Heptadecanoic acid (BioDeep_00000018500)

 

Secondary id: BioDeep_00000229650, BioDeep_00000400549, BioDeep_00000860614

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite PANOMIX LipidSearch BioNovoGene_Lab2019 Volatile Flavor Compounds natural product


代谢物信息卡片


heptadecanoic acid

化学式: C17H34O2 (270.2558664)
中文名称: 十七碳酸, 十七烷酸
谱图信息: 最多检出来源 Homo sapiens(feces) 0.27%

Reviewed

Last reviewed on 2024-09-29.

Cite this Page

Heptadecanoic acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/heptadecanoic_acid (retrieved 2024-11-22) (BioDeep RN: BioDeep_00000018500). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C(CCCCCCCCCCCCCC(=O)O)CC
InChI: InChI=1S/C17H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(18)19/h2-16H2,1H3,(H,18,19)

描述信息

Heptadecanoic acid, or margaric acid, is a saturated fatty acid. It occurs as a trace component of the fat and milkfat of ruminants, but it does not occur in any natural animal or vegetable fat at concentrations over half a percent. Salts and esters of heptadecanoic acid are called heptadecanoates (Wikipedia). Heptadecanoic acid is found in many foods, some of which are dandelion, potato, ginger, and green bean. Heptadecanoic acid is a constituent of Erythrina crista-galli trunkwood and bark. Common constituent of lipids, e.g. present in Physalia physalis (Portuguese-man-of-war).
Heptadecanoic acid is a fatty acid of exogenous (primarily ruminant) origin. Many "odd" length long chain amino acids are derived from the consumption of dairy fats (milk and meat). Heptadecanoic acid constitutes 0.61\\\\% of milk fat and 0.83\\\\% of ruminant meat fat. The content of heptadecanoic acid in the subcutaneous adipose tissue of humans appears to be a good biological marker of long-term milk fat intake in free-living individuals in populations with high consumption of dairy products. (PMID 9701185).
Heptadecanoic acid is an odd chain saturated fatty acid (OCS-FA). Heptadecanoic acid is associated with several diseases, including the incidence of coronary heart disease, prediabetes and type 2 diabetes as well as multiple sclerosis[1].
Heptadecanoic acid is an odd chain saturated fatty acid (OCS-FA). Heptadecanoic acid is associated with several diseases, including the incidence of coronary heart disease, prediabetes and type 2 diabetes as well as multiple sclerosis[1].

同义名列表

32 个代谢物同义名

Margaric acid, nickel (2+) salt; Omega I-123 heptadecanoic acid; Margaric acid, 1-(11)C-labeled; Margaric acid, potassium salt; Margaric acid, sodium salt; Normal-heptadecanoic acid; Normal-heptadecanoate; N-Heptadecanoic acid; N-Heptadecylic acid; HEPTADECANOIC ACID; N-Heptadecoic acid; Heptadecylic acid; Heptadecoic acid; N-Heptadecanoate; CH3-[CH2]15-COOH; N-Heptadecylate; Margarinic acid; N-Heptadecoate; Margaroic acid; Margarinsaeure; Heptadecanoate; Margaric acid; Heptadecylate; Heptadecoate; Margarinate; Margaroate; Margarate; FA(17:0); C17:0; 17:0; Heptadecanoic acid; Heptadecanoic acid



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

387 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Christopher A Bishop, Tina Machate, Janin Henkel, Matthias B Schulze, Susanne Klaus, Karolin Piepelow. Heptadecanoic Acid Is Not a Key Mediator in the Prevention of Diet-Induced Hepatic Steatosis and Insulin Resistance in Mice. Nutrients. 2023 Apr; 15(9):. doi: 10.3390/nu15092052. [PMID: 37432205]
  • Youssef Khalil, Sara Carrino, Fujun Lin, Anna Ferlin, Heena V Lad, Francesca Mazzacuva, Sara Falcone, Natalie Rivers, Gareth Banks, Danilo Concas, Carlos Aguilar, Andrew R Haynes, Andy Blease, Thomas Nicol, Raya Al-Shawi, Wendy Heywood, Paul Potter, Kevin Mills, Daniel P Gale, Peter T Clayton. Tissue Proteome of 2-Hydroxyacyl-CoA Lyase Deficient Mice Reveals Peroxisome Proliferation and Activation of ω-Oxidation. International journal of molecular sciences. 2022 Jan; 23(2):. doi: 10.3390/ijms23020987. [PMID: 35055171]
  • Xiao Gai, Peng Qian, Benqiong Guo, Yixin Zheng, Zhihao Fu, Decai Yang, Chunmei Zhu, Yang Cao, Jingbin Niu, Jianghong Ling, Jin Zhao, Hailian Shi, Guoping Liu. Heptadecanoic acid and pentadecanoic acid crosstalk with fecal-derived gut microbiota are potential non-invasive biomarkers for chronic atrophic gastritis. Frontiers in cellular and infection microbiology. 2022; 12(?):1064737. doi: 10.3389/fcimb.2022.1064737. [PMID: 36699724]
  • Kathy Trieu, Saiuj Bhat, Zhaoli Dai, Karin Leander, Bruna Gigante, Frank Qian, Andres V Ardisson Korat, Qi Sun, Xiong-Fei Pan, Federica Laguzzi, Tommy Cederholm, Ulf de Faire, Mai-Lis Hellénius, Jason H Y Wu, Ulf Risérus, Matti Marklund. Biomarkers of dairy fat intake, incident cardiovascular disease, and all-cause mortality: A cohort study, systematic review, and meta-analysis. PLoS medicine. 2021 09; 18(9):e1003763. doi: 10.1371/journal.pmed.1003763. [PMID: 34547017]
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