(+/-)-Mandelamide (BioDeep_00001883322)

   


代谢物信息卡片


2-Hydroxy-2-phenylacetamide

化学式: C8H9NO2 (151.0633)
中文名称: (+/-)-扁桃酰胺, 扁桃酰胺, 2-羟基-2-苯基乙酰胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)C(C(=O)N)O
InChI: InChI=1S/C8H9NO2/c9-8(11)7(10)6-4-2-1-3-5-6/h1-5,7,10H,(H2,9,11)

描述信息

D000890 - Anti-Infective Agents > D000892 - Anti-Infective Agents, Urinary > D008333 - Mandelic Acids

同义名列表

3 个代谢物同义名

2-Hydroxy-2-phenylacetamide; (+/-)-Mandelamide; 2-Hydroxy-2-phenylacetamide



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ADIG, CEBPB, EIF2AK2, NR3C1, PPARG
Endoplasmic reticulum membrane 2 FAAH, HSP90B1
Nucleus 7 ADIG, CEBPA, CEBPB, EIF2AK2, HSP90B1, NR3C1, PPARG
cytosol 4 EIF2AK2, HSP90B1, NR3C1, PPARG
centrosome 1 NR3C1
nucleoplasm 5 CEBPA, CEBPB, EIF2AK2, NR3C1, PPARG
RNA polymerase II transcription regulator complex 3 CEBPA, CEBPB, PPARG
Multi-pass membrane protein 1 FAAH
Synapse 1 NR3C1
glutamatergic synapse 1 FAAH
postsynapse 1 FAAH
smooth endoplasmic reticulum 1 HSP90B1
Presynapse 1 FAAH
Membrane 5 ADIG, EIF2AK2, FAAH, HSP90B1, NR3C1
extracellular exosome 1 HSP90B1
endoplasmic reticulum 2 FAAH, HSP90B1
perinuclear region of cytoplasm 3 EIF2AK2, HSP90B1, PPARG
mitochondrion 1 NR3C1
protein-containing complex 2 HSP90B1, NR3C1
intracellular membrane-bounded organelle 2 CEBPA, PPARG
Microsome membrane 1 FAAH
Secreted 1 ADIG
extracellular region 2 ADIG, HSP90B1
Single-pass membrane protein 2 ADIG, FAAH
mitochondrial matrix 1 NR3C1
transcription regulator complex 1 CEBPA
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 NR3C1
nucleolus 1 CEBPA
midbody 1 HSP90B1
Cytoplasm, perinuclear region 1 EIF2AK2
Cytoplasm, cytoskeleton 1 FAAH
Cytoplasm, cytoskeleton, spindle 1 NR3C1
focal adhesion 1 HSP90B1
spindle 1 NR3C1
collagen-containing extracellular matrix 1 HSP90B1
nuclear speck 1 NR3C1
receptor complex 1 PPARG
chromatin 4 CEBPA, CEBPB, NR3C1, PPARG
Chromosome 1 NR3C1
cytoskeleton 1 FAAH
condensed chromosome, centromeric region 1 CEBPB
organelle membrane 1 FAAH
Endomembrane system 1 FAAH
Lipid droplet 1 ADIG
Nucleus, nucleoplasm 1 NR3C1
Melanosome 1 HSP90B1
sperm plasma membrane 1 HSP90B1
endoplasmic reticulum lumen 1 HSP90B1
nuclear matrix 1 CEBPB
Sarcoplasmic reticulum lumen 1 HSP90B1
[Isoform Alpha]: Cytoplasm 1 NR3C1
endocytic vesicle lumen 1 HSP90B1
ribosome 1 EIF2AK2
[Isoform Beta]: Nucleus 1 NR3C1
[Isoform Alpha-B]: Nucleus 1 NR3C1
endoplasmic reticulum chaperone complex 1 HSP90B1
C/EBP complex 2 CEBPA, CEBPB
CHOP-C/EBP complex 2 CEBPA, CEBPB
[Isoform 4]: Nucleus, nucleolus 1 CEBPA


文献列表

  • Dahae Lee, Ji-Young Kim, Yutong Qi, Sangsu Park, Hye Lim Lee, Noriko Yamabe, Hocheol Kim, Dae Sik Jang, Ki Sung Kang. Phytochemicals from the flowers of Prunus persica (L.) Batsch: Anti-adipogenic effect of mandelamide on 3T3-L1 preadipocytes. Bioorganic & medicinal chemistry letters. 2021 10; 49(?):128326. doi: 10.1016/j.bmcl.2021.128326. [PMID: 34403725]
  • Clemens Lamberth, Hans-Joachim Kempf, Miroslav Kriz. Synthesis and fungicidal activity of N-2-(3-methoxy-4-propargyloxy) phenethyl amides. Part 3: stretched and heterocyclic mandelamide oomyceticides. Pest management science. 2007 Jan; 63(1):57-62. doi: 10.1002/ps.1308. [PMID: 17078013]
  • Clemens Lamberth, Fredrik Cederbaum, Andre Jeanguenat, Hans-Joachim Kempf, Martin Zeller, Ronald Zeun. Synthesis and fungicidal activity of N-2-(3-methoxy-4-propargyloxy)phenethyl amides. Part II: anti-oomycetic mandelamides. Pest management science. 2006 May; 62(5):446-51. doi: 10.1002/ps.1188. [PMID: 16550505]