1080/10717544.2021.2023695. [PMID: 35014916]
  • Bin Chen, Hong Liu, Liang-Zhi Zhang, Jing Liu, Zhen-Feng Hong, Zhong-Biao Xiu, Hong-Jia Zhao. [Visual acupotomy intervention mitigates pain reaction by improving intervertebral disc degeneration and inhibiting apoptosis of nucleus pulposus cells in rabbits with cervical spondylosis]. Zhen ci yan jiu = Acupuncture research. 2022 Nov; 47(11):1005-11. doi: 10.13702/j.1000-0607.20220300. [PMID: 36453678]
  • Siyao Zhang, Shutong Chen, Yujing Song, Ying Xin, Ying Cui, Feng Qin. Determination of meloxicam in human plasma by ultra-high-performance liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study. Biomedical chromatography : BMC. 2022 Aug; 36(8):e5395. doi: 10.1002/bmc.5395. [PMID: 35514216]
  • Hanna Nurmi, Sauli Laaksonen, Marja Raekallio, Laura Hänninen. Wintertime pharmacokinetics of intravenously and orally administered meloxicam in semi-domesticated reindeer (Rangifer tarandus tarandus). Veterinary anaesthesia and analgesia. 2022 Jul; 49(4):423-428. doi: 10.1016/j.vaa.2022.04.005. [PMID: 35659721]
  • Saad S Enouri, Terri L O'Sullivan, Steve Ramkissoon, Robert M Friendship, Yu Gu, Ron J Johnson. Pharmacokinetics of combined administration of iron dextran with meloxicam or flunixin meglumine in piglets. The Canadian veterinary journal = La revue veterinaire canadienne. 2022 07; 63(7):727-734. doi: . [PMID: 35784780]
  • Pablo Morón-Elorza, Carlos Rojo-Solís, Teresa Álvaro-Álvarez, Mónica Valls-Torres, Daniel García-Párraga, Teresa Encinas. PHARMACOKINETICS OF MELOXICAM AFTER A SINGLE 1.5 MG/KG INTRAMUSCULAR ADMINISTRATION TO NURSEHOUND SHARKS (SCYLIORHINUS STELLARIS) AND ITS EFFECTS ON HEMATOLOGY AND PLASMA BIOCHEMISTRY. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 2022 Jun; 53(2):393-401. doi: 10.1638/2021-0144. [PMID: 35758581]
  • Miriam S Martin, Michael D Kleinhenz, Lily N Edwards-Callaway, Terry E Engle, Octavio Guimaraes, David W Schafer, Shawnee R Montgomery, Andrew K Curtis, Mikaela M Weeder, Devin R Jacobs, Johann F Coetzee. The effect of breed, sex, and oral meloxicam administration on pain biomarkers following hot-iron branding in Hereford and Angus calves. Journal of animal science. 2022 Mar; 100(3):. doi: 10.1093/jas/skac038. [PMID: 35137141]
  • Lauren P Kane, Matthew R O'Connor, Mark G Papich. PHARMACOKINETICS OF A SINGLE DOSE OF INTRAMUSCULAR AND ORAL MELOXICAM IN YELLOW STINGRAYS (UROBATIS JAMAICENSIS). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 2022 Mar; 53(1):153-158. doi: 10.1638/2021-0123. [PMID: 35339160]
  • Orhan Corum, Ertugrul Terzi, Duygu Durna Corum, Kamil Uney. Pharmacokinetics and bioavailability of meloxicam in rainbow trout (Oncorhynchus mykiss) broodstock following intravascular, intramuscular, and oral administrations. Journal of veterinary pharmacology and therapeutics. 2022 Mar; 45(2):213-219. doi: 10.1111/jvp.13031. [PMID: 34778976]
  • Juliana Cyrillo Guimarães da Silva, Eliane Dallegrave, Gabriela Zimmermann Prado Rodrigues, Cassiana Bigolin, Taís Morgana Schoffen de Oliveira Neumann, Andriéli Carolina Schuster, Juliana Machado Kayser, Luciane Beatris Mentges Staudt, Melina Floriano Moraes, Débora Graziela Farias, Gabriela Schiling, Juliana Raquel Raasch, Magda Susana Perassolo, Luciano Basso da Silva, Günther Gehlen, Andresa Heemann Betti. Repeated dose of meloxicam induces genotoxicity and histopathological changes in cardiac tissue of mice. Drug and chemical toxicology. 2022 Mar; 45(2):822-833. doi: 10.1080/01480545.2020.1778018. [PMID: 32552192]
  • G Cetin, O Corum, D D Corum, O Atik, F Altan, E Turk, I O Tekeli, H E Faki, K Uney. Pharmacokinetics of intravenous meloxicam, ketoprofen and tolfenamic acid in chukar partridge (Alectoris chukar). British poultry science. 2022 Feb; 63(1):14-20. doi: 10.1080/00071668.2021.1990211. [PMID: 34633873]
  • Yao Yu, Yang Tian, Hui Zhang, Qingxian Jia, Xuejun Chen, Dongzhou Kang, Yimeng Du, Shenghan Song, Aiping Zheng. The Evaluation of Meloxicam Nanocrystals by Oral Administration with Different Particle Sizes. Molecules (Basel, Switzerland). 2022 Jan; 27(2):. doi: 10.3390/molecules27020421. [PMID: 35056734]
  • Zhengwen Sun, Xiaoli Qu, Tianmei Wang, Feng Liu, Xue Li. Effects of Warm Acupuncture Combined with Meloxicam and Comprehensive Nursing on Pain Improvement and Joint Function in Patients with Knee Osteoarthritis. Journal of healthcare engineering. 2022; 2022(?):9167956. doi: 10.1155/2022/9167956. [PMID: 35399845]
  • Verónica Vieitez, Victor López-Rámis, Rafael Barrera, Ignacio A Gómez de Segura. Serum C-reactive protein and iron levels following gonadectomy are not modified by perioperative administration of robenacoxib to dogs. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 2022 Jan; 86(1):40-47. doi: . [PMID: 34975221]
  • Elizabeth A McCarthy, Daniel Dischino, Caroline Maguire, Silvia Leon, Rajae Talbi, Eugene Cheung, Claudio D Schteingart, Pierre J M Rivière, Susan D Reed, Robert A Steiner, Victor M Navarro. Inhibiting Kiss1 Neurons With Kappa Opioid Receptor Agonists to Treat Polycystic Ovary Syndrome and Vasomotor Symptoms. The Journal of clinical endocrinology and metabolism. 2022 01; 107(1):e328-e347. doi: 10.1210/clinem/dgab602. [PMID: 34387319]
  • Jin Yu, Yannan Wang, Yi Wu, Sisi Lin, Rui Hao, Lu Fang, Jingjing Zhu, Di Zhao, Shengjia Tong, Yongkai Si, Tiantian Ye, Zeyu Wu, Hui Huang, Feifei Zhou, Ying Wang. Pharmacokinetics of Meloxicam Tablets in Healthy Chinese Adults in the Fasting and Fed States: A Single-Site, Single-Dose, Randomized, Open, 2-Period, 2-Sequence, Crossover Bioequivalence Study. Clinical pharmacology in drug development. 2022 01; 11(1):71-79. doi: 10.1002/cpdd.965. [PMID: 34137514]
  • Lon V Kendall, Alexandrea L Bailey, Benjamin Singh, Whitney McGee. Toxic Effects of High-dose Meloxicam and Carprofen on Female CD1 Mice. Journal of the American Association for Laboratory Animal Science : JAALAS. 2022 01; 61(1):75-80. doi: 10.30802/aalas-jaalas-21-000071. [PMID: 34920791]
  • Nobuaki Ishihama, Seung-Won Choi, Yoshiteru Noutoshi, Ivana Saska, Shuta Asai, Kaori Takizawa, Sheng Yang He, Hiroyuki Osada, Ken Shirasu. Oxicam-type non-steroidal anti-inflammatory drugs inhibit NPR1-mediated salicylic acid pathway. Nature communications. 2021 12; 12(1):7303. doi: 10.1038/s41467-021-27489-w. [PMID: 34911942]
  • Cuijiao Zhan, Changmao Wang, Yaqin Wang, Haitang Xie, Jiru Chu, Rong Zhang, Rongfeng Hu, Jie Shen, Yuanwei Jia. Using a stable isotope-labeled internal standard for liquid chromatography-tandem mass spectrometry quantitation of meloxicam in human plasma. Biomedical chromatography : BMC. 2021 Dec; 35(12):e5217. doi: 10.1002/bmc.5217. [PMID: 34405424]
  • Chang-Keun Cho, Hye-Jung Park, Pureum Kang, Sungmin Moon, Yun Jeong Lee, Jung-Woo Bae, Choon-Gon Jang, Seok-Yong Lee. Physiologically based pharmacokinetic (PBPK) modeling of meloxicam in different CYP2C9 genotypes. Archives of pharmacal research. 2021 Dec; 44(12):1076-1090. doi: 10.1007/s12272-021-01361-3. [PMID: 34807366]
  • Fanxi Guo, Ying Li, Dawei Yang, Xiangyuan Jiang, Juncai Ren, Yingxue Miao, Fangyi Ding, Zugong Yu. Comparative pharmacokinetics of meloxicam oil suspension in pigs at different dosages following intramuscular administration. Research in veterinary science. 2021 Oct; 139(?):172-176. doi: 10.1016/j.rvsc.2021.07.017. [PMID: 34333251]
  • Ahmed Elfadadny, Ahmed S Mandour, Rokaia F Ragab, Khalaf F Alsharif, Gaber El-Saber Batiha, Haney Samir, Noha A Beder. A comparative time-dependent study of hematology, serum gastrin concentrations, and gastroscopic assessment of meloxicam-induced gastric ulceration in dogs. Journal of veterinary internal medicine. 2021 Sep; 35(5):2196-2204. doi: 10.1111/jvim.16253. [PMID: 34464464]
  • Darya A Kuznetsova, Leysan A Vasileva, Gulnara A Gaynanova, Elmira A Vasilieva, Oksana A Lenina, Irek R Nizameev, Marsil K Kadirov, Konstantin A Petrov, Lucia Ya Zakharova, Oleg G Sinyashin. Cationic liposomes mediated transdermal delivery of meloxicam and ketoprofen: Optimization of the composition, in vitro and in vivo assessment of efficiency. International journal of pharmaceutics. 2021 Aug; 605(?):120803. doi: 10.1016/j.ijpharm.2021.120803. [PMID: 34144135]
  • Armando Alvarez, Edwin Amirianfar, Marisa Carino Mason, Laura Huang, Jean Jose, Timothy Tiu. Extended Neuralgic Amyotrophy Syndrome in a Confirmed COVID-19 Patient After Intensive Care Unit and Inpatient Rehabilitation Stay. American journal of physical medicine & rehabilitation. 2021 08; 100(8):733-736. doi: 10.1097/phm.0000000000001795. [PMID: 34001839]
  • Orlando Salinas-Jaramillo, Alejandra Monroy-Arreola, Sebastian Herrera-Noreña, Ana L Guzmán-Ortiz, Abrahan Hernández-Hernández, Silvia Méndez-Flores, Judith Domínguez-Cherit, Noe V Duran-Figueroa, Dean J Naisbitt, Pedro Cortes-Reynosa, Eduardo Perez Salazar, Héctor Quezada, J Luis Castrejón-Flores. Extracellular Vesicles from Human Plasma Show a Distinctive Proteome and miRNome Profile in Patients with Severe Cutaneous Adverse Reactions. Chemical research in toxicology. 2021 07; 34(7):1738-1748. doi: 10.1021/acs.chemrestox.1c00047. [PMID: 34142820]
  • Hussein Akel, Ruba Ismail, Gábor Katona, Fakhara Sabir, Rita Ambrus, Ildikó Csóka. A comparison study of lipid and polymeric nanoparticles in the nasal delivery of meloxicam: Formulation, characterization, and in vitro evaluation. International journal of pharmaceutics. 2021 Jul; 604(?):120724. doi: 10.1016/j.ijpharm.2021.120724. [PMID: 34023443]
  • Diego Castineiras, Lucy Armitage, Luís Pardon Lamas, Siegrid De Baere, Siska Croubels, Ludovic Pelligand. Perioperative pharmacokinetics and pharmacodynamics of meloxicam in emus (Dromaius novaehollandiae) of different age groups using nonlinear mixed effect modelling. Journal of veterinary pharmacology and therapeutics. 2021 Jul; 44(4):603-618. doi: 10.1111/jvp.12923. [PMID: 33141479]
  • Bushra Hassan Marouf, Saad Abdulrahman Hussain, Ziyad Serdar Ali. Correlation between serum pro inflammatory cytokines and clinical scores of knee osteoarthritic patients using resveratrol as a supplementary therapy with meloxicam. Indian journal of pharmacology. 2021 Jul; 53(4):270-277. doi: 10.4103/ijp.ijp_493_20. [PMID: 34414904]
  • Marcy J Souza, Lillian E Gerhardt, Leah Shannon, Chelsey Fortner, Rebecca Davis, Megan Condon, Joan B Bergman, Sherry K Cox. Breed differences in the pharmacokinetics of orally administered meloxicam in domestic chickens (Gallus domesticus). Journal of the American Veterinary Medical Association. 2021 Jul; 259(1):84-87. doi: 10.2460/javma.259.1.84. [PMID: 34125605]
  • Erdinc Turk, Ibrahim Ozan Tekeli, Orhan Corum, Duygu Durna Corum, Fatma Ceren Kirgiz, Gul Cetin, Dilek Arslan Atessahin, Kamil Uney. Pharmacokinetics of meloxicam, carprofen, and tolfenamic acid after intramuscular and oral administration in Japanese quails (Coturnix coturnix japonica). Journal of veterinary pharmacology and therapeutics. 2021 May; 44(3):388-396. doi: 10.1111/jvp.12972. [PMID: 33846990]
  • Richard D Berkowitz, Randall J Mack, Stewart W McCallum. Meloxicam for intravenous use: review of its clinical efficacy and safety for management of postoperative pain. Pain management. 2021 May; 11(3):249-258. doi: 10.2217/pmt-2020-0082. [PMID: 33291975]
  • Jong-Shik Park, Sungmin Kim, Jaeyeon Lee, Jae-Cheol Choi, YoungAh Kim, Chun-Woong Park, Soohan Lee. Preliminary bioequivalence of an oral integrating film formulation containing meloxicam with a suspension formulation in beagle dogs. Journal of veterinary pharmacology and therapeutics. 2021 May; 44(3):342-348. doi: 10.1111/jvp.12940. [PMID: 33295645]
  • Alba M Garcia-Lino, Dafne Garcia-Mateos, Indira Alvarez-Fernandez, Esther Blanco-Paniagua, Juan M Medina, Gracia Merino, Ana I Alvarez. Role of eprinomectin as inhibitor of the ruminant ABCG2 transporter: Effects on plasma distribution of danofloxacin and meloxicam in sheep. Research in veterinary science. 2021 May; 136(?):478-483. doi: 10.1016/j.rvsc.2021.03.026. [PMID: 33838457]
  • Terry M Norton, Tonya Clauss, Rachel Sommer, Stephanie Stowell, Michelle Kaylor, Carrie Thistle, Sherry Cox. PHARMACOKINETIC BEHAVIOR OF MELOXICAM IN LOGGERHEAD (CARETTA CARETTA), KEMP'S RIDLEY (LEPIDOCHELYS KEMPII), AND GREEN (CHELONIA MYDAS) SEA TURTLES AFTER SUBCUTANEOUS ADMINISTRATION. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 2021 Apr; 52(1):295-299. doi: 10.1638/2019-0143. [PMID: 33827188]
  • Battista Borghi, Raffaele Borghi, Andrea TognÙ, Amit Lemberg, Gennaro Pipino. Recovery of post Herpes-Zoster pain, paresthesia and motor deficit with peri radicular injection of meloxicam. Minerva anestesiologica. 2021 03; 87(3):378-380. doi: 10.23736/s0375-9393.20.15086-7. [PMID: 33331747]
  • R Warner, M D Kleinhenz, J A Ydstie, J A Schleining, L W Wulf, J F Coetzee, P J Gorden. Randomized controlled trial comparison of analgesic drugs for control of pain associated with induced lameness in lactating dairy cattle. Journal of dairy science. 2021 Feb; 104(2):2040-2055. doi: 10.3168/jds.2020-18563. [PMID: 33309349]
  • Kate KuKanich, Christopher George, James K Roush, Sherry Sharp, Giosi Farace, Murthy Yerramilli, Sarah Peterson, Gregory F Grauer. Effects of low-dose meloxicam in cats with chronic kidney disease. Journal of feline medicine and surgery. 2021 02; 23(2):138-148. doi: 10.1177/1098612x20935750. [PMID: 32594827]
  • Pooja M, Gangavaram Jyothi Reddy, Kanipakam Hema, Sujatha Dodoala, Bharathi Koganti. Unravelling high-affinity binding compounds towards transmembrane protease serine 2 enzyme in treating SARS-CoV-2 infection using molecular modelling and docking studies. European journal of pharmacology. 2021 Jan; 890(?):173688. doi: 10.1016/j.ejphar.2020.173688. [PMID: 33130280]
  • Fedir V Hladkykh. The effect of meloxicam and cryopreserved placenta extract on initial inflammatory response - an experimental study. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti. 2021; 70(5):179–185. doi: 10.5817/csf2021-5-179. [PMID: 34875840]
  • Emma Nixon, Alexandra R Carlson, Patricia A Routh, Liliana Hernandez, Glen W Almond, Ronald E Baynes, Kristen M Messenger. Comparative effects of nonsteroidal anti-inflammatory drugs at castration and tail-docking in neonatal piglets. PloS one. 2021; 16(11):e0254409. doi: 10.1371/journal.pone.0254409. [PMID: 34847143]
  • M O C Clark, T C Stahl, P S Erickson. The effect of meloxicam on neonatal dairy calves: Immunoglobulin G uptake and preweaning performance. Journal of dairy science. 2020 Dec; 103(12):11363-11374. doi: 10.3168/jds.2020-18501. [PMID: 33041029]
  • Molly D Horgan, Heather K Knych, Sharon E Siksay, Rebecca S Duerr. Pharmacokinetics of a Single Dose of Oral Meloxicam in Rehabilitated Wild Brown Pelicans (Pelecanus occidentalis). Journal of avian medicine and surgery. 2020 Dec; 34(4):329-337. doi: 10.1647/1082-6742-34.4.329. [PMID: 33355409]
  • Francielli Pereira Gobbi, Paula Alessandra Di Filippo, Luciana de Macêdo Mello, Gabriela Bravim Lemos, Carla Braga Martins, Antônio Peixoto Albernaz, Celia Raquel Quirino. Effects of Flunixin Meglumine, Firocoxib, and Meloxicam in Equines After Castration. Journal of equine veterinary science. 2020 11; 94(?):103229. doi: 10.1016/j.jevs.2020.103229. [PMID: 33077071]
  • Liam E Broughton-Neiswanger, Sol M Rivera-Velez, Martin A Suarez, Jennifer E Slovak, Julianne K Hwang, Nicolas F Villarino. Pharmacometabolomics with a combination of PLS-DA and random forest algorithm analyses reveal meloxicam alters feline plasma metabolite profiles. Journal of veterinary pharmacology and therapeutics. 2020 Nov; 43(6):591-601. doi: 10.1111/jvp.12884. [PMID: 32562314]
  • Brian J Smith, Stephen M Kirschner, Lon V Kendall. Pharmacokinetics of Sustained-release, Oral, and Subcutaneous Meloxicam over 72 Hours in Male Beagle Dogs. Journal of the American Association for Laboratory Animal Science : JAALAS. 2020 11; 59(6):737-741. doi: 10.30802/aalas-jaalas-19-000155. [PMID: 32878683]
  • Emma Nixon, Travis P Mays, Patricia A Routh, James L Yeatts, Virginia R Fajt, Thomas Hairgrove, Ronald E Baynes. Plasma, urine and tissue concentrations of Flunixin and Meloxicam in Pigs. BMC veterinary research. 2020 Sep; 16(1):340. doi: 10.1186/s12917-020-02556-4. [PMID: 32938437]
  • Ibrahim Ozan Tekeli, Erdinc Turk, Duygu Durna Corum, Orhan Corum, Kamil Uney. Effect of castration procedure on the pharmacokinetics of meloxicam in goat kids. Journal of veterinary pharmacology and therapeutics. 2020 Sep; 43(5):429-434. doi: 10.1111/jvp.12872. [PMID: 32420638]
  • Kavitha Kongara, Nick Cave, Karin Weidgraaf, Venkata Sayoji Rao Dukkipati. Effect of non-steroidal anti-inflammatory drugs on glomerular filtration rate and urinary N-acetyl-β-D-glucosaminidase activity in cats after dental surgery. Veterinary anaesthesia and analgesia. 2020 Sep; 47(5):631-636. doi: 10.1016/j.vaa.2020.04.014. [PMID: 32792267]
  • Cassandra N Reedman, Todd F Duffield, Trevor J DeVries, Kerry D Lissemore, Niel A Karrow, Ziwei Li, Charlotte B Winder. Randomized control trial assessing the efficacy of pain control strategies for caustic paste disbudding in dairy calves younger than 9 days of age. Journal of dairy science. 2020 Aug; 103(8):7339-7350. doi: 10.3168/jds.2019-18118. [PMID: 32505405]
  • M A Gromova, V V Tsurko, O A Kislyak, N V Malysheva. [Evaluation of a 12-week allopurinol-lowering therapy in combination with the non-steroidal anti-inflammatory drug meloxicam in patients with gout]. Terapevticheskii arkhiv. 2020 Jul; 92(6):60-68. doi: 10.26442/00403660.2020.06.000704. [PMID: 33346494]
  • Francisco Javier Mendoza Garcia, Carlos Gonzalez-De Cara, Raul Aguilera-Aguilera, Antonio Buzon-Cuevas, Alejandro Perez-Ecija. Meloxicam ameliorates the systemic inflammatory response syndrome associated with experimentally induced endotoxemia in adult donkeys. Journal of veterinary internal medicine. 2020 Jul; 34(4):1631-1641. doi: 10.1111/jvim.15783. [PMID: 32463537]
  • Samira Rastbood, Mohammad Reza Hadjmohammadi, Seyedeh Maedeh Majidi. Development of a magnetic dispersive micro-solid-phase extraction method based on a deep eutectic solvent as a carrier for the rapid determination of meloxicam in biological samples. Analytical methods : advancing methods and applications. 2020 05; 12(18):2331-2337. doi: 10.1039/d0ay00095g. [PMID: 32930258]
  • Alba M Garcia-Lino, Esther Blanco-Paniagua, Elsa N Astorga-Simon, Laura Alvarez-Fernandez, Dafne Garcia-Mateos, Indira Alvarez-Fernandez, Ana I Alvarez, Gracia Merino. Abcg2 transporter affects plasma, milk and tissue levels of meloxicam. Biochemical pharmacology. 2020 05; 175(?):113924. doi: 10.1016/j.bcp.2020.113924. [PMID: 32217099]
  • Milad Ghani. Nanocrystalline cellulose as a biotemplate for preparation of porous titania thin film as a sorbent for thin film microextraction of ketorolac, meloxicam, diclofenac and mefenamic acid. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2020 Apr; 1142(?):122039. doi: 10.1016/j.jchromb.2020.122039. [PMID: 32163902]
  • O Bogado Pascottini, S J Van Schyndel, J F W Spricigo, M R Carvalho, B Mion, E S Ribeiro, S J LeBlanc. Effect of anti-inflammatory treatment on systemic inflammation, immune function, and endometrial health in postpartum dairy cows. Scientific reports. 2020 03; 10(1):5236. doi: 10.1038/s41598-020-62103-x. [PMID: 32251312]
  • Ying Li, Fanxi Guo, Xiangyuan Jiang, Juncai Ren, Yingxue Miao, Fangyi Ding, Zugong Yu. Pharmacokinetics and relative bioavailability of meloxicam oil suspension in pigs after intramuscular administration. Journal of veterinary pharmacology and therapeutics. 2020 Mar; 43(2):189-196. doi: 10.1111/jvp.12826. [PMID: 31880830]
  • Gergő Dargó, Dávid Bajusz, Kristóf Simon, Judit Müller, György T Balogh. Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design. Journal of medicinal chemistry. 2020 02; 63(4):1763-1774. doi: 10.1021/acs.jmedchem.0c00046. [PMID: 31995375]
  • Rui Li, Sumathy Mathialagan, Jonathan J Novak, Heather Eng, Keith Riccardi, John Litchfield. Estimation of the Effect of OAT2-Mediated Active Uptake on Meloxicam Exposure in the Human Liver. The AAPS journal. 2020 01; 22(2):20. doi: 10.1208/s12248-019-0409-8. [PMID: 31900711]
  • Tae-Won Kim, Irene Sartini, Beata Łebkowska-Wieruszewska, Andrzej Lisowski, Amnart Poapolathep, Mario Giorgi. Impact of lactation on pharmacokinetics of meloxicam in goats. Journal of veterinary pharmacology and therapeutics. 2020 Jan; 43(1):13-18. doi: 10.1111/jvp.12827. [PMID: 31774176]
  • Irene Sartini, Beata Łebkowska-Wieruszewska, Andrzej Lisowski, Amnart Poapolathep, Helen Owen, Mario Giorgi. Pharmacokinetic profiles of meloxicam after single IV and PO administration in Bilgorajska geese. Journal of veterinary pharmacology and therapeutics. 2020 Jan; 43(1):26-32. doi: 10.1111/jvp.12817. [PMID: 31579940]
  • Clóvis Ney Pinheiro Macêdo, Francisco Evanilso Silva Braga, Ana Paula Bomfim Soares Campelo, Gabriel Maia Diniz, Luiz Gonzaga de França Lopes, Marcos Kubrusly, Marcio Wilker Soares Campelo. New metallophamaceutic reduced renal injury induced by non-steroidal anti-inflammatory. Acta cirurgica brasileira. 2020; 34(12):e201901201. doi: 10.1590/s0102-865020190120000001. [PMID: 32022101]
  • Ismael Hernández-Avalos, Alexander Valverde, José Antonio Ibancovichi-Camarillo, Pedro Sánchez-Aparicio, Sergio Recillas-Morales, Jorge Osorio-Avalos, Desiderio Rodríguez-Velázquez, Agatha Elisa Miranda-Cortés. Clinical evaluation of postoperative analgesia, cardiorespiratory parameters and changes in liver and renal function tests of paracetamol compared to meloxicam and carprofen in dogs undergoing ovariohysterectomy. PloS one. 2020; 15(2):e0223697. doi: 10.1371/journal.pone.0223697. [PMID: 32059002]
  • Elke Gasthuys, Renée Houben, Roel Haesendonck, Siegrid De Baere, Stanislas U Sys, Joachim Morrens, Gunther Antonissen. Development of an in Vivo Lipopolysaccharide Inflammation Model to Study the Pharmacodynamics of COX-2 Inhibitors Celecoxib, Mavacoxib, and Meloxicam in Cockatiels (Nymphicus hollandicus). Journal of avian medicine and surgery. 2019 Dec; 33(4):349-360. doi: 10.1647/2018-391. [PMID: 31833303]
  • Sajedeh Salandari, Tahoora Shomali, Najmeh Mosleh, Saeed Nazifi. A comparative study on anti-inflammatory drug combinations in domestic pigeons with experimentally induced acute arthritis. Acta veterinaria Hungarica. 2019 12; 67(4):588-601. doi: 10.1556/004.2019.058. [PMID: 31842592]
  • N A Mitryayeva, L V Grebinyk, N E Uzlenkova. INFLUENCE OF COMBINED ACTION OF X-RADIATION AND CYCLOOXYGENASE-2 - MELOXIVET INHIBITOR ON VEGF AND PGE-2 CONTENT IN BLOOD OF RAT-TUMOR CARRIERS. Problemy radiatsiinoi medytsyny ta radiobiolohii. 2019 Dec; 24(?):261-269. doi: 10.33145/2304-8336-2019-24-261-269. [PMID: 31841472]
  • Anna E Sarfaty, Caroline J Zeiss, Amy D Willis, Jorgen M Harris, Peter C Smith. Concentration-dependent Toxicity after Subcutaneous Administration of Meloxicam to C57BL/6N Mice (Mus musculus). Journal of the American Association for Laboratory Animal Science : JAALAS. 2019 11; 58(6):802-809. doi: 10.30802/aalas-jaalas-19-000037. [PMID: 31540585]
  • M O Caldeira, R M Bruckmaier, O Wellnitz. Meloxicam affects the inflammatory responses of bovine mammary epithelial cells. Journal of dairy science. 2019 Nov; 102(11):10277-10290. doi: 10.3168/jds.2019-16630. [PMID: 31447141]
  • Ana P Costa, Michael H Court, Neal S Burke, Zhaohui Zhu, Katrina L Mealey, Nicolas F Villarino. Canine Albumin Polymorphisms and Their Impact on Drug Plasma Protein Binding. Drug metabolism and disposition: the biological fate of chemicals. 2019 10; 47(10):1024-1031. doi: 10.1124/dmd.119.087304. [PMID: 31481400]
  • O Bogado Pascottini, M R Carvalho, S J Van Schyndel, E Ticiani, J W Spricigo, L K Mamedova, E S Ribeiro, S J LeBlanc. Feed restriction to induce and meloxicam to mitigate potential systemic inflammation in dairy cows before calving. Journal of dairy science. 2019 Oct; 102(10):9285-9297. doi: 10.3168/jds.2019-16558. [PMID: 31400891]
  • Kail A Miller, Nichola J Hill, Sebastian E Carrasco, Mary M Patterson. Pharmacokinetics and Safety of Intramuscular Meloxicam in Zebra Finches (Taeniopygia guttata). Journal of the American Association for Laboratory Animal Science : JAALAS. 2019 09; 58(5):589-593. doi: 10.30802/aalas-jaalas-19-000032. [PMID: 31462348]
  • Sol M Rivera-Velez, Liam E Broughton-Neiswanger, Martin A Suarez, Jennifer E Slovak, Julianne K Hwang, Jinna Navas, Amy W S Leung, Pablo E Piñeyro, Nicolas F Villarino. Understanding the effect of repeated administration of meloxicam on feline renal cortex and medulla: A lipidomics and metabolomics approach. Journal of veterinary pharmacology and therapeutics. 2019 Jul; 42(4):476-486. doi: 10.1111/jvp.12788. [PMID: 31190341]
  • Ilse Moeremans, Mathias Devreese, Siegrid De Baere, Siska Croubels, Katleen Hermans. Pharmacokinetics and absolute oral bioavailability of meloxicam in guinea pigs (Cavia porcellus). Veterinary anaesthesia and analgesia. 2019 Jul; 46(4):548-555. doi: 10.1016/j.vaa.2018.11.011. [PMID: 31153785]
  • Shuntaro Urayama, Akane Tanaka, Kanichi Kusano, Hiroaki Sato, Tsuyoshi Nagashima, Ippei Fukuda, Chihiro Fujisawa, Hiroshi Matsuda. Oral Administration of Meloxicam Suppresses Low-Dose Endotoxin Challenge-Induced Pain in Thoroughbred Horses. Journal of equine veterinary science. 2019 06; 77(?):139-143. doi: 10.1016/j.jevs.2019.03.001. [PMID: 31133308]
  • Jun-Li Yang, Trong Tuan Dao, Tran Thi Hien, Ya-Min Zhao, Yan-Ping Shi. Further sesquiterpenoids from the rhizomes of Homalomena occulta and their anti-inflammatory activity. Bioorganic & medicinal chemistry letters. 2019 05; 29(10):1162-1167. doi: 10.1016/j.bmcl.2019.03.031. [PMID: 30928195]
  • Misha L Dunbar, Krista J Walkowiak, Jill Schappa Faustich, Aaron K Rendahl, Melanie L Graham. Preliminary Evaluation of Sustained-release Compared with Conventional Formulations of Meloxicam in Sheep (Ovis aries). Journal of the American Association for Laboratory Animal Science : JAALAS. 2019 05; 58(3):339-345. doi: 10.30802/aalas-jaalas-18-000076. [PMID: 30846026]
  • Jennifer M Pearson, Edmond A Pajor, John R Campbell, Nigel A Caulkett, Michel Levy, Craig Dorin, M Claire Windeyer. Clinical impacts of administering a nonsteroidal anti-inflammatory drug to beef calves after assisted calving on pain and inflammation, passive immunity, health, and growth. Journal of animal science. 2019 Apr; 97(5):1996-2008. doi: 10.1093/jas/skz094. [PMID: 30896739]
  • Andy Kuo, Janet R Nicholson, Laura Corradini, Maree T Smith. Establishment and characterisation of a stavudine (d4T)-induced rat model of antiretroviral toxic neuropathy (ATN) using behavioural and pharmacological methods. Inflammopharmacology. 2019 Apr; 27(2):387-396. doi: 10.1007/s10787-018-00551-8. [PMID: 30600474]
  • Cyrus Cooper, Roland Chapurlat, Nasser Al-Daghri, Gabriel Herrero-Beaumont, Olivier Bruyère, François Rannou, Roland Roth, Daniel Uebelhart, Jean-Yves Reginster. Safety of Oral Non-Selective Non-Steroidal Anti-Inflammatory Drugs in Osteoarthritis: What Does the Literature Say?. Drugs & aging. 2019 04; 36(Suppl 1):15-24. doi: 10.1007/s40266-019-00660-1. [PMID: 31073921]
  • Sol M Rivera-Velez, Liam E Broughton-Neiswanger, Martin Suarez, Pablo Piñeyro, Jinna Navas, Sandy Chen, Julianne Hwang, Nicolas F Villarino. Repeated administration of the NSAID meloxicam alters the plasma and urine lipidome. Scientific reports. 2019 03; 9(1):4303. doi: 10.1038/s41598-019-40686-4. [PMID: 30867479]
  • Silvia Imre, Amelia Tero-Vescan, Maria Titica Dogaru, László Kelemen, Daniela-Lucia Muntean, Augustin Curticapean, Noémi Szegedi, Camil-Eugen Vari. With or Without Internal Standard in HPLC Bioanalysis. A Case Study. Journal of chromatographic science. 2019 Mar; 57(3):243-248. doi: 10.1093/chromsci/bmy106. [PMID: 30615090]
  • Andrés Montesinos, Teresa Encinas, María Ardiaca, Juan A Gilabert, Cristina Bonvehí, Jorge Orós. Pharmacokinetics of meloxicam during multiple oral or intramuscular dose administration to African grey parrots (Psittacus erithacus). American journal of veterinary research. 2019 Feb; 80(2):201-207. doi: 10.2460/ajvr.80.2.201. [PMID: 30681357]
  • I G Colditz, D R Paull, J B Lloyd, L Johnston, A H Small. Efficacy of meloxicam in a pain model in sheep. Australian veterinary journal. 2019 Jan; 97(1-2):23-32. doi: 10.1111/avj.12779. [PMID: 30693494]
  • Alyssa N Woodland, Dominique Van der Saag, Benjamin Kimble, Peter J White, Merran Govendir, Sabrina Lomax. Plasma pharmacokinetic profile and efficacy of meloxicam administered subcutaneously and intramuscularly to sheep. PloS one. 2019; 14(4):e0215842. doi: 10.1371/journal.pone.0215842. [PMID: 31017959]
  • Yazun Jarrar, Qais Jarrar, Mohammad Abu-Shalhoob, Abdulqader Abed, Esra'a Sha'ban. Relative Expression of Mouse Udp-glucuronosyl Transferase 2b1 Gene in the Livers, Kidneys, and Hearts: The Influence of Nonsteroidal Anti-inflammatory Drug Treatment. Current drug metabolism. 2019; 20(11):918-923. doi: 10.2174/1389200220666191115103310. [PMID: 31733637]
  • Emmanuel Oluwasegun Adawaren, Lillian Mukandiwa, John Chipangura, Kerri Wolter, Vinny Naidoo. Percentage of faecal excretion of meloxicam in the Cape vultures (Gyps corprotheres). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2019 Jan; 215(?):41-46. doi: 10.1016/j.cbpc.2018.10.001. [PMID: 30336288]
  • Richard R Sim, Sherry K Cox. PHARMACOKINETICS OF A SUSTAINED-RELEASE FORMULATION OF MELOXICAM AFTER SUBCUTANEOUS ADMINISTRATION TO AMERICAN FLAMINGOS ( PHOENICOPTERUS RUBER). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 2018 12; 49(4):839-843. doi: 10.1638/2018-0081.1. [PMID: 30592922]
  • G E Chibisa, J R Vinyard, A H Laarman. Short communication: Effects of meloxicam administration on protein metabolism and growth performance in transported Jersey calves. Journal of dairy science. 2018 Dec; 101(12):11435-11440. doi: 10.3168/jds.2018-14493. [PMID: 30268623]
  • Vivian S K Nishihira, Barbara D Fontana, Francine R Ianiski, Hemilaine S de Almeida, Christopher P Posser, Juliane B Dias, Crystian B Parodi, Manoela M Piva, Anderson Gris, Ricardo E Mendes, Marta M M F Duarte, Michele R Sagrillo, Cristiane Luchese, Virginia C Rech, Rodrigo A Vaucher. PEGylated meloxicam-loaded nanocapsules reverse in vitro damage on caspase activity and do not induce toxicity in cultured human lymphocytes and mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2018 Nov; 107(?):1259-1267. doi: 10.1016/j.biopha.2018.08.120. [PMID: 30257340]
  • Yongzhi Tian, Xiao Wu, Mingjie Zhang, Longshan Zhao, Zhili Xiong, Feng Qin. Quantitative determination of meloxicam in dog plasma by high performance liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study. Biomedical chromatography : BMC. 2018 Jul; 32(7):e4228. doi: 10.1002/bmc.4228. [PMID: 29506317]
  • A Di Salvo, M Giorgi, S Nannarone, H K Lee, J Corsalini, G Della Rocca. Postoperative pharmacokinetics of meloxicam in horses after surgery for colic syndrome. Journal of veterinary pharmacology and therapeutics. 2018 Jun; 41(3):369-373. doi: 10.1111/jvp.12461. [PMID: 29057473]
  • Jennilee Morrison, Cheryl B Greenacre, Robert George, Sherry Cox, Tomás Martín-Jiménez. Pharmacokinetics of a Single Dose of Oral and Intramuscular Meloxicam in African Penguins ( Spheniscus demersus). Journal of avian medicine and surgery. 2018 06; 32(2):102-108. doi: 10.1647/2017-281. [PMID: 29905104]
  • Andrea L Goodnight, Sherry Cox. PHARMACOKINETICS OF MELOXICAM FOLLOWING A SINGLE ORAL DOSE IN MALAYAN FLYING FOXES ( PTEROPUS VAMPYRUS). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 2018 Jun; 49(2):307-314. doi: 10.1638/2017-0067.1. [PMID: 29900779]
  • P J Gorden, M Burchard, J A Ydstie, M D Kleinhenz, L W Wulf, S J Rajewski, C Wang, R Gehring, J P Mochel, J F Coetzee. Comparison of milk and plasma pharmacokinetics of meloxicam in postpartum versus mid-lactation Holstein cows. Journal of veterinary pharmacology and therapeutics. 2018 Jun; 41(3):463-468. doi: 10.1111/jvp.12488. [PMID: 29430684]
  • Simon Gower. Meloxicam in racing greyhounds. The Veterinary record. 2018 05; 182(18):518. doi: 10.1136/vr.k1914. [PMID: 29728485]
  • Mohsen Zeeb, Hadi Farahani, Behrooz Mirza, Mohammad Kazem Papan. Quantification of Meloxicam in Human Plasma Using Ionic Liquid-Based Ultrasound-Assisted In Situ Solvent Formation Microextraction Followed by High-Performance Liquid Chromatography. Journal of chromatographic science. 2018 May; 56(5):443-451. doi: 10.1093/chromsci/bmy012. [PMID: 31986203]
  • Melissa N Hempstead, Joseph R Waas, Mairi Stewart, Suzanne K Dowling, Vanessa M Cave, Gemma L Lowe, Mhairi A Sutherland. Effect of isoflurane alone or in combination with meloxicam on the behavior and physiology of goat kids following cautery disbudding. Journal of dairy science. 2018 Apr; 101(4):3193-3204. doi: 10.3168/jds.2017-13507. [PMID: 29397164]
  • Sonia Bahrani, Zahra Razmi, Mehrorang Ghaedi, Arash Asfaram, Hamedreza Javadian. Ultrasound-accelerated synthesis of gold nanoparticles modified choline chloride functionalized graphene oxide as a novel sensitive bioelectrochemical sensor: Optimized meloxicam detection using CCD-RSM design and application for human plasma sample. Ultrasonics sonochemistry. 2018 Apr; 42(?):776-786. doi: 10.1016/j.ultsonch.2017.12.042. [PMID: 29429731]