Meloxicam (BioDeep_00000002030)

 

Secondary id: BioDeep_00000398957

human metabolite blood metabolite Chemicals and Drugs


代谢物信息卡片


4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-2H-1λ⁶,2-benzothiazine-3-carboxamide

化学式: C14H13N3O4S2 (351.0347)
中文名称: 美洛昔康
谱图信息: 最多检出来源 Homo sapiens(plant) 28.6%

分子结构信息

SMILES: CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O
InChI: InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)

描述信息

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve the symptoms of arthritis, primary dysmenorrhea, fever; and as an analgesic, especially where there is an inflammatory component. It is closely related to piroxicam. In Europe it is marketed under the brand names Movalis, Melox, and Recoxa. In North America it is generally marketed under the brand name Mobic. In Latin America, the drug is marketed as Tenaron. [Wikipedia]
CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4454; ORIGINAL_PRECURSOR_SCAN_NO 4451
CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4456; ORIGINAL_PRECURSOR_SCAN_NO 4454
CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8780; ORIGINAL_PRECURSOR_SCAN_NO 8777
CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4467; ORIGINAL_PRECURSOR_SCAN_NO 4465
CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8736; ORIGINAL_PRECURSOR_SCAN_NO 8735
CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8828; ORIGINAL_PRECURSOR_SCAN_NO 8823
CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4500; ORIGINAL_PRECURSOR_SCAN_NO 4499
CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4466; ORIGINAL_PRECURSOR_SCAN_NO 4465
CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8798; ORIGINAL_PRECURSOR_SCAN_NO 8793
CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8836; ORIGINAL_PRECURSOR_SCAN_NO 8834
CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8839; ORIGINAL_PRECURSOR_SCAN_NO 8837
CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4468; ORIGINAL_PRECURSOR_SCAN_NO 4467
M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AC - Oxicams
D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors
D004791 - Enzyme Inhibitors > D016861 - Cyclooxygenase Inhibitors > D052246 - Cyclooxygenase 2 Inhibitors
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor
CONFIDENCE standard compound; INTERNAL_ID 1152
D000893 - Anti-Inflammatory Agents

同义名列表

15 个代谢物同义名

4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-2H-1λ⁶,2-benzothiazine-3-carboxamide; UNII-VG2QF83CGL; Meloxicamum; Reumoxicam; Miloxicam; meloxicam; Parocin; Masflex; Movalis; Movicox; Mobicox; Uticox; Mobic; Mobec; Meloxicam



数据库引用编号

37 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 AKT1, ALB, BCL2, CASP3, CAT, CYP2C9, CYP3A4, PTGS1, PTGS2, VEGFA, ZIC3
Peripheral membrane protein 3 CYP1B1, PTGS1, PTGS2
Endoplasmic reticulum membrane 6 BCL2, CYP1B1, CYP2C9, CYP3A4, PTGS1, PTGS2
Nucleus 7 AKT1, ALB, BCL2, CASP3, MPO, VEGFA, ZIC3
cytosol 5 AKT1, ALB, BCL2, CASP3, CAT
centrosome 1 ALB
nucleoplasm 4 AKT1, CASP3, MPO, ZIC3
Cell membrane 1 AKT1
lamellipodium 1 AKT1
Synapse 1 TAC1
cell cortex 1 AKT1
cell surface 1 VEGFA
glutamatergic synapse 2 AKT1, CASP3
Golgi apparatus 3 ALB, PTGS1, VEGFA
neuronal cell body 2 CASP3, TAC1
postsynapse 1 AKT1
Lysosome 1 MPO
plasma membrane 3 AKT1, CYP2C9, IFNLR1
Membrane 7 AKT1, BCL2, CAT, CYP1B1, CYP3A4, IFNLR1, VEGFA
axon 1 TAC1
caveola 1 PTGS2
extracellular exosome 5 ALB, CAT, HP, MPO, PTGS1
endoplasmic reticulum 4 ALB, BCL2, PTGS2, VEGFA
extracellular space 9 ALB, CRP, CSF3, HP, IL10, IL6, MPO, TAC1, VEGFA
lysosomal lumen 1 CSF3
adherens junction 1 VEGFA
mitochondrion 3 BCL2, CAT, CYP1B1
protein-containing complex 5 AKT1, ALB, BCL2, CAT, PTGS2
intracellular membrane-bounded organelle 6 CAT, CYP1B1, CYP2C9, CYP3A4, MPO, PTGS1
Microsome membrane 5 CYP1B1, CYP2C9, CYP3A4, PTGS1, PTGS2
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 IFNLR1
Secreted 7 ALB, CRP, CSF3, HP, IL10, IL6, VEGFA
extracellular region 10 ALB, CAT, CRP, CSF3, HP, IL10, IL6, MPO, TAC1, VEGFA
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
mitochondrial matrix 1 CAT
anchoring junction 1 ALB
photoreceptor outer segment 1 PTGS1
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
Secreted, extracellular space, extracellular matrix 1 VEGFA
microtubule cytoskeleton 1 AKT1
cell-cell junction 1 AKT1
vesicle 1 AKT1
pore complex 1 BCL2
focal adhesion 1 CAT
spindle 1 AKT1
extracellular matrix 1 VEGFA
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
secretory granule 2 MPO, VEGFA
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 2 PTGS1, PTGS2
ciliary basal body 2 AKT1, ALB
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 2 ALB, HP
Endomembrane system 1 PTGS1
myelin sheath 1 BCL2
azurophil granule 1 MPO
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 3 ALB, IL6, PTGS2
platelet alpha granule lumen 2 ALB, VEGFA
specific granule lumen 1 HP
tertiary granule lumen 1 HP
azurophil granule lumen 1 MPO
phagocytic vesicle lumen 1 MPO
death-inducing signaling complex 1 CASP3
endocytic vesicle lumen 2 CSF3, HP
haptoglobin-hemoglobin complex 1 HP
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
BAD-BCL-2 complex 1 BCL2
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
ciliary transition fiber 1 ALB
interleukin-28 receptor complex 1 IFNLR1


文献列表

  • Malihe Khorramdel, Fatemeh Peyravii Ghadikolaii, Seyed Isaac Hashemy, Hossein Javid, Masoud Homayouni Tabrizi. Nanoformulated meloxicam and rifampin: inhibiting quorum sensing and biofilm formation in Pseudomonas aeruginosa. Nanomedicine (London, England). 2024 03; 19(7):615-632. doi: 10.2217/nnm-2023-0268. [PMID: 38348578]
  • Giorgia Della Rocca, Carlo Schievano, Alessandra Di Salvo, Maria Beatrice Conti, Maria Federica Della Valle. Palmitoyl-glucosamine co-micronized with curcumin for maintenance of meloxicam-induced pain relief in dogs with osteoarthritis pain. BMC veterinary research. 2023 Feb; 19(1):37. doi: 10.1186/s12917-023-03594-4. [PMID: 36747264]
  • Shu Yuan, Jun Chen, Shuo Feng, Min Li, Yingui Sun, Yuzhen Liu. Combination anesthetic therapy: co-delivery of ropivacaine and meloxicam using transcriptional transactivator peptide modified nanostructured lipid carriers in vitro and in vivo. Drug delivery. 2022 Dec; 29(1):263-269. doi: 10.1080/10717544.2021.2023695. [PMID: 35014916]
  • Bin Chen, Hong Liu, Liang-Zhi Zhang, Jing Liu, Zhen-Feng Hong, Zhong-Biao Xiu, Hong-Jia Zhao. [Visual acupotomy intervention mitigates pain reaction by improving intervertebral disc degeneration and inhibiting apoptosis of nucleus pulposus cells in rabbits with cervical spondylosis]. Zhen ci yan jiu = Acupuncture research. 2022 Nov; 47(11):1005-11. doi: 10.13702/j.1000-0607.20220300. [PMID: 36453678]
  • Siyao Zhang, Shutong Chen, Yujing Song, Ying Xin, Ying Cui, Feng Qin. Determination of meloxicam in human plasma by ultra-high-performance liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study. Biomedical chromatography : BMC. 2022 Aug; 36(8):e5395. doi: 10.1002/bmc.5395. [PMID: 35514216]
  • Hanna Nurmi, Sauli Laaksonen, Marja Raekallio, Laura Hänninen. Wintertime pharmacokinetics of intravenously and orally administered meloxicam in semi-domesticated reindeer (Rangifer tarandus tarandus). Veterinary anaesthesia and analgesia. 2022 Jul; 49(4):423-428. doi: 10.1016/j.vaa.2022.04.005. [PMID: 35659721]
  • Saad S Enouri, Terri L O'Sullivan, Steve Ramkissoon, Robert M Friendship, Yu Gu, Ron J Johnson. Pharmacokinetics of combined administration of iron dextran with meloxicam or flunixin meglumine in piglets. The Canadian veterinary journal = La revue veterinaire canadienne. 2022 07; 63(7):727-734. doi: . [PMID: 35784780]
  • Pablo Morón-Elorza, Carlos Rojo-Solís, Teresa Álvaro-Álvarez, Mónica Valls-Torres, Daniel García-Párraga, Teresa Encinas. PHARMACOKINETICS OF MELOXICAM AFTER A SINGLE 1.5 MG/KG INTRAMUSCULAR ADMINISTRATION TO NURSEHOUND SHARKS (SCYLIORHINUS STELLARIS) AND ITS EFFECTS ON HEMATOLOGY AND PLASMA BIOCHEMISTRY. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 2022 Jun; 53(2):393-401. doi: 10.1638/2021-0144. [PMID: 35758581]
  • Miriam S Martin, Michael D Kleinhenz, Lily N Edwards-Callaway, Terry E Engle, Octavio Guimaraes, David W Schafer, Shawnee R Montgomery, Andrew K Curtis, Mikaela M Weeder, Devin R Jacobs, Johann F Coetzee. The effect of breed, sex, and oral meloxicam administration on pain biomarkers following hot-iron branding in Hereford and Angus calves. Journal of animal science. 2022 Mar; 100(3):. doi: 10.1093/jas/skac038. [PMID: 35137141]
  • Lauren P Kane, Matthew R O'Connor, Mark G Papich. PHARMACOKINETICS OF A SINGLE DOSE OF INTRAMUSCULAR AND ORAL MELOXICAM IN YELLOW STINGRAYS (UROBATIS JAMAICENSIS). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 2022 Mar; 53(1):153-158. doi: 10.1638/2021-0123. [PMID: 35339160]
  • Orhan Corum, Ertugrul Terzi, Duygu Durna Corum, Kamil Uney. Pharmacokinetics and bioavailability of meloxicam in rainbow trout (Oncorhynchus mykiss) broodstock following intravascular, intramuscular, and oral administrations. Journal of veterinary pharmacology and therapeutics. 2022 Mar; 45(2):213-219. doi: 10.1111/jvp.13031. [PMID: 34778976]
  • Juliana Cyrillo Guimarães da Silva, Eliane Dallegrave, Gabriela Zimmermann Prado Rodrigues, Cassiana Bigolin, Taís Morgana Schoffen de Oliveira Neumann, Andriéli Carolina Schuster, Juliana Machado Kayser, Luciane Beatris Mentges Staudt, Melina Floriano Moraes, Débora Graziela Farias, Gabriela Schiling, Juliana Raquel Raasch, Magda Susana Perassolo, Luciano Basso da Silva, Günther Gehlen, Andresa Heemann Betti. Repeated dose of meloxicam induces genotoxicity and histopathological changes in cardiac tissue of mice. Drug and chemical toxicology. 2022 Mar; 45(2):822-833. doi: 10.1080/01480545.2020.1778018. [PMID: 32552192]
  • G Cetin, O Corum, D D Corum, O Atik, F Altan, E Turk, I O Tekeli, H E Faki, K Uney. Pharmacokinetics of intravenous meloxicam, ketoprofen and tolfenamic acid in chukar partridge (Alectoris chukar). British poultry science. 2022 Feb; 63(1):14-20. doi: 10.1080/00071668.2021.1990211. [PMID: 34633873]
  • Yao Yu, Yang Tian, Hui Zhang, Qingxian Jia, Xuejun Chen, Dongzhou Kang, Yimeng Du, Shenghan Song, Aiping Zheng. The Evaluation of Meloxicam Nanocrystals by Oral Administration with Different Particle Sizes. Molecules (Basel, Switzerland). 2022 Jan; 27(2):. doi: 10.3390/molecules27020421. [PMID: 35056734]
  • Zhengwen Sun, Xiaoli Qu, Tianmei Wang, Feng Liu, Xue Li. Effects of Warm Acupuncture Combined with Meloxicam and Comprehensive Nursing on Pain Improvement and Joint Function in Patients with Knee Osteoarthritis. Journal of healthcare engineering. 2022; 2022(?):9167956. doi: 10.1155/2022/9167956. [PMID: 35399845]
  • Verónica Vieitez, Victor López-Rámis, Rafael Barrera, Ignacio A Gómez de Segura. Serum C-reactive protein and iron levels following gonadectomy are not modified by perioperative administration of robenacoxib to dogs. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 2022 Jan; 86(1):40-47. doi: . [PMID: 34975221]
  • Elizabeth A McCarthy, Daniel Dischino, Caroline Maguire, Silvia Leon, Rajae Talbi, Eugene Cheung, Claudio D Schteingart, Pierre J M Rivière, Susan D Reed, Robert A Steiner, Victor M Navarro. Inhibiting Kiss1 Neurons With Kappa Opioid Receptor Agonists to Treat Polycystic Ovary Syndrome and Vasomotor Symptoms. The Journal of clinical endocrinology and metabolism. 2022 01; 107(1):e328-e347. doi: 10.1210/clinem/dgab602. [PMID: 34387319]
  • Jin Yu, Yannan Wang, Yi Wu, Sisi Lin, Rui Hao, Lu Fang, Jingjing Zhu, Di Zhao, Shengjia Tong, Yongkai Si, Tiantian Ye, Zeyu Wu, Hui Huang, Feifei Zhou, Ying Wang. Pharmacokinetics of Meloxicam Tablets in Healthy Chinese Adults in the Fasting and Fed States: A Single-Site, Single-Dose, Randomized, Open, 2-Period, 2-Sequence, Crossover Bioequivalence Study. Clinical pharmacology in drug development. 2022 01; 11(1):71-79. doi: 10.1002/cpdd.965. [PMID: 34137514]
  • Lon V Kendall, Alexandrea L Bailey, Benjamin Singh, Whitney McGee. Toxic Effects of High-dose Meloxicam and Carprofen on Female CD1 Mice. Journal of the American Association for Laboratory Animal Science : JAALAS. 2022 01; 61(1):75-80. doi: 10.30802/aalas-jaalas-21-000071. [PMID: 34920791]
  • Nobuaki Ishihama, Seung-Won Choi, Yoshiteru Noutoshi, Ivana Saska, Shuta Asai, Kaori Takizawa, Sheng Yang He, Hiroyuki Osada, Ken Shirasu. Oxicam-type non-steroidal anti-inflammatory drugs inhibit NPR1-mediated salicylic acid pathway. Nature communications. 2021 12; 12(1):7303. doi: 10.1038/s41467-021-27489-w. [PMID: 34911942]
  • Cuijiao Zhan, Changmao Wang, Yaqin Wang, Haitang Xie, Jiru Chu, Rong Zhang, Rongfeng Hu, Jie Shen, Yuanwei Jia. Using a stable isotope-labeled internal standard for liquid chromatography-tandem mass spectrometry quantitation of meloxicam in human plasma. Biomedical chromatography : BMC. 2021 Dec; 35(12):e5217. doi: 10.1002/bmc.5217. [PMID: 34405424]
  • Chang-Keun Cho, Hye-Jung Park, Pureum Kang, Sungmin Moon, Yun Jeong Lee, Jung-Woo Bae, Choon-Gon Jang, Seok-Yong Lee. Physiologically based pharmacokinetic (PBPK) modeling of meloxicam in different CYP2C9 genotypes. Archives of pharmacal research. 2021 Dec; 44(12):1076-1090. doi: 10.1007/s12272-021-01361-3. [PMID: 34807366]
  • Fanxi Guo, Ying Li, Dawei Yang, Xiangyuan Jiang, Juncai Ren, Yingxue Miao, Fangyi Ding, Zugong Yu. Comparative pharmacokinetics of meloxicam oil suspension in pigs at different dosages following intramuscular administration. Research in veterinary science. 2021 Oct; 139(?):172-176. doi: 10.1016/j.rvsc.2021.07.017. [PMID: 34333251]
  • Ahmed Elfadadny, Ahmed S Mandour, Rokaia F Ragab, Khalaf F Alsharif, Gaber El-Saber Batiha, Haney Samir, Noha A Beder. A comparative time-dependent study of hematology, serum gastrin concentrations, and gastroscopic assessment of meloxicam-induced gastric ulceration in dogs. Journal of veterinary internal medicine. 2021 Sep; 35(5):2196-2204. doi: 10.1111/jvim.16253. [PMID: 34464464]
  • Darya A Kuznetsova, Leysan A Vasileva, Gulnara A Gaynanova, Elmira A Vasilieva, Oksana A Lenina, Irek R Nizameev, Marsil K Kadirov, Konstantin A Petrov, Lucia Ya Zakharova, Oleg G Sinyashin. Cationic liposomes mediated transdermal delivery of meloxicam and ketoprofen: Optimization of the composition, in vitro and in vivo assessment of efficiency. International journal of pharmaceutics. 2021 Aug; 605(?):120803. doi: 10.1016/j.ijpharm.2021.120803. [PMID: 34144135]
  • Armando Alvarez, Edwin Amirianfar, Marisa Carino Mason, Laura Huang, Jean Jose, Timothy Tiu. Extended Neuralgic Amyotrophy Syndrome in a Confirmed COVID-19 Patient After Intensive Care Unit and Inpatient Rehabilitation Stay. American journal of physical medicine & rehabilitation. 2021 08; 100(8):733-736. doi: 10.1097/phm.0000000000001795. [PMID: 34001839]
  • Orlando Salinas-Jaramillo, Alejandra Monroy-Arreola, Sebastian Herrera-Noreña, Ana L Guzmán-Ortiz, Abrahan Hernández-Hernández, Silvia Méndez-Flores, Judith Domínguez-Cherit, Noe V Duran-Figueroa, Dean J Naisbitt, Pedro Cortes-Reynosa, Eduardo Perez Salazar, Héctor Quezada, J Luis Castrejón-Flores. Extracellular Vesicles from Human Plasma Show a Distinctive Proteome and miRNome Profile in Patients with Severe Cutaneous Adverse Reactions. Chemical research in toxicology. 2021 07; 34(7):1738-1748. doi: 10.1021/acs.chemrestox.1c00047. [PMID: 34142820]
  • Hussein Akel, Ruba Ismail, Gábor Katona, Fakhara Sabir, Rita Ambrus, Ildikó Csóka. A comparison study of lipid and polymeric nanoparticles in the nasal delivery of meloxicam: Formulation, characterization, and in vitro evaluation. International journal of pharmaceutics. 2021 Jul; 604(?):120724. doi: 10.1016/j.ijpharm.2021.120724. [PMID: 34023443]
  • Diego Castineiras, Lucy Armitage, Luís Pardon Lamas, Siegrid De Baere, Siska Croubels, Ludovic Pelligand. Perioperative pharmacokinetics and pharmacodynamics of meloxicam in emus (Dromaius novaehollandiae) of different age groups using nonlinear mixed effect modelling. Journal of veterinary pharmacology and therapeutics. 2021 Jul; 44(4):603-618. doi: 10.1111/jvp.12923. [PMID: 33141479]
  • Bushra Hassan Marouf, Saad Abdulrahman Hussain, Ziyad Serdar Ali. Correlation between serum pro inflammatory cytokines and clinical scores of knee osteoarthritic patients using resveratrol as a supplementary therapy with meloxicam. Indian journal of pharmacology. 2021 Jul; 53(4):270-277. doi: 10.4103/ijp.ijp_493_20. [PMID: 34414904]
  • Marcy J Souza, Lillian E Gerhardt, Leah Shannon, Chelsey Fortner, Rebecca Davis, Megan Condon, Joan B Bergman, Sherry K Cox. Breed differences in the pharmacokinetics of orally administered meloxicam in domestic chickens (Gallus domesticus). Journal of the American Veterinary Medical Association. 2021 Jul; 259(1):84-87. doi: 10.2460/javma.259.1.84. [PMID: 34125605]
  • Erdinc Turk, Ibrahim Ozan Tekeli, Orhan Corum, Duygu Durna Corum, Fatma Ceren Kirgiz, Gul Cetin, Dilek Arslan Atessahin, Kamil Uney. Pharmacokinetics of meloxicam, carprofen, and tolfenamic acid after intramuscular and oral administration in Japanese quails (Coturnix coturnix japonica). Journal of veterinary pharmacology and therapeutics. 2021 May; 44(3):388-396. doi: 10.1111/jvp.12972. [PMID: 33846990]
  • Richard D Berkowitz, Randall J Mack, Stewart W McCallum. Meloxicam for intravenous use: review of its clinical efficacy and safety for management of postoperative pain. Pain management. 2021 May; 11(3):249-258. doi: 10.2217/pmt-2020-0082. [PMID: 33291975]
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