Exact Mass: 482.11835759999997
Exact Mass Matches: 482.11835759999997
Found 366 metabolites which its exact mass value is equals to given mass value 482.11835759999997,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Silicristin
Silychristin is a flavonolignan isolated from Silybum marianum and has been shown to exhibit inhibitory activities against lipoxygenase and prostaglandin synthetase. It has a role as a radical scavenger, a lipoxygenase inhibitor, a prostaglandin antagonist and a metabolite. It is a flavonolignan, a member of 1-benzofurans, a polyphenol, an aromatic ether and a secondary alpha-hydroxy ketone. Silicristin is a natural product found in Cunila, Anastatica hierochuntica, and other organisms with data available. Isolated from fruits of Silybum marianum (milk thistle). Silicristin is found in coffee and coffee products and green vegetables. Silicristin is found in coffee and coffee products. Silicristin is isolated from fruits of Silybum marianum (milk thistle). C26170 - Protective Agent > C2081 - Hepatoprotective Agent Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM[1][2]. Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM[1][2].
Catalposide
C22H26O12 (482.14241960000004)
Catalposide is a glycoside.
Silibinin
A - Alimentary tract and metabolism > A05 - Bile and liver therapy > A05B - Liver therapy, lipotropics > A05BA - Liver therapy Silibinin is found in coffee and coffee products. Silibinin is isolated from Silybum marianum (milk thistle D020011 - Protective Agents > D000975 - Antioxidants [Raw Data] CBA85_Silybin-B_pos_30eV.txt [Raw Data] CBA85_Silybin-B_neg_30eV.txt [Raw Data] CBA85_Silybin-B_pos_50eV.txt [Raw Data] CBA85_Silybin-B_pos_20eV.txt [Raw Data] CBA85_Silybin-B_pos_40eV.txt [Raw Data] CBA85_Silybin-B_pos_10eV.txt [Raw Data] CBA85_Silybin-B_neg_40eV.txt [Raw Data] CBA85_Silybin-B_neg_10eV.txt [Raw Data] CBA85_Silybin-B_neg_50eV.txt [Raw Data] CBA85_Silybin-B_neg_20eV.txt Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2]. Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2]. Silybin A (Silibinin A), an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration. Silybin A (Silibinin A), an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration.
Isosilybin
Constituent of Silybum marianum (milk thistle). Isosilybin is found in coffee and coffee products and green vegetables. Isosilybin is found in coffee and coffee products. Isosilybin is a constituent of Silybum marianum (milk thistle) Isosilybin is a natural product found in Silybum with data available. [Raw Data] CBA83_Isosilybin-B_pos_20eV.txt [Raw Data] CBA83_Isosilybin-B_neg_30eV.txt [Raw Data] CBA83_Isosilybin-B_neg_20eV.txt [Raw Data] CBA83_Isosilybin-B_pos_10eV.txt [Raw Data] CBA83_Isosilybin-B_pos_40eV.txt [Raw Data] CBA83_Isosilybin-B_neg_10eV.txt [Raw Data] CBA83_Isosilybin-B_pos_50eV.txt [Raw Data] CBA83_Isosilybin-B_pos_30eV.txt [Raw Data] CBA83_Isosilybin-B_neg_50eV.txt [Raw Data] CBA83_Isosilybin-B_neg_40eV.txt Isosilybin (Isosilybinin) is a flavonoid from Silybum marianum; inhibits CYP3A4 induction with an IC50 of 74 μM. Isosilybin (Isosilybinin) is a flavonoid from Silybum marianum; inhibits CYP3A4 induction with an IC50 of 74 μM.
N-[(7,8-Dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5-phosphate
3'-(2'-Galloylglucosyl)-phloroacetophenone
3-(2-Galloylglucosyl)-phloroacetophenone is found in herbs and spices. 3-(2-Galloylglucosyl)-phloroacetophenone is a constituent of Syzygium aromaticum (clove). Constituent of Syzygium aromaticum (clove). 3-(2-Galloylglucosyl)-phloroacetophenone is found in herbs and spices.
Isosilychristin
Constituent of Silybum marianum (milk thistle). Isosilychristin is found in coffee and coffee products and green vegetables. Isosilychristin is found in coffee and coffee products. Isosilychristin is a constituent of Silybum marianum (milk thistle).
3,4,5,11,12,13,21,22,23-nonahydroxy-9,14,17-trioxatetracyclo[17.4.0.0(2),.0(1),(1)]tricosa-1(23),2,4,6,19,21-hexaene-8,18-dione
3'-(6'-Galloylglucosyl)-phloroacetophenone
3-(6-Galloylglucosyl)-phloroacetophenone is found in herbs and spices. 3-(6-Galloylglucosyl)-phloroacetophenone is a constituent of Syzygium aromaticum (clove). Constituent of Syzygium aromaticum (clove). 3-(6-Galloylglucosyl)-phloroacetophenone is found in herbs and spices.
6,7,8,11,12,13,21,22,23-nonahydroxy-2,17,20-trioxatetracyclo[17.3.1.0,.0(1),(1)]tricosa-4,6,8,10,12,14-hexaene-3,16-dione
Dukunolide A
Dukunolide A is found in fruits. Dukunolide A is a constituent of Lansium domesticum (langsat)
(-)-Epigallocatechin 3'-glucuronide
(-)-Epigallocatechin 3-glucuronide is a polyphenol metabolite detected in biological fluids (PMID: 20428313).
(-)-Epigallocatechin 3-glucuronide
(-)-Epigallocatechin 3-glucuronide is a polyphenol metabolite detected in biological fluids (PMID: 20428313).
(-)-Epigallocatechin 7-glucuronide
(-)-Epigallocatechin 7-glucuronide is a polyphenol metabolite detected in biological fluids (PMID: 20428313).
AG 85 (pharmaceutical)
C27H22N4O3S (482.14125420000005)
Amenamevir
C24H26N4O5S (482.16238260000006)
J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals C254 - Anti-Infective Agent > C281 - Antiviral Agent
(2R)-4,5,7-Trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-4H-chromen-3-one
Regorafenib
C21H15ClF4N4O3 (482.07687580000004)
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01E - Protein kinase inhibitors COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib shows very robust antitumor and antiangiogenic activity[1].
Seletalisib
Silibinin
Silibinin is a flavonolignan isolated from milk thistle, Silybum marianum, that has been shown to exhibit antioxidant and antineoplastic activities. It has a role as an antioxidant, an antineoplastic agent, a hepatoprotective agent and a plant metabolite. It is a flavonolignan, a polyphenol, an aromatic ether, a benzodioxine and a secondary alpha-hydroxy ketone. Silibinin is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin and others. Silibinin is presented as a mixture of two diastereomers, silybin A and silybin B, which are found in an approximately equimolar ratio. Both in vitro and animal research suggest that silibinin has hepatoprotective (antihepatotoxic) properties that protect liver cells against toxins. Silibinin has also demonstrated in vitro anti-cancer effects against human prostate adenocarcinoma cells, estrogen-dependent and -independent human breast carcinoma cells, human ectocervical carcinoma cells, human colon cancer cells, and both small and nonsmall human lung carcinoma cells. Silibinin is a natural product found in Aspergillus iizukae, Asteraceae, and other organisms with data available. Silymarin is a mixture of flavonolignans isolated from the milk thistle plant Silybum marianum. Silymarin may act as an antioxidant, protecting hepatic cells from chemotherapy-related free radical damage. This agent may also promote the growth of new hepatic cells. (NCI04) The major active component of silymarin flavonoids extracted from seeds of the MILK THISTLE, Silybum marianum; it is used in the treatment of HEPATITIS; LIVER CIRRHOSIS; and CHEMICAL AND DRUG INDUCED LIVER INJURY, and has antineoplastic activity; silybins A and B are diastereomers. A flavonolignan isolated from milk thistle, Silybum marianum, that has been shown to exhibit antioxidant and antineoplastic activities. A - Alimentary tract and metabolism > A05 - Bile and liver therapy > A05B - Liver therapy, lipotropics > A05BA - Liver therapy D000970 - Antineoplastic Agents D020011 - Protective Agents (±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2]. Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2]. Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2]. Silybin A (Silibinin A), an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration. Silybin A (Silibinin A), an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration.
Silidianin
Silidianin is a natural product found in Silybum eburneum and Silybum marianum with data available. C26170 - Protective Agent > C2081 - Hepatoprotective Agent Silydianin is an active constituent of Silybium marianum, with exhibit anti-collagenase, antitumor and anti-elastase activities. Silydianin is a natural protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 17.38?μM. Silydianin has inhibitory effect on the in vitro production and release of oxidative products[1][2][3]. Silydianin is an active constituent of Silybium marianum, with exhibit anti-collagenase, antitumor and anti-elastase activities. Silydianin is a natural protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 17.38?μM. Silydianin has inhibitory effect on the in vitro production and release of oxidative products[1][2][3].
Catiguanin B
An organic heterotetracyclic compound that is 3,4-dihydro-2H,12H-pyrano[2,3-a]xanthene substituted by a 3,4-dihydroxyphenyl group at position 2, hydroxy groups at positions 3, 5, 9 and 10 and a 2-methoxy-2-oxoethyl group at position 12 (the 2R,3R,12S stereoisomer). It is isolated from the barks of Trichilia catigua and exhibits antioxidant activity.
(+)-4-Methylgallocatechin 3-O-beta-glucopyranoside
C22H26O12 (482.14241960000004)
Curculigoside C
C22H26O12 (482.14241960000004)
Curculigoside C is a natural product found in Curculigo orchioides with data available.
3,4,2,3,4,6,alpha-Heptahydroxychalcone 2-glucoside
Leucocyanidin 4-methylether 3-O-beta-D-galactopyranoside
C22H26O12 (482.14241960000004)
(-)-4-methylepigallocatechin 5-O-beta-glucopyranoside
C22H26O12 (482.14241960000004)
Isosilybin
A flavonolignan isolated from Silybum marianum. Isosilybin (Isosilybinin) is a flavonoid from Silybum marianum; inhibits CYP3A4 induction with an IC50 of 74 μM. Isosilybin (Isosilybinin) is a flavonoid from Silybum marianum; inhibits CYP3A4 induction with an IC50 of 74 μM.
Isosilychristin
silybin
Silybin A (Silibinin A), an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration. Silybin A (Silibinin A), an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration.
Silycristin
Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM[1][2]. Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM[1][2].
(3-hydroxy-4-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methyl 4-hydroxy-3,5-dimethoxybenzoate
C22H26O12 (482.14241960000004)
2-(alpha-Hydroxypropyl)thiamine diphosphate; 2-Hydroxypropyl-ThPP
2-(2,4,5-trihydroxyphenyl)ethyl 2-O-(3,4-dihydroxyphenylethanoyl)-beta-D-glucopyranoside|ternstroside F
C22H26O12 (482.14241960000004)
5,6,7,8,2,5-hexahydroxy-4-methoxyflavanone-beta-D-xylopyranoside
15-bromo-2,16-diacetoxy-7-hydroxy-9(11)-paraguarene|15-bromo-2,16-diacetoxy-7-hydroxy-9(11)-parguerene
C24H35BrO5 (482.16677200000004)
(R,S)-4-[(4-hydroxy-3-((4-hydroxyphenyl)ethynyl)biphenyl-2-yl)(4-hydroxyphenyl)methylene]-2,5-cyclohexadien-1-one|selaginellin A
.beta.-D-Glucopyranoside, 4-(acetyloxy)phenyl, tetraacetate
C22H26O12 (482.14241960000004)
1-(3,4-dimethoxy-5-hydroxyphenyl)-6-vanilloyl-beta-D-glucopyranose|3,4-dimethoxy-5-hydroxyphenyl 6-O-vanilloyl-beta-D-glucopyranoside
C22H26O12 (482.14241960000004)
4-hydroxy-2,6-dimethoxyphenyl 6-O-vanilloyl-beta-D-glucopyranoside
C22H26O12 (482.14241960000004)
4-Hydroxy-2-methoxyphenol 1-O-beta-D-(6-O-syringoyl) glucopyranoside
C22H26O12 (482.14241960000004)
5-O-(6-galloyl)-beta-D-glucopyranosyl methyl gentisate|rubrumoside B
(+)-disaminyl ether|Bis-((3aR)-4c-benzo[1,3]dioxol-5-yl-(3ar,6ac)-tetrahydro-furo[3,4-c]furan-1-yl)-aether|bis-((3aR)-4c-benzo[1,3]dioxol-5-yl-(3ar,6ac)-tetrahydro-furo[3,4-c]furan-1-yl)-ether
4-Hydroxy-3-methoxyphenol 1-O-(6-O-syringoyl)glucoside
C22H26O12 (482.14241960000004)
5-O-p-coumaroyl-(-)-shikimic acid 4-O-beta-D-glucopyranoside|everlastoside M
C22H26O12 (482.14241960000004)
4,6-(S)-HHDP-D-glucose|4,6-O-((S)-4,4,5,5,6,6-hexahydroxydiphenoyl)-D-glucose|4,6-O-<(S)-4,4,5,5,6,6-hexahydroxydiphenoyl>-D-glucose
glucopyranosyl 2-O-(3,4-dihydroxybenzoyl)-2,4,6-trihydroxyphenylacetate
4xi-Brom-3alpha-hydroxy-7,12-dioxo-5beta-cholan-24-saeure|4xi-bromo-3alpha-hydroxy-7,12-dioxo-5beta-cholan-24-oic acid
C24H35BrO5 (482.16677200000004)
6-O-(p-hydroxybenzoyl)antirrhinoside
C22H26O12 (482.14241960000004)
15-bromoparguer-9(11)-ene-2,7,16-triol 2,7-diacetate
C24H35BrO5 (482.16677200000004)
2,9-Dimethoxy-3,10-diacetoxy-13-(acetoxymethyl)-6,12-methano-5,6,7,12-tetrahydrodibenzo[a,d]cyclooctene-5-one
Tyr Asp Ala Asp
C20H26N4O10 (482.16488560000005)
Silybin B2
Isosilybin A is a natural product found in Aspergillus iizukae, Anastatica hierochuntica, and Silybum marianum with data available. See also: Milk Thistle (part of). Isosilybin A, a flavonolignan isolated from silymarin, has anti-prostate cancer (PCA) activity. Isosilybin A inhibits proliferation and induces G1 phase arrest and apoptosis in cancer cells, which activates apoptotic machinery in PCA cells via targeting Akt-NF-κB-androgen receptor (AR) axis[1][2]. Isosilybin A, a flavonolignan isolated from silymarin, has anti-prostate cancer (PCA) activity. Isosilybin A inhibits proliferation and induces G1 phase arrest and apoptosis in cancer cells, which activates apoptotic machinery in PCA cells via targeting Akt-NF-κB-androgen receptor (AR) axis[1][2].
Silybin A2
Isosilybin B is a natural product found in Anastatica hierochuntica and Silybum marianum with data available. See also: Milk Thistle (part of).
Lagosa
Silibinin B is a natural product found in Nymphaea alba, Aspergillus iizukae, and other organisms with data available. The major active component of silymarin flavonoids extracted from seeds of the MILK THISTLE, Silybum marianum; it is used in the treatment of HEPATITIS; LIVER CIRRHOSIS; and CHEMICAL AND DRUG INDUCED LIVER INJURY, and has antineoplastic activity; silybins A and B are diastereomers. See also: Milk Thistle (part of).
Milk Thistle Extract
A - Alimentary tract and metabolism > A05 - Bile and liver therapy > A05B - Liver therapy, lipotropics > A05BA - Liver therapy D020011 - Protective Agents > D000975 - Antioxidants (±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2]. Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2]. Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2]. Silybin A (Silibinin A), an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration. Silybin A (Silibinin A), an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration.
Silicristin
Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM[1][2]. Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM[1][2].
(2R,3R)-3,5,7-trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one
[3-hydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl 4-hydroxy-3,5-dimethoxybenzoate
C22H26O12 (482.14241960000004)
C22H26O12_Benzoic acid, 4-hydroxy-, 1-(hexopyranosyloxy)-1,4a,5,7a-tetrahydro-4a-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-5-yl ester
C22H26O12 (482.14241960000004)
C22H26O12_Benzoic acid, 4-hydroxy-, (1aS,1bS,2S,5aR,6S,6aS)-2-(beta-D-glucopyranosyloxy)-1a,1b,2,5a,6,6a-hexahydro-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-6-yl ester
C22H26O12 (482.14241960000004)
[4a-hydroxy-7-(hydroxymethyl)-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5,7a-dihydro-1H-cyclopenta[c]pyran-5-yl] 4-hydroxybenzoate
C22H26O12 (482.14241960000004)
Isosilybin A
[Raw Data] CBA86_Isosilybin-A_neg_50eV.txt [Raw Data] CBA86_Isosilybin-A_neg_40eV.txt [Raw Data] CBA86_Isosilybin-A_neg_30eV.txt [Raw Data] CBA86_Isosilybin-A_neg_20eV.txt [Raw Data] CBA86_Isosilybin-A_neg_10eV.txt [Raw Data] CBA86_Isosilybin-A_pos_50eV.txt [Raw Data] CBA86_Isosilybin-A_pos_40eV.txt [Raw Data] CBA86_Isosilybin-A_pos_30eV.txt [Raw Data] CBA86_Isosilybin-A_pos_20eV.txt [Raw Data] CBA86_Isosilybin-A_pos_10eV.txt Isosilybin A, a flavonolignan isolated from silymarin, has anti-prostate cancer (PCA) activity. Isosilybin A inhibits proliferation and induces G1 phase arrest and apoptosis in cancer cells, which activates apoptotic machinery in PCA cells via targeting Akt-NF-κB-androgen receptor (AR) axis[1][2]. Isosilybin A, a flavonolignan isolated from silymarin, has anti-prostate cancer (PCA) activity. Isosilybin A inhibits proliferation and induces G1 phase arrest and apoptosis in cancer cells, which activates apoptotic machinery in PCA cells via targeting Akt-NF-κB-androgen receptor (AR) axis[1][2].
[4a-hydroxy-7-(hydroxymethyl)-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5,7a-dihydro-1H-cyclopenta[c]pyran-5-yl] 4-hydroxybenzoate_major
C22H26O12 (482.14241960000004)
[4a-hydroxy-7-(hydroxymethyl)-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5,7a-dihydro-1H-cyclopenta[c]pyran-5-yl] 4-hydroxybenzoate_53.7\\%
C22H26O12 (482.14241960000004)
Ala Asp Asp Tyr
C20H26N4O10 (482.16488560000005)
Ala Asp Tyr Asp
C20H26N4O10 (482.16488560000005)
Ala Tyr Asp Asp
C20H26N4O10 (482.16488560000005)
Cys Cys Glu Glu
C16H26N4O9S2 (482.11411460000005)
Cys Asp Asp Met
C16H26N4O9S2 (482.11411460000005)
Cys Asp Met Asp
C16H26N4O9S2 (482.11411460000005)
Cys Glu Cys Glu
C16H26N4O9S2 (482.11411460000005)
Cys Glu Glu Cys
C16H26N4O9S2 (482.11411460000005)
Cys Glu Met Thr
C17H30N4O8S2 (482.15049799999997)
Cys Glu Thr Met
C17H30N4O8S2 (482.15049799999997)
Cys Met Asp Asp
C16H26N4O9S2 (482.11411460000005)
Cys Met Glu Thr
C17H30N4O8S2 (482.15049799999997)
Cys Met Thr Glu
C17H30N4O8S2 (482.15049799999997)
Cys Thr Glu Met
C17H30N4O8S2 (482.15049799999997)
Cys Thr Met Glu
C17H30N4O8S2 (482.15049799999997)
Asp Ala Asp Tyr
C20H26N4O10 (482.16488560000005)
Asp Ala Tyr Asp
C20H26N4O10 (482.16488560000005)
Asp Cys Asp Met
C16H26N4O9S2 (482.11411460000005)
Asp Cys Met Asp
C16H26N4O9S2 (482.11411460000005)
Asp Asp Ala Tyr
C20H26N4O10 (482.16488560000005)
Asp Asp Cys Met
C16H26N4O9S2 (482.11411460000005)
Asp Asp Phe Ser
C20H26N4O10 (482.16488560000005)
Asp Asp Met Cys
C16H26N4O9S2 (482.11411460000005)
Asp Asp Ser Phe
C20H26N4O10 (482.16488560000005)
Asp Asp Tyr Ala
C20H26N4O10 (482.16488560000005)
Asp Glu Gly Tyr
C20H26N4O10 (482.16488560000005)
Asp Glu Tyr Gly
C20H26N4O10 (482.16488560000005)
Asp Phe Asp Ser
C20H26N4O10 (482.16488560000005)
Asp Phe Ser Asp
C20H26N4O10 (482.16488560000005)
Asp Gly Glu Tyr
C20H26N4O10 (482.16488560000005)
Asp Gly Tyr Glu
C20H26N4O10 (482.16488560000005)
Asp Met Cys Asp
C16H26N4O9S2 (482.11411460000005)
Asp Met Asp Cys
C16H26N4O9S2 (482.11411460000005)
Asp Met Met Ser
C17H30N4O8S2 (482.15049799999997)
Asp Met Ser Met
C17H30N4O8S2 (482.15049799999997)
Asp Ser Asp Phe
C20H26N4O10 (482.16488560000005)
Asp Ser Phe Asp
C20H26N4O10 (482.16488560000005)
Asp Ser Met Met
C17H30N4O8S2 (482.15049799999997)
Asp Tyr Ala Asp
C20H26N4O10 (482.16488560000005)
Asp Tyr Asp Ala
C20H26N4O10 (482.16488560000005)
Asp Tyr Glu Gly
C20H26N4O10 (482.16488560000005)
Asp Tyr Gly Glu
C20H26N4O10 (482.16488560000005)
Glu Cys Cys Glu
C16H26N4O9S2 (482.11411460000005)
Glu Cys Glu Cys
C16H26N4O9S2 (482.11411460000005)
Glu Cys Met Thr
C17H30N4O8S2 (482.15049799999997)
Glu Cys Thr Met
C17H30N4O8S2 (482.15049799999997)
Glu Asp Gly Tyr
C20H26N4O10 (482.16488560000005)
Glu Asp Tyr Gly
C20H26N4O10 (482.16488560000005)
Glu Glu Cys Cys
C16H26N4O9S2 (482.11411460000005)
Glu Gly Asp Tyr
C20H26N4O10 (482.16488560000005)
Glu Gly Tyr Asp
C20H26N4O10 (482.16488560000005)
Glu Met Cys Thr
C17H30N4O8S2 (482.15049799999997)
Glu Met Thr Cys
C17H30N4O8S2 (482.15049799999997)
Glu Thr Cys Met
C17H30N4O8S2 (482.15049799999997)
Glu Thr Met Cys
C17H30N4O8S2 (482.15049799999997)
Glu Tyr Asp Gly
C20H26N4O10 (482.16488560000005)
Glu Tyr Gly Asp
C20H26N4O10 (482.16488560000005)
Phe Asp Asp Ser
C20H26N4O10 (482.16488560000005)
Phe Asp Ser Asp
C20H26N4O10 (482.16488560000005)
Phe Ser Asp Asp
C20H26N4O10 (482.16488560000005)
Gly Asp Glu Tyr
C20H26N4O10 (482.16488560000005)
Gly Asp Tyr Glu
C20H26N4O10 (482.16488560000005)
Gly Glu Asp Tyr
C20H26N4O10 (482.16488560000005)
Gly Glu Tyr Asp
C20H26N4O10 (482.16488560000005)
Gly Tyr Asp Glu
C20H26N4O10 (482.16488560000005)
Gly Tyr Glu Asp
C20H26N4O10 (482.16488560000005)
Met Cys Asp Asp
C16H26N4O9S2 (482.11411460000005)
Met Cys Glu Thr
C17H30N4O8S2 (482.15049799999997)
Met Cys Thr Glu
C17H30N4O8S2 (482.15049799999997)
Met Asp Cys Asp
C16H26N4O9S2 (482.11411460000005)
Met Asp Asp Cys
C16H26N4O9S2 (482.11411460000005)
Met Asp Met Ser
C17H30N4O8S2 (482.15049799999997)
Met Asp Ser Met
C17H30N4O8S2 (482.15049799999997)
Met Glu Cys Thr
C17H30N4O8S2 (482.15049799999997)
Met Glu Thr Cys
C17H30N4O8S2 (482.15049799999997)
Met Met Asp Ser
C17H30N4O8S2 (482.15049799999997)
Met Met Ser Asp
C17H30N4O8S2 (482.15049799999997)
Met Ser Asp Met
C17H30N4O8S2 (482.15049799999997)
Met Ser Met Asp
C17H30N4O8S2 (482.15049799999997)
Met Thr Cys Glu
C17H30N4O8S2 (482.15049799999997)
Met Thr Glu Cys
C17H30N4O8S2 (482.15049799999997)
Ser Asp Asp Phe
C20H26N4O10 (482.16488560000005)
Ser Asp Phe Asp
C20H26N4O10 (482.16488560000005)
Ser Asp Met Met
C17H30N4O8S2 (482.15049799999997)
Ser Phe Asp Asp
C20H26N4O10 (482.16488560000005)
Ser Met Asp Met
C17H30N4O8S2 (482.15049799999997)
Ser Met Met Asp
C17H30N4O8S2 (482.15049799999997)
Thr Cys Glu Met
C17H30N4O8S2 (482.15049799999997)
Thr Cys Met Glu
C17H30N4O8S2 (482.15049799999997)
Thr Glu Cys Met
C17H30N4O8S2 (482.15049799999997)
Thr Glu Met Cys
C17H30N4O8S2 (482.15049799999997)
Thr Met Cys Glu
C17H30N4O8S2 (482.15049799999997)
Thr Met Glu Cys
C17H30N4O8S2 (482.15049799999997)
Tyr Ala Asp Asp
C20H26N4O10 (482.16488560000005)
Tyr Asp Asp Ala
C20H26N4O10 (482.16488560000005)
Tyr Asp Glu Gly
C20H26N4O10 (482.16488560000005)
Tyr Asp Gly Glu
C20H26N4O10 (482.16488560000005)
Tyr Glu Asp Gly
C20H26N4O10 (482.16488560000005)
Tyr Glu Gly Asp
C20H26N4O10 (482.16488560000005)
Tyr Gly Asp Glu
C20H26N4O10 (482.16488560000005)
Tyr Gly Glu Asp
C20H26N4O10 (482.16488560000005)
Acridinium NHS ester
Dukunolide A
3'-(2''-Galloylglucosyl)-phloroacetophenone
3'-(6''-Galloylglucosyl)-phloroacetophenone
(-)-Epigallocatechin 3'-glucuronide
(-)-Epigallocatechin 3-glucuronide
(-)-Epigallocatechin 7-glucuronide
4-(?-D-Glucopyranosyloxy)-3-hydroxybenzyl 4-hydroxy-3,5-dimethoxybenzoate
C22H26O12 (482.14241960000004)
(2-METHOXY-BENZYL)-(2-METHOXY-1-METHYL-ETHYL)-AMINE
C22H26O12 (482.14241960000004)
Raltegravir potassium
D004791 - Enzyme Inhibitors > D019429 - Integrase Inhibitors > D019428 - HIV Integrase Inhibitors D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D044966 - Anti-Retroviral Agents C254 - Anti-Infective Agent > C281 - Antiviral Agent > C1660 - Anti-HIV Agent
4-Hydroxy-3-methoxyphenyl O-beta-D-(6-O-syringate)glucopyraside
C22H26O12 (482.14241960000004)
7,7-Dibromo-3,3,5,5-tetramethyl-1,1-biadamantane
C24H36Br2 (482.11835759999997)
6-[(4-indol-1-ylsulfonyl-N-prop-2-ynylanilino)methyl]-2-methyl-1H-quinazolin-4-one
C27H22N4O3S (482.14125420000005)
Ternstroside F
C22H26O12 (482.14241960000004)
A beta-D-glucoside with 2-(2,4,5-trihydroxyphenyl)ethoxy residue at the anomeric position and a [(3,4-dihydroxyphenyl)acetyl]oxy residue at position 6. Isolated from Ternstroemia japonica, it exhibits antioxidant activity.
Lactucopicrin 15-oxalate
A sesquiterpene lactone obtained by formal condensation of one of the carboxy groups of oxalic acid with the 15-hydroxy group of lactucopicrin. Found in chicory.
1-O-3,4-dimethoxy-5-hydroxyphenyl-(6-O-vanilloyl)-beta-D-glucopyranoside
C22H26O12 (482.14241960000004)
A beta-D-glucoside compound having 4,5-dimethoxybenzene-1,3-diol as the anomeric substituent and 4-hydroxy-3-methoxybenzoic acid as the substituent at position 6. It has been isolated from the stems of Gordonia chrysandra and exhibits inhibitory effect on nitric oxide production.
2-(4-(2-((3-(5-(Pyridin-2-Ylthio)thiazol-2-Yl)ureido)methyl)-1h-Imidazol-4-Yl)phenoxy)acetic Acid
(2s)-2-[3-(Aminomethyl)phenyl]-3-{(S)-Hydroxy[(1r)-2-Methyl-1-{[(2-Phenylethyl)sulfonyl]amino}propyl]phosphoryl}propanoic Acid
C22H31N2O6PS (482.16403560000003)
N-[1-(Aminomethyl)cyclopropyl]-3-(morpholin-4-ylsulfonyl)-N~2~-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-L-alaninamide
Regorafenib
C21H15ClF4N4O3 (482.07687580000004)
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01E - Protein kinase inhibitors COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib shows very robust antitumor and antiangiogenic activity[1].
Amenamevir
C24H26N4O5S (482.16238260000006)
J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals C254 - Anti-Infective Agent > C281 - Antiviral Agent
2,3-Dihydroxybenzoyl 5-adenylate(1-)
C17H17N5O10P- (482.07130120000005)
Conjugate base of 2,3-dihydroxybenzoyl 5-adenylate.
(3,4-Dihydroxybenzoate)adenylate
C17H17N5O10P- (482.07130120000005)
3-(O-beta-glucosyl)-dioxindole-3-acetyl-aspartic acid
7,8-H2pterin-6-ylmethyl-l-(4-aminophenyl)-1-deoxy-D-ribitol 5-phosphate
[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] 3-amino-4-hydroxybenzoate
Crinecerfont
C27H28ClFN2OS (482.15948000000003)
C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist
catiguanin A
An organic heterotetracyclic compound that is 3,4-dihydro-2H,12H-pyrano[2,3-a]xanthene substituted by a 3,4-dihydroxyphenyl group at position 2, hydroxy groups at positions 3, 5, 9 and 10 and a 2-methoxy-2-oxoethyl group at position 12 (the 2R,3R,12R stereoisomer). It is isolated from the barks of Trichilia catigua and exhibits antioxidant activity.
Epigallocatechin-3-O-ferulate
A natural product found in Parapiptadenia rigida.
N-(2-furanylmethyl)-2-[[4-oxo-3-[3-(1-pyrrolidinyl)propyl]-[1]benzothiolo[3,2-d]pyrimidin-2-yl]thio]acetamide
2-Benzoylimino-1-(2-furanylmethyl)-10-methyl-5-oxo-3-dipyrido[3,4-c:1,2-f]pyrimidinecarboxylic acid ethyl ester
3-[(4-methyl-1-piperazinyl)sulfonyl]-N-(4-phenyl-2-thiazolyl)-N-prop-2-enylbenzamide
N-(5-ethyl-1,3,4-thiadiazol-2-yl)-4-({[3-methyl-1-(4-methylphenyl)-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]methyl}amino)benzenesulfonamide
C22H22N6O3S2 (482.11947419999996)
N-(1H-benzo[f]benzimidazol-2-ylmethyl)-2-(4-morpholinyl)-9-(3-thiophenyl)-6-purinamine
(E)-2-cyano-N-(1,1-dioxothiolan-3-yl)-3-[2-(4-fluorophenoxy)-9-methyl-4-oxopyrido[1,2-a]pyrimidin-3-yl]prop-2-enamide
C23H19FN4O5S (482.10601360000004)
N-[2-(3,4-dimethoxyphenyl)ethyl]-4-dimethoxyphosphoryl-2-(1-naphthalenyl)-5-oxazolamine
C25H27N2O6P (482.16066520000004)
N-[5-(4-morpholinylsulfonyl)-2-(1-pyrrolidinyl)phenyl]-2-oxo-1H-quinoline-4-carboxamide
C24H26N4O5S (482.16238260000006)
2-[1-(4-chlorophenyl)-5-oxo-3-(2-pyridin-4-ylethyl)-2-sulfanylidene-4-imidazolidinyl]-N-(4-fluorophenyl)acetamide
[(3aR,4R,9bR)-8-(4-fluorophenyl)-1-(4-methoxyphenyl)sulfonyl-5-methyl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinolin-4-yl]methanol
C26H27FN2O4S (482.16754740000005)
[(3aR,4S,9bR)-8-(4-fluorophenyl)-1-(4-methoxyphenyl)sulfonyl-5-methyl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinolin-4-yl]methanol
C26H27FN2O4S (482.16754740000005)
[(1S,2aR,8bR)-2-(1,3-benzodioxol-5-ylmethyl)-4-(4-fluorophenyl)sulfonyl-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-1-yl]methanol
N-[2-[(2S,5S,6R)-6-(hydroxymethyl)-5-[(2-methylphenyl)sulfonylamino]oxan-2-yl]ethyl]-2-methylbenzenesulfonamide
2-[(1S,3R,4aS,9aR)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b][1]benzofuran-3-yl]-N-[(2,5-difluorophenyl)methyl]acetamide
C22H24F2N2O6S (482.13230680000004)
N-[2-[(2S,5R,6S)-6-(hydroxymethyl)-5-[(2-methylphenyl)sulfonylamino]oxan-2-yl]ethyl]-2-methylbenzenesulfonamide
N-[2-[(2R,5S,6R)-6-(hydroxymethyl)-5-[(2-methylphenyl)sulfonylamino]oxan-2-yl]ethyl]-2-methylbenzenesulfonamide
N-[2-[(2R,5R,6S)-6-(hydroxymethyl)-5-[(2-methylphenyl)sulfonylamino]oxan-2-yl]ethyl]-2-methylbenzenesulfonamide
N-[2-[(2R,5S,6S)-6-(hydroxymethyl)-5-[(2-methylphenyl)sulfonylamino]-2-oxanyl]ethyl]-2-methylbenzenesulfonamide
2-[(1R,3S,4aS,9aR)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b][1]benzofuran-3-yl]-N-[(2,5-difluorophenyl)methyl]acetamide
C22H24F2N2O6S (482.13230680000004)
N-[2-[(2S,5S,6S)-6-(hydroxymethyl)-5-[(2-methylphenyl)sulfonylamino]-2-oxanyl]ethyl]-2-methylbenzenesulfonamide
N-[2-[(2S,5R,6R)-6-(hydroxymethyl)-5-[(2-methylphenyl)sulfonylamino]-2-oxanyl]ethyl]-2-methylbenzenesulfonamide
N-[(3,5-difluorophenyl)methyl]-2-[(2S,3R,6S)-2-(hydroxymethyl)-3-[(2-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetamide
C22H24F2N2O6S (482.13230680000004)
N-[(3,5-difluorophenyl)methyl]-2-[(2S,3S,6R)-2-(hydroxymethyl)-3-[(2-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetamide
C22H24F2N2O6S (482.13230680000004)
N-[(3,5-difluorophenyl)methyl]-2-[(2S,3S,6S)-2-(hydroxymethyl)-3-[(2-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetamide
C22H24F2N2O6S (482.13230680000004)
N-[(3,4-dichlorophenyl)methyl]-2-[(2S,3R,6R)-3-[[[(3,5-dimethyl-4-isoxazolyl)amino]-oxomethyl]amino]-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-6-yl]acetamide
N-[(3,4-dichlorophenyl)methyl]-2-[(2S,3S,6R)-3-[[[(3,5-dimethyl-4-isoxazolyl)amino]-oxomethyl]amino]-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-6-yl]acetamide
N-[(3,4-dichlorophenyl)methyl]-2-[(2S,3S,6S)-3-[[[(3,5-dimethyl-4-isoxazolyl)amino]-oxomethyl]amino]-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-6-yl]acetamide
2-[(2R,3S,6S)-2-(hydroxymethyl)-3-[(1-methyl-4-imidazolyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]-N-(4-phenylphenyl)acetamide
C24H26N4O5S (482.16238260000006)
2-[(2R,3S,6R)-2-(hydroxymethyl)-3-[(1-methyl-4-imidazolyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]-N-(4-phenylphenyl)acetamide
C24H26N4O5S (482.16238260000006)
2-[(1S,3S,4aS,9aR)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(2,5-difluorophenyl)methyl]acetamide
C22H24F2N2O6S (482.13230680000004)
2-[(1S,3R,4aR,9aS)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(2,5-difluorophenyl)methyl]acetamide
C22H24F2N2O6S (482.13230680000004)
[(1R,2aR,8bR)-2-(1,3-benzodioxol-5-ylmethyl)-4-(4-fluorophenyl)sulfonyl-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-1-yl]methanol
[(1R,2aS,8bS)-2-(1,3-benzodioxol-5-ylmethyl)-4-(4-fluorophenyl)sulfonyl-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-1-yl]methanol
(1R,9S,10S,11S)-12-[(2,5-difluorophenyl)carbamoyl]-10-(hydroxymethyl)-6-oxo-5-pyridin-3-yl-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxylic acid
C24H20F2N4O5 (482.14016940000005)
[(3aS,4R,9bS)-1-(2-fluorophenyl)sulfonyl-8-(3-methoxyphenyl)-5-methyl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinolin-4-yl]methanol
C26H27FN2O4S (482.16754740000005)
N-[2-[(2R,5R,6R)-6-(hydroxymethyl)-5-[(2-methylphenyl)sulfonylamino]-2-oxanyl]ethyl]-2-methylbenzenesulfonamide
N-[(3,5-difluorophenyl)methyl]-2-[(2S,3R,6R)-2-(hydroxymethyl)-3-[(2-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetamide
C22H24F2N2O6S (482.13230680000004)
N-[(3,5-difluorophenyl)methyl]-2-[(2R,3S,6S)-2-(hydroxymethyl)-3-[(2-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetamide
C22H24F2N2O6S (482.13230680000004)
N-[(3,5-difluorophenyl)methyl]-2-[(2R,3S,6R)-2-(hydroxymethyl)-3-[(2-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetamide
C22H24F2N2O6S (482.13230680000004)
N-[(3,5-difluorophenyl)methyl]-2-[(2R,3R,6S)-2-(hydroxymethyl)-3-[(2-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetamide
C22H24F2N2O6S (482.13230680000004)
N-[(3,5-difluorophenyl)methyl]-2-[(2R,3R,6R)-2-(hydroxymethyl)-3-[(2-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetamide
C22H24F2N2O6S (482.13230680000004)
N-[(3,4-dichlorophenyl)methyl]-2-[(2R,3S,6S)-3-[[[(3,5-dimethyl-4-isoxazolyl)amino]-oxomethyl]amino]-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-6-yl]acetamide
N-[(3,4-dichlorophenyl)methyl]-2-[(2R,3S,6R)-3-[[[(3,5-dimethyl-4-isoxazolyl)amino]-oxomethyl]amino]-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-6-yl]acetamide
N-[(3,4-dichlorophenyl)methyl]-2-[(2R,3R,6S)-3-[[[(3,5-dimethyl-4-isoxazolyl)amino]-oxomethyl]amino]-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-6-yl]acetamide
N-[(3,4-dichlorophenyl)methyl]-2-[(2R,3R,6R)-3-[[[(3,5-dimethyl-4-isoxazolyl)amino]-oxomethyl]amino]-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-6-yl]acetamide
2-[(2S,3R,6R)-2-(hydroxymethyl)-3-[(1-methyl-4-imidazolyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]-N-(4-phenylphenyl)acetamide
C24H26N4O5S (482.16238260000006)
2-[(2S,3R,6S)-2-(hydroxymethyl)-3-[(1-methyl-4-imidazolyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]-N-(4-phenylphenyl)acetamide
C24H26N4O5S (482.16238260000006)
2-[(2S,3S,6R)-2-(hydroxymethyl)-3-[(1-methyl-4-imidazolyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]-N-(4-phenylphenyl)acetamide
C24H26N4O5S (482.16238260000006)
2-[(2R,3R,6S)-2-(hydroxymethyl)-3-[(1-methyl-4-imidazolyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]-N-(4-phenylphenyl)acetamide
C24H26N4O5S (482.16238260000006)
2-[(1R,3R,4aR,9aS)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(2,5-difluorophenyl)methyl]acetamide
C22H24F2N2O6S (482.13230680000004)
2-[(1R,3S,4aR,9aS)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(2,5-difluorophenyl)methyl]acetamide
C22H24F2N2O6S (482.13230680000004)
2-[(1R,3R,4aS,9aR)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(2,5-difluorophenyl)methyl]acetamide
C22H24F2N2O6S (482.13230680000004)
2-[(1S,3S,4aR,9aS)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(2,5-difluorophenyl)methyl]acetamide
C22H24F2N2O6S (482.13230680000004)
[(1S,2aS,8bS)-2-(1,3-benzodioxol-5-ylmethyl)-4-(4-fluorophenyl)sulfonyl-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-1-yl]methanol
(1S,9R,10R,11R)-12-[(2,5-difluorophenyl)carbamoyl]-10-(hydroxymethyl)-6-oxo-5-pyridin-3-yl-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxylic acid
C24H20F2N4O5 (482.14016940000005)
[(3aR,4R,9bR)-1-(2-fluorophenyl)sulfonyl-8-(3-methoxyphenyl)-5-methyl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinolin-4-yl]methanol
C26H27FN2O4S (482.16754740000005)
[(3aS,4S,9bS)-1-(2-fluorophenyl)sulfonyl-8-(3-methoxyphenyl)-5-methyl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinolin-4-yl]methanol
C26H27FN2O4S (482.16754740000005)
[(3aS,4R,9bS)-8-(4-fluorophenyl)-1-(4-methoxyphenyl)sulfonyl-5-methyl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinolin-4-yl]methanol
C26H27FN2O4S (482.16754740000005)
[(3aS,4S,9bS)-8-(4-fluorophenyl)-1-(4-methoxyphenyl)sulfonyl-5-methyl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinolin-4-yl]methanol
C26H27FN2O4S (482.16754740000005)
(3R)-2-tert-butylsulfinyl-4-[3-(3-fluorophenyl)phenyl]-3-(2-hydroxyethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxylic acid
C26H27FN2O4S (482.16754740000005)
6-[3,5-Dihydroxy-4-[2-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propyl]phenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
C22H26O12 (482.14241960000004)
2-hydroxy-4-[4-[(5Z)-5-[(Z)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoylamino]benzoic acid
2-(2,5-dihydroxy-4-methoxyphenyl)-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,4-dihydro-2H-1-benzopyran-3,5,7-triol
C22H26O12 (482.14241960000004)
4-methyl-3-(4-morpholinylsulfonyl)benzoic acid [3-(1H-benzimidazol-2-yl)-3-cyano-2-oxopropyl] ester
[2-(acetyloxy)-2-(9-{[(2E)-2-methylbut-2-enoyl]oxy}-2-oxo-2H,8H,9H-furo[2,3-h]chromen-8-yl)propoxy]sulfonic acid
Silychristin
A flavonolignan isolated from Silybum marianum and has been shown to exhibit inhibitory activities against lipoxygenase and prostaglandin synthetase. Silychristin is a flavonolignan isolated from Silybum marianum and has been shown to exhibit inhibitory activities against lipoxygenase and prostaglandin synthetase. It has a role as a radical scavenger, a lipoxygenase inhibitor, a prostaglandin antagonist and a metabolite. It is a flavonolignan, a member of 1-benzofurans, a polyphenol, an aromatic ether and a secondary alpha-hydroxy ketone. Silicristin is a natural product found in Cunila, Anastatica hierochuntica, and other organisms with data available. C26170 - Protective Agent > C2081 - Hepatoprotective Agent Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM[1][2]. Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM[1][2].
3,5,7-Trihydroxy-2-[7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1-benzouran-4-yl]-2,3-dihydrochromen-4-one
2-(2,5-dihydroxy-4-methoxyphenyl)-5,6,8-trihydroxy-7-[(3,4,5-trihydroxyoxan-2-yl)oxy]-2,3-dihydro-1-benzopyran-4-one
(1r,3r,6s,7r)-3-hydroxy-10-(4-hydroxy-3-methoxyphenyl)-8-(3,5,7-trihydroxy-4-oxo-2,3-dihydro-1-benzopyran-2-yl)-4-oxatricyclo[4.3.1.0³,⁷]dec-8-en-2-one
(3r)-3,5,7-trihydroxy-2-[(3r)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-1-benzopyran-4-one
(1r,2r,3r,4s)-3-(acetyloxy)-2,4,9-trihydroxy-2-methyl-5,10-dioxo-11-(λ⁵-diazynylidene)-1h,3h,4h-benzo[b]fluoren-1-yl 2-methylpropanoate
C24H22N2O9 (482.13252420000003)
9-hydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-3-(hydroxymethyl)-7-methoxy-2,3-dihydro-1,4,5-trioxatetraphen-10-one
(2r,3r)-3,5,7-trihydroxy-2-[(2r,3s)-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1-benzofuran-4-yl]-2,3-dihydro-1-benzopyran-4-one
(2r,3s)-2-(3-hydroxy-4-methoxy-5-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)-3,4-dihydro-2h-1-benzopyran-3,5,7-triol
C22H26O12 (482.14241960000004)
(1s,2s,4s,5s,6r,10s)-2-(hydroxymethyl)-10-{[(2s,3s,5r)-3,4,5,6-tetrahydroxyoxan-2-yl]oxy}-3,9-dioxatricyclo[4.4.0.0²,⁴]dec-7-en-5-yl 4-methoxybenzoate
C22H26O12 (482.14241960000004)
7,15-bis[2-(dimethylamino)ethyl]-5,13-dimethoxy-2,9,10-trithiatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaene-4,12-diol
C22H30N2O4S3 (482.13676200000003)
(7r,8s,8as)-8-hydroxy-7-methyl-6-oxo-3-[(1e)-prop-1-en-1-yl]-8,8a-dihydro-1h-isochromen-7-yl 3,5-dichloro-2,4-dimethoxy-6-methylbenzoate
(10r,11r,13r,14r,15s)-3,4,5,11,14,20,21,22-octahydroxy-13-(hydroxymethyl)-9,12,16-trioxatetracyclo[16.4.0.0²,⁷.0¹⁰,¹⁵]docosa-1(18),2,4,6,19,21-hexaene-8,17-dione
methyl 2-[(2s,3s,12s)-2-(3,4-dihydroxyphenyl)-3,5,9,10-tetrahydroxy-2,3,4,12-tetrahydro-1,7-dioxatetraphen-12-yl]acetate
(10r,11s,13r,14r,15s)-3,4,5,11,14,20,21,22-octahydroxy-13-(hydroxymethyl)-9,12,16-trioxatetracyclo[16.4.0.0²,⁷.0¹⁰,¹⁵]docosa-1(18),2,4,6,19,21-hexaene-8,17-dione
methyl 2-[(2s,3s,12r)-2-(3,4-dihydroxyphenyl)-3,5,9,10-tetrahydroxy-2,3,4,12-tetrahydro-1,7-dioxatetraphen-12-yl]acetate
(1ar,1br,3r,3ar,5s,7br,9r,9ar)-3-(acetyloxy)-5-[(1s)-1-bromo-2-hydroxyethyl]-1a,5,7b-trimethyl-1h,1bh,2h,3h,3ah,4h,6h,8h,9h,9ah-cyclopropa[a]phenanthren-9-yl acetate
C24H35BrO5 (482.16677200000004)
12-[(2r,3r,4s,5s)-3,4-dihydroxy-5-[(1s)-1-hydroxyethyl]oxolan-2-yl]-15-hydroxy-3,17-dimethoxy-5-methyl-9-oxatetracyclo[8.8.0.0²,⁷.0¹¹,¹⁶]octadeca-1(10),2(7),3,5,11(16),12,14,17-octaen-8-one
(4-hydroxy-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methyl 3-hydroxy-2,6-dimethoxybenzoate
C22H26O12 (482.14241960000004)