METAZACHLOR (BioDeep_00000001165)

 

Secondary id: BioDeep_00001873725

human metabolite blood metabolite


代谢物信息卡片


2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide

化学式: C14H16ClN3O (277.09818359999997)
中文名称: 甲醇中吡唑草胺溶液
谱图信息: 最多检出来源 Homo sapiens(blood) 73.58%

分子结构信息

SMILES: CC1=C(C(=CC=C1)C)N(CN2C=CC=N2)C(=O)CCl
InChI: InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3

描述信息

CONFIDENCE standard compound; EAWAG_UCHEM_ID 269
CONFIDENCE standard compound; INTERNAL_ID 3539
CONFIDENCE standard compound; INTERNAL_ID 8416
CONFIDENCE standard compound; INTERNAL_ID 4036
CONFIDENCE standard compound; INTERNAL_ID 31

同义名列表

2 个代谢物同义名

2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide; METAZACHLOR



数据库引用编号

38 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Longfeng Wei, Jiang Ran, Zhu Li, Qinyu Zhang, Kun Guo, Shuzhen Mu, Yudan Xie, Ailin Xie, Yang Xiao. Chemical Composition, Antibacterial Activity and Mechanism of Action of Fermentation Products from Aspergillus Niger xj. Applied biochemistry and biotechnology. 2023 May; ?(?):. doi: 10.1007/s12010-023-04577-9. [PMID: 37256487]
  • Martina Vráblová, Kateřina Smutná, Ivan Koutník, Dominika Marková, Daniel Vrábl, Kamil Maciej Górecki, Radim Žebrák. A novel approach for measuring membrane permeability for organic compounds via surface plasmon resonance detection. Chemosphere. 2023 Jan; 312(Pt 1):137165. doi: 10.1016/j.chemosphere.2022.137165. [PMID: 36356810]
  • P Maršík, T Zunová, T Vaněk, R Podlipná. Metazachlor effect on poplar - Pioneer plant species for riparian buffers. Chemosphere. 2021 Jul; 274(?):129711. doi: 10.1016/j.chemosphere.2021.129711. [PMID: 33524867]
  • Ewa Szpyrka, Magdalena Słowik-Borowiec, Paulina Książek, Aneta Zwolak, Magdalena Podbielska. The difference in dissipation of clomazone and metazachlor in soil under field and laboratory conditions and their uptake by plants. Scientific reports. 2020 02; 10(1):3747. doi: 10.1038/s41598-020-60720-0. [PMID: 32111959]
  • Hanne Vercampt, Lyubka Koleva, Andon Vassilev, Jaco Vangronsveld, Ann Cuypers. Short-term phytotoxicity in Brassica napus (L.) in response to pre-emergently applied metazachlor: A microcosm study. Environmental toxicology and chemistry. 2017 01; 36(1):59-70. doi: 10.1002/etc.3538. [PMID: 27345821]
  • H Vercampt, L Koleva, A Vassilev, N Horemans, G Biermans, J Vangronsveld, A Cuypers. The functional role of the photosynthetic apparatus in the recovery of Brassica napus plants from pre-emergent metazachlor exposure. Journal of plant physiology. 2016 Jun; 196-197(?):99-105. doi: 10.1016/j.jplph.2016.04.001. [PMID: 27135933]
  • Radhika Mathur, Rajeev Patrick Das, Archana Ranjan, Chandrima Shaha. Elevated ergosterol protects Leishmania parasites against antimony-generated stress. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2015 Oct; 29(10):4201-13. doi: 10.1096/fj.15-272757. [PMID: 26116701]
  • Stefan Tresch, Monika Heilmann, Nicole Christiansen, Ralf Looser, Klaus Grossmann. Inhibition of saturated very-long-chain fatty acid biosynthesis by mefluidide and perfluidone, selective inhibitors of 3-ketoacyl-CoA synthases. Phytochemistry. 2012 Apr; 76(?):162-71. doi: 10.1016/j.phytochem.2011.12.023. [PMID: 22284369]
  • Markus Godejohann, Jean-Daniel Berset, Daniel Muff. Non-targeted analysis of wastewater treatment plant effluents by high performance liquid chromatography-time slice-solid phase extraction-nuclear magnetic resonance/time-of-flight-mass spectrometry. Journal of chromatography. A. 2011 Dec; 1218(51):9202-9. doi: 10.1016/j.chroma.2011.10.051. [PMID: 22098937]
  • Zhen-Jiang Liu, Peng-Min Yu, Song Fang, Jia-Qin Fan, Ming-Hua Wang. Development of an enzyme-linked immunosorbent assay for determination of pretilachlor in water and soil. Ecotoxicology and environmental safety. 2011 Sep; 74(6):1595-9. doi: 10.1016/j.ecoenv.2011.04.026. [PMID: 21531461]
  • S Mohr, R Berghahn, M Feibicke, S Meinecke, T Ottenströer, I Schmiedling, R Schmiediche, R Schmidt. Effects of the herbicide metazachlor on macrophytes and ecosystem function in freshwater pond and stream mesocosms. Aquatic toxicology (Amsterdam, Netherlands). 2007 May; 82(2):73-84. doi: 10.1016/j.aquatox.2007.02.001. [PMID: 17353057]
  • Thomas Götz, Peter Böger. The very-long-chain fatty acid synthase is inhibited by chloroacetamides. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2004 Jul; 59(7-8):549-53. doi: 10.1515/znc-2004-7-818. [PMID: 15813378]
  • Christian Eckermann, Bernd Matthes, Manfred Nimtz, Verena Reiser, Barbara Lederer, Peter Böger, Joachim Schröder. Covalent binding of chloroacetamide herbicides to the active site cysteine of plant type III polyketide synthases. Phytochemistry. 2003 Nov; 64(6):1045-54. doi: 10.1016/s0031-9422(03)00516-8. [PMID: 14568070]
  • Stephen Gyamfi, Ulrike Pfeifer, Michael Stierschneider, Angela Sessitsch. Effects of transgenic glufosinate-tolerant oilseed rape (Brassica napus) and the associated herbicide application on eubacterial and Pseudomonas communities in the rhizosphere. FEMS microbiology ecology. 2002 Sep; 41(3):181-90. doi: 10.1111/j.1574-6941.2002.tb00979.x. [PMID: 19709252]