sulfinpyrazone (BioDeep_00001867806)
Main id: BioDeep_00000006468
代谢物信息卡片
(+/-)-Sulfinpyrazone
化学式: C23H20N2O3S (404.119457)
中文名称: 苯磺保泰松
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)N2C(=O)C(C(=O)N2C3=CC=CC=C3)CCS(=O)C4=CC=CC=C4
InChI: InChI=1S/C23H20N2O3S/c26-22-21(16-17-29(28)20-14-8-3-9-15-20)23(27)25(19-12-6-2-7-13-19)24(22)18-10-4-1-5-11-18/h1-15,21H,16-17H2
描述信息
M - Musculo-skeletal system > M04 - Antigout preparations > M04A - Antigout preparations > M04AB - Preparations increasing uric acid excretion
D018501 - Antirheumatic Agents > D006074 - Gout Suppressants > D014528 - Uricosuric Agents
C26170 - Protective Agent > C921 - Uricosuric Agent
同义名列表
2 个代谢物同义名
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:9342
- KEGG: C07317
- KEGGdrug: D00449
- PubChem: 5342
- DrugBank: DB01138
- MeSH: Sulfinpyrazone
- CAS: 57-96-5
- PubChem: 9525
- NIKKAJI: J1.384F
- RefMet: Sulfinpyrazone
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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Journal of chromatography.
1984 Oct; 310(2):438-44. doi:
10.1016/0378-4347(84)80113-9. [PMID: 6511862] - F G Larsen, C G Larsen, R Brodersen. Warfarin-sulfinpyrazone interaction on binding to human serum albumin.
The Journal of pharmacy and pharmacology.
1984 Oct; 36(10):689-90. doi:
10.1111/j.2042-7158.1984.tb04845.x. [PMID: 6150088] - H A Strong, A G Renwick, C F George. The site of reduction of sulphinpyrazone in the rabbit.
Xenobiotica; the fate of foreign compounds in biological systems.
1984 Oct; 14(10):815-26. doi:
10.3109/00498258409151480. [PMID: 6506754] - H A Strong, J Oates, J Sembi, A G Renwick, C F George. Role of the gut flora in the reduction of sulfinpyrazone in humans.
The Journal of pharmacology and experimental therapeutics.
1984 Sep; 230(3):726-32. doi:
NULL. [PMID: 6470977] - E Strobl-Jäger, J Kaliman, H Sinzinger. Plasma factor and platelet sensitivity to prostacyclin in patients with peripheral vascular disease before and after treatment with a combination of a cyclooxygenase and a phosphodiesterase inhibitor.
Prostaglandins, leukotrienes, and medicine.
1984 Aug; 15(2):241-50. doi:
10.1016/0262-1746(84)90181-1. [PMID: 6436832] - G P Lewis, J R Smith. Prostaglandin endoperoxides and thromboxane A2 in thrombus formation in the hamster cheek pouch in vivo.
Prostaglandins.
1984 Jul; 28(1):29-41. doi:
10.1016/0090-6980(84)90111-4. [PMID: 6435186] - J Godbillon, J P Schoeller, S Gauron, G Gosset, J P Fillastre. Plasma levels and pharmacokinetics of sulphinpyrazone in renal impairment during chronic treatment: a case report.
British journal of clinical pharmacology.
1984 Jul; 18(1):107-8. doi:
10.1111/j.1365-2125.1984.tb05033.x. [PMID: 6743484] - A Del Maschio, M Livio, C Cerletti, G De Gaetano. Inhibition of human platelet cyclo-oxygenase activity by sulfinpyrazone and three of its metabolites.
European journal of pharmacology.
1984 Jun; 101(3-4):209-14. doi:
10.1016/0014-2999(84)90158-4. [PMID: 6432556] - M Cortellaro, C Boschetti, V Antoniazzi, E E Polli, G de Gaetano, A De Blasi, M Gerna, L Pezzi, S Garattini. A pharmacokinetic and platelet function study of the combined administration of metoprolol and sulfinpyrazone to healthy volunteers.
Thrombosis research.
1984 Apr; 34(1):65-74. doi:
10.1016/0049-3848(84)90106-3. [PMID: 6729769] - J Boelaert, M Schurgers, R Daneels, P Lijnen, A Amery. Sulfinpyrazone: risk for renal insufficiency.
Archives of internal medicine.
1984 Mar; 144(3):648-9. doi:
NULL. [PMID: 6703838] - J Boelaert, P Lijnen, C Bulpitt, M Schurgers, R Daneels, A Amery. Impairment of renal function in post-myocardial infarct patients treated with sulfinpyrazone.
European journal of clinical pharmacology.
1984; 26(3):409-10. doi:
10.1007/bf00548777. [PMID: 6734704] - C Prior, H Kirchmair. [Acute interstitial nephritis and kidney failure requiring dialysis after sulfinpyrazone therapy].
Acta medica Austriaca.
1984; 11(2):55-9. doi:
. [PMID: 6234742] - E Palummeri, C Borghi, R Di Ruvo, L Dacco', M Passeri. Sulphinpyrazone in cardiovascular elderly azotemic patients: a proposal of a 'guided' incremental dose schedule.
The Journal of international medical research.
1984; 12(5):271-6. doi:
10.1177/030006058401200501. [PMID: 6500166] - D Docci, M Mambelli, G Manzoni, F Turci, G Salvi. Acute renal failure secondary to sulfinpyrazone treatment after myocardial infarction.
Nephron.
1984; 37(3):213-4. doi:
10.1159/000183248. [PMID: 6738772] - B S Kuo, L A Kaplan, W A Ritschel. High-performance liquid chromatographic determination of sulfinpyrazone and its metabolites in plasma.
Arzneimittel-Forschung.
1984; 34(5):548-50. doi:
NULL. [PMID: 6540568] - M Cortellaro, C Boschetti, V Antoniazzi, G Moreo, S Repetto, E Verna, M Boscarini, A Limido, G Binaghi, E E Polli. Transcoronary platelet thromboxane A2 formation without platelet trapping in patients with coronary stenosis-effect of sulphinpyrazone treatment.
Thrombosis and haemostasis.
1983 Dec; 50(4):857-9. doi:
. [PMID: 6665767] - V Wizemann, P Buddensiek, J de Boor, S Grebe, G Schütterle. Gastrointestinal blood loss in patients undergoing maintenance dialysis.
Kidney international. Supplement.
1983 Dec; 16(?):S218-20. doi:
NULL. [PMID: 6588252] - L A Harker, J M Harlan, R Ross. Effect of sulfinpyrazone on homocysteine-induced endothelial injury and arteriosclerosis in baboons.
Circulation research.
1983 Dec; 53(6):731-9. doi:
10.1161/01.res.53.6.731. [PMID: 6640860] - J X de Vries, C Staiger, N S Wang, F Schlicht. Analysis of sulfinpyrazone and its metabolites in human plasma and urine by high-performance liquid chromatography.
Journal of chromatography.
1983 Oct; 277(?):408-13. doi:
10.1016/s0378-4347(00)84867-7. [PMID: 6643630] - G Orlandini, M Brognoli. Acute renal failure and treatment with sulfinpyrazone.
Clinical nephrology.
1983 Sep; 20(3):161-2. doi:
NULL. [PMID: 6627766] - D Docci, F Turci, G Salvi. Sulfinpyrazone-associated acute renal failure.
Clinical nephrology.
1983 Jul; 20(1):53. doi:
NULL. [PMID: 6883821] - R A Morin, W H Lyness. Potentiation of morphine analgesia after pretreatment with probenecid or sulfinpyrazone.
Pharmacology, biochemistry, and behavior.
1983 Jun; 18(6):885-9. doi:
10.1016/s0091-3057(83)80010-0. [PMID: 6889417] - D J Birkett, J O Miners, J Attwood. Evidence for a dual action of sulphinpyrazone on drug metabolism in man: theophylline-sulphinpyrazone interaction.
British journal of clinical pharmacology.
1983 May; 15(5):567-9. doi:
10.1111/j.1365-2125.1983.tb02093.x. [PMID: 6860533] - C Mahony, K M Wolfram, P V Nash, T D Bjornsson. Kinetics and metabolism of sulfinpyrazone.
Clinical pharmacology and therapeutics.
1983 Apr; 33(4):491-7. doi:
10.1038/clpt.1983.67. [PMID: 6831828] - A C de Boer, P Han, A G Turpie, R Butt, M Gent, E Genton. Platelet tests and antiplatelet drugs in coronary artery disease.
Circulation.
1983 Mar; 67(3):500-4. doi:
10.1161/01.cir.67.3.500. [PMID: 6217921] - P Lijnen, J Boelaert, P van Eeghem, R Daneels, M Schurgers, P de Jaegere, E van der Stichele, J Vincke, R Fagard, L J Verschueren, A Amery. Decrease in renal function due to sulphinpyrazone treatment early after myocardial infarction.
Clinical nephrology.
1983 Mar; 19(3):143-6. doi:
NULL. [PMID: 6340878] - I Dumont, G Decaux. Hypouricemia related to a hypersecretional tubulopathy.
Nephron.
1983; 34(4):256-9. doi:
10.1159/000183025. [PMID: 6877462]