Bromuconazole (BioDeep_00000001768)
natural product
代谢物信息卡片
化学式: C13H12BrCl2N3O (374.9541)
中文名称: 糠菌唑
谱图信息:
最多检出来源 Viridiplantae(plant) 100%
分子结构信息
SMILES: C1C(COC1(CN2C=NC=N2)C3=C(C=C(C=C3)Cl)Cl)Br
InChI: InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2
描述信息
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3700
同义名列表
数据库引用编号
20 个数据库交叉引用编号
- ChEBI: CHEBI:81900
- KEGG: C18704
- PubChem: 3444
- Metlin: METLIN72482
- ChEMBL: CHEMBL271579
- CAS: 116255-48-2
- MoNA: CCMSLIB00001058558
- MoNA: CCMSLIB00001058838
- MoNA: EQ370002
- MoNA: EQ370005
- MoNA: EQ370001
- MoNA: EQ370009
- MoNA: EQ370004
- MoNA: EQ370008
- MoNA: EQ370007
- MoNA: EQ370003
- MoNA: EQ370006
- PMhub: MS000001144
- PubChem: 124489378
- KNApSAcK: 81900
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Zhen Qin, Weitao Wang, You Weng, Zhiwei Bao, Guiling Yang, Yuanxiang Jin. Bromuconazole exposure induces cardiotoxicity and lipid transport disorder in larval zebrafish.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2022 Dec; 262(?):109451. doi:
10.1016/j.cbpc.2022.109451
. [PMID: 36064135] - Karima Rjiba-Touati, Imen Ayed-Boussema, Hiba Hamdi, Awatef Azzebi, Salwa Abid. Bromuconazole fungicide induces cell cycle arrest and apoptotic cell death in cultured human colon carcinoma cells (HCT116) via oxidative stress process.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2022 Nov; 27(7):659-670. doi:
10.1080/1354750x.2022.2098378
. [PMID: 35968645] - Karima Rjiba-Touati, Hiba Hamdi, Asma M'nassri, Yosra Guedri, Moncef Mokni, Salwa Abid. Bromuconazole caused genotoxicity and hepatic and renal damage via oxidative stress process in Wistar rats.
Environmental science and pollution research international.
2022 Feb; 29(10):14111-14120. doi:
10.1007/s11356-021-16091-8
. [PMID: 34601692] - Shuchun Wu, Xiaofeng Ji, Jianmei Wang, Huizhen Wu, Jianzhong Han, Hu Zhang, Jie Xu, Mingrong Qian. Fungicide bromuconazole has the potential to induce hepatotoxicity at the physiological, metabolomic and transcriptomic levels in rats.
Environmental pollution (Barking, Essex : 1987).
2021 Jul; 280(?):116940. doi:
10.1016/j.envpol.2021.116940
. [PMID: 33789219] - Doaa H Abdelhadya, Mohammed Abu El-Magd, Zizy I Elbialy, Ayman A Saleh. Bromuconazole-induced hepatotoxicity is accompanied by upregulation of PXR/CYP3A1 and downregulation of CAR/CYP2B1 gene expression.
Toxicology mechanisms and methods.
2017 Sep; 27(7):544-550. doi:
10.1080/15376516.2017.1333555
. [PMID: 28532222] - Pierre Leroux, Michel Gredt, Florent Remuson, Annie Micoud, Anne-Sophie Walker. Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
Pest management science.
2013 Jan; 69(1):15-26. doi:
10.1002/ps.3408
. [PMID: 23073993] - D Shtienberg. Effects of host physiology on the development of core rot, caused by alternaria alternata, in Red Delicious apples.
Phytopathology.
2012 Aug; 102(8):769-78. doi:
10.1094/phyto-09-11-0260
. [PMID: 22624774] - Hu Zhang, Mingrong Qian, Xinquan Wang, Xiangyun Wang, Hao Xu, Qiang Wang, Minghua Wang. HPLC-MS/MS enantioseparation of triazole fungicides using polysaccharide-based stationary phases.
Journal of separation science.
2012 Apr; 35(7):773-81. doi:
10.1002/jssc.201100889
. [PMID: 22532344] - Eveline Snelders, Simone M T Camps, Anna Karawajczyk, Gijs Schaftenaar, Gert H J Kema, Henrich A van der Lee, Corné H Klaassen, Willem J G Melchers, Paul E Verweij. Triazole fungicides can induce cross-resistance to medical triazoles in Aspergillus fumigatus.
PloS one.
2012; 7(3):e31801. doi:
10.1371/journal.pone.0031801
. [PMID: 22396740] - Akos Mesterházy, Beáta Tóth, Monika Varga, Tibor Bartók, Agnes Szabó-Hevér, László Farády, Szabolcs Lehoczki-Krsjak. Role of fungicides, application of nozzle types, and the resistance level of wheat varieties in the control of Fusarium head blight and deoxynivalenol.
Toxins.
2011 Nov; 3(11):1453-83. doi:
10.3390/toxins3111453
. [PMID: 22174980]