Flufenacet (BioDeep_00000001156)
Secondary id: BioDeep_00000397741
human metabolite blood metabolite
代谢物信息卡片
化学式: C14H13F4N3O2S (363.0665)
中文名称: 氟噻草胺
谱图信息:
最多检出来源 Homo sapiens(blood) 20.88%
分子结构信息
SMILES: CC(C)N(C(=O)COC1=NN=C(S1)C(F)(F)F)C1=CC=C(F)C=C1
InChI: InChI=1S/C14H13F4N3O2S/c1-8(2)21(10-5-3-9(15)4-6-10)11(22)7-23-13-20-19-12(24-13)14(16,17)18/h3-6,8H,7H2,1-2H3
描述信息
CONFIDENCE standard compound; INTERNAL_ID 255; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9423; ORIGINAL_PRECURSOR_SCAN_NO 9420
CONFIDENCE standard compound; INTERNAL_ID 255; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9408; ORIGINAL_PRECURSOR_SCAN_NO 9406
CONFIDENCE standard compound; INTERNAL_ID 255; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9375; ORIGINAL_PRECURSOR_SCAN_NO 9373
CONFIDENCE standard compound; INTERNAL_ID 255; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9386; ORIGINAL_PRECURSOR_SCAN_NO 9384
CONFIDENCE standard compound; INTERNAL_ID 255; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9401; ORIGINAL_PRECURSOR_SCAN_NO 9399
CONFIDENCE standard compound; INTERNAL_ID 255; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9344; ORIGINAL_PRECURSOR_SCAN_NO 9342
CONFIDENCE standard compound; INTERNAL_ID 8396
CONFIDENCE standard compound; INTERNAL_ID 3800
同义名列表
8 个代谢物同义名
N-(4-Fluorophenyl)-N-(1-methylethyl)-2-((5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)oxy)acetamide; N-(4-fluorophenyl)-N-(propan-2-yl)-2-{[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy}acetamide; 4-Fluoro-N-isopropyl-2-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yloxy]acetanilide; Thiafluamide; fluthiamide; Flufenacet; Flufenacet; Flufenacet
数据库引用编号
24 个数据库交叉引用编号
- ChEBI: CHEBI:81920
- KEGG: C18731
- PubChem: 86429
- HMDB: HMDB0252330
- Metlin: METLIN72506
- ChEMBL: CHEMBL1886718
- Wikipedia: Flufenacet
- chemspider: 77944
- CAS: 142459-58-3
- MoNA: AU380004
- MoNA: LU025503
- MoNA: SM839603
- MoNA: LU025502
- MoNA: AU380001
- MoNA: LU025501
- MoNA: AU380002
- MoNA: AU380003
- MoNA: AU380005
- MoNA: LU025506
- MoNA: LU025505
- MoNA: LU025504
- PMhub: MS000000055
- PubChem: 124489405
- KNApSAcK: 81920
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Evlampia Parcharidou, Rebecka Dücker, Roland Beffa. Genome-wide study of glutathione transferases and their regulation in flufenacet susceptible and resistant black-grass (Alopecurus myosuroides Huds.).
Pest management science.
2024 Jun; 80(6):3035-3046. doi:
10.1002/ps.8012. [PMID: 38323683] - Evlampia Parcharidou, Rebecka Dücker, Peter Zöllner, Susanne Ries, Roberto Orru, Roland Beffa. Recombinant glutathione transferases from flufenacet-resistant black-grass (Alopecurus myosuroides Huds.) form different flufenacet metabolites and differ in their interaction with pre- and post-emergence herbicides.
Pest management science.
2023 May; ?(?):. doi:
10.1002/ps.7523. [PMID: 37132078] - Rebecka Dücker, Peter Zöllner, Evlampia Parcharidou, Susanne Ries, Lothar Lorentz, Roland Beffa. Enhanced metabolism causes reduced flufenacet sensitivity in black-grass (Alopecurus myosuroides Huds.) field populations.
Pest management science.
2019 Nov; 75(11):2996-3004. doi:
10.1002/ps.5414. [PMID: 30891919] - Rebecka Dücker, Peter Zöllner, Peter Lümmen, Susanne Ries, Alberto Collavo, Roland Beffa. Glutathione transferase plays a major role in flufenacet resistance of ryegrass (Lolium spp.) field populations.
Pest management science.
2019 Nov; 75(11):3084-3092. doi:
10.1002/ps.5425. [PMID: 30920141] - Monika Tomkiel, Małgorzata Baćmaga, Agata Borowik, Jan Kucharski, Jadwiga Wyszkowska. Effect of a mixture of flufenacet and isoxaflutole on population numbers of soil-dwelling microorganisms, enzymatic activity of soil, and maize yield.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
2019; 54(10):832-842. doi:
10.1080/03601234.2019.1636601. [PMID: 31280652] - Helen Metcalfe, Alice E Milne, Richard Hull, Alistair J Murdoch, Jonathan Storkey. The implications of spatially variable pre-emergence herbicide efficacy for weed management.
Pest management science.
2018 Mar; 74(3):755-765. doi:
10.1002/ps.4784. [PMID: 29095563] - Shiho Mukaida, Takumi Ogawa, Kazuko Ohishi, Yasuhiro Tanizawa, Daisaku Ohta, Masanori Arita. The effect of rapamycin on biodiesel-producing protist Euglena gracilis.
Bioscience, biotechnology, and biochemistry.
2016 Jun; 80(6):1223-9. doi:
10.1080/09168451.2016.1141040. [PMID: 26872547] - Donghong Wang, Qian Zhang, Yuan Zheng, Dunli Lin, Yunlong Yu. Estimating the combined toxicity of flufenacet and imazaquin to sorghum with pore water herbicide concentration.
Journal of environmental sciences (China).
2016 Mar; 41(?):154-161. doi:
10.1016/j.jes.2015.04.031. [PMID: 26969061] - Christa Lechelt-Kunze, Ruth C Meissner, Mark Drewes, Klaus Tietjen. Flufenacet herbicide treatment phenocopies the fiddlehead mutant in Arabidopsis thaliana.
Pest management science.
2003 Aug; 59(8):847-56. doi:
10.1002/ps.714. [PMID: 12916765] - M Bazoobandi, N T Yaduraju, G Kulshrestha. Analysis of flufenacet in soil, wheat grain and straw by gas chromatography.
Journal of chromatography. A.
2000 Jul; 886(1-2):319-22. doi:
10.1016/s0021-9673(00)00429-5. [PMID: 10950301] - W R Christenson, B D Becker, B S Wahle, K D Moore, P D Dass, S G Lake, D L Van Goethem, B P Stuart, G K Sangha, J H Thyssen. Evidence of chemical stimulation of hepatic metabolism by an experimental acetanilide (FOE 5043) indirectly mediating reductions in circulating thyroid hormone levels in the male rat.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1996 Feb; 29(2):251-9. doi:
10.1006/faat.1996.0029. [PMID: 8742323] - W R Christenson, B D Becker, H D Hoang, B S Wahle, K D Moore, P D Dass, S G Lake, B P Stuart, D L Van Goethem, G K Sangha. Extrathyroidally mediated changes in circulating thyroid hormone concentrations in the male rat following administration of an experimental oxyacetamide (FOE 5043).
Toxicology and applied pharmacology.
1995 Jun; 132(2):253-62. doi:
10.1006/taap.1995.1106. [PMID: 7540336]
