Diethylpropion (BioDeep_00000001887)
Secondary id: BioDeep_00001867957
human metabolite blood metabolite Chemicals and Drugs Volatile Flavor Compounds
代谢物信息卡片
化学式: C13H19NO (205.14665639999998)
中文名称: 二乙基丙酮, 安非拉酮
谱图信息:
最多检出来源 Homo sapiens(blood) 26.09%
分子结构信息
SMILES: CCN(CC)C(C)C(=O)C1=CC=CC=C1
InChI: InChI=1S/C13H19NO/c1-4-14(5-2)11(3)13(15)12-9-7-6-8-10-12/h6-11H,4-5H2,1-3H3
描述信息
Diethylpropion is only found in individuals that have used or taken this drug. It is a appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)Diethylpropion is an amphetamine that stimulates neurons to release or maintain high levels of a particular group of neurotransmitters known as catecholamines; these include dopamine and norepinephrine. High levels of these catecholamines tend to suppress hunger signals and appetite. Diethylpropion (through catecholamine elevation) may also indirectly affect leptin levels in the brain. It is theorized that diethylpropion can raise levels of leptin which signal satiety. It is also theorized that increased levels of the catecholamines are partially responsible for halting another chemical messenger known as neuropeptide Y. This peptide initiates eating, decreases energy expenditure, and increases fat storage.
A - Alimentary tract and metabolism > A08 - Antiobesity preparations, excl. diet products > A08A - Antiobesity preparations, excl. diet products > A08AA - Centrally acting antiobesity products
C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant
D019440 - Anti-Obesity Agents > D001067 - Appetite Depressants
C78272 - Agent Affecting Nervous System > C29728 - Anorexiant
同义名列表
60 个代谢物同义名
Investigacion farmaceutica brand OF amfepramone hydrochloride; Marion merrell dow brand OF amfepramone hydrochloride; Marion merrell brand OF amfepramone hydrochloride; Artegodan brand OF amfepramone hydrochloride; Théranol brand OF amfepramone hydrochloride; Temmler brand OF amfepramone hydrochloride; Pro DOC brand OF amfepramone hydrochloride; Vortech brand OF amfepramone hydrochloride; Hoechst brand OF amfepramone hydrochloride; Crinex brand OF amfepramone hydrochloride; Uriach brand OF amfepramone hydrochloride; Nadeau brand OF amfepramone hydrochloride; Medix brand OF amfepramone hydrochloride; Medic brand OF amfepramone hydrochloride; Dexo brand OF amfepramone hydrochloride; 3m Brand OF amfepramone hydrochloride; 2-(diethylamino)-1-phenylpropan-1-one; 2-(Diethylamino)-1-phenyl-1-propanone; 1-Phenyl-2-diethylamino-1-propanone; alpha-Diethylaminopropiophenone; Hydrochloride, diethylpropion; 2-(Diethylamino)propiophenone; Diethylpropion Hydrochloride; 2-Diethylaminopropiophenone; Α-diethylaminopropiophenone; a-Diethylaminopropiophenone; alpha-Benzoyltriethylamine; Α-benzoyltriethylamine; a-Benzoyltriethylamine; (+-)-Diethylpropion; (S)-diethylpropion; Diethylcathinone; Diethylpropione; Diethylpropion; Dietil-retard; Dietil retard; Amfepramonum; DEA no. 1610; Dietilretard; Anfepramona; Amfepramone; Amfepramon; Norex, ifa; Préfamone; Ifa norex; Phepranon; Modératan; Nobesine; Delgamer; Regibon; Maruate; Tenuate; Tepanil; Propion; Regenon; Lipomin; Anorex; Neobes; Diethylpropion; Diethylpropion
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:4530
- KEGG: C06954
- KEGGdrug: D07444
- PubChem: 7029
- HMDB: HMDB0015072
- Metlin: METLIN2009
- DrugBank: DB00937
- ChEMBL: CHEMBL1194666
- Wikipedia: Diethylpropion
- MeSH: Diethylpropion
- chemspider: 6762
- CAS: 90-84-6
- PMhub: MS000001388
- PubChem: 9169
- NIKKAJI: J4.327C
- RefMet: Diethylpropion
- KNApSAcK: 4530
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
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