Beclometasone (BioDeep_00000001895)

   

natural product


代谢物信息卡片


beclomethasone

化学式: C22H29ClO5 (408.17034140000004)
中文名称: 倍氯米松
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(Cl)C(O)CC2(C)C1(O)C(=O)CO
InChI: InChI=1S/C22H29ClO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1

描述信息

A - Alimentary tract and metabolism > A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents > A07E - Intestinal antiinflammatory agents > A07EA - Corticosteroids acting locally
R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03B - Other drugs for obstructive airway diseases, inhalants > R03BA - Glucocorticoids
D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07A - Corticosteroids, plain > D07AC - Corticosteroids, potent (group iii)
R - Respiratory system > R01 - Nasal preparations > R01A - Decongestants and other nasal preparations for topical use > R01AD - Corticosteroids
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents
D000893 - Anti-Inflammatory Agents

同义名列表

2 个代谢物同义名

beclomethasone; Beclometasone



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Sali Ahmed, Yanjia Cao, Zicheng Wang, Matthew M Coates, Pakwanja Twea, Mingyang Ma, Jonathan Chiwanda Banda, Emily Wroe, Lan Bai, David A Watkins, Yanfang Su. Service readiness for the management of non-communicable diseases in publicly financed facilities in Malawi: findings from the 2019 Harmonised Health Facility Assessment census survey. BMJ open. 2024 01; 14(1):e072511. doi: 10.1136/bmjopen-2023-072511. [PMID: 38176873]
  • Iftikhar Khan, Ali Al-Hasani, Mohsin H Khan, Aamir N Khan, Fakhr-E -Alam, Sajid K Sadozai, Abdelbary Elhissi, Jehanzeb Khan, Sakib Yousaf. Impact of dispersion media and carrier type on spray-dried proliposome powder formulations loaded with beclomethasone dipropionate for their pulmonary drug delivery via a next generation impactor. PloS one. 2023; 18(3):e0281860. doi: 10.1371/journal.pone.0281860. [PMID: 36913325]
  • Piotr Kuna, Joanna Jerzynska, Matteo Martini, Andrea Vele, Irene Barneschi, Fabrizia Mariotti, George Georges, Giorgia Ciurlia. Pharmacokinetics of extrafine beclometasone dipropionate/formoterol fumarate/glycopyrronium bromide in adolescent and adult patients with asthma. Pharmacology research & perspectives. 2022 08; 10(4):e980. doi: 10.1002/prp2.980. [PMID: 35733414]
  • Zhu Luo, Germano Lucci, Luigi Santoro, Eva Topole, Fabrizia Mariotti. Pharmacokinetic profile of beclometasone dipropionate/formoterol fumarate administered through a novel dry-powder inhaler in Chinese healthy volunteers. Pulmonary pharmacology & therapeutics. 2022 06; 73-74(?):102129. doi: 10.1016/j.pupt.2022.102129. [PMID: 35525480]
  • Bob Geng, Anne E Dixon, Jinnie Ko, Pranathi Janampally, Tmirah Haselkorn, Cecile T J Holweg, Thomas B Casale, Nizar Jarjour. Impact of body mass index on omalizumab response in adults with moderate-to-severe allergic asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2022 05; 128(5):553-560. doi: 10.1016/j.anai.2022.01.025. [PMID: 35101644]
  • Naoki Harada, Yumi Arahori, Mai Okuyama, Paula B Luis, Akil I Joseph, Tomoya Kitakaze, Naoki Goshima, Claus Schneider, Hiroshi Inui, Ryoichi Yamaji. Curcumin activates G protein-coupled receptor 97 (GPR97) in a manner different from glucocorticoid. Biochemical and biophysical research communications. 2022 03; 595(?):41-46. doi: 10.1016/j.bbrc.2022.01.075. [PMID: 35093639]
  • Fahad H Alahmadi, Brian Keevil, Lynn Elsey, Kate George, Robert Niven, Stephen J Fowler. Serum Inhaled Corticosteroid Detection for Monitoring Adherence in Severe Asthma. The journal of allergy and clinical immunology. In practice. 2021 12; 9(12):4279-4287.e6. doi: 10.1016/j.jaip.2021.05.041. [PMID: 34153519]
  • Massimo Cella, Jörg Täubel, Irisz Delestre-Levai, Anne Tulard, Andrea Vele, George Georges. Ethnic Sensitivity Study of the Extrafine, Single-Inhaler, Triple Therapy Beclomethasone Dipropionate, Formoterol Fumarate, and Glycopyrronium Bromide Pressurized Metered Dose Inhaler in Japanese and Caucasian Healthy Individuals: A Randomized, Double-Blind, Single-Dose Crossover Study. Clinical therapeutics. 2021 11; 43(11):1934-1947.e4. doi: 10.1016/j.clinthera.2021.09.001. [PMID: 34600734]
  • Hongli Fan, Yaxiong Liu, Jiamei Dong, Zhuoya Luo. Screening Aptamers that Are Specific for Beclomethasone and the Development of Quantum Dot-Based Assay. Applied biochemistry and biotechnology. 2021 Oct; 193(10):3139-3150. doi: 10.1007/s12010-021-03585-x. [PMID: 34085169]
  • Jonathan Fishman, Edward W Fisher. Long-term olfactory dysfunction following coronavirus disease 2019 infection, routine neck dissection at salvage laryngectomy, parotid incidentalomas, and prescribing intranasal steroids in HIV infection. The Journal of laryngology and otology. 2021 Sep; 135(9):753-754. doi: 10.1017/s0022215121002218. [PMID: 34448688]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Iftikhar Khan, Sozan Hussein, Chahinez Houacine, Sajid Khan Sadozai, Yamir Islam, Ruba Bnyan, Abdelbary Elhissi, Sakib Yousaf. Fabrication, characterization and optimization of nanostructured lipid carrier formulations using Beclomethasone dipropionate for pulmonary drug delivery via medical nebulizers. International journal of pharmaceutics. 2021 Apr; 598(?):120376. doi: 10.1016/j.ijpharm.2021.120376. [PMID: 33617949]
  • Jie Shao, Yaning Wang, Guenther Hochhaus. Semi-mechanistic PK/PD model to assess pulmonary targeting of beclomethasone dipropionate and its active metabolite. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2021 Apr; 159(?):105699. doi: 10.1016/j.ejps.2021.105699. [PMID: 33444744]
  • Daisuke Miyazawa, Gen Kaneko. Clinical trials of inhaled beclomethasone and mometasone for COVID-19 should be conducted. Journal of medical virology. 2021 02; 93(2):637-638. doi: 10.1002/jmv.26413. [PMID: 32776550]
  • Can Peng, Dongjie Xiao, Haiyan Chen, Lijie Rao, Haiyan Xiao, Huahua Li. Effects of beclomethasone and aminophylline combined with enteral nutrition in chronic obstructive pulmonary disease on nutritional status and immune function in elders. Asia Pacific journal of clinical nutrition. 2021; 30(1):60-66. doi: 10.6133/apjcn.202103_30(1).0008. [PMID: 33787041]
  • Chao Hu, Jia Miao, Shiqing Shu, Ying Wang, Xiaohong Zhu, Zhu Luo. Pharmacokinetics, pharmacodynamics and safety of a novel extrafine BDP/FF/GB combination delivered via metered-dose inhaler in healthy Chinese subjects. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2020 Mar; 144(?):105198. doi: 10.1016/j.ejps.2019.105198. [PMID: 31862312]
  • Qingyu Yao, Yuchen Guo, Junsheng Xue, Daming Kong, Jian Li, Xiuyun Tian, Chunyi Hao, Tianyan Zhou. Development and validation of a LC-MS/MS method for simultaneous determination of six glucocorticoids and its application to a pharmacokinetic study in nude mice. Journal of pharmaceutical and biomedical analysis. 2020 Feb; 179(?):112980. doi: 10.1016/j.jpba.2019.112980. [PMID: 31744668]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Amira Sa Said, Salahdein AbuRuz, Henry Chrystyn. Bioavailability of Beclometasone From Two HFA-BDP Formulations With a Spacer. Respiratory care. 2019 Oct; 64(10):1222-1230. doi: 10.4187/respcare.06689. [PMID: 31138731]
  • Vincenzo De Leo, Silvia Ruscigno, Adriana Trapani, Sante Di Gioia, Francesco Milano, Delia Mandracchia, Roberto Comparelli, Stefano Castellani, Angela Agostiano, Giuseppe Trapani, Lucia Catucci, Massimo Conese. Preparation of drug-loaded small unilamellar liposomes and evaluation of their potential for the treatment of chronic respiratory diseases. International journal of pharmaceutics. 2018 Jul; 545(1-2):378-388. doi: 10.1016/j.ijpharm.2018.04.030. [PMID: 29678545]
  • Calvin J Small, Michael Gillespie. Pharmacokinetics of Beclomethasone Dipropionate Delivered by Breath-Actuated Inhaler and Metered-Dose Inhaler in Healthy Subjects. Journal of aerosol medicine and pulmonary drug delivery. 2018 06; 31(3):182-190. doi: 10.1089/jamp.2017.1397. [PMID: 28937845]
  • Iftikhar Khan, Sakib Yousaf, Sneha Subramanian, Mohamed Albed Alhnan, Waqar Ahmed, Abdelbary Elhissi. Proliposome tablets manufactured using a slurry-driven lipid-enriched powders: Development, characterization and stability evaluation. International journal of pharmaceutics. 2018 Mar; 538(1-2):250-262. doi: 10.1016/j.ijpharm.2017.12.049. [PMID: 29337185]
  • Iftikhar Khan, Sakib Yousaf, Sneha Subramanian, Mohamed Albed Alhnan, Waqar Ahmed, Abdelbary Elhissi. Proliposome Powders for the Generation of Liposomes: the Influence of Carbohydrate Carrier and Separation Conditions on Crystallinity and Entrapment of a Model Antiasthma Steroid. AAPS PharmSciTech. 2018 Jan; 19(1):262-274. doi: 10.1208/s12249-017-0793-2. [PMID: 28698930]
  • Bo Chawes, Erik Nilsson, Sarah Nørgaard, Anna Dossing, Li Mortensen, Hans Bisgaard. Knemometry is more sensitive to systemic effects of inhaled corticosteroids in children with asthma than 24-hour urine cortisol excretion. The Journal of allergy and clinical immunology. 2017 Aug; 140(2):431-436. doi: 10.1016/j.jaci.2016.09.041. [PMID: 28012663]
  • Fabrizia Mariotti, Giorgia Ciurlia, Luca Spaccapelo, Annamaria Muraro, Daniela Acerbi. A Two-Period Open-Label, Single-Dose Crossover Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Between Cimetidine and Inhaled Extrafine CHF 5993. European journal of drug metabolism and pharmacokinetics. 2017 Apr; 42(2):269-279. doi: 10.1007/s13318-016-0345-2. [PMID: 27209586]
  • A Kugelman, M Peniakov, S Zangen, Y Shiff, A Riskin, A Iofe, I Shoris, D Bader, S Arnon. Inhaled hydrofluoalkane-beclomethasone dipropionate in bronchopulmonary dysplasia. A double-blind, randomized, controlled pilot study. Journal of perinatology : official journal of the California Perinatal Association. 2017 02; 37(2):197-202. doi: 10.1038/jp.2016.177. [PMID: 27735931]
  • Alejandra Cimato, Andres Hoyos Obando, Graciela Facorro, María Martínez Sarrasague. Analysis of the structure and surfactant activity of novel formulations containing exogenous pulmonary surfactant and glucocorticoids. Respiratory physiology & neurobiology. 2016 11; 233(?):33-40. doi: 10.1016/j.resp.2016.07.009. [PMID: 27476933]
  • Giorgio Bozzini, Marco Provenzano, Nicolò Buffi, Mauro Seveso, Giovanni Lughezzani, Giorgio Guazzoni, Alberto Mandressi, Gianluigi Taverna. An observational study of the use of beclomethasone dipropionate suppositories in the treatment of lower urinary tract inflammation in men. BMC urology. 2016 Jun; 16(1):25. doi: 10.1186/s12894-016-0144-8. [PMID: 27267961]
  • Luigi Margiotta-Casaluci, Stewart F Owen, Belinda Huerta, Sara Rodríguez-Mozaz, Subramanian Kugathas, Damià Barceló, Mariann Rand-Weaver, John P Sumpter. Internal exposure dynamics drive the Adverse Outcome Pathways of synthetic glucocorticoids in fish. Scientific reports. 2016 02; 6(?):21978. doi: 10.1038/srep21978. [PMID: 26917256]
  • Iftikhar Khan, Sakib Yousaf, Sneha Subramanian, Oshadie Korale, Mohamed Albed Alhnan, Waqar Ahmed, Kevin M G Taylor, Abdelbary Elhissi. Proliposome powders prepared using a slurry method for the generation of beclometasone dipropionate liposomes. International journal of pharmaceutics. 2015 Dec; 496(2):342-50. doi: 10.1016/j.ijpharm.2015.10.002. [PMID: 26456265]
  • Piotr Kuna, Mirco Govoni, Germano Lucci, Mario Scuri, Daniela Acerbi, Iwona Stelmach. Pharmacokinetics and pharmacodynamics of an extrafine fixed pMDI combination of beclometasone dipropionate/formoterol fumarate in adolescent asthma. British journal of clinical pharmacology. 2015 Sep; 80(3):569-80. doi: 10.1111/bcp.12640. [PMID: 25808292]
  • Frank C Hampel, Nicholas A Nayak, Nathan Segall, Calvin J Small, Jiang Li, Sudeesh K Tantry. No hypothalamic-pituitary-adrenal function effect with beclomethasone dipropionate nasal aerosol, based on 24-hour serum cortisol in pediatric allergic rhinitis. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2015 Aug; 115(2):137-42. doi: 10.1016/j.anai.2015.05.019. [PMID: 26250771]
  • Joe K Gerald, Lynn B Gerald, Monica M Vasquez, Wayne J Morgan, Susan J Boehmer, Robert F Lemanske, David T Mauger, Robert C Strunk, Stanley J Szefler, Robert S Zeiger, Leonard B Bacharier, Elizabeth Bade, Ronina A Covar, Theresa W Guilbert, Hengameh Heidarian-Raissy, H William Kelly, Jonathan Malka-Rais, Christine A Sorkness, Lynn M Taussig, Vernon M Chinchilli, Fernando D Martinez. Markers of Differential Response to Inhaled Corticosteroid Treatment Among Children with Mild Persistent Asthma. The journal of allergy and clinical immunology. In practice. 2015 Jul; 3(4):540-6.e3. doi: 10.1016/j.jaip.2015.01.023. [PMID: 25783161]
  • Simona Boncompagni, Lewis Arthurton, Eugene Akujuru, Timothy Pearson, Dietmar Steverding, Feliciano Protasi, Gabriel Mutungi. Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres. The Journal of physiology. 2015 Jun; 593(12):2679-92. doi: 10.1113/jp270502. [PMID: 25846902]
  • Bethanie M Carney Almroth, Lina M Gunnarsson, Filip Cuklev, Jerker Fick, Erik Kristiansson, D G Joakim Larsson. Waterborne beclomethasone dipropionate affects the physiology of fish while its metabolite beclomethasone is not taken up. The Science of the total environment. 2015 Apr; 511(?):37-46. doi: 10.1016/j.scitotenv.2014.12.016. [PMID: 25527967]
  • Boška Hrvačić, Kristina Šitum, Koraljka Đurić, Berislav Bošnjak, Željko Ferenčić, Karmen Brajša, Stribor Marković, Ines Glojnarić. Relative potencies of three glucocorticoids to induce hypoplasia of the physis and concomitant biochemical alterations in the rat. Drug and chemical toxicology. 2015; 38(3):272-7. doi: 10.3109/01480545.2014.947502. [PMID: 25109225]
  • William J Anderson, Philip M Short, Peter A Williamson, Arvind Manoharan, Brian J Lipworth. The inverse agonist propranolol confers no corticosteroid-sparing activity in mild-to-moderate persistent asthma. Clinical science (London, England : 1979). 2014 12; 127(11):635-43. doi: 10.1042/cs20140249. [PMID: 24938324]
  • Andreas B Jordy, Annette K Serup, Kristian Karstoft, Henriette Pilegaard, Bente Kiens, Jacob Jeppesen. Insulin sensitivity is independent of lipid binding protein trafficking at the plasma membrane in human skeletal muscle: effect of a 3-day, high-fat diet. American journal of physiology. Regulatory, integrative and comparative physiology. 2014 Nov; 307(9):R1136-45. doi: 10.1152/ajpregu.00124.2014. [PMID: 25163924]
  • F J Stokes, L M Bailey, A Ganguli, A S Davison. Assessment of endogenous, oral and inhaled steroid cross-reactivity in the Roche cortisol immunoassay. Annals of clinical biochemistry. 2014 Jul; 51(Pt 4):503-6. doi: 10.1177/0004563213509793. [PMID: 24150482]
  • Hyouk-Soo Kwon, Tae-Bum Kim, Yoon Su Lee, Seung-Hwan Jeong, Yun-Jeong Bae, Keun-Ai Moon, Bo-Ram Bang, Hee-Bom Moon, You Sook Cho. Clusterin expression level correlates with increased oxidative stress in asthmatics. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2014 Mar; 112(3):217-21. doi: 10.1016/j.anai.2013.12.012. [PMID: 24428970]
  • Vipul Yadav, Simon Gaisford, Hamid A Merchant, Abdul W Basit. Colonic bacterial metabolism of corticosteroids. International journal of pharmaceutics. 2013 Nov; 457(1):268-74. doi: 10.1016/j.ijpharm.2013.09.007. [PMID: 24055438]
  • Subramaniam Kugathas, Tamsin J Runnalls, John P Sumpter. Metabolic and reproductive effects of relatively low concentrations of beclomethasone dipropionate, a synthetic glucocorticoid, on fathead minnows. Environmental science & technology. 2013 Aug; 47(16):9487-95. doi: 10.1021/es4019332. [PMID: 23869980]
  • Sarita D Boyd, Colleen Hadigan, Maryellen McManus, Cheryl Chairez, Lynnette K Nieman, Alice K Pau, Raul M Alfaro, Joseph A Kovacs, Monica M Calderon, Scott R Penzak. Influence of low-dose ritonavir with and without darunavir on the pharmacokinetics and pharmacodynamics of inhaled beclomethasone. Journal of acquired immune deficiency syndromes (1999). 2013 Jul; 63(3):355-61. doi: 10.1097/qai.0b013e31829260d6. [PMID: 23535292]
  • Bo L K Chawes, Annalisa Piccinno, Eskil Kreiner-Møller, Nadja H Vissing, Porntiva Poorisrisak, Li Mortensen, Erik Nilson, Amalie Bisgaard, Anna Dossing, Maja Deleuran, Nanna L Skytt, Nasim Samandari, Francesco Sergio, Giorgia Ciurlia, Gianluigi Poli, Daniela Acerbi, Hans Bisgaard. Pharmacokinetic comparison of inhaled fixed combination vs. the free combination of beclomethasone and formoterol pMDIs in asthmatic children. British journal of clinical pharmacology. 2013 Apr; 75(4):1081-8. doi: 10.1111/j.1365-2125.2012.04459.x. [PMID: 22978252]
  • Daniel J Warner, Hongming Chen, Louis-David Cantin, J Gerry Kenna, Simone Stahl, Clare L Walker, Tobias Noeske. Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals. 2012 Dec; 40(12):2332-41. doi: 10.1124/dmd.112.047068. [PMID: 22961681]
  • Paul H Ratner, S David Miller, Frank C Hampel, Amy Melchior, Stephanie A Dunbar, Sudeesh K Tantry. Once-daily treatment with beclomethasone dipropionate nasal aerosol does not affect hypothalamic-pituitary-adrenal axis function. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2012 Nov; 109(5):336-41. doi: 10.1016/j.anai.2012.08.005. [PMID: 23062389]
  • Amira S A Said, Lindsay P Harding, Henry Chrystyn. Urinary pharmacokinetic methodology to determine the relative lung bioavailability of inhaled beclometasone dipropionate. British journal of clinical pharmacology. 2012 Sep; 74(3):456-64. doi: 10.1111/j.1365-2125.2012.04210.x. [PMID: 22299644]
  • Paul H Ratner, Amy Melchior, Stephanie A Dunbar, Sudeesh K Tantry, Paul M Dorinsky. Pharmacokinetic profile of beclomethasone dipropionate hydrofluoroalkane after intranasal administration versus oral inhalation in healthy subjects: results of a single-dose, randomized, open-label, 3-period crossover study. Clinical therapeutics. 2012 Jun; 34(6):1422-31. doi: 10.1016/j.clinthera.2012.04.023. [PMID: 22621776]
  • Keivan Gohari Moghaddam, Negin Rashidi, Hamidreza Aghaei Meybodi, Nader Rezaie, Mahdi Montazeri, Ramin Heshmat, Zohreh Annabestani. The effect of inhaled corticosteroids on hypothalamic-pituitary-adrenal axis. Indian journal of pharmacology. 2012 May; 44(3):314-8. doi: 10.4103/0253-7613.96300. [PMID: 22701238]
  • A Chiappori, C Folli, A M Riccio, E Caci, D Descalzi, L De Ferrari, E Ingrassia, G Nicolini, G W Canonica. Salbutamol: how does it enter smooth muscle cells?. International journal of immunopathology and pharmacology. 2012 Apr; 25(2):541-6. doi: 10.1177/039463201202500227. [PMID: 22697089]
  • O M Ige, A G Falade, O G Arinola. Atopy is a risk factor for adult asthma in urban community of Southwestern Nigeria. Lung India : official organ of Indian Chest Society. 2012 Apr; 29(2):114-9. doi: 10.4103/0970-2113.95301. [PMID: 22628923]
  • Surujpal Teelucksingh, Sarada Jaimungal, Lexley Pinto Pereira, Terence Seemungal, Shivananda Nayak. Does insulin resistance co-exist with glucocorticoid resistance in the metabolic syndrome? Studies comparing skin sensitivity to glucocorticoids in individuals with and without acanthosis nigricans. Cardiovascular diabetology. 2012 Mar; 11(?):31. doi: 10.1186/1475-2840-11-31. [PMID: 22462579]
  • Ricardo Martins Duarte Byrro, Isabela Costa César, Fabiana Fernandes de Santana e Silva Cardoso, Iram Moreira Mundim, Leonardo de Souza Teixeira, Ricardo Rodrigues Bonfim, Sandro Antônio Gomes, Gerson Antônio Pianetti. A rapid and sensitive HPLC-APCI-MS/MS method determination of fluticasone in human plasma: application for a bioequivalency study in nasal spray formulations. Journal of pharmaceutical and biomedical analysis. 2012 Mar; 61(?):38-43. doi: 10.1016/j.jpba.2011.11.018. [PMID: 22178434]
  • Radka Saldova, Jennifer E Huffman, Barbara Adamczyk, Ana Mužinić, Jayesh J Kattla, Maja Pučić, Mislav Novokmet, Jodie L Abrahams, Caroline Hayward, Igor Rudan, Sarah H Wild, Alan F Wright, Ozren Polašek, Gordan Lauc, Harry Campbell, James F Wilson, Pauline M Rudd. Association of medication with the human plasma N-glycome. Journal of proteome research. 2012 Mar; 11(3):1821-31. doi: 10.1021/pr2010605. [PMID: 22256781]
  • Kaori Hara, Hiroyuki Tsujimoto, C C Huang, Yoshiaki Kawashima, Rie Ando, Osamu Kusuoka, Kazutoshi Tamura, Masahiro Tsutsumi. Ultrastructural and Immunohistochemical Studies on Uptake and Distribution of FITC-Conjugated PLGA Nanoparticles Administered Intratracheally in Rats. Journal of toxicologic pathology. 2012 Mar; 25(1):19-26. doi: 10.1293/tox.25.19. [PMID: 22481855]
  • Shao Lin, Jean Pierre W Munsie, Michele L Herdt-Losavio, Charlotte M Druschel, Kimberly Campbell, Marilyn L Browne, Paul A Romitti, Richard S Olney, Erin M Bell. Maternal asthma medication use and the risk of selected birth defects. Pediatrics. 2012 Feb; 129(2):e317-24. doi: 10.1542/peds.2010-2660. [PMID: 22250027]
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