Teflubenzuron (BioDeep_00000002531)

   

natural product


代谢物信息卡片


Pesticide3_Teflubenzuron_C14H6Cl2F4N2O2_N-[(3,5-Dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide

化学式: C14H6Cl2F4N2O2 (379.9742)
中文名称: 氟苯脲
谱图信息: 最多检出来源 Mentha canadensis(plant) 45%

分子结构信息

SMILES: C1=CC(=C(C(=C1)F)C(=O)NC(=O)NC2=CC(=C(C(=C2F)Cl)F)Cl)F
InChI: InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)

描述信息

CONFIDENCE standard compound; EAWAG_UCHEM_ID 2931

同义名列表

3 个代谢物同义名

Teflubenzuron; Pesticide3_Teflubenzuron_C14H6Cl2F4N2O2_N-[(3,5-Dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide; Teflubenzuron



数据库引用编号

28 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 CASP3, CES1, CHI3L1, DNAJB1, SULT1B1
Nucleus 5 CASP3, CES1, DNAJB1, KDR, TRIM33
cytosol 4 CASP3, CES1, DNAJB1, SULT1B1
nucleoplasm 3 CASP3, DNAJB1, TRIM33
Cell membrane 1 KDR
Multi-pass membrane protein 1 ABCC4
cell junction 1 KDR
glutamatergic synapse 2 CASP3, DNAJB1
Golgi apparatus 2 ABCC4, KDR
neuronal cell body 2 CASP3, DNAJB1
Lysosome 1 CTBS
endosome 1 KDR
plasma membrane 3 ABCC4, BTC, KDR
Membrane 2 ABCC4, BTC
apical plasma membrane 1 ABCC4
basolateral plasma membrane 1 ABCC4
extracellular exosome 4 CHI3L1, DNAJB1, GPX3, HPR
endoplasmic reticulum 3 CES1, CHI3L1, KDR
extracellular space 5 BTC, CHI3L1, CTBS, GPX3, HPR
perinuclear region of cytoplasm 1 CHI3L1
postsynaptic density 2 CASP3, DNAJB1
Secreted 2 GPX3, HPR
extracellular region 5 BTC, CHI3L1, GPX3, HPR, KDR
[Isoform 2]: Secreted 1 KDR
anchoring junction 1 KDR
external side of plasma membrane 1 KDR
dendritic spine 1 DNAJB1
nucleolus 2 ABCC4, DNAJB1
Early endosome 1 KDR
Apical cell membrane 1 ABCC4
Cytoplasm, perinuclear region 1 CHI3L1
Membrane raft 1 KDR
extracellular matrix 1 CHI3L1
receptor complex 1 KDR
chromatin 1 TRIM33
Secreted, extracellular space 1 CHI3L1
Nucleus, nucleolus 1 DNAJB1
blood microparticle 1 HPR
Basolateral cell membrane 1 ABCC4
sorting endosome 1 KDR
Lipid droplet 1 CES1
platelet dense granule membrane 1 ABCC4
endoplasmic reticulum lumen 1 CES1
specific granule lumen 1 CHI3L1
clathrin-coated endocytic vesicle membrane 1 BTC
external side of apical plasma membrane 1 ABCC4
death-inducing signaling complex 1 CASP3
spherical high-density lipoprotein particle 1 HPR
sperm head 1 DNAJB1


文献列表

  • Diana Ilyaskina, Saúl Fernandes, Matty P Berg, Marja H Lamoree, Cornelis A M van Gestel, Pim E G Leonards. Exploring the Relationship Among Lipid Profile Changes, Growth, and Reproduction in Folsomia candida Exposed to Teflubenzuron Over Time. Environmental toxicology and chemistry. 2024 May; 43(5):1149-1160. doi: 10.1002/etc.5851. [PMID: 38517147]
  • Regis F Stacke, Daniela N Godoy, Venicius E Pretto, Fábio M Führ, Patricia da S Gubiani, Bruna L Hettwer, Cínthia G Garlet, Junior C Somavilla, Dionei S Muraro, Oderlei Bernardi. Field-evolved resistance to chitin synthesis inhibitor insecticides by soybean looper, Chrysodeixis includens (Lepidoptera: Noctuidae), in Brazil. Chemosphere. 2020 Nov; 259(?):127499. doi: 10.1016/j.chemosphere.2020.127499. [PMID: 32629314]
  • Jinghui Fang, Ole B Samuelsen, Øivind Strand, Pia Kupka Hansen, Henrice Jansen. The effects of teflubenzuron on mortality, physiology and accumulation in Capitella sp. Ecotoxicology and environmental safety. 2020 Oct; 203(?):111029. doi: 10.1016/j.ecoenv.2020.111029. [PMID: 32888609]
  • Daniela N Godoy, Fábio M Führ, Regis F Stacke, Dionei S Muraro, Paula Marçon, Holly J R Popham, Oderlei Bernardi. No cross-resistance between ChinNPV and chemical insecticides in Chrysodeixis includens (Lepidoptera: Noctuidae). Journal of invertebrate pathology. 2019 06; 164(?):66-68. doi: 10.1016/j.jip.2019.05.001. [PMID: 31078547]
  • Pål A Olsvik, Marte Aulin, Ole B Samuelsen, Rita Hannisdal, Ann-Lisbeth Agnalt, Bjørn T Lunestad. Whole-animal accumulation, oxidative stress, transcriptomic and metabolomic responses in the pink shrimp (Pandalus montagui) exposed to teflubenzuron. Journal of applied toxicology : JAT. 2019 03; 39(3):485-497. doi: 10.1002/jat.3739. [PMID: 30345541]
  • Cynthia Venâncio Ikefuti, Silvia Patrícia Carraschi, Roberto Barbuio, Claudinei da Cruz, Santiago Benites de Pádua, Eduardo Makoto Onaka, Maria José Tavares Ranzani-Paiva. Teflubenzuron as a tool for control of trichodinids in freshwater fish: Acute toxicity and in vivo efficacy. Experimental parasitology. 2015 Jul; 154(?):108-12. doi: 10.1016/j.exppara.2015.04.007. [PMID: 25913667]
  • M M Parrilla Vázquez, P Parrilla Vázquez, M Martínez Galera, A Uclés Moreno. Comparison of two ionic liquid dispersive liquid-liquid microextraction approaches for the determination of benzoylurea insecticides in wastewater using liquid chromatography-quadrupole-linear ion trap-mass spectrometry: evaluation of green parameters. Journal of chromatography. A. 2014 Aug; 1356(?):1-9. doi: 10.1016/j.chroma.2014.06.032. [PMID: 24993054]
  • Mingrong Qian, Liqin Wu, Hu Zhang, Mingfei Xu, Rui Li, Xiangyun Wang, Caixia Sun. Determination of 16 insect growth regulators in edible Chinese traditional herbs by liquid chromatography electrospray tandem mass spectrometry. Analytical and bioanalytical chemistry. 2012 Mar; 402(7):2451-62. doi: 10.1007/s00216-011-5699-3. [PMID: 22271101]
  • Fatma Acheuk, Michel Cusson, Bahia Doumandji-Mitiche. Effects of a methanolic extract of the plant Haplophyllum tuberculatum and of teflubenzuron on female reproduction in the migratory locust, Locusta migratoria (Orthoptera: Oedipodinae). Journal of insect physiology. 2012 Mar; 58(3):335-41. doi: 10.1016/j.jinsphys.2011.12.004. [PMID: 22206884]
  • F Erler, E Polat, H Demir, M Catal, G Tuna. Control of mushroom sciarid fly Lycoriella ingenua populations with insect growth regulators applied by soil drench. Journal of economic entomology. 2011 Jun; 104(3):839-44. doi: 10.1603/ec10292. [PMID: 21735902]
  • Jörg Romeis, Richard L Hellmich, Marco P Candolfi, Keri Carstens, Adinda De Schrijver, Angharad M R Gatehouse, Rod A Herman, Joseph E Huesing, Morven A McLean, Alan Raybould, Anthony M Shelton, Annabel Waggoner. Recommendations for the design of laboratory studies on non-target arthropods for risk assessment of genetically engineered plants. Transgenic research. 2011 Feb; 20(1):1-22. doi: 10.1007/s11248-010-9446-x. [PMID: 20938806]
  • Ranfeng Sun, Maoyun Lü, Li Chen, Qingshan Li, Haibin Song, Fuchun Bi, Runqiu Huang, Qingmin Wang. Design, synthesis, bioactivity, and structure-activity relationship (SAR) studies of novel benzoylphenylureas containing oxime ether group. Journal of agricultural and food chemistry. 2008 Dec; 56(23):11376-91. doi: 10.1021/jf801901h. [PMID: 18991456]
  • Heiko Vogel, Juergen Kroymann, Thomas Mitchell-Olds. Different transcript patterns in response to specialist and generalist herbivores in the wild Arabidopsis relative Boechera divaricarpa. PloS one. 2007 Oct; 2(10):e1081. doi: 10.1371/journal.pone.0001081. [PMID: 17957263]
  • R Karimzadeh, M J Hejazi, F Rahimzadeh Khoei, M Moghaddam. Laboratory evaluation of five chitin synthesis inhibitors against the colorado potato beetle, Leptinotarsa decemlineata. Journal of insect science (Online). 2007; 7(?):1-6. doi: 10.1673/031.007.5001. [PMID: 20345285]
  • A Alizadeh, M A Samih, H Izadi. Compatibility of Verticillium lecani (Zimm.) with several pesticides. Communications in agricultural and applied biological sciences. 2007; 72(4):1011-5. doi: ". [PMID: 18396843]
  • Abdel-Fattah A Khalaf. Toxicological efficacy of some indigenous dill compounds against the flesh fly, Parasarcophaga dux Thomson. Journal of the Egyptian Society of Parasitology. 2004 Apr; 34(1):227-37. doi: . [PMID: 15125529]
  • Alison S Scott Brown, Monique S J Simmonds, Wally M Blaney. Influence of a short exposure to teflubenzuron residues on the predation of thrips by Iphiseius degenerans (Acari: Phytoseiidae) and Orius laevigatus (Hemiptera: Anthocoridae). Pest management science. 2003 Nov; 59(11):1255-9. doi: 10.1002/ps.749. [PMID: 14620054]
  • Kevin Gorman, Fiona Hewitt, Ian Denholm, Gregor J Devine. New developments in insecticide resistance in the glasshouse whitefly (Trialeurodes vaporariorum) and the two-spotted spider mite (Tetranychus urticae) in the UK. Pest management science. 2002 Feb; 58(2):123-30. doi: 10.1002/ps.427. [PMID: 11852636]
  • J Koerts, A E Soffers, J W De Kraker, N H Cnubben, I M Rietjens. Metabolism of the insecticide teflubenzuron in rats. Xenobiotica; the fate of foreign compounds in biological systems. 1997 Aug; 27(8):801-17. doi: 10.1080/004982597240172. [PMID: 9293617]
  • I M el-Refai, O A Awadalla, A M Abou Zeid. Effects of some insect growth regulators on growth of Aspergillus flavus and its productivity of aflatoxin B1 and lipids. Food additives and contaminants. 1995 Jul; 12(4):585-90. doi: 10.1080/02652039509374346. [PMID: 7589721]