metyrapone (BioDeep_00001867988)
Main id: BioDeep_00000002569
代谢物信息卡片
metyrapone
化学式: C14H14N2O (226.1106)
中文名称: 美替拉酮, 甲吡酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)(C1=CN=CC=C1)C(=O)C2=CN=CC=C2
InChI: InChI=1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3
描述信息
V - Various > V04 - Diagnostic agents > V04C - Other diagnostic agents > V04CD - Tests for pituitary function
D009676 - Noxae > D000963 - Antimetabolites
D004791 - Enzyme Inhibitors
C471 - Enzyme Inhibitor
同义名列表
3 个代谢物同义名
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:44241
- KEGG: C07205
- KEGGdrug: D70339
- KEGGdrug: D00410
- PubChem: 4174
- DrugBank: DB01011
- ChEMBL: CHEMBL934
- MeSH: Metyrapone
- CAS: 54-36-4
- PubChem: 9414
- PDB-CCD: MYT
- NIKKAJI: J1.369B
- RefMet: Metyrapone
- KNApSAcK: 44241
分类词条
相关代谢途径
Reactome(0)
BioCyc(5)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sarah J Young, Giulia S Rossi, Nicholas J Bernier, Patricia A Wright. Cortisol enhances aerobic metabolism and locomotor performance during the transition to land in an amphibious fish.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.
2024 Feb; 288(?):111558. doi:
10.1016/j.cbpa.2023.111558. [PMID: 38043639] - Abigail L Tice, Joseph A Laudato, Michael L Rossetti, Christopher A Wolff, Karyn A Esser, Choogon Lee, Charles H Lang, Cynthia Vied, Bradley S Gordon, Jennifer L Steiner. Binge alcohol disrupts skeletal muscle core molecular clock independent of glucocorticoids.
American journal of physiology. Endocrinology and metabolism.
2021 11; 321(5):E606-E620. doi:
10.1152/ajpendo.00187.2021. [PMID: 34541876] - Frederic Castinetti, Lynnette K Nieman, Martin Reincke, John Newell-Price. Approach to the Patient Treated with Steroidogenesis Inhibitors.
The Journal of clinical endocrinology and metabolism.
2021 06; 106(7):2114-2123. doi:
10.1210/clinem/dgab122. [PMID: 33675650] - Akiko Yuno, Yoshiyuki Kenmotsu, Yuka Takahashi, Hiroshi Nomoto, Hiraku Kameda, Kyu Yong Cho, Akinobu Nakamura, Yu Yamashita, Junichi Nakamura, Sho Nakakubo, Keisuke Kamada, Masaru Suzuki, Hirokazu Sugino, Naoko Inoshita, Satoshi Konno, Hideaki Miyoshi, Tatsuya Atsumi, Yutaka Sawamura, Akira Shimatsu. Successful management of a patient with active Cushing's disease complicated with coronavirus disease 2019 (COVID-19) pneumonia.
Endocrine journal.
2021 Apr; 68(4):477-484. doi:
10.1507/endocrj.ej20-0613. [PMID: 33361650] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - M Bencze, A Vavřínová, J Zicha, M Behuliak. Pharmacological suppression of endogenous glucocorticoid synthesis attenuated blood pressure and heart rate response to acute restraint in Wistar rats.
Physiological research.
2020 07; 69(3):415-426. doi:
10.33549/physiolres.934432. [PMID: 32469228] - John Newell-Price, Lynnette K Nieman, Martin Reincke, Antoine Tabarin. ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of Cushing's syndrome.
European journal of endocrinology.
2020 Jul; 183(1):G1-G7. doi:
10.1530/eje-20-0352. [PMID: 32380475] - Adam C Kulp, Brett M Lowden, Sachi Chaudhari, Cassidy A Ridley, James C Krzoska, David F Barnard, Devanshi M Mehta, John D Johnson. Sensitized corticosterone responses do not mediate the enhanced fear memories in chronically stressed rats.
Behavioural brain research.
2020 03; 382(?):112480. doi:
10.1016/j.bbr.2020.112480. [PMID: 31953122] - Clare L M Kennedy, Sylvia D Carter, Karen R Mifsud, Johannes M H M Reul. Unexpected effects of metyrapone on corticosteroid receptor interaction with the genome and subsequent gene transcription in the hippocampus of male rats.
Journal of neuroendocrinology.
2020 02; 32(2):e12820. doi:
10.1111/jne.12820. [PMID: 31820828] - Federica Beretta, Francesca Dassie, Matteo Parolin, Federico Boscari, Mattia Barbot, Luca Busetto, Roberto Mioni, Eugenio De Carlo, Carla Scaroni, Francesco Fallo, Roberto Vettor, Pietro Maffei. Practical Considerations for the Management of Cushing's Disease and COVID-19: A Case Report.
Frontiers in endocrinology.
2020; 11(?):554. doi:
10.3389/fendo.2020.00554. [PMID: 33071957] - Damian J Ralser, Brigitte Strizek, Patrick Kupczyk, Birgit Stoffel-Wagner, Julia Altengarten, Andreas Müller, Joachim Woelfle, Ulrich Gembruch, Dietrich Klingmueller, Waltraut M Merz, Anke Paschkowiak-Christes. Obstetric and Neonatal Outcome of Pregnancy in Carney Complex: A Case Report.
Frontiers in endocrinology.
2020; 11(?):296. doi:
10.3389/fendo.2020.00296. [PMID: 32457700] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Errol M Thomson, Alain Filiatreault, Josée Guénette. Stress hormones as potential mediators of air pollutant effects on the brain: Rapid induction of glucocorticoid-responsive genes.
Environmental research.
2019 11; 178(?):108717. doi:
10.1016/j.envres.2019.108717. [PMID: 31520820] - Taiki Okumura, Shohei Takayama, Shin-Ichi Nishio, Takahiro Miyakoshi, Takuro Noguchi, Takashi Kobayashi, Toshirou Fukushima, Nodoka Sekiguchi, Toshiaki Otsuki, Mitsuhisa Komatsu, Tomonobu Koizumi. ACTH-producing thymic neuroendocrine tumor initially presenting as psychosis: A case report and literature review.
Thoracic cancer.
2019 07; 10(7):1648-1653. doi:
10.1111/1759-7714.13099. [PMID: 31187563] - Shu-Fang Wang, Xi-Hua Chen, Bin He, De-Dong Yin, Hai-Jun Gao, Hao-Qi Zhao, Nan Nan, Shi-Ge Guo, Jian-Bing Liu, Bin Wu, Xiang-Bo Xu. Acute restraint stress triggers progesterone withdrawal and endometrial breakdown and shedding through corticosterone stimulation in mouse menstrual-like model.
Reproduction (Cambridge, England).
2019 02; 157(2):149-161. doi:
10.1530/rep-18-0163. [PMID: 30601756] - Marius Vögelin, Richard Cathomas, Niklaus Kamber, Thomas Fehr. Hypokalaemic metabolic alkalosis, hypertension and diabetes: what is the link.
BMJ case reports.
2019 Jan; 12(1):. doi:
10.1136/bcr-2018-227068. [PMID: 30661045] - Manabu Kadoya, Masafumi Kurajoh, Akio Miyoshi, Takuhito Shoji, Tomonori Terada, Yuji Nakamoto, Yoshitane Tsukamoto, Yuji Moriwaki, Seiichi Hirota, Hidenori Koyama. Ectopic adrenocorticotropic hormone syndrome associated with olfactory neuroblastoma: acquirement of adrenocorticotropic hormone expression during disease course as shown by serial immunohistochemistry examinations.
The Journal of international medical research.
2018 Nov; 46(11):4760-4768. doi:
10.1177/0300060517754026. [PMID: 30392451] - Roseli Soncini, Joseana Vieira, Ana Carolina Ramos Lopes, Silvia Graciela Ruginsk, Erika K Incerpi, Angel Roberto Barchuk. Glucocorticoid receptor gene expression in a CLP-induced ARDS-like rat model treated with dexamethasone and metyrapone.
Molecular and cellular endocrinology.
2018 10; 474(?):151-157. doi:
10.1016/j.mce.2018.03.001. [PMID: 29522858] - Minako Inoue, Ken Okamura, Chie Kitaoka, Fumio Kinoshita, Ryo Namitome, Udai Nakamura, Masaki Shiota, Kenichi Goto, Toshio Ohtsubo, Kiyoshi Matsumura, Yoshinao Oda, Masatoshi Eto, Takanari Kitazono. Metyrapone-responsive ectopic ACTH-secreting pheochromocytoma with a vicious cycle via a glucocorticoid-driven positive-feedback mechanism.
Endocrine journal.
2018 Jul; 65(7):755-767. doi:
10.1507/endocrj.ej18-0025. [PMID: 29760304] - Mélanie Claps, Sara Cerri, Salvatore Grisanti, Barbara Lazzari, Vittorio Ferrari, Elisa Roca, Paola Perotti, Massimo Terzolo, Sandra Sigala, Alfredo Berruti. Adding metyrapone to chemotherapy plus mitotane for Cushing's syndrome due to advanced adrenocortical carcinoma.
Endocrine.
2018 07; 61(1):169-172. doi:
10.1007/s12020-017-1428-9. [PMID: 29019062] - Hideyuki Iwayama, Sho Hirase, Yuka Nomura, Tatsuo Ito, Hiroyuki Morita, Kazuo Otake, Akihisa Okumura, Junko Takagi. Spontaneous adrenocorticotropic hormone (ACTH) normalisation due to tumour regression induced by metyrapone in a patient with ectopic ACTH syndrome: case report and literature review.
BMC endocrine disorders.
2018 Mar; 18(1):19. doi:
10.1186/s12902-018-0246-2. [PMID: 29587720] - Juliette Emmerich, Chris J van Koppen, Jens L Burkhart, Roger T Engeli, Qingzhong Hu, Alex Odermatt, Rolf W Hartmann. Accelerated skin wound healing by selective 11β-Hydroxylase (CYP11B1) inhibitors.
European journal of medicinal chemistry.
2018 Jan; 143(?):591-597. doi:
10.1016/j.ejmech.2017.11.018. [PMID: 29207342] - Miguel Debono, Robert F Harrison, Rita Chadarevian, Carole Gueroult, Jean-Louis Abitbol, John Newell-Price. Resetting the Abnormal Circadian Cortisol Rhythm in Adrenal Incidentaloma Patients With Mild Autonomous Cortisol Secretion.
The Journal of clinical endocrinology and metabolism.
2017 09; 102(9):3461-3469. doi:
10.1210/jc.2017-00823. [PMID: 28911138] - Malik Asif Humayun, Tanya Hart, Tristan Richardson. Cyclical Cushing's: how best to catch the ups and downs.
BMJ case reports.
2017 Jul; 2017(?):. doi:
10.1136/bcr-2016-218451. [PMID: 28705797] - Juliette Emmerich, Chris J van Koppen, Jens L Burkhart, Qingzhong Hu, Lorenz Siebenbürger, Carsten Boerger, Claudia Scheuer, Matthias W Laschke, Michael D Menger, Rolf W Hartmann. Lead Optimization Generates CYP11B1 Inhibitors of Pyridylmethyl Isoxazole Type with Improved Pharmacological Profile for the Treatment of Cushing's Disease.
Journal of medicinal chemistry.
2017 06; 60(12):5086-5098. doi:
10.1021/acs.jmedchem.7b00437. [PMID: 28570067] - Wojciech Zieleniewski, Renata Michalak. A successful case of pregnancy in a woman with ACTH-independent Cushing's syndrome treated with ketoconazole and metyrapone.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.
2017 May; 33(5):349-352. doi:
10.1080/09513590.2017.1290070. [PMID: 28277127] - Courtney M Keller, Kelly N Breaux, Nicholas E Goeders. Effects of the combination of metyrapone and oxazepam on cocaine-induced increases in corticosterone in the medial prefrontal cortex and nucleus accumbens.
Psychoneuroendocrinology.
2017 03; 77(?):75-83. doi:
10.1016/j.psyneuen.2016.12.004. [PMID: 28024272] - B Ponchon, X Zhao, S Ollier, P Lacasse. Relationship between glucocorticoids and prolactin during mammary gland stimulation in dairy cows.
Journal of dairy science.
2017 Feb; 100(2):1521-1534. doi:
10.3168/jds.2016-11490. [PMID: 28012629] - Margaret O Murphy, Joseph B Herald, Caleb T Wills, Stanley G Unfried, Dianne M Cohn, Analia S Loria. Postnatal treatment with metyrapone attenuates the effects of diet-induced obesity in female rats exposed to early-life stress.
American journal of physiology. Endocrinology and metabolism.
2017 02; 312(2):E98-E108. doi:
10.1152/ajpendo.00308.2016. [PMID: 27965205] - Hideyuki Murata, Toshiyuki Higuchi, Masaki Otagiri. Oral pharmacokinetics and in-vitro metabolism of metyrapone in male rats.
The Journal of pharmacy and pharmacology.
2016 Aug; 68(8):970-9. doi:
10.1111/jphp.12560. [PMID: 27265478] - Errol M Thomson, Shinjini Pal, Josée Guénette, Michael G Wade, Ella Atlas, Alison C Holloway, Andrew Williams, Renaud Vincent. Ozone Inhalation Provokes Glucocorticoid-Dependent and -Independent Effects on Inflammatory and Metabolic Pathways.
Toxicological sciences : an official journal of the Society of Toxicology.
2016 07; 152(1):17-28. doi:
10.1093/toxsci/kfw061. [PMID: 27037194] - Piray Atsak, Friederike M Guenzel, Deniz Kantar-Gok, Ioannis Zalachoras, Piraye Yargicoglu, Onno C Meijer, Gina L Quirarte, Oliver T Wolf, Lars Schwabe, Benno Roozendaal. Glucocorticoids mediate stress-induced impairment of retrieval of stimulus-response memory.
Psychoneuroendocrinology.
2016 May; 67(?):207-15. doi:
10.1016/j.psyneuen.2016.02.006. [PMID: 26923851] - Krystallenia I Alexandraki, Ashley B Grossman. Therapeutic Strategies for the Treatment of Severe Cushing's Syndrome.
Drugs.
2016 Mar; 76(4):447-58. doi:
10.1007/s40265-016-0539-6. [PMID: 26833215] - Antonio Stigliano, Vincenzo Toscano. [Indications and future perspectives in the pharmacological treatment of hypercortisolism].
Recenti progressi in medicina.
2016 Mar; 107(3):143-8. doi:
10.1701/2182.23606. [PMID: 27030224] - Eleni Daniel, Simon Aylwin, Omar Mustafa, Steve Ball, Atif Munir, Kristien Boelaert, Vasileios Chortis, Daniel J Cuthbertson, Christina Daousi, Surya P Rajeev, Julian Davis, Kelly Cheer, William Drake, Kirun Gunganah, Ashley Grossman, Mark Gurnell, Andrew S Powlson, Niki Karavitaki, Isabel Huguet, Tara Kearney, Kumar Mohit, Karim Meeran, Neil Hill, Aled Rees, Andrew J Lansdown, Peter J Trainer, Anna-Elisabeth H Minder, John Newell-Price. Effectiveness of Metyrapone in Treating Cushing's Syndrome: A Retrospective Multicenter Study in 195 Patients.
The Journal of clinical endocrinology and metabolism.
2015 Nov; 100(11):4146-54. doi:
10.1210/jc.2015-2616. [PMID: 26353009] - Christopher D Schmoutz, Glenn F Guerin, Scott P Runyon, Suraj Dhungana, Nicholas E Goeders. A therapeutic combination of metyrapone and oxazepam increases brain levels of GABA-active neurosteroids and decreases cocaine self-administration in male rats.
Behavioural brain research.
2015 Sep; 291(?):108-111. doi:
10.1016/j.bbr.2015.05.019. [PMID: 26003946] - Marta Librán-Pérez, Cristina Velasco, Cristina Otero-Rodiño, Marcos A López-Patiño, Jesús M Míguez, José L Soengas. Metabolic response in liver and Brockmann bodies of rainbow trout to inhibition of lipolysis; possible involvement of the hypothalamus-pituitary-interrenal (HPI) axis.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology.
2015 May; 185(4):413-23. doi:
10.1007/s00360-015-0894-8. [PMID: 25666862] - Jean-Benoît Corcuff, Jacques Young, Pauline Masquefa-Giraud, Philippe Chanson, Eric Baudin, Antoine Tabarin. Rapid control of severe neoplastic hypercortisolism with metyrapone and ketoconazole.
European journal of endocrinology.
2015 Apr; 172(4):473-81. doi:
10.1530/eje-14-0913. [PMID: 25624013] - Reka Natarajan, Nicole A Northrop, Bryan K Yamamoto. Protracted effects of chronic stress on serotonin-dependent thermoregulation.
Stress (Amsterdam, Netherlands).
2015; 18(6):668-76. doi:
10.3109/10253890.2015.1087502. [PMID: 26414686] - Donald R Gehlert, Janice Shaw. 5-Hydroxytryptamine 1A (5HT1A) receptors mediate increases in plasma glucose independent of corticosterone.
European journal of pharmacology.
2014 Dec; 745(?):91-7. doi:
10.1016/j.ejphar.2014.10.010. [PMID: 25446927] - M A Miazina, T R Bagaeva, L P Filaretova. [Metyrapone effect on gastroprotective action of corticotropin-releasing factor administered centrally against indomethacin-induced gastric injury].
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova.
2014 Dec; 100(12):1421-30. doi:
. [PMID: 25936181] - Weixing Zhu, Qingzhong Hu, Nina Hanke, Chris J van Koppen, Rolf W Hartmann. Potent 11β-hydroxylase inhibitors with inverse metabolic stability in human plasma and hepatic S9 fractions to promote wound healing.
Journal of medicinal chemistry.
2014 Sep; 57(18):7811-7. doi:
10.1021/jm501004t. [PMID: 25176013] - Christopher D Schmoutz, Glenn F Guerin, Nicholas E Goeders. Role of GABA-active neurosteroids in the efficacy of metyrapone against cocaine addiction.
Behavioural brain research.
2014 Sep; 271(?):269-76. doi:
10.1016/j.bbr.2014.06.032. [PMID: 24959859] - Glenn F Guerin, Christopher D Schmoutz, Nicholas E Goeders. The extra-adrenal effects of metyrapone and oxazepam on ongoing cocaine self-administration.
Brain research.
2014 Aug; 1575(?):45-54. doi:
10.1016/j.brainres.2014.05.039. [PMID: 24887642] - Georgina M Russell, Claire Durant, Alia Ataya, Chrysoula Papastathi, Ragini Bhake, Wolfram Woltersdorf, Stafford Lightman. Subcutaneous pulsatile glucocorticoid replacement therapy.
Clinical endocrinology.
2014 Aug; 81(2):289-93. doi:
10.1111/cen.12470. [PMID: 24735400] - Robert Lim, Alexey V Fedulov, Lester Kobzik. Maternal stress during pregnancy increases neonatal allergy susceptibility: role of glucocorticoids.
American journal of physiology. Lung cellular and molecular physiology.
2014 Jul; 307(2):L141-8. doi:
10.1152/ajplung.00250.2013. [PMID: 24838749] - Qingzhong Hu, Lina Yin, Rolf W Hartmann. Aldosterone synthase inhibitors as promising treatments for mineralocorticoid dependent cardiovascular and renal diseases.
Journal of medicinal chemistry.
2014 Jun; 57(12):5011-22. doi:
10.1021/jm401430e. [PMID: 24422519] - Deborah I Lutterschmidt, Ashley R Maine. Sex or candy? Neuroendocrine regulation of the seasonal transition from courtship to feeding behavior in male red-sided garter snakes (Thamnophis sirtalis parietalis).
Hormones and behavior.
2014 Jun; 66(1):120-34. doi:
10.1016/j.yhbeh.2014.01.011. [PMID: 24508620] - Ambarisha Chabbi, C B Ganesh. Glucocorticoid synthesis inhibitor metyrapone blocks stress-induced suppression along luteinizing hormone secreting cells–ovary axis in the fish Oreochromis mossambicus.
Journal of experimental zoology. Part A, Ecological genetics and physiology.
2014 Mar; 321(3):125-34. doi:
10.1002/jez.1842. [PMID: 24639434] - M V Fogaça, F M C V Reis, A C Campos, F S Guimarães. Effects of intra-prelimbic prefrontal cortex injection of cannabidiol on anxiety-like behavior: involvement of 5HT1A receptors and previous stressful experience.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology.
2014 Mar; 24(3):410-9. doi:
10.1016/j.euroneuro.2013.10.012. [PMID: 24321837] - O F C van den Bosch, A M E Stades, P M J Zelissen. Increased long-term remission after adequate medical cortisol suppression therapy as presurgical treatment in Cushing's disease.
Clinical endocrinology.
2014 Feb; 80(2):184-90. doi:
10.1111/cen.12286. [PMID: 23841642] - Daniela Masid-de-Brito, Pedro Xavier-Elsas, Ricardo Alves Luz, Túlio Queto, Cássio Luiz Coutinho Almeida da Silva, Rodrigo Soares Lopes, Bruno Marques Vieira, Maria Ignez Capella Gaspar-Elsas. Essential roles of endogenous glucocorticoids and TNF/TNFR1 in promoting bone-marrow eosinopoiesis in ovalbumin-sensitized, airway-challenged mice.
Life sciences.
2014 Jan; 94(1):74-82. doi:
10.1016/j.lfs.2013.11.006. [PMID: 24239638] - Marta Librán-Pérez, Cristina Velasco, Marcos A López-Patiño, Jesús M Míguez, José L Soengas. Counter-regulatory response to a fall in circulating fatty acid levels in rainbow trout. Possible involvement of the hypothalamus-pituitary-interrenal axis.
PloS one.
2014; 9(11):e113291. doi:
10.1371/journal.pone.0113291. [PMID: 25405879] - Nicholas E Goeders, Glenn F Guerin, Christopher D Schmoutz. The combination of metyrapone and oxazepam for the treatment of cocaine and other drug addictions.
Advances in pharmacology (San Diego, Calif.).
2014; 69(?):419-79. doi:
10.1016/b978-0-12-420118-7.00011-1. [PMID: 24484984] - Courtney M Keller, Elyse M Cornett, Glenn F Guerin, Nicholas E Goeders. Combinations of oxazepam and metyrapone attenuate cocaine and methamphetamine cue reactivity.
Drug and alcohol dependence.
2013 Dec; 133(2):405-12. doi:
10.1016/j.drugalcdep.2013.06.025. [PMID: 23896309] - Pablo Abellán Galiana, Carmen Fajardo Montañana, Pedro Antonio Riesgo Suárez, José Gómez Vela, Carlos Meseguer Escrivá, Vicente Rovira Lillo. [Predictors of long-term remission after transsphenoidal surgery in Cushing's disease].
Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion.
2013 Oct; 60(8):475-82. doi:
10.1016/j.endonu.2012.09.009. [PMID: 23266144] - Juliette Emmerich, Qingzhong Hu, Nina Hanke, Rolf W Hartmann. Cushing's syndrome: development of highly potent and selective CYP11B1 inhibitors of the (pyridylmethyl)pyridine type.
Journal of medicinal chemistry.
2013 Aug; 56(15):6022-32. doi:
10.1021/jm400240r. [PMID: 23869452] - Radosław Swiercz, Piotr Lutz, Sławomir Gralewicz, Zofia Grzelińska, Joanna Piasecka-Zelga, Wojciech Wąsowicz. Partial protection from organophosphate-induced cholinesterase inhibition by metyrapone treatment.
International journal of occupational medicine and environmental health.
2013 Aug; 26(4):636-46. doi:
10.2478/s13382-013-0131-1. [PMID: 24052154] - André L Takatsu-Coleman, Camilla L Patti, Karina A Zanin, Adriano Zager, Rita C Carvalho, Aline R Borçoi, Liliane M B Ceccon, Laís F Berro, Sergio Tufik, Monica L Andersen, Roberto Frussa-Filho. Short-term social isolation induces depressive-like behaviour and reinstates the retrieval of an aversive task: mood-congruent memory in male mice?.
Journal of psychiatry & neuroscience : JPN.
2013 Jul; 38(4):259-68. doi:
10.1503/jpn.120050. [PMID: 23182303] - Patrizia Campolongo, Maria Morena, Sergio Scaccianoce, Viviana Trezza, Flavia Chiarotti, Gustav Schelling, Vincenzo Cuomo, Benno Roozendaal. Novelty-induced emotional arousal modulates cannabinoid effects on recognition memory and adrenocortical activity.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2013 Jun; 38(7):1276-86. doi:
10.1038/npp.2013.26. [PMID: 23340520] - Mano Aliczki, Dora Zelena, Eva Mikics, Zoltan K Varga, Otto Pinter, Nikoletta Venczkone Bakos, Janos Varga, Jozsef Haller. Monoacylglycerol lipase inhibition-induced changes in plasma corticosterone levels, anxiety and locomotor activity in male CD1 mice.
Hormones and behavior.
2013 May; 63(5):752-8. doi:
10.1016/j.yhbeh.2013.03.017. [PMID: 23578952] - Wei How Lim, David J Torpy, William S Jeffries. The medical management of Cushing's syndrome during pregnancy.
European journal of obstetrics, gynecology, and reproductive biology.
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Neurobiology of disease.
2012 Jul; 47(1):29-37. doi:
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Hormones and behavior.
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Clinical endocrinology.
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Pharmacology, biochemistry, and behavior.
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The Journal of steroid biochemistry and molecular biology.
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Behavioural brain research.
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Lab animal.
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Archives of medical science : AMS.
2012 Feb; 8(1):22-9. doi:
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The Journal of clinical endocrinology and metabolism.
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The Journal of experimental biology.
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The Journal of reproduction and development.
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The Journal of clinical endocrinology and metabolism.
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Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
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Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.
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The Journal of clinical endocrinology and metabolism.
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Annals of clinical biochemistry.
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Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.
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Archives of pharmacal research.
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BMC veterinary research.
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Brain research bulletin.
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Neuropharmacology.
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Behavioural brain research.
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The Journal of endocrinology.
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In vitro cellular & developmental biology. Animal.
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American journal of hypertension.
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Journal of pediatric endocrinology & metabolism : JPEM.
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