Propulsid (BioDeep_00001867960)
Main id: BioDeep_00000002711
代谢物信息卡片
Propulsid
化学式: C23H29ClFN3O4 (465.1831)
中文名称: 西沙必利
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: ClC1=C(N)C=C(OC)C(C(N[C@H]2[C@@H](OC)CN(CCCOC3=CC=C(F)C=C3)CC2)=O)=C1
InChI: InChI=1S/C23H29ClFN3O4/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29)
描述信息
A - Alimentary tract and metabolism > A03 - Drugs for functional gastrointestinal disorders > A03F - Propulsives > A03FA - Propulsives
D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists
D005765 - Gastrointestinal Agents > D000897 - Anti-Ulcer Agents
Cisapride (R 51619) is an orally active 5-HT4 receptor agonist with an EC50 value of 140 nM. Cisapride is a hERG blocker with an IC50 value of 9.4 nM. Cisapride is a gastroprokinetic agent that stimulates gastrointestinal motor activity[1][2][3][4].
同义名列表
5 个代谢物同义名
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:95129
- KEGG: C06910
- KEGGdrug: D00274
- PubChem: 2769
- ChEMBL: CHEMBL1729
- MeSH: Cisapride
- CAS: 104860-73-3
- CAS: 81098-60-4
- ChEBI: CHEBI:3720
- PubChem: 9127
- NIKKAJI: J299.805J
- medchemexpress: HY-14149
- KNApSAcK: 3720
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Erica R Feldman, Bhupinder Singh, Noah G Mishkin, Erica R Lachenauer, Manuel Martin-Flores, Erin K Daugherity. Effects of Cisapride, Buprenorphine, and Their Combination on Gastrointestinal Transit in New Zealand White Rabbits.
Journal of the American Association for Laboratory Animal Science : JAALAS.
2021 03; 60(2):221-228. doi:
10.30802/aalas-jaalas-20-000064. [PMID: 33632373] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Sonia Goineau, Vincent Castagné. Electrophysiological characteristics and pharmacological sensitivity of two lines of human induced pluripotent stem cell derived cardiomyocytes coming from two different suppliers.
Journal of pharmacological and toxicological methods.
2018 Mar; 90(?):58-66. doi:
10.1016/j.vascn.2017.12.003. [PMID: 29274391] - Jiesheng Kang, Yongyi Luo, Michelle Searles, David Rampe. Observations on conducting whole-cell patch clamping of the hERG cardiac K+ channel in pure human serum.
Journal of applied toxicology : JAT.
2017 04; 37(4):445-453. doi:
10.1002/jat.3377. [PMID: 27553911] - Dan-Yan Li, Yun-Kai Dai, Yun-Zhan Zhang, Meng-Xin Huang, Ru-Liu Li, Jia Ou-Yang, Wei-Jing Chen, Ling Hu. Systematic review and meta-analysis of traditional Chinese medicine in the treatment of constipation-predominant irritable bowel syndrome.
PloS one.
2017; 12(12):e0189491. doi:
10.1371/journal.pone.0189491. [PMID: 29253850] - Yong Ai, Yang Hu, Fenghua Kang, Yisheng Lai, Yanju Jia, Zhangjian Huang, Sixun Peng, Hui Ji, Jide Tian, Yihua Zhang. Synthesis and Biological Evaluation of Novel Olean-28,13β-lactams as Potential Antiprostate Cancer Agents.
Journal of medicinal chemistry.
2015 Jun; 58(11):4506-20. doi:
10.1021/jm5020023. [PMID: 25992974] - S M Ghoreishi, M Nouri, A Rasooli, M Ghorbanpour, M R Mokhber-Dezfouli, P D Constable. Effect of orally administered cisapride, bethanechol, and erythromycin on the apparent efficiency of colostral IgG absorption in neonatal Holstein-Friesian calves.
Journal of veterinary internal medicine.
2015 Mar; 29(2):714-20. doi:
10.1111/jvim.12539. [PMID: 25641234] - Lei Lan, Fang Zeng, Guan J Liu, Li Ying, Xi Wu, Mailan Liu, Fan-Rong Liang. Acupuncture for functional dyspepsia.
The Cochrane database of systematic reviews.
2014 Oct; ?(10):CD008487. doi:
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Journal of medicinal chemistry.
2014 May; 57(10):4213-38. doi:
10.1021/jm500115w. [PMID: 24786585] - Liang Guo, Luke Coyle, Rory M C Abrams, Raymond Kemper, Eric T Chiao, Kyle L Kolaja. Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model.
Toxicological sciences : an official journal of the Society of Toxicology.
2013 Dec; 136(2):581-94. doi:
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Circulation.
2013 Apr; 127(16):1677-91. doi:
10.1161/circulationaha.113.001883. [PMID: 23519760] - Vassilios Bavetsias, Simon Crumpler, Chongbo Sun, Sian Avery, Butrus Atrash, Amir Faisal, Andrew S Moore, Magda Kosmopoulou, Nathan Brown, Peter W Sheldrake, Katherine Bush, Alan Henley, Gary Box, Melanie Valenti, Alexis de Haven Brandon, Florence I Raynaud, Paul Workman, Suzanne A Eccles, Richard Bayliss, Spiros Linardopoulos, Julian Blagg. Optimization of imidazo[4,5-b]pyridine-based kinase inhibitors: identification of a dual FLT3/Aurora kinase inhibitor as an orally bioavailable preclinical development candidate for the treatment of acute myeloid leukemia.
Journal of medicinal chemistry.
2012 Oct; 55(20):8721-34. doi:
10.1021/jm300952s. [PMID: 23043539] - Zhiwu Lin, Yvonne Will. Evaluation of drugs with specific organ toxicities in organ-specific cell lines.
Toxicological sciences : an official journal of the Society of Toxicology.
2012 Mar; 126(1):114-27. doi:
10.1093/toxsci/kfr339. [PMID: 22166485] - P A Boakye, C Stenkamp-Strahm, Y Bhattarai, M D Heckman, S M Brierley, S P Pasilis, O B Balemba. 5-HT(3) and 5-HT(4) receptors contribute to the anti-motility effects of Garcinia buchananii bark extract in the guinea-pig distal colon.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
2012 Jan; 24(1):e27-40. doi:
10.1111/j.1365-2982.2011.01807.x. [PMID: 22074563] - J R Goldsmith, Christian Jobin. Think small: zebrafish as a model system of human pathology.
Journal of biomedicine & biotechnology.
2012; 2012(?):817341. doi:
10.1155/2012/817341. [PMID: 22701308] - Valerie Freiche, Doreen Houston, Heather Weese, Michelle Evason, Géraldine Deswarte, Gérald Ettinger, Yannick Soulard, Vincent Biourge, Alexander J German. Uncontrolled study assessing the impact of a psyllium-enriched extruded dry diet on faecal consistency in cats with constipation.
Journal of feline medicine and surgery.
2011 Dec; 13(12):903-11. doi:
10.1016/j.jfms.2011.07.008. [PMID: 21944542] - Xin-Jian Qiu, Xi Huang, Ze-Qi Chen, Ping Ren, Wei Huang, Feng Qin, Si-Hang Hu, Jun Huang, Juan He, Zhao-Qian Liu, Hong-Hao Zhou. Pharmacokinetic study of the prokinetic compounds meranzin hydrate and ferulic acid following oral administration of Chaihu-Shugan-San to patients with functional dyspepsia.
Journal of ethnopharmacology.
2011 Sep; 137(1):205-13. doi:
10.1016/j.jep.2011.05.009. [PMID: 21605652] - Y-R Jin, J Jin, X-X Piao, N G Jin. The effect of Taraxacum officinale on gastric emptying and smooth muscle motility in Rodents.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
2011 Aug; 23(8):766-e333. doi:
10.1111/j.1365-2982.2011.01704.x. [PMID: 21453412] - Sachin V Tembhurne, Dinesh M Sakarkar. Effects of Murraya koenigii leaf extract on impaired gastrointestinal motility in streptozotocin-induced diabetic rats.
Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.
2011 Aug; 9(8):913-9. doi:
10.3736/jcim20110814. [PMID: 21849153] - Hongli Wu, Zhiwei Jing, Xudong Tang, Xinyue Wang, Shengsheng Zhang, Yanan Yu, Zhong Wang, Hongxin Cao, Luqi Huang, Youhua Yu, Yongyan Wang. To compare the efficacy of two kinds of Zhizhu pills in the treatment of functional dyspepsia of spleen-deficiency and qi-stagnation syndrome: a randomized group sequential comparative trial.
BMC gastroenterology.
2011 Jul; 11(?):81. doi:
10.1186/1471-230x-11-81. [PMID: 21762493] - Yasuto Kido, Pär Matsson, Kathleen M Giacomini. Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.
Journal of medicinal chemistry.
2011 Jul; 54(13):4548-58. doi:
10.1021/jm2001629. [PMID: 21599003] - Sirima Mahattanadul, Wibool Ridtitid, Sawpheeyah Nima, Narubodee Phdoongsombut, Pranee Ratanasuwon, Srirat Kasiwong. Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats.
Journal of ethnopharmacology.
2011 Mar; 134(2):243-50. doi:
10.1016/j.jep.2010.12.004. [PMID: 21163341] - Anna M Wobus, Peter Löser. Present state and future perspectives of using pluripotent stem cells in toxicology research.
Archives of toxicology.
2011 Feb; 85(2):79-117. doi:
10.1007/s00204-010-0641-6. [PMID: 21225242] - Asma Lat, George R Thompson. Update on the optimal use of voriconazole for invasive fungal infections.
Infection and drug resistance.
2011; 4(?):43-53. doi:
10.2147/idr.s12714. [PMID: 21694908] - Offie P Soldin, Sarah H Chung, Donald R Mattison. Sex differences in drug disposition.
Journal of biomedicine & biotechnology.
2011; 2011(?):187103. doi:
10.1155/2011/187103. [PMID: 21403873] - Myung-Jae Lee, Heon-Woo Lee, Jong-Min Kang, Ji-Hyung Seo, Seong-Kun Tak, Wangseob Shim, Sung-Vin Yim, Seung Jae Hong, Kyung-Tae Lee. Application of a rapid and selective method for the simultaneous determination of carebastine and pseudoephedrine in human plasma by liquid chromatography-electrospray mass spectrometry for bioequivalence study in Korean subjects.
Biomedical chromatography : BMC.
2010 Oct; 24(10):1031-7. doi:
10.1002/bmc.1392. [PMID: 20099369] - Bodil Ohlsson, Eva Ekblad, Béla Veress, Agneta Montgomery, Sabina Janciauskiene. Antibodies against gonadotropin-releasing hormone (GnRH) and destruction of enteric neurons in 3 patients suffering from gastrointestinal dysfunction.
BMC gastroenterology.
2010 May; 10(?):48. doi:
10.1186/1471-230x-10-48. [PMID: 20487533] - Michael Margulis, Steve Sorota, Inhou Chu, Anthony Soares, Tony Priestley, Amin A Nomeir. Protein binding-dependent decreases in hERG channel blocker potency assessed by whole-cell voltage clamp in serum.
Journal of cardiovascular pharmacology.
2010 Apr; 55(4):368-76. doi:
10.1097/fjc.0b013e3181d2ce39. [PMID: 20125032] - Ching-Ling Cheng, Ya-Win Chang, Chen-Hsi Chou. HPLC-fluorescence assay for measuring mosapride in small volumes of rat plasma.
Biomedical chromatography : BMC.
2010 Mar; 24(3):281-8. doi:
10.1002/bmc.1285. [PMID: 19653243] - Biagio Di Iorio, Emanuele Cucciniello. Lanthanum carbonate is not associated with QT interval modification in hemodialysis patients.
Clinical pharmacology : advances and applications.
2010; 2(?):89-93. doi:
10.2147/cpaa.s10218. [PMID: 22291491] - Guillermo Alberto Keller, Guillermo Di Girolamo. Prokinetic agents and QT prolongation: a familiar scene with new actors.
Current drug safety.
2010 Jan; 5(1):73-8. doi:
10.2174/157488610789869166. [PMID: 20210722] - Hee-Kyung Hong, Weon-Jong Yoon, Young Ho Kim, Eun-Sook Yoo, Su-Hyun Jo. Inhibition of the human ether-a-go-go-related gene (HERG) K+ channels by Lindera erythrocarpa.
Journal of Korean medical science.
2009 Dec; 24(6):1089-98. doi:
10.3346/jkms.2009.24.6.1089. [PMID: 19949665] - Franco Maggiolo. Efavirenz: a decade of clinical experience in the treatment of HIV.
The Journal of antimicrobial chemotherapy.
2009 Nov; 64(5):910-28. doi:
10.1093/jac/dkp334. [PMID: 19767318] - Yi Liu, Xiao-Rui Zhao, Rui Wang, Gen-Quan Qiu, Mei Zhang. [Effect of Zhizhuwan on gastrointestinal peptide concentrations in plasma of diabetic gastroenteropathy with constipation patients].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2008 Dec; 33(24):2966-8. doi:
. [PMID: 19294863] - Mitsuyasu Tabo, Ryuichi Komatsu, Masaki Honda, Misae Itoh, Kazuya Kimura. Cardiovascular safety profile of MA-2029, a novel motilin receptor antagonist.
The Journal of toxicological sciences.
2008 Dec; 33(5):631-9. doi:
10.2131/jts.33.631. [PMID: 19043284] - Tae Ho Lee, Jeong June Choi, Dong Hee Kim, Seok Choi, Kang Ro Lee, Miwon Son, Mirim Jin. Gastroprokinetic effects of DA-9701, a new prokinetic agent formulated with Pharbitis Semen and Corydalis Tuber.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2008 Oct; 15(10):836-43. doi:
10.1016/j.phymed.2008.02.019. [PMID: 18490147] - Een Jeong Park, Hye Won Lee, Hye Young Ji, Hoe Yoon Kim, Mann Hyung Lee, Eun-Seok Park, Kang Choon Lee, Hye Suk Lee. Hydrophilic interaction chromatography-tandem mass spectrometry of donepezil in human plasma: application to a pharmacokinetic study of donepezil in volunteers.
Archives of pharmacal research.
2008 Sep; 31(9):1205-11. doi:
10.1007/s12272-001-1290-6. [PMID: 18806965] - Anthony A Fossa. Assessing QT prolongation in conscious dogs: validation of a beat-to-beat method.
Pharmacology & therapeutics.
2008 Aug; 119(2):133-40. doi:
10.1016/j.pharmthera.2008.02.013. [PMID: 18938261] - Mitsu Onoma, Ken-ichi Ozaki, Kenji Yogo, Makoto Monnai, Hiroyasu Muramatsu, Kenshi Kamei, Yoshiki Kawabe, Shuji Hayashi, Toshihiko Shiga, Saori Matsuo, Masami Suzuki, Zen Itoh, Satoshi Omura, Hisanori Takanashi. Mitemcinal (GM-611), an orally active motilin receptor agonist, improves delayed gastric emptying in a canine model of diabetic gastroparesis.
Clinical and experimental pharmacology & physiology.
2008 Jul; 35(7):788-96. doi:
10.1111/j.1440-1681.2008.04924.x. [PMID: 18346169] - J A M Smith, D T Beattie, D Marquess, J P Shaw, R G Vickery, P P A Humphrey. The in vitro pharmacological profile of TD-5108, a selective 5-HT(4) receptor agonist with high intrinsic activity.
Naunyn-Schmiedeberg's archives of pharmacology.
2008 Jul; 378(1):125-37. doi:
10.1007/s00210-008-0282-y. [PMID: 18415081] - Hyun Chul Lim, Young Gyun Kim, Jung Hyun Lim, Hee Sun Kim, Hyojin Park. Effect of itopride hydrochloride on the ileal and colonic motility in guinea pig in vitro.
Yonsei medical journal.
2008 Jun; 49(3):472-8. doi:
10.3349/ymj.2008.49.3.472. [PMID: 18581598] - Anthony A Fossa. Assessing QT prolongation in conscious dogs: validation of a beat-to-beat method.
Pharmacology & therapeutics.
2008 May; 118(2):231-8. doi:
10.1016/j.pharmthera.2008.02.006. [PMID: 18420278] - Hye Young Ji, Eun Jeong Park, Kang Choon Lee, Hye Suk Lee. Quantification of doxazosin in human plasma using hydrophilic interaction liquid chromatography with tandem mass spectrometry.
Journal of separation science.
2008 May; 31(9):1628-33. doi:
10.1002/jssc.200700662. [PMID: 18401863] - Zhao-hong Shi, Wen Su, Jie-mei Zhang, Jian-jun Hao, Yun-xia Feng, Zhou Chen. [Therapeutic effects of Tiaozhong Granule on esophagus mucous membrane in rats with mixed reflux esophagitis and the mechanisms].
Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.
2008 Apr; 6(4):366-71. doi:
10.3736/jcim20080408. [PMID: 18405603] - Ian N Olver. Prevention of chemotherapy-induced nausea and vomiting: focus on fosaprepitant.
Therapeutics and clinical risk management.
2008 Apr; 4(2):501-6. doi:
10.2147/tcrm.s2345. [PMID: 18728837] - Dong-sheng Wang, Shun Wang, Ling-li Kong, Wei-yan Wang, Xiao-mei Cui. [Clinical observation on abdominal electroacupuncture for treatment of poststroke constipation].
Zhongguo zhen jiu = Chinese acupuncture & moxibustion.
2008 Jan; 28(1):7-9. doi:
". [PMID: 18257178] - Jawad Kiani, Sardar Z Imam. Medicinal importance of grapefruit juice and its interaction with various drugs.
Nutrition journal.
2007 Oct; 6(?):33. doi:
10.1186/1475-2891-6-33. [PMID: 17971226] - Anna Ollerstam, Sandra A G Visser, Göran Duker, Tomas Forsberg, Anna H Persson, Lars B Nilsson, Jan-Arne Björkman, Johan Gabrielsson, Ahmad Al-Saffar. Comparison of the QT interval response during sinus and paced rhythm in conscious and anesthetized beagle dogs.
Journal of pharmacological and toxicological methods.
2007 Sep; 56(2):131-44. doi:
10.1016/j.vascn.2007.05.002. [PMID: 17689270] - Kazuya Kimura, Mitsuyasu Tabo, Misae Itoh, Keiji Mizoguchi, Atsuhiko Kato, Masami Suzuki, Zen Itoh, Satoshi Omura, Hisanori Takanashi. Preclinical electrophysiology assays of mitemcinal (GM-611), a novel prokinetic agent derived from erythromycin.
The Journal of toxicological sciences.
2007 Aug; 32(3):217-30. doi:
10.2131/jts.32.217. [PMID: 17785939] - James T Limberis, Jeff S McDermott, Heinz J Salmen, Zhi Su, Ann Mikhail, Jonathon R Green, Bryan F Cox, Gary A Gintant, Ruth L Martin. The effects of plasma proteins on delayed repolarization in vitro with cisapride, risperidone, and D, L-sotalol.
Journal of pharmacological and toxicological methods.
2007 Jul; 56(1):11-7. doi:
10.1016/j.vascn.2007.01.001. [PMID: 17350293] - Dong Won Jeong, Young Hoon Kim, Hye Young Ji, Yu Seok Youn, Kang Choon Lee, Hye Suk Lee. Analysis of carvedilol in human plasma using hydrophilic interaction liquid chromatography with tandem mass spectrometry.
Journal of pharmaceutical and biomedical analysis.
2007 Jun; 44(2):547-52. doi:
10.1016/j.jpba.2006.12.017. [PMID: 17270380] - Ching-Ling Cheng, Guei-Jen Kang, Chen-Hsi Chou. Development and validation of a high-performance liquid chromatographic method using fluorescence detection for the determination of vardenafil in small volumes of rat plasma and bile.
Journal of chromatography. A.
2007 Jun; 1154(1-2):222-9. doi:
10.1016/j.chroma.2007.03.077. [PMID: 17416379] - Sheng Xie, Jian Liang, Chun-yan Yan. [Therapeutic effects of acupoint drug-finger pressing on gastroesophageal reflux].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2007 Apr; 27(4):355-8. doi:
. [PMID: 17526179] - Anna Ollerstam, Anna H Persson, Sandra A G Visser, J Magnus Fredriksson, Tomas Forsberg, Lars B Nilsson, Göran Eklund, Stig Johan Wiklund, Johan Gabrielsson, Göran Duker, Ahmad Al-Saffar. A novel approach to data processing of the QT interval response in the conscious telemetered beagle dog.
Journal of pharmacological and toxicological methods.
2007 Jan; 55(1):35-48. doi:
10.1016/j.vascn.2006.02.009. [PMID: 16581270] - E Navarro, S-J Alonso, R Navarro, J Trujillo, E Jorge. Elenoside increases intestinal motility.
World journal of gastroenterology.
2006 Nov; 12(44):7143-8. doi:
10.3748/wjg.v12.i44.7143. [PMID: 17131476] - Xian Chen, Jason S Cordes, Jenifer A Bradley, Zhuoqian Sun, Jun Zhou. Use of arterially perfused rabbit ventricular wedge in predicting arrhythmogenic potentials of drugs.
Journal of pharmacological and toxicological methods.
2006 Nov; 54(3):261-72. doi:
10.1016/j.vascn.2006.02.005. [PMID: 16564186] - Xu-dong Tang, Hong-mei Wu, Zhi-bin Wang. [Assessment on effects of tongjiang granule on experimental reflux esophagitis in rats].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2006 Sep; 26(9):818-21. doi:
. [PMID: 17058833] - Ronald Mathison, Eldon Shaffer, Hans-Juergen Pfannkuche, David Earnest. Effects of tegaserod on bile composition and hepatic secretion in Richardson ground squirrels on an enriched cholesterol diet.
Lipids in health and disease.
2006 Jun; 5(?):15. doi:
10.1186/1476-511x-5-15. [PMID: 16792807] - Alberto P Madeiro, Andréa C Rufino, Marair G F Sartori, Edmund C Baracat, Geraldo Rodrigues De Lima, Manoel J B C Girão. The effects of bethanechol and cisapride on urodynamic parameters in patients undergoing radical hysterectomy for cervical cancer. A randomized, double-blind, placebo-controlled study.
International urogynecology journal and pelvic floor dysfunction.
2006 May; 17(3):248-52. doi:
10.1007/s00192-005-1318-1. [PMID: 15959612] - Jun Guo, Hongying Gang, Shetuan Zhang. Molecular determinants of cocaine block of human ether-á-go-go-related gene potassium channels.
The Journal of pharmacology and experimental therapeutics.
2006 May; 317(2):865-74. doi:
10.1124/jpet.105.098103. [PMID: 16397089] - Alexander N Katchman, John Koerner, Toshimasa Tosaka, Raymond L Woosley, Steven N Ebert. Comparative evaluation of HERG currents and QT intervals following challenge with suspected torsadogenic and nontorsadogenic drugs.
The Journal of pharmacology and experimental therapeutics.
2006 Mar; 316(3):1098-106. doi:
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BMC gastroenterology.
2006 Feb; 6(?):8. doi:
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Assay and drug development technologies.
2006 Feb; 4(1):73-82. doi:
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2006; 13 Suppl 5(?):114-21. doi:
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Therapeutics and clinical risk management.
2005 Dec; 1(4):299-306. doi:
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2005 Nov; 25(11):971-4. doi:
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Journal of internal medicine.
2005 Nov; 258(5):460-6. doi:
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Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2005 Oct; 25(10):880-2. doi:
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The Journal of toxicological sciences.
2005 Aug; 30(3):239-47. doi:
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Diabetes.
2005 Jul; 54(7):2212-8. doi:
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The Journal of clinical endocrinology and metabolism.
2005 May; 90(5):2843-50. doi:
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Journal of gastroenterology and hepatology.
2005 Apr; 20(4):599-605. doi:
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Pharmacology.
2005 Apr; 74(1):31-6. doi:
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Chinese journal of integrative medicine.
2005 Mar; 11(1):27-30. doi:
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Journal of pharmacological sciences.
2005; 99(5):459-71. doi:
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Expert opinion on drug safety.
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Alimentary pharmacology & therapeutics.
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European journal of clinical pharmacology.
2004 Dec; 60(10):693-701. doi:
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Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2004 Nov; 24(11):976-8. doi:
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Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
2004 Oct; 34(10):1602-9. doi:
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Clinical endocrinology.
2004 Sep; 61(3):311-9. doi:
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European journal of pharmacology.
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2004 Jul; 806(2):263-9. doi:
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American journal of physiology. Heart and circulatory physiology.
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The Indian journal of medical research.
2004 Mar; 119(3):115-20. doi:
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Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2004 Jan; 24(1):25-7. doi:
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British journal of cancer.
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
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Journal of pharmaceutical and biomedical analysis.
2003 Oct; 33(3):513-20. doi:
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Nutrition journal.
2003 Oct; 2(?):13. doi:
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Clinical pharmacology and therapeutics.
2003 Oct; 74(4):312-25. doi:
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The Journal of clinical endocrinology and metabolism.
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European journal of clinical pharmacology.
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MMW Fortschritte der Medizin.
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