Machete (BioDeep_00000002817)

 

Secondary id: BioDeep_00001871728

human metabolite blood metabolite Exogenous


代谢物信息卡片


N-(butoxymethyl)-2-chloro-N-(2,6-diethylphenyl)acetamide

化学式: C17H26ClNO2 (311.1652)
中文名称: 丁草胺
谱图信息: 最多检出来源 Homo sapiens(blood) 12.79%

Reviewed

Last reviewed on 2024-08-21.

Cite this Page

Machete. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/machete (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000002817). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CCCCOCN(C(=O)CCl)C1=C(CC)C=CC=C1CC
InChI: InChI=1S/C17H26ClNO2/c1-4-7-11-21-13-19(16(20)12-18)17-14(5-2)9-8-10-15(17)6-3/h8-10H,4-7,11-13H2,1-3H3

描述信息

CONFIDENCE standard compound; INTERNAL_ID 560; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10349; ORIGINAL_PRECURSOR_SCAN_NO 10345
CONFIDENCE standard compound; INTERNAL_ID 560; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10330; ORIGINAL_PRECURSOR_SCAN_NO 10326
CONFIDENCE standard compound; INTERNAL_ID 560; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10216; ORIGINAL_PRECURSOR_SCAN_NO 10211
CONFIDENCE standard compound; INTERNAL_ID 560; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10284; ORIGINAL_PRECURSOR_SCAN_NO 10281
CONFIDENCE standard compound; INTERNAL_ID 560; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10304; ORIGINAL_PRECURSOR_SCAN_NO 10299
CONFIDENCE standard compound; INTERNAL_ID 560; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10247; ORIGINAL_PRECURSOR_SCAN_NO 10245
D010575 - Pesticides > D006540 - Herbicides
D009676 - Noxae > D002273 - Carcinogens
D016573 - Agrochemicals

同义名列表

15 个代谢物同义名

N-(butoxymethyl)-2-chloro-N-(2,6-diethylphenyl)acetamide; 2,6-Diethyl-N-butoxymethyl-alpha-chloroacetanilide; N-Butoxymethyl-alpha-chloro-2,6-diethylacetanilide; 2-Chloro-2,6-diethyl-N-(butoxymethyl)acetanilide; N-(Butoxymethyl)-2-chloro-2,6-diethylacetanilide; N-Butoxymethyl-α-chloro-2,6-diethylacetanilide; 2,6-Diethyl-N-butoxymethyl-2-chloroacetanilide; N-Butoxymethyl-a-chloro-2,6-diethylacetanilide; 2,6-Diethyl-N-butoxymethyl-α-chloroacetanilide; 2,6-Diethyl-N-butoxymethyl-a-chloroacetanilide; Butachlore; BUTACHLOR; machette; Machete; Butachlor



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

1 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 APAF1, AXIN2, BCL2, CAT, DCTN4, ENO2, HPGDS, NR5A2, S100A9
Peripheral membrane protein 2 CYP1B1, S100A9
Endoplasmic reticulum membrane 3 BCL2, CYP1B1, DIO1
Nucleus 8 APAF1, AXIN2, BCL2, DCTN4, NR5A2, S100A9, THRA, THRB
cytosol 10 APAF1, AXIN2, BCL2, CAT, DCTN4, ENO2, GPT, HPGDS, S100A9, THRA
nuclear body 1 THRB
centrosome 2 AXIN2, DCTN4
nucleoplasm 4 HPGDS, NR5A2, THRA, THRB
RNA polymerase II transcription regulator complex 3 NR5A2, THRA, THRB
Cell membrane 2 ENO2, S100A9
cell cortex 1 DCTN4
Cytoplasmic vesicle, secretory vesicle 1 CHGA
plasma membrane 6 AXIN2, BCHE, DIO1, DIO2, ENO2, S100A9
Membrane 7 APAF1, BCL2, CAT, CYP1B1, DIO1, DIO2, ENO2
extracellular exosome 6 APAF1, CAT, ENO2, GPT, S100A9, TTR
endoplasmic reticulum 1 BCL2
extracellular space 6 BCHE, CHGA, ENO2, GAST, S100A9, TTR
perinuclear region of cytoplasm 1 CHGA
mitochondrion 4 BCL2, CAT, CYP1B1, FDX1
protein-containing complex 3 APAF1, BCL2, CAT
intracellular membrane-bounded organelle 3 CAT, CYP1B1, HPGDS
Microsome membrane 1 CYP1B1
Secreted 4 BCHE, CHGA, GAST, TTR
extracellular region 7 APAF1, BCHE, CAT, CHGA, GAST, S100A9, TTR
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 3 BCL2, DIO1, DIO2
mitochondrial outer membrane 1 BCL2
Mitochondrion matrix 1 FDX1
mitochondrial matrix 2 CAT, FDX1
photoreceptor inner segment 1 ENO2
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 DCTN4
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
perikaryon 1 ENO2
beta-catenin destruction complex 1 AXIN2
pore complex 1 BCL2
Cytoplasm, cytoskeleton 2 DCTN4, S100A9
focal adhesion 2 CAT, DCTN4
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 S100A9
secretory granule 1 CHGA
Cytoplasm, myofibril, sarcomere 1 DCTN4
sarcomere 1 DCTN4
chromatin 3 NR5A2, THRA, THRB
cytoskeleton 1 S100A9
spindle pole 1 DCTN4
Cytoplasm, cell cortex 1 DCTN4
blood microparticle 1 BCHE
Endomembrane system 1 DIO1
myelin sheath 1 BCL2
stress fiber 1 DCTN4
ficolin-1-rich granule lumen 2 APAF1, CAT
secretory granule lumen 3 APAF1, CAT, S100A9
endoplasmic reticulum lumen 1 BCHE
dynactin complex 1 DCTN4
kinetochore 1 DCTN4
transport vesicle 1 CHGA
azurophil granule lumen 1 TTR
cytoplasmic dynein complex 1 DCTN4
neuronal dense core vesicle 1 CHGA
nuclear envelope lumen 1 BCHE
apoptosome 1 APAF1
Cytoplasm, cytoskeleton, stress fiber 1 DCTN4
Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle 1 CHGA
catalase complex 1 CAT
calprotectin complex 1 S100A9
S100A9 complex 1 S100A9
phosphopyruvate hydratase complex 1 ENO2
chromaffin granule 1 CHGA
BAD-BCL-2 complex 1 BCL2
[Serpinin]: Secreted 1 CHGA
[Isoform Alpha-2]: Cytoplasm 1 THRA


文献列表

  • Jing Yu, Hui Zhu, Heli Wang, Brian Shutes, Tingting Niu. Effect of butachlor on Microcystis aeruginosa: Cellular and molecular mechanisms of toxicity. Journal of hazardous materials. 2023 Feb; 449(?):131042. doi: 10.1016/j.jhazmat.2023.131042. [PMID: 36827725]
  • Wei Wang, Yanli Man, Jun Xie, Zhi Zhang, Pingping Wang, Xingang Liu. Occurrence and risk assessment of three chloroamide herbicides in water and soil environment in northeastern, eastern and southern China. Environmental research. 2023 02; 219(?):115104. doi: 10.1016/j.envres.2022.115104. [PMID: 36565672]
  • Shenggan Wu, Xinzong Zhou, Weiwei Qin, Xuehua An, Feidi Wang, Lu Lv, Tao Tang, Xinju Liu, Yueping He. Prostaglandin Metabolome Profiles in Zebrafish (Danio rerio) Exposed to Acetochlor and Butachlor. International journal of molecular sciences. 2023 Feb; 24(4):. doi: 10.3390/ijms24043488. [PMID: 36834899]
  • Na Li, Jing Jing Zhang, Jintong Liu, Nan Zhang, Hong Yang. Biodegradation of butachlor in rice intensified by a regulator of OsGT1. Ecotoxicology and environmental safety. 2022 Sep; 242(?):113942. doi: 10.1016/j.ecoenv.2022.113942. [PMID: 35926410]
  • Han Lei, Qinghao Liu, Jiapeng Leng, Hongyan Liu, Cundong Wang, Mingyue Xu, Wenqing An, Chenning Bao, Zhen Wang. Highly sensitive and selective detection of butachlor based on the resonance light scattering of doped carbon quantum dots. Analytical methods : advancing methods and applications. 2022 02; 14(6):652-660. doi: 10.1039/d1ay01356d. [PMID: 35081194]
  • Bijing Yang, Yingwei Liu, Yangwei Li, Shanshan Zhu, Yuanliang Li, Jiangnan Yi, Zhuanxu Ouyang, Bingxian Liu, Khalid Mehmood, Riaz Hussain, Jiaqiang Pan, Lianmei Hu, Zhaoxin Tang, Guanhua Wang, Ying Li, Hui Zhang. Exposure to the herbicide butachlor activates hepatic stress signals and disturbs lipid metabolism in mice. Chemosphere. 2021 Nov; 283(?):131226. doi: 10.1016/j.chemosphere.2021.131226. [PMID: 34146870]
  • Durgesh Kumar Tripthi, Rishi Kumar Varma, Swati Singh, Manisha Sachan, Gea Guerriero, Bishwajit Kumar Kushwaha, Shruti Bhardwaj, Naleeni Ramawat, Shivesh Sharma, Vijay Pratap Singh, Sheo Mohan Prasad, Devendra Kumar Chauhan, Nawal Kishore Dubey, Shivendra Sahi. Silicon tackles butachlor toxicity in rice seedlings by regulating anatomical characteristics, ascorbate-glutathione cycle, proline metabolism and levels of nutrients. Scientific reports. 2020 08; 10(1):14078. doi: 10.1038/s41598-020-65124-8. [PMID: 32826929]
  • Ehssan Torabi, Charline Wiegert, Benoît Guyot, Stéphane Vuilleumier, Gwenaël Imfeld. Dissipation of S-metolachlor and butachlor in agricultural soils and responses of bacterial communities: Insights from compound-specific isotope and biomolecular analyses. Journal of environmental sciences (China). 2020 Jun; 92(?):163-175. doi: 10.1016/j.jes.2020.02.009. [PMID: 32430119]
  • Qian Yu, Ping Zhang, Yuhan He, Zhifeng Xu, Xiulong He, Yuan Hu, Hongjun Zhang, Lin He. Dissipation Dynamics and Residue of Four Herbicides in Paddy Fields Using HPLC-MS/MS and GC-MS. International journal of environmental research and public health. 2019 01; 16(2):. doi: 10.3390/ijerph16020236. [PMID: 30650669]
  • Qianqian Geng, Jingchan Xie, Xin Wang, Mengling Cai, Hui Ma, Hanwen Ni. Preparation and Characterization of Butachlor/(2-Hydroxypropyl)-β-cyclodextrin Inclusion Complex: Improve Soil Mobility and Herbicidal Activity and Decrease Fish Toxicity. Journal of agricultural and food chemistry. 2018 Nov; 66(46):12198-12205. doi: 10.1021/acs.jafc.8b04812. [PMID: 30376318]
  • Ali Karami, Dzolkhifli Omar, James M Lazorchak, Chee Kong Yap, Zailina Hashim, Simon C Courtenay. A comparison of biomarker responses in juvenile diploid and triploid African catfish, Clarias gariepinus, exposed to the pesticide butachlor. Environmental research. 2016 Nov; 151(?):313-320. doi: 10.1016/j.envres.2016.08.006. [PMID: 27522569]
  • Zolfaghar Aladaghlo, Alireza Fakhari, Mohammad Behbahani. Efficient sample preparation method based on solvent-assisted dispersive solid-phase extraction for the trace detection of butachlor in urine and waste water samples. Journal of separation science. 2016 Oct; 39(19):3798-3805. doi: 10.1002/jssc.201600735. [PMID: 27514993]
  • Xiaoyi Liu, Zhaoxing Ling, Xing Zhou, Farooq Ahmad, Ying Zhou. Comprehensive spectroscopic probing the interaction and conformation impairment of bovine serum albumin (BSA) by herbicide butachlor. Journal of photochemistry and photobiology. B, Biology. 2016 Sep; 162(?):332-339. doi: 10.1016/j.jphotobiol.2016.07.005. [PMID: 27419617]
  • Sohrab Ahmadivand, Hamid Farahmand, Ladan Teimoori-Toolabi, Alireza Mirvaghefi, Soheil Eagderi, Tom Geerinckx, Sara Shokrpoor, Hooman Rahmati-Holasoo. Boule gene expression underpins the meiotic arrest in spermatogenesis in male rainbow trout (Oncorhynchus mykiss) exposed to DEHP and butachlor. General and comparative endocrinology. 2016 Jan; 225(?):235-241. doi: 10.1016/j.ygcen.2015.05.011. [PMID: 26027538]
  • Sohrab Ahmadivand, Hamid Farahmand, Alireza Mirvaghefi, Soheil Eagderi, Ashkan Zargar. Effects of (Anti) Androgenic Endocrine Disruptors (DEHP and Butachlor) on Immunoglobulin M (IgM) and Leukocytes Counts of Male Rainbow Trout (Oncorhynchus mykiss). Bulletin of environmental contamination and toxicology. 2015 Jun; 94(6):695-700. doi: 10.1007/s00128-015-1503-y. [PMID: 25708297]
  • Hua-Dong Xu, Jun-Song Wang, Ming-Hui Li, Yan Liu, Ting Chen, Ai-Qun Jia. (1)H NMR based metabolomics approach to study the toxic effects of herbicide butachlor on goldfish (Carassius auratus). Aquatic toxicology (Amsterdam, Netherlands). 2015 Feb; 159(?):69-80. doi: 10.1016/j.aquatox.2014.11.020. [PMID: 25528421]
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  • Changming Yang, Mengmeng Wang, Jianhua Li. Influence of rhizosphere microbial ecophysiological parameters from different plant species on butachlor degradation in a riparian soil. Journal of environmental quality. 2012 May; 41(3):716-23. doi: 10.2134/jeq2011.0223. [PMID: 22565253]
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