TCE epoxide (BioDeep_00001872706)

Main id: BioDeep_00000008517

 


代谢物信息卡片


Trichloroethylene epoxide

化学式: C2HCl3O (145.9093)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1(C(O1)(Cl)Cl)Cl
InChI: InChI=1S/C2HCl3O/c3-1-2(4,5)6-1/h1H

描述信息

同义名列表

4 个代谢物同义名

Trichloroethylene epoxide; Trichloroepoxyethane; TCE epoxide; TCE epoxide



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 ALB, ANXA5, DAO, G6PD, POMC, RYR1
Peripheral membrane protein 5 ANXA5, CYP1B1, DAO, G6PD, HSD17B6
Endoplasmic reticulum membrane 1 CYP1B1
Nucleus 1 ALB
cytosol 4 ALB, ANXA5, DAO, G6PD
centrosome 1 ALB
Cell membrane 1 DAO
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 1 RYR1
cell cortex 1 RYR1
Golgi apparatus 1 ALB
Golgi membrane 1 INS
sarcolemma 2 ANXA5, RYR1
smooth endoplasmic reticulum 1 RYR1
Cytoplasm, cytosol 2 DAO, G6PD
plasma membrane 2 DAO, RYR1
presynaptic active zone 1 DAO
Membrane 4 ANXA5, CYP1B1, G6PD, RYR1
extracellular exosome 5 ALB, ANXA5, DAO, G6PD, RYR1
Lumenal side 1 HSD17B6
endoplasmic reticulum 2 ALB, HSD17B6
extracellular space 4 ALB, DAO, INS, POMC
bicellular tight junction 1 DAO
mitochondrion 1 CYP1B1
protein-containing complex 1 ALB
intracellular membrane-bounded organelle 3 CYP1B1, G6PD, HSD17B6
Microsome membrane 2 CYP1B1, HSD17B6
Secreted 4 ALB, DAO, INS, POMC
extracellular region 5 ALB, ANXA5, DAO, INS, POMC
cytoplasmic side of plasma membrane 1 G6PD
Extracellular side 1 DAO
anchoring junction 1 ALB
centriolar satellite 1 G6PD
external side of plasma membrane 1 ANXA5
Z disc 1 RYR1
focal adhesion 1 ANXA5
Peroxisome 1 DAO
sarcoplasmic reticulum 1 RYR1
Peroxisome matrix 1 DAO
peroxisomal matrix 1 DAO
collagen-containing extracellular matrix 1 ANXA5
secretory granule 1 POMC
Zymogen granule membrane 1 ANXA5
ciliary basal body 1 ALB
cell projection 1 DAO
centriole 1 ALB
Secreted, extracellular space 1 DAO
spindle pole 1 ALB
blood microparticle 1 ALB
organelle membrane 1 RYR1
endosome lumen 1 INS
I band 1 RYR1
secretory granule lumen 2 INS, POMC
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 ALB, INS
platelet alpha granule lumen 1 ALB
specific granule lumen 1 DAO
transport vesicle 1 INS
Sarcoplasmic reticulum membrane 1 RYR1
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
vesicle membrane 1 ANXA5
calcium channel complex 1 RYR1
junctional sarcoplasmic reticulum membrane 1 RYR1
terminal cisterna 1 RYR1
endothelial microparticle 1 ANXA5
ryanodine receptor complex 1 RYR1
ciliary transition fiber 1 ALB


文献列表

  • Glinda S Cooper, Susan L Makris, Paul J Nietert, Jennifer Jinot. Evidence of autoimmune-related effects of trichloroethylene exposure from studies in mice and humans. Environmental health perspectives. 2009 May; 117(5):696-702. doi: 10.1289/ehp.11782. [PMID: 19479009]
  • Weihsueh A Chiu, Miles S Okino, John C Lipscomb, Marina V Evans. Issues in the pharmacokinetics of trichloroethylene and its metabolites. Environmental health perspectives. 2006 Sep; 114(9):1450-6. doi: 10.1289/ehp.8691. [PMID: 16966104]
  • Tadao Yoshioka, Joel A Krauser, F Peter Guengerich. Microsomal oxidation of tribromoethylene and reactions of tribromoethylene oxide. Chemical research in toxicology. 2002 Nov; 15(11):1414-20. doi: 10.1021/tx020047t. [PMID: 12437332]
  • Tadao Yoshioka, Joel A Krauser, F Peter Guengerich. Tetrachloroethylene oxide: hydrolytic products and reactions with phosphate and lysine. Chemical research in toxicology. 2002 Aug; 15(8):1096-105. doi: 10.1021/tx020028j. [PMID: 12184794]
  • H Cai, F P Guengerich. Acylation of protein lysines by trichloroethylene oxide. Chemical research in toxicology. 2000 May; 13(5):327-35. doi: 10.1021/tx000003p. [PMID: 10813648]