2-Bromoacetaldehyde (BioDeep_00000010204)

 

Secondary id: BioDeep_00001875868

human metabolite


代谢物信息卡片


Bromoacetaldehyde, 2-(14)C-labeled

化学式: C2H3BrO (121.9367)
中文名称: 溴乙醛
谱图信息: 最多检出来源 Homo sapiens(blood) 63.25%

分子结构信息

SMILES: BrCC=O
InChI: InChI=1S/C2H3BrO/c3-1-2-4/h2H,1H2

描述信息

This compound belongs to the family of Enolates. These are salts of enols (or of the tautomeric aldehydes or ketones), in which the anionic charge is delocalized over oxygen and carbon, or similar covalent metal derivatives in which the metal is bound to oxygen.

同义名列表

4 个代谢物同义名

Bromoacetaldehyde, 2-(14)C-labeled; 2-Bromoacetaldehyde; bromoacetaldehyde; 2-Bromoacetaldehyde



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 APOE, CYP1A1, CYP2A6, CYP2B6, CYP2C18, CYP2C8, CYP2C9, CYP2E1, CYP3A4, HPGDS
Peripheral membrane protein 4 CYP1A1, CYP1B1, CYP2B6, CYP2E1
Endoplasmic reticulum membrane 11 CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2C18, CYP2C8, CYP2C9, CYP2E1, CYP3A4, CYP3A5
Nucleus 2 APOE, DR1
cytosol 2 HBB, HPGDS
dendrite 1 APOE
nucleoplasm 2 DR1, HPGDS
RNA polymerase II transcription regulator complex 1 DR1
glutamatergic synapse 1 APOE
Golgi apparatus 1 APOE
Golgi membrane 1 INS
mitochondrial inner membrane 2 CYP1A1, CYP2E1
neuronal cell body 1 APOE
plasma membrane 5 APOE, CYP2C18, CYP2C8, CYP2C9, IFNLR1
Membrane 7 APOE, CYP1B1, CYP2A6, CYP3A4, CYP3A5, HBB, IFNLR1
extracellular exosome 2 APOE, HBB
endoplasmic reticulum 1 APOE
extracellular space 3 APOE, HBB, INS
mitochondrion 2 CYP1A1, CYP1B1
intracellular membrane-bounded organelle 12 CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2C18, CYP2C8, CYP2C9, CYP2E1, CYP3A4, CYP3A5, HPGDS
Microsome membrane 9 CYP1A1, CYP1A2, CYP1B1, CYP2B6, CYP2C18, CYP2C9, CYP2E1, CYP3A4, CYP3A5
Single-pass type I membrane protein 1 IFNLR1
Secreted 3 APOE, INS, PRB1
extracellular region 4 APOE, HBB, INS, PRB1
Endosome, multivesicular body 1 APOE
Extracellular vesicle 1 APOE
Secreted, extracellular space, extracellular matrix 1 APOE
chylomicron 1 APOE
high-density lipoprotein particle 1 APOE
low-density lipoprotein particle 1 APOE
multivesicular body 1 APOE
very-low-density lipoprotein particle 1 APOE
Early endosome 1 APOE
Mitochondrion inner membrane 2 CYP1A1, CYP2E1
extracellular matrix 1 APOE
collagen-containing extracellular matrix 1 APOE
mitotic spindle 1 DR1
Secreted, extracellular space 1 APOE
blood microparticle 2 APOE, HBB
endosome lumen 1 INS
Melanosome 1 APOE
ficolin-1-rich granule lumen 1 HBB
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 APOE, INS
tertiary granule lumen 1 HBB
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
clathrin-coated endocytic vesicle membrane 1 APOE
cytoplasmic microtubule 1 CYP2A6
synaptic cleft 1 APOE
ATAC complex 1 DR1
discoidal high-density lipoprotein particle 1 APOE
hemoglobin complex 1 HBB
endocytic vesicle lumen 2 APOE, HBB
haptoglobin-hemoglobin complex 1 HBB
chylomicron remnant 1 APOE
intermediate-density lipoprotein particle 1 APOE
lipoprotein particle 1 APOE
multivesicular body, internal vesicle 1 APOE
negative cofactor 2 complex 1 DR1
interleukin-28 receptor complex 1 IFNLR1


文献列表

  • Elizabeth A Mazzio, Fran Close, Karam F A Soliman. The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. International journal of molecular sciences. 2011 Jan; 12(1):506-69. doi: 10.3390/ijms12010506. [PMID: 21340000]
  • Jong-Dae Lee, Manabu Ueno, Yusuke Miyajima, Hiroyuki Nakamura. Synthesis of boron cluster lipids: closo-dodecaborate as an alternative hydrophilic function of boronated liposomes for neutron capture therapy. Organic letters. 2007 Jan; 9(2):323-6. doi: 10.1021/ol062840+. [PMID: 17217295]
  • Béatrice Heurtault, Jean-Sébastien Thomann, Justyna Jedrzejewska, Winfried S Wels, Francis Schuber, Benoît Frisch. Liposome-based systems for anti-tumor vaccination: influence of lipopeptide adjuvants. Journal of liposome research. 2006; 16(3):205-13. doi: 10.1080/08982100600848736. [PMID: 16952875]
  • A Roth, F Rohrbach, R Weth, B Frisch, F Schuber, W S Wels. Induction of effective and antigen-specific antitumour immunity by a liposomal ErbB2/HER2 peptide-based vaccination construct. British journal of cancer. 2005 Apr; 92(8):1421-9. doi: 10.1038/sj.bjc.6602526. [PMID: 15812545]
  • Scot R Weinberger, Rosa I Viner, Patrick Ho. Tagless extraction-retentate chromatography: a new global protein digestion strategy for monitoring differential protein expression. Electrophoresis. 2002 Sep; 23(18):3182-92. doi: 10.1002/1522-2683(200209)23:18<3182::aid-elps3182>3.0.co;2-5. [PMID: 12298090]
  • K Usdin, K J Woodford. CGG repeats associated with DNA instability and chromosome fragility form structures that block DNA synthesis in vitro. Nucleic acids research. 1995 Oct; 23(20):4202-9. doi: 10.1093/nar/23.20.4202. [PMID: 7479085]
  • S Khan, C Sood, P J O'Brien. Molecular mechanisms of dibromoalkane cytotoxicity in isolated rat hepatocytes. Biochemical pharmacology. 1993 Jan; 45(2):439-47. doi: 10.1016/0006-2952(93)90081-7. [PMID: 8435094]
  • K Usdin, A V Furano. Insertion of L1 elements into sites that can form non-B DNA. Interactions of non-B DNA-forming sequences. The Journal of biological chemistry. 1989 Dec; 264(34):20736-43. doi: NULL. [PMID: 2555370]
  • M Yoshioka, K Nishidate, H Iizuka, A Nakamura, M M El-Merzabani, Z Tamura, T Miyazaki. Sensitive fluorimetry of adenine-containing compounds with high-performance liquid chromatography. Journal of chromatography. 1984 Jul; 309(1):63-71. doi: 10.1016/0378-4347(84)80006-7. [PMID: 6090491]