Flufenacet (BioDeep_00000397741)

Main id: BioDeep_00000001156

 

natural product


代谢物信息卡片


Pesticide5_Flufenacet_C14H13F4N3O2S_4-Fluoro-N-isopropyl-2-(5-trifluoromethyl-1,3,4-thiadiazol-2-yloxy)acetanilide

化学式: C14H13F4N3O2S (363.0665)
中文名称: 氟噻草胺
谱图信息: 最多检出来源 Homo sapiens(not specific) 13.51%

分子结构信息

SMILES: CC(C)N(C1=CC=C(C=C1)F)C(=O)COC2=NN=C(S2)C(F)(F)F
InChI: InChI=1S/C14H13F4N3O2S/c1-8(2)21(10-5-3-9(15)4-6-10)11(22)7-23-13-20-19-12(24-13)14(16,17)18/h3-6,8H,7H2,1-2H3



数据库引用编号

25 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 ARHGAP45, CAT, COASY, HPGDS, IGF2BP3, PIK3CA
Nucleus 3 IGF2BP3, KDR, SMARCA1
cytosol 5 ARHGAP45, CAT, HPGDS, IGF2BP3, PIK3CA
nucleoplasm 2 HPGDS, SMARCA1
Cell membrane 1 KDR
lamellipodium 1 PIK3CA
ruffle membrane 1 ARHGAP45
cell junction 1 KDR
cell surface 1 TNR
glutamatergic synapse 1 TNR
Golgi apparatus 1 KDR
endosome 1 KDR
plasma membrane 4 ARHGAP45, BCHE, KDR, PIK3CA
Membrane 2 ARHGAP45, CAT
extracellular exosome 2 CAT, COASY
endoplasmic reticulum 1 KDR
extracellular space 2 BCHE, TNR
perinuclear region of cytoplasm 1 PIK3CA
Schaffer collateral - CA1 synapse 1 TNR
intercalated disc 1 PIK3CA
mitochondrion 2 CAT, COASY
protein-containing complex 1 CAT
intracellular membrane-bounded organelle 3 CAT, HPGDS, SMARCA1
Secreted 2 BCHE, TRH
extracellular region 6 ARHGAP45, BCHE, CAT, KDR, TNR, TRH
mitochondrial outer membrane 1 COASY
[Isoform 2]: Secreted 1 KDR
Mitochondrion matrix 1 COASY
mitochondrial matrix 2 CAT, COASY
anchoring junction 1 KDR
external side of plasma membrane 1 KDR
Secreted, extracellular space, extracellular matrix 1 TNR
Cytoplasm, P-body 1 IGF2BP3
P-body 1 IGF2BP3
Early endosome 1 KDR
Cell projection, ruffle membrane 1 ARHGAP45
Membrane raft 2 KDR, TNR
focal adhesion 1 CAT
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 TNR
secretory granule 1 TRH
receptor complex 1 KDR
chromatin 1 SMARCA1
blood microparticle 1 BCHE
sorting endosome 1 KDR
Cytoplasm, Stress granule 1 IGF2BP3
cytoplasmic stress granule 1 IGF2BP3
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 ARHGAP45, CAT
endoplasmic reticulum lumen 1 BCHE
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
azurophil granule lumen 1 ARHGAP45
perineuronal net 1 TNR
nuclear envelope lumen 1 BCHE
NURF complex 1 SMARCA1
ATPase complex 1 SMARCA1
catalase complex 1 CAT
tenascin complex 1 TNR
CERF complex 1 SMARCA1
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA


文献列表

  • Evlampia Parcharidou, Rebecka Dücker, Roland Beffa. Genome-wide study of glutathione transferases and their regulation in flufenacet susceptible and resistant black-grass (Alopecurus myosuroides Huds.). Pest management science. 2024 Jun; 80(6):3035-3046. doi: 10.1002/ps.8012. [PMID: 38323683]
  • Evlampia Parcharidou, Rebecka Dücker, Peter Zöllner, Susanne Ries, Roberto Orru, Roland Beffa. Recombinant glutathione transferases from flufenacet-resistant black-grass (Alopecurus myosuroides Huds.) form different flufenacet metabolites and differ in their interaction with pre- and post-emergence herbicides. Pest management science. 2023 May; ?(?):. doi: 10.1002/ps.7523. [PMID: 37132078]
  • Rebecka Dücker, Peter Zöllner, Evlampia Parcharidou, Susanne Ries, Lothar Lorentz, Roland Beffa. Enhanced metabolism causes reduced flufenacet sensitivity in black-grass (Alopecurus myosuroides Huds.) field populations. Pest management science. 2019 Nov; 75(11):2996-3004. doi: 10.1002/ps.5414. [PMID: 30891919]
  • Rebecka Dücker, Peter Zöllner, Peter Lümmen, Susanne Ries, Alberto Collavo, Roland Beffa. Glutathione transferase plays a major role in flufenacet resistance of ryegrass (Lolium spp.) field populations. Pest management science. 2019 Nov; 75(11):3084-3092. doi: 10.1002/ps.5425. [PMID: 30920141]
  • Monika Tomkiel, Małgorzata Baćmaga, Agata Borowik, Jan Kucharski, Jadwiga Wyszkowska. Effect of a mixture of flufenacet and isoxaflutole on population numbers of soil-dwelling microorganisms, enzymatic activity of soil, and maize yield. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2019; 54(10):832-842. doi: 10.1080/03601234.2019.1636601. [PMID: 31280652]
  • Helen Metcalfe, Alice E Milne, Richard Hull, Alistair J Murdoch, Jonathan Storkey. The implications of spatially variable pre-emergence herbicide efficacy for weed management. Pest management science. 2018 Mar; 74(3):755-765. doi: 10.1002/ps.4784. [PMID: 29095563]
  • Shiho Mukaida, Takumi Ogawa, Kazuko Ohishi, Yasuhiro Tanizawa, Daisaku Ohta, Masanori Arita. The effect of rapamycin on biodiesel-producing protist Euglena gracilis. Bioscience, biotechnology, and biochemistry. 2016 Jun; 80(6):1223-9. doi: 10.1080/09168451.2016.1141040. [PMID: 26872547]
  • Donghong Wang, Qian Zhang, Yuan Zheng, Dunli Lin, Yunlong Yu. Estimating the combined toxicity of flufenacet and imazaquin to sorghum with pore water herbicide concentration. Journal of environmental sciences (China). 2016 Mar; 41(?):154-161. doi: 10.1016/j.jes.2015.04.031. [PMID: 26969061]
  • Christa Lechelt-Kunze, Ruth C Meissner, Mark Drewes, Klaus Tietjen. Flufenacet herbicide treatment phenocopies the fiddlehead mutant in Arabidopsis thaliana. Pest management science. 2003 Aug; 59(8):847-56. doi: 10.1002/ps.714. [PMID: 12916765]
  • M Bazoobandi, N T Yaduraju, G Kulshrestha. Analysis of flufenacet in soil, wheat grain and straw by gas chromatography. Journal of chromatography. A. 2000 Jul; 886(1-2):319-22. doi: 10.1016/s0021-9673(00)00429-5. [PMID: 10950301]
  • W R Christenson, B D Becker, B S Wahle, K D Moore, P D Dass, S G Lake, D L Van Goethem, B P Stuart, G K Sangha, J H Thyssen. Evidence of chemical stimulation of hepatic metabolism by an experimental acetanilide (FOE 5043) indirectly mediating reductions in circulating thyroid hormone levels in the male rat. Fundamental and applied toxicology : official journal of the Society of Toxicology. 1996 Feb; 29(2):251-9. doi: 10.1006/faat.1996.0029. [PMID: 8742323]
  • W R Christenson, B D Becker, H D Hoang, B S Wahle, K D Moore, P D Dass, S G Lake, B P Stuart, D L Van Goethem, G K Sangha. Extrathyroidally mediated changes in circulating thyroid hormone concentrations in the male rat following administration of an experimental oxyacetamide (FOE 5043). Toxicology and applied pharmacology. 1995 Jun; 132(2):253-62. doi: 10.1006/taap.1995.1106. [PMID: 7540336]