L-Phosphoarginine (BioDeep_00000003479)

 

Secondary id: BioDeep_00001869277

human metabolite Endogenous


代谢物信息卡片


2-amino-5-(1-phosphonocarbamimidamido)pentanoic acid

化学式: C6H15N4O5P (254.078)
中文名称: N-磷酸- L -精氨酸锂盐水合物
谱图信息: 最多检出来源 Homo sapiens(plant) 17.34%

分子结构信息

SMILES: C(CC(C(=O)O)N)CN=C(N)NP(=O)(O)O
InChI: InChI=1S/C6H15N4O5P/c7-4(5(11)12)2-1-3-9-6(8)10-16(13,14)15/h4H,1-3,7H2,(H,11,12)(H5,8,9,10,13,14,15)



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 AK1, AK2, AK3, AK4, MYLK, PKM, RP1, TBP, TNK1
Peripheral membrane protein 2 CYP1B1, TNK1
Endoplasmic reticulum membrane 1 CYP1B1
Nucleus 7 ANKRD23, CS, PKM, RP1, RRN3, TBP, UBTF
cytosol 5 AK1, ANKRD23, MYLK, PKM, RPE
dendrite 1 SLC8A1
nucleoplasm 6 ANKRD23, ATP2B1, RRN3, SLC8A1, TBP, UBTF
Cell membrane 2 ATP2B1, SLC8A1
Cleavage furrow 1 MYLK
lamellipodium 1 MYLK
Multi-pass membrane protein 2 ATP2B1, SLC8A1
Synapse 3 ATP2B1, MYLK, SLC8A1
cell junction 1 SLC8A1
glutamatergic synapse 1 ATP2B1
Golgi membrane 1 INS
neuronal cell body 1 SLC8A1
postsynapse 1 SLC8A1
presynaptic membrane 1 ATP2B1
sarcolemma 1 SLC8A1
plasma membrane 5 ATP2B1, MYLK, PROKR1, SLC8A1, TNK1
synaptic vesicle membrane 1 ATP2B1
Membrane 5 ATP2B1, CS, CYP1B1, SLC8A1, TNK1
axon 1 SLC8A1
basolateral plasma membrane 1 ATP2B1
extracellular exosome 7 AK1, AK2, ATP2B1, CPB2, CS, PKM, RPE
extracellular space 2 CPB2, INS
intercalated disc 2 ANKRD23, SLC8A1
mitochondrion 6 AK2, AK3, AK4, CS, CYP1B1, PKM
protein-containing complex 1 TBP
intracellular membrane-bounded organelle 2 ATP2B1, CYP1B1
Microsome membrane 1 CYP1B1
postsynaptic density 1 SLC8A1
Secreted 1 INS
extracellular region 3 CPB2, INS, PKM
Mitochondrion matrix 3 AK3, AK4, CS
mitochondrial matrix 3 AK3, AK4, CS
photoreceptor connecting cilium 1 RP1
photoreceptor inner segment 1 RP1
photoreceptor outer segment 1 RP1
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
Extracellular vesicle 1 PKM
actin cytoskeleton 2 ANKRD23, MYLK
T-tubule 1 SLC8A1
Z disc 1 SLC8A1
microtubule cytoskeleton 1 RP1
nucleolus 2 RRN3, UBTF
spindle midzone 1 RP1
vesicle 1 PKM
Cell projection, lamellipodium 1 MYLK
Cytoplasm, cytoskeleton 1 RP1
focal adhesion 1 RP1
microtubule 1 RP1
Mitochondrion intermembrane space 1 AK2
mitochondrial intermembrane space 1 AK2
collagen-containing extracellular matrix 1 PKM
lateral plasma membrane 1 ATP2B1
axoneme 1 RP1
ciliary tip 1 RP1
nuclear speck 1 RP1
cilium 1 PKM
chromatin 1 TBP
microtubule associated complex 1 RP1
cell projection 1 ATP2B1
cell periphery 1 SLC8A1
[Isoform 3]: Nucleus 1 RP1
Cell projection, cilium, photoreceptor outer segment 1 RP1
Nucleus, nucleolus 2 RRN3, UBTF
Cytoplasm, cytoskeleton, cilium axoneme 1 RP1
Basolateral cell membrane 1 ATP2B1
fibrillar center 1 UBTF
endosome lumen 1 INS
I band 1 ANKRD23
microtubule organizing center 1 RP1
female germ cell nucleus 1 TBP
euchromatin 1 TBP
Presynaptic cell membrane 1 ATP2B1
sperm mitochondrial sheath 1 AK2
stress fiber 1 MYLK
ficolin-1-rich granule lumen 1 PKM
secretory granule lumen 2 INS, PKM
Golgi lumen 1 INS
endoplasmic reticulum lumen 1 INS
male germ cell nucleus 1 TBP
transcription factor TFIID complex 1 TBP
axon terminus 1 SLC8A1
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
microtubule plus-end 1 RP1
immunological synapse 1 ATP2B1
Cytoplasm, cytoskeleton, stress fiber 1 MYLK
[Isoform 1]: Nucleus 1 RP1
cytoplasmic microtubule 1 RP1
female pronucleus 1 TBP
male pronucleus 1 TBP
Rough endoplasmic reticulum 1 PKM
outer dense fiber 1 AK1
photoreceptor ribbon synapse 1 ATP2B1
[Isoform M2]: Cytoplasm 1 PKM
[Isoform M1]: Cytoplasm 1 PKM
RNA polymerase transcription factor SL1 complex 1 TBP
transcription factor TFIIA complex 1 TBP


文献列表

  • Mohamed Ibrahem Elhawy, Sylvaine Huc-Brandt, Linda Pätzold, Laila Gannoun-Zaki, Ahmed Mohamed Mostafa Abdrabou, Markus Bischoff, Virginie Molle. The Phosphoarginine Phosphatase PtpB from Staphylococcus aureus Is Involved in Bacterial Stress Adaptation during Infection. Cells. 2021 03; 10(3):. doi: 10.3390/cells10030645. [PMID: 33799337]
  • S C Forbes, L T Bish, F Ye, J Spinazzola, C Baligand, D Plant, K Vandenborne, E R Barton, H L Sweeney, G A Walter. Gene transfer of arginine kinase to skeletal muscle using adeno-associated virus. Gene therapy. 2014 Apr; 21(4):387-92. doi: 10.1038/gt.2014.9. [PMID: 24572791]
  • M Nishino, S Tsujimura, M Kuba, A Kumon. N omega-phosphoarginine phosphatase from rat renal microsome was alkaline phosphatase. Archives of biochemistry and biophysics. 1994 Jul; 312(1):101-6. doi: 10.1006/abbi.1994.1286. [PMID: 8031115]
  • S W Wu, S C Wong, D Yeung. Apparent inhibition of pyruvate kinase by phosphocreatine and phosphoarginine. Comparative biochemistry and physiology. B, Comparative biochemistry. 1979; 63(1):29-34. doi: 10.1016/0305-0491(79)90229-3. [PMID: 318398]