Exact Mass: 455.13688060000004

Exact Mass Matches: 455.13688060000004

Found 231 metabolites which its exact mass value is equals to given mass value 455.13688060000004, within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error 0.01 dalton.

5,10-Methenyltetrahydrofolic acid

(6aR)-8-(4-{[(1S)-1,3-dicarboxypropyl]-C-hydroxycarbonimidoyl}phenyl)-1-hydroxy-3-imino-3H,4H,5H,6H,6aH,7H-8lambda5-imidazo[1,5-f]pteridin-8-ylium

C20H21N7O6 (455.15532460000003)


Folate is important for cells and tissues that rapidly divide. Cancer cells divide rapidly, and drugs that interfere with folate metabolism are used to treat cancer. Methotrexate is a drug often used to treat cancer because it inhibits the production of the active form, tetrahydrofolate. Unfortunately, methotrexate can be toxic, producing side effects such as inflammation in the digestive tract that make it difficult to eat normally. Folinic acid is a form of folate that can help rescue or reverse the toxic effects of methotrexate. Folinic acid is not the same as folic acid. Folic acid supplements have little established role in cancer chemotherapy. There have been cases of severe adverse effects of accidental substitution of folic acid for folinic acid in patients receiving methotrexate cancer chemotherapy. It is important for anyone receiving methotrexate to follow medical advice on the use of folic or folinic acid supplements. Low concentrations of folate, vitamin B12, or vitamin B6 may increase your level of homocysteine, an amino acid normally found in your blood. There is evidence that an elevated homocysteine level is an independent risk factor for heart disease and stroke. The evidence suggests that high levels of homocysteine may damage coronary arteries or make it easier for blood clotting cells called platelets to clump together and form a clot. However, there is currently no evidence available to suggest that lowering homocysteine with vitamins will reduce your risk of heart disease. Clinical intervention trials are needed to determine whether supplementation with folic acid, vitamin B12 or vitamin B6 can lower your risk of developing coronary heart disease. Methylene tetrahydrofolate (CH2FH4) is formed from tetrahydrofolate by the addition of methylene groups from one of three carbon donors: formaldehyde, serine, or glycine. Methyl tetrahydrofolate(CH3FH4) can be made from methylene tetrahydrofolate by reduction of the methylene group, and formyl tetrahydrofolate (CHOFH4, folinic acid) is made by oxidation of methylene tetrahydrofolate. In the form of a series of tetrahydrofolate compounds, folate derivatives are substrates in a number of single-carbon-transfer reactions, and also are involved in the synthesis of dTMP (2-deoxythymidine-5-phosphate) from dUMP (2-deoxyuridine-5-phosphate). It helps convert vitamin B12 to one of its coenzyme forms and helps synthesize the DNA required for all rapidly growing cells.

   

Tryptophol [xylosyl-(1->6)-glucoside]

2-[2-(1H-indol-3-yl)ethoxy]-6-{[(3,4,5-trihydroxyoxan-2-yl)oxy]methyl}oxane-3,4,5-triol

C21H29NO10 (455.17913740000006)


Tryptophol [xylosyl-(1->6)-glucoside] is found in coffee and coffee products. Tryptophol [xylosyl-(1->6)-glucoside] is isolated from Lycium chinense (Chinese boxthom). Isolated from Lycium chinense (Chinese boxthom). Tryptophol [xylosyl-(1->6)-glucoside] is found in tea, coffee and coffee products, and herbs and spices.

   

(4S)-4-[[4-(3-Amino-1-oxo-5,6,6a,7-tetrahydro-2H-imidazo[1,5-f]pteridin-10-ium-8-yl)benzoyl]amino]-5-hydroxy-5-oxopentanoate

(4S)-4-[[4-(3-Amino-1-oxo-5,6,6a,7-tetrahydro-2H-imidazo[1,5-F]pteridin-10-ium-8-yl)benzoyl]amino]-5-hydroxy-5-oxopentanoic acid

C20H21N7O6 (455.15532460000003)


   

Apafant

3-[7-(2-chlorophenyl)-13-methyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0²,⁶]trideca-2(6),4,7,10,12-pentaen-4-yl]-1-(morpholin-4-yl)propan-1-one

C22H22ClN5O2S (455.11826620000005)


C78275 - Agent Affecting Blood or Body Fluid > C1327 - Antiplatelet Agent D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D006401 - Hematologic Agents > D005343 - Fibrinolytic Agents D050299 - Fibrin Modulating Agents D002317 - Cardiovascular Agents

   

N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(6-methyl-2-oxo-3-phenylmethanesulfonylamino-2H-pyridin-1-yl)-acetamide

N-[(6-Imino-2-methyl-1,6-dihydropyridin-3-yl)methyl]-2-[6-methyl-2-oxo-3-(phenylmethanesulphonamido)-1,2-dihydropyridin-1-yl]ethanimidic acid

C22H25N5O4S (455.16271700000004)


   

Clevidipine

Methyl 5-{[(butanoyloxy)methoxy]carbonyl}-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3-carboxylic acid

C21H23Cl2NO6 (455.0902358)


C - Cardiovascular system > C08 - Calcium channel blockers > C08C - Selective calcium channel blockers with mainly vascular effects > C08CA - Dihydropyridine derivatives C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent > C333 - Calcium Channel Blocker D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators C93038 - Cation Channel Blocker

   

N-Formylmethionyl-methionyl-phenylalanine

2-{[1-hydroxy-2-({1-hydroxy-2-[(hydroxymethylidene)amino]-4-(methylsulphanyl)butylidene}amino)-4-(methylsulphanyl)butylidene]amino}-3-phenylpropanoic acid

C20H29N3O5S2 (455.15485440000003)


   

N-Pyridazin-3-yl-4-[[3-[5-(trifluoromethyl)pyridin-2-yl]oxyphenyl]methylidene]piperidine-1-carboxamide

N-(pyridazin-3-yl)-4-[(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methylidene]piperidine-1-carboxamide

C23H20F3N5O2 (455.1569016)


Redafamdastat (PF-04457845) is a highly efficacious and selective FAAH inhibitor with IC50 values is 7.2±0.63 nM and 7.4±0.62 nM for hFAAH and rFAAH, respectively.

   

Pradigastat

2-{4-[4-(5-{[6-(trifluoromethyl)pyridin-3-yl]amino}pyridin-2-yl)phenyl]cyclohexyl}acetic acid

C25H24F3N3O2 (455.182052)


C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent Pradigastat (LCQ-908) is a potent, selective and orally active diacylglycerol acyltransferase 1 (DGAT1) inhibitor. Pradigastat has anti-obesity and anti-diabetic effects[1][2].

   

2-[[4-[(2-Amino-4-oxo-3H-pteridin-6-yl)methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid

2-[(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}phenyl)formamido]-5-methoxy-5-oxopentanoic acid

C20H21N7O6 (455.15532460000003)


   

2-[[4-[(2-Amino-4-oxo-3H-pteridin-6-yl)methylamino]benzoyl]amino]-4-methylpentanedioic acid

2-[(4-{[(4-hydroxy-2-imino-1,2-dihydropteridin-6-yl)methyl]amino}phenyl)formamido]-4-methylpentanedioate

C20H21N7O6 (455.15532460000003)


   

5-O-(Butanoyloxymethyl) 3-O-methyl (4R)-4-(2,3-dichlorophenyl)-2,6-dimethyl-3,4-dihydropyridine-3,5-dicarboxylate

5-O-(Butanoyloxymethyl) 3-O-methyl (4R)-4-(2,3-dichlorophenyl)-2,6-dimethyl-3,4-dihydropyridine-3,5-dicarboxylic acid

C21H23Cl2NO6 (455.0902358)


   

5,10-methylenetetrahydrofolate

4-Carboxy-4-[(4-{3-imino-1-oxido-3H,4H,5H,6H,6ah,7H,8H,9H-imidazo[1,5-F]pteridin-8-yl}phenyl)formamido]butanoic acid

C20H21N7O6 (455.15532460000003)


5,10-methylenetetrahydrofolate is slightly soluble (in water) and a weakly acidic compound (based on its pKa). 5,10-methylenetetrahydrofolate can be found in a number of food items such as yellow bell pepper, mexican groundcherry, celery leaves, and hard wheat, which makes 5,10-methylenetetrahydrofolate a potential biomarker for the consumption of these food products. The diastereoisomer [6R]-5,10-methylene-THF is the key endogenous one-carbon donor and a co-substrate of the TS (thymidylate synthase) enzyme for methylation of 2-deoxy-uridine-5-monophosphate (dUMP) to 2-deoxy-thymidine-5-monophosphate (dTMP). The coenzyme is necessary for the biosynthesis of thymidine and is the C1-donor in the reactions catalyzed by TS and thymidylate synthase (FAD) .

   
   
   

Aristolactam I N-beta-glucoside

Aristolactam I N-beta-glucoside

C23H21NO9 (455.1216256)


   
   

N13-1-beta-L-digitoxosylarcyriaflavin

N13-1-beta-L-digitoxosylarcyriaflavin

C26H21N3O5 (455.14811360000004)


   
   

N12-5(S)-N13-1(R)-L-rhamnosylarcyriaflavin A

N12-5(S)-N13-1(R)-L-rhamnosylarcyriaflavin A

C25H17N3O6 (455.1117302)


   
   

Ala Asn His Asp

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

Clevidipine

Cleviprex (Clevidipine)

C21H23Cl2NO6 (455.0902358)


C - Cardiovascular system > C08 - Calcium channel blockers > C08C - Selective calcium channel blockers with mainly vascular effects > C08CA - Dihydropyridine derivatives C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent > C333 - Calcium Channel Blocker D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators C93038 - Cation Channel Blocker

   
   

Ala Asp His Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-carboxypropanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanoic acid

C17H25N7O8 (455.176453)


   

Ala Asp Asn His

(3S)-3-[(2S)-2-aminopropanamido]-3-{[(1S)-2-carbamoyl-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Ala His Asp Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carboxypropanamido]-3-carbamoylpropanoic acid

C17H25N7O8 (455.176453)


   

Ala His Asn Asp

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

Ala Asn Asp His

(3S)-3-[(2S)-2-[(2S)-2-aminopropanamido]-3-carbamoylpropanamido]-3-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Cys Cys Cys Lys

(2S)-6-amino-2-[(2R)-2-[(2R)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-sulfanylpropanamido]-3-sulfanylpropanamido]hexanoic acid

C15H29N5O5S3 (455.13307440000005)


   

Cys Cys Cys Gln

(2S)-2-[(2R)-2-[(2R)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-sulfanylpropanamido]-3-sulfanylpropanamido]-4-carbamoylbutanoic acid

C14H25N5O6S3 (455.096691)


   

Cys Cys Lys Cys

(2R)-2-[(2S)-6-amino-2-[(2R)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-sulfanylpropanamido]hexanamido]-3-sulfanylpropanoic acid

C15H29N5O5S3 (455.13307440000005)


   

Cys Cys Gln Cys

(2R)-2-[(2S)-2-[(2R)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-sulfanylpropanamido]-4-carbamoylbutanamido]-3-sulfanylpropanoic acid

C14H25N5O6S3 (455.096691)


   

Cys Gly Asn Tyr

(2S)-2-[(2S)-2-{2-[(2R)-2-amino-3-sulfanylpropanamido]acetamido}-3-carbamoylpropanamido]-3-(4-hydroxyphenyl)propanoic acid

C18H25N5O7S (455.147462)


   

Cys Gly Tyr Asn

(2S)-2-[(2S)-2-{2-[(2R)-2-amino-3-sulfanylpropanamido]acetamido}-3-(4-hydroxyphenyl)propanamido]-3-carbamoylpropanoic acid

C18H25N5O7S (455.147462)


   

Cys Lys Cys Cys

(2R)-2-[(2R)-2-[(2S)-6-amino-2-[(2R)-2-amino-3-sulfanylpropanamido]hexanamido]-3-sulfanylpropanamido]-3-sulfanylpropanoic acid

C15H29N5O5S3 (455.13307440000005)


   

Cys Asn Gly Tyr

(2S)-2-{2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetamido}-3-(4-hydroxyphenyl)propanoic acid

C18H25N5O7S (455.147462)


   

Cys Asn Tyr Gly

2-[(2S)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-carbamoylpropanamido]-3-(4-hydroxyphenyl)propanamido]acetic acid

C18H25N5O7S (455.147462)


   

Cys Gln Cys Cys

(2R)-2-[(2R)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-4-carbamoylbutanamido]-3-sulfanylpropanamido]-3-sulfanylpropanoic acid

C14H25N5O6S3 (455.096691)


   

Cys Tyr Gly Asn

(2S)-2-{2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-(4-hydroxyphenyl)propanamido]acetamido}-3-carbamoylpropanoic acid

C18H25N5O7S (455.147462)


   

Cys Tyr Asn Gly

2-[(2S)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-(4-hydroxyphenyl)propanamido]-3-carbamoylpropanamido]acetic acid

C18H25N5O7S (455.147462)


   

Asp Ala His Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]propanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanoic acid

C17H25N7O8 (455.176453)


   

Asp Ala Asn His

(3S)-3-amino-3-{[(1S)-1-{[(1S)-2-carbamoyl-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}ethyl]carbamoyl}ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asp Gly His Gln

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-3-carboxypropanamido]acetamido}-3-(1H-imidazol-4-yl)propanamido]-4-carbamoylbutanoic acid

C17H25N7O8 (455.176453)


   

Asp Gly Gln His

(3S)-3-amino-3-[({[(1S)-3-carbamoyl-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propyl]carbamoyl}methyl)carbamoyl]propanoic acid

C17H25N7O8 (455.176453)


   

Asp His Ala Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-3-(1H-imidazol-4-yl)propanamido]propanamido]-3-carbamoylpropanoic acid

C17H25N7O8 (455.176453)


   

Asp His Gly Gln

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-3-(1H-imidazol-4-yl)propanamido]acetamido}-4-carbamoylbutanoic acid

C17H25N7O8 (455.176453)


   

Asp His Asn Ala

(3S)-3-amino-3-{[(1S)-1-{[(1S)-2-carbamoyl-1-{[(1S)-1-carboxyethyl]carbamoyl}ethyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asp His Gln Gly

(3S)-3-amino-3-{[(1S)-1-{[(1S)-3-carbamoyl-1-[(carboxymethyl)carbamoyl]propyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asp Asn Ala His

(3S)-3-amino-3-{[(1S)-2-carbamoyl-1-{[(1S)-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}ethyl]carbamoyl}ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asp Asn His Ala

(3S)-3-amino-3-{[(1S)-2-carbamoyl-1-{[(1S)-1-{[(1S)-1-carboxyethyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asp Gln Gly His

(3S)-3-amino-3-{[(1S)-3-carbamoyl-1-[({[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}methyl)carbamoyl]propyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asp Gln His Gly

(3S)-3-amino-3-{[(1S)-3-carbamoyl-1-{[(1S)-1-[(carboxymethyl)carbamoyl]-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Glu Gly His Asn

(4S)-4-amino-4-[({[(1S)-1-{[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}methyl)carbamoyl]butanoic acid

C17H25N7O8 (455.176453)


   

Glu Gly Asn His

(4S)-4-amino-4-[({[(1S)-2-carbamoyl-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}ethyl]carbamoyl}methyl)carbamoyl]butanoic acid

C17H25N7O8 (455.176453)


   

Glu His Gly Asn

(4S)-4-amino-4-{[(1S)-1-[({[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}methyl)carbamoyl]-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Glu His Asn Gly

(4S)-4-amino-4-{[(1S)-1-{[(1S)-2-carbamoyl-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Glu Asn Gly His

(4S)-4-amino-4-{[(1S)-2-carbamoyl-1-[({[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}methyl)carbamoyl]ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Glu Asn His Gly

(4S)-4-amino-4-{[(1S)-2-carbamoyl-1-{[(1S)-1-[(carboxymethyl)carbamoyl]-2-(1H-imidazol-4-yl)ethyl]carbamoyl}ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Gly Cys Asn Tyr

(2S)-2-[(2S)-2-[(2R)-2-(2-aminoacetamido)-3-sulfanylpropanamido]-3-carbamoylpropanamido]-3-(4-hydroxyphenyl)propanoic acid

C18H25N5O7S (455.147462)


   

Gly Cys Tyr Asn

(2S)-2-[(2S)-2-[(2R)-2-(2-aminoacetamido)-3-sulfanylpropanamido]-3-(4-hydroxyphenyl)propanamido]-3-carbamoylpropanoic acid

C18H25N5O7S (455.147462)


   

Gly Asp His Gln

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-carboxypropanamido]-3-(1H-imidazol-4-yl)propanamido]-4-carbamoylbutanoic acid

C17H25N7O8 (455.176453)


   

Gly Asp Gln His

(3S)-3-(2-aminoacetamido)-3-{[(1S)-3-carbamoyl-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Gly Glu His Asn

(4S)-4-(2-aminoacetamido)-4-{[(1S)-1-{[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Gly Glu Asn His

(4S)-4-(2-aminoacetamido)-4-{[(1S)-2-carbamoyl-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Gly His Asp Gln

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido]-3-carboxypropanamido]-4-carbamoylbutanoic acid

C17H25N7O8 (455.176453)


   

Gly His Glu Asn

(4S)-4-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido]-4-{[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Gly His Asn Glu

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]pentanedioic acid

C17H25N7O8 (455.176453)


   

Gly His Gln Asp

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido]-4-carbamoylbutanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

Gly Asn Cys Tyr

(2S)-2-[(2R)-2-[(2S)-2-(2-aminoacetamido)-3-carbamoylpropanamido]-3-sulfanylpropanamido]-3-(4-hydroxyphenyl)propanoic acid

C18H25N5O7S (455.147462)


   

Gly Asn Glu His

(4S)-4-[(2S)-2-(2-aminoacetamido)-3-carbamoylpropanamido]-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Gly Asn His Glu

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]pentanedioic acid

C17H25N7O8 (455.176453)


   

Gly Asn Tyr Cys

(2R)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-carbamoylpropanamido]-3-(4-hydroxyphenyl)propanamido]-3-sulfanylpropanoic acid

C18H25N5O7S (455.147462)


   

Gly Gln Asp His

(3S)-3-[(2S)-2-(2-aminoacetamido)-4-carbamoylbutanamido]-3-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Gly Gln His Asp

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-4-carbamoylbutanamido]-3-(1H-imidazol-4-yl)propanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

Gly Tyr Cys Asn

(2S)-2-[(2R)-2-[(2S)-2-(2-aminoacetamido)-3-(4-hydroxyphenyl)propanamido]-3-sulfanylpropanamido]-3-carbamoylpropanoic acid

C18H25N5O7S (455.147462)


   

Gly Tyr Asn Cys

(2R)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-(4-hydroxyphenyl)propanamido]-3-carbamoylpropanamido]-3-sulfanylpropanoic acid

C18H25N5O7S (455.147462)


   

His Ala Asp Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]propanamido]-3-carboxypropanamido]-3-carbamoylpropanoic acid

C17H25N7O8 (455.176453)


   

His Ala Asn Asp

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]propanamido]-3-carbamoylpropanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

His Asp Ala Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-carboxypropanamido]propanamido]-3-carbamoylpropanoic acid

C17H25N7O8 (455.176453)


   

His Asp Gly Gln

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-carboxypropanamido]acetamido}-4-carbamoylbutanoic acid

C17H25N7O8 (455.176453)


   

His Asp Asn Ala

(3S)-3-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-{[(1S)-2-carbamoyl-1-{[(1S)-1-carboxyethyl]carbamoyl}ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

His Asp Gln Gly

(3S)-3-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-{[(1S)-3-carbamoyl-1-[(carboxymethyl)carbamoyl]propyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

His Glu Gly Asn

(4S)-4-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-4-[({[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}methyl)carbamoyl]butanoic acid

C17H25N7O8 (455.176453)


   

His Glu Asn Gly

(4S)-4-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-4-{[(1S)-2-carbamoyl-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

His Gly Asp Gln

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}-3-carboxypropanamido]-4-carbamoylbutanoic acid

C17H25N7O8 (455.176453)


   

His Gly Glu Asn

(4S)-4-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}-4-{[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

His Gly Asn Glu

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}-3-carbamoylpropanamido]pentanedioic acid

C17H25N7O8 (455.176453)


   

His Gly Gln Asp

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}-4-carbamoylbutanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

His Asn Ala Asp

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]propanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

His Asn Asp Ala

(3S)-3-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]-3-{[(1S)-1-carboxyethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

His Asn Glu Gly

(4S)-4-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]-4-[(carboxymethyl)carbamoyl]butanoic acid

C17H25N7O8 (455.176453)


   

His Asn Gly Glu

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]acetamido}pentanedioic acid

C17H25N7O8 (455.176453)


   

His Gln Asp Gly

(3S)-3-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-4-carbamoylbutanamido]-3-[(carboxymethyl)carbamoyl]propanoic acid

C17H25N7O8 (455.176453)


   

His Gln Gly Asp

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-4-carbamoylbutanamido]acetamido}butanedioic acid

C17H25N7O8 (455.176453)


   

Lys Cys Cys Cys

(2R)-2-[(2R)-2-[(2R)-2-[(2S)-2,6-diaminohexanamido]-3-sulfanylpropanamido]-3-sulfanylpropanamido]-3-sulfanylpropanoic acid

C15H29N5O5S3 (455.13307440000005)


   

Asn Ala Asp His

(3S)-3-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]propanamido]-3-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asn Ala His Asp

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]propanamido]-3-(1H-imidazol-4-yl)propanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

Asn Cys Gly Tyr

(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-sulfanylpropanamido]acetamido}-3-(4-hydroxyphenyl)propanoic acid

C18H25N5O7S (455.147462)


   

Asn Cys Tyr Gly

2-[(2S)-2-[(2R)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-sulfanylpropanamido]-3-(4-hydroxyphenyl)propanamido]acetic acid

C18H25N5O7S (455.147462)


   

Asn Asp Ala His

(3S)-3-[(2S)-2-amino-3-carbamoylpropanamido]-3-{[(1S)-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asn Asp His Ala

(3S)-3-[(2S)-2-amino-3-carbamoylpropanamido]-3-{[(1S)-1-{[(1S)-1-carboxyethyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asn Glu Gly His

(4S)-4-[(2S)-2-amino-3-carbamoylpropanamido]-4-[({[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}methyl)carbamoyl]butanoic acid

C17H25N7O8 (455.176453)


   

Asn Glu His Gly

(4S)-4-[(2S)-2-amino-3-carbamoylpropanamido]-4-{[(1S)-1-[(carboxymethyl)carbamoyl]-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Asn Gly Cys Tyr

(2S)-2-[(2R)-2-{2-[(2S)-2-amino-3-carbamoylpropanamido]acetamido}-3-sulfanylpropanamido]-3-(4-hydroxyphenyl)propanoic acid

C18H25N5O7S (455.147462)


   

Asn Gly Glu His

(4S)-4-{2-[(2S)-2-amino-3-carbamoylpropanamido]acetamido}-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Asn Gly His Glu

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-3-carbamoylpropanamido]acetamido}-3-(1H-imidazol-4-yl)propanamido]pentanedioic acid

C17H25N7O8 (455.176453)


   

Asn Gly Tyr Cys

(2R)-2-[(2S)-2-{2-[(2S)-2-amino-3-carbamoylpropanamido]acetamido}-3-(4-hydroxyphenyl)propanamido]-3-sulfanylpropanoic acid

C18H25N5O7S (455.147462)


   

Asn His Ala Asp

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]propanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

Asn His Asp Ala

(3S)-3-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]-3-{[(1S)-1-carboxyethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asn His Glu Gly

(4S)-4-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]-4-[(carboxymethyl)carbamoyl]butanoic acid

C17H25N7O8 (455.176453)


   

Asn His Gly Glu

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]acetamido}pentanedioic acid

C17H25N7O8 (455.176453)


   

Asn Tyr Cys Gly

2-[(2R)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-(4-hydroxyphenyl)propanamido]-3-sulfanylpropanamido]acetic acid

C18H25N5O7S (455.147462)


   

Asn Tyr Gly Cys

(2R)-2-{2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-(4-hydroxyphenyl)propanamido]acetamido}-3-sulfanylpropanoic acid

C18H25N5O7S (455.147462)


   

Gln Cys Cys Cys

(2R)-2-[(2R)-2-[(2R)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-sulfanylpropanamido]-3-sulfanylpropanamido]-3-sulfanylpropanoic acid

C14H25N5O6S3 (455.096691)


   

Gln Asp Gly His

(3S)-3-[(2S)-2-amino-4-carbamoylbutanamido]-3-[({[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}methyl)carbamoyl]propanoic acid

C17H25N7O8 (455.176453)


   

Gln Asp His Gly

(3S)-3-[(2S)-2-amino-4-carbamoylbutanamido]-3-{[(1S)-1-[(carboxymethyl)carbamoyl]-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Gln Gly Asp His

(3S)-3-{2-[(2S)-2-amino-4-carbamoylbutanamido]acetamido}-3-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Gln Gly His Asp

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-4-carbamoylbutanamido]acetamido}-3-(1H-imidazol-4-yl)propanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

Gln His Asp Gly

(3S)-3-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-(1H-imidazol-4-yl)propanamido]-3-[(carboxymethyl)carbamoyl]propanoic acid

C17H25N7O8 (455.176453)


   

Gln His Gly Asp

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-(1H-imidazol-4-yl)propanamido]acetamido}butanedioic acid

C17H25N7O8 (455.176453)


   

Tyr Cys Gly Asn

(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-3-sulfanylpropanamido]acetamido}-3-carbamoylpropanoic acid

C18H25N5O7S (455.147462)


   

Tyr Cys Asn Gly

2-[(2S)-2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetic acid

C18H25N5O7S (455.147462)


   

Tyr Gly Cys Asn

(2S)-2-[(2R)-2-{2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]acetamido}-3-sulfanylpropanamido]-3-carbamoylpropanoic acid

C18H25N5O7S (455.147462)


   

Tyr Gly Asn Cys

(2R)-2-[(2S)-2-{2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]acetamido}-3-carbamoylpropanamido]-3-sulfanylpropanoic acid

C18H25N5O7S (455.147462)


   

Tyr Asn Cys Gly

2-[(2R)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-3-carbamoylpropanamido]-3-sulfanylpropanamido]acetic acid

C18H25N5O7S (455.147462)


   

Tyr Asn Gly Cys

(2R)-2-{2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-3-carbamoylpropanamido]acetamido}-3-sulfanylpropanoic acid

C18H25N5O7S (455.147462)


   

Indomethacin heptyl ester

1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid, 1-heptyl ester

C26H30ClNO4 (455.18632500000007)


   
   

N5,N10-Methenyltetrahydrofolic acid

N5,N10-Methenyltetrahydrofolic acid

C20H21N7O6 (455.15532460000003)


   

Tryptophol [xylosyl-(1->6)-glucoside]

2-[2-(1H-indol-3-yl)ethoxy]-6-{[(3,4,5-trihydroxyoxan-2-yl)oxy]methyl}oxane-3,4,5-triol

C21H29NO10 (455.17913740000006)


   

16-carboxy-Delta(13)-17,18,19,20-tetranor-N-acetyl-leukotriene E4

(5Z,7E,9E,11R,12S)-11-(N-acetyl-L-cystein-S-yl)-12-hydroxyhexadeca-3,5,7,9-tetraenedioic acid;(5Z,7E,9E,11R,12S)-11-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-12-hydroxyhexadeca-3,5,7,9-tetraenedioic acid

C21H29NO8S (455.16137940000004)


   

Methopterin

2-[[4-[(2-Amino-4-Oxo-1H-Pteridin-6-Yl)Methyl-Methylamino]Benzoyl]Amino]Pentanedioic Acid

C20H21N7O6 (455.15532460000003)


   

XL388

XL388

C23H22FN3O4S (455.13149840000005)


XL388 is a highly potent and ATP-competitive mTOR inhibitor with an IC50 of 9.9 nM. XL388 simultaneously inhibits both mTORC1 and mTORC2. XL388 is a highly potent and ATP-competitive mTOR inhibitor with an IC50 of 9.9 nM. XL388 simultaneously inhibits both mTORC1 and mTORC2.

   

2 5-BIS(CHLOROMETHYL)-1 4-BIS(BUTOXY)BE&

2 5-BIS(CHLOROMETHYL)-1 4-BIS(BUTOXY)BE&

C26H21N3O3S (455.13035560000003)


   

TETRAETHYLAMMONIUM TETRACHLOROMANGANATE&

TETRAETHYLAMMONIUM TETRACHLOROMANGANATE&

C16H40Cl4MnN2 (455.13259)


   

fmoc-(r)-3-amino-3-(3-trifluoromethyl-phenyl)-propionic acid

fmoc-(r)-3-amino-3-(3-trifluoromethyl-phenyl)-propionic acid

C25H20F3NO4 (455.1344356000001)


   

(2S)-3-amino-2-(9H-fluoren-9-ylmethoxycarbonyl)-4-(2,4,5-trifluorophenyl)butanoic acid

(2S)-3-amino-2-(9H-fluoren-9-ylmethoxycarbonyl)-4-(2,4,5-trifluorophenyl)butanoic acid

C25H20F3NO4 (455.1344356000001)


   
   

fmoc-(s)-3-amino-3-(3-trifluoromethyl-phenyl)-propionic acid

fmoc-(s)-3-amino-3-(3-trifluoromethyl-phenyl)-propionic acid

C25H20F3NO4 (455.1344356000001)


   

fmoc-(s)-3-amino-3-(4-trifluoromethyl-phenyl)-propionic acid

fmoc-(s)-3-amino-3-(4-trifluoromethyl-phenyl)-propionic acid

C25H20F3NO4 (455.1344356000001)


   

(R)-3-((((9H-FLUOREN-9-YL)METHOXY)CARBONYL)AMINO)-4-(2,4,5-TRIFLUOROPHENYL)BUTANOIC ACID

(R)-3-((((9H-FLUOREN-9-YL)METHOXY)CARBONYL)AMINO)-4-(2,4,5-TRIFLUOROPHENYL)BUTANOIC ACID

C25H20F3NO4 (455.1344356000001)


   
   

fmoc-(r)-3-amino-3-(4-trifluoromethyl-phenyl)-propionic acid

fmoc-(r)-3-amino-3-(4-trifluoromethyl-phenyl)-propionic acid

C25H20F3NO4 (455.1344356000001)


   
   

Methyl (E)-2-[3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoate

Methyl (E)-2-[3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoate

C28H22ClNO3 (455.1288132000001)


   

fmoc-(r)-3-amino-3-(2-trifluoromethyl-phenyl)-propionic acid

fmoc-(r)-3-amino-3-(2-trifluoromethyl-phenyl)-propionic acid

C25H20F3NO4 (455.1344356000001)


   

(2S)-2-[[(2S)-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-phenylpropanoic acid

(2S)-2-[[(2S)-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-phenylpropanoic acid

C20H29N3O5S2 (455.15485440000003)


   
   
   

2-(5-METHYL-2-((4-(2-(PYRROLIDIN-1-YL)ETHOXY)PHENYL)AMINO)PYRIMIDIN-4-YL)BENZO[B]THIOPHENE-5-CARBONITRILE

2-(5-METHYL-2-((4-(2-(PYRROLIDIN-1-YL)ETHOXY)PHENYL)AMINO)PYRIMIDIN-4-YL)BENZO[B]THIOPHENE-5-CARBONITRILE

C26H25N5OS (455.177972)


   

dimethyl (2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate

dimethyl (2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate

C22H25N5O6 (455.180475)


   

primaquine phosphate

primaquine phosphate

C15H27N3O9P2 (455.1222472)


D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C277 - Antiprotozoal Agent

   

Methyl 2-(3-{3-[2-(7-chloroquinolin-2-yl)vinyl]phenyl}-3-oxopropyl)benzoate

Methyl 2-(3-{3-[2-(7-chloroquinolin-2-yl)vinyl]phenyl}-3-oxopropyl)benzoate

C28H22ClNO3 (455.1288132000001)


   

Lisdexamfetamine dimesylate

(2S)-2,6-diamino-N-[(2S)-1-phenylpropan-2-yl]hexanamide,methanesulfonic acid

C17H33N3O7S2 (455.1759828)


D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant C78272 - Agent Affecting Nervous System > C29728 - Anorexiant D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D049990 - Membrane Transport Modulators

   

1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]-1-propanone

1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]-1-propanone

C29H26ClNO2 (455.16519660000006)


   

4,8-bis(thiophen-2-yl)-6-(2-ethylhexyl)-[1,2,5]thiadiazolo[3,4-f]benzotriazole

4,8-bis(thiophen-2-yl)-6-(2-ethylhexyl)-[1,2,5]thiadiazolo[3,4-f]benzotriazole

C22H25N5S3 (455.127201)


   

13H-spiro[benzo[c]indeno[2,1-a]carbazole-14,9-fluorene]

13H-spiro[benzo[c]indeno[2,1-a]carbazole-14,9-fluorene]

C35H21N (455.16739060000003)


   

fmoc-(s)-3-amino-3-(2-trifluoromethyl-phenyl)-propionic acid

fmoc-(s)-3-amino-3-(2-trifluoromethyl-phenyl)-propionic acid

C25H20F3NO4 (455.1344356000001)


   

Abt-639

Abt-639

C20H20ClF2N3O3S (455.08819040000003)


C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent > C333 - Calcium Channel Blocker C78272 - Agent Affecting Nervous System > C245 - Anesthetic Agent C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent C93038 - Cation Channel Blocker

   

N-(2-((4aR,6S,8aR)-2-Amino-6-methyl-4a,5,6,8-tetrahydro-4H-pyrano(3,4-d)(1,3)thiazin-8a-yl)thiazol-4-yl)-5-(difluoromethoxy)pyridine-2-carboxamide

N-(2-((4aR,6S,8aR)-2-Amino-6-methyl-4a,5,6,8-tetrahydro-4H-pyrano(3,4-d)(1,3)thiazin-8a-yl)thiazol-4-yl)-5-(difluoromethoxy)pyridine-2-carboxamide

C18H19F2N5O3S2 (455.08973280000004)


   
   

Moxifloxacin hydrochloride monohydrate

Moxifloxacin hydrochloride monohydrate

C21H27ClFN3O5 (455.16231740000006)


D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D024841 - Fluoroquinolones D004791 - Enzyme Inhibitors

   

Avarofloxacin hydrochloride

Avarofloxacin hydrochloride

C21H24ClF2N3O4 (455.1423318)


C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic

   
   

[2-[2-Morpholin-4-yl-5-(trifluoromethyl)anilino]-2-oxoethyl] 2-methylsulfanylpyridine-3-carboxylate

[2-[2-Morpholin-4-yl-5-(trifluoromethyl)anilino]-2-oxoethyl] 2-methylsulfanylpyridine-3-carboxylate

C20H20F3N3O4S (455.1126556000001)


   

N-(3,5-dimethylphenyl)-2-[(4-oxo-3-phenyl-2-benzofuro[3,2-d]pyrimidinyl)thio]acetamide

N-(3,5-dimethylphenyl)-2-[(4-oxo-3-phenyl-2-benzofuro[3,2-d]pyrimidinyl)thio]acetamide

C26H21N3O3S (455.13035560000003)


   

Allyl-{6-[3-(4-bromo-phenyl)-1-methyl-1H-indazol-6-YL]oxy}hexyl)-N-methylamine

Allyl-{6-[3-(4-bromo-phenyl)-1-methyl-1H-indazol-6-YL]oxy}hexyl)-N-methylamine

C24H30BrN3O (455.157211)


   

3-(2-Chlorophenyl)-1-(2-{[(1S)-2-hydroxy-1,2-dimethylpropyl]amino}pyrimidin-4-YL)-1-(4-methoxyphenyl)urea

3-(2-Chlorophenyl)-1-(2-{[(1S)-2-hydroxy-1,2-dimethylpropyl]amino}pyrimidin-4-YL)-1-(4-methoxyphenyl)urea

C23H26ClN5O3 (455.17240760000004)


   

{4-[2,2-Bis(5-methyl-1,2,4-oxadiazol-3-YL)-3-phenylpropyl]phenyl}sulfamic acid

{4-[2,2-Bis(5-methyl-1,2,4-oxadiazol-3-YL)-3-phenylpropyl]phenyl}sulfamic acid

C21H21N5O5S (455.12633360000007)


   

N-(3-Chlorophenyl)-N-Methyl-2-Oxo-3-[(3,4,5-Trimethyl-1h-Pyrrol-2-Yl)methyl]-2h-Indole-5-Sulfonamide

N-(3-Chlorophenyl)-N-Methyl-2-Oxo-3-[(3,4,5-Trimethyl-1h-Pyrrol-2-Yl)methyl]-2h-Indole-5-Sulfonamide

C23H22ClN3O3S (455.10703320000005)


   
   

Apafant

Apafant

C22H22ClN5O2S (455.11826620000005)


C78275 - Agent Affecting Blood or Body Fluid > C1327 - Antiplatelet Agent D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D006401 - Hematologic Agents > D005343 - Fibrinolytic Agents D050299 - Fibrin Modulating Agents D002317 - Cardiovascular Agents

   

Pradigastat

Pradigastat

C25H24F3N3O2 (455.182052)


C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent Pradigastat (LCQ-908) is a potent, selective and orally active diacylglycerol acyltransferase 1 (DGAT1) inhibitor. Pradigastat has anti-obesity and anti-diabetic effects[1][2].

   

N-Formylmethionyl-methionyl-phenylalanine

2-{[1-hydroxy-2-({1-hydroxy-2-[(hydroxymethylidene)amino]-4-(methylsulphanyl)butylidene}amino)-4-(methylsulphanyl)butylidene]amino}-3-phenylpropanoic acid

C20H29N3O5S2 (455.15485440000003)


   

(6R)-5,10-methylenetetrahydrofolate(2-)

(6R)-5,10-methylenetetrahydrofolate(2-)

C20H21N7O6-2 (455.15532460000003)


   

2-deoxy-5-keto-dihydrostreptosyl-K252c

2-deoxy-5-keto-dihydrostreptosyl-K252c

C26H21N3O5 (455.14811360000004)


   

(E)-1-(glutathion-S-yl)-N-hydroxy-2-(4-hydroxyphenyl)ethan-1-imine

(E)-1-(glutathion-S-yl)-N-hydroxy-2-(4-hydroxyphenyl)ethan-1-imine

C18H23N4O8S- (455.1236538)


   
   

2-[[4-(3-Amino-1-oxo-2,5,6,6a,7,9-hexahydroimidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioate

2-[[4-(3-Amino-1-oxo-2,5,6,6a,7,9-hexahydroimidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioate

C20H21N7O6-2 (455.15532460000003)


   
   

10-[3-[4-(2-Chloroethyl)-1-piperazinyl]propyl]-2-(trifluoromethyl)phenothiazine

10-[3-[4-(2-Chloroethyl)-1-piperazinyl]propyl]-2-(trifluoromethyl)phenothiazine

C22H25ClF3N3S (455.14097160000006)


   

3-(2-chlorophenyl)-5-methyl-N-[4-[2-(4-morpholinyl)-2-oxoethoxy]phenyl]-4-isoxazolecarboxamide

3-(2-chlorophenyl)-5-methyl-N-[4-[2-(4-morpholinyl)-2-oxoethoxy]phenyl]-4-isoxazolecarboxamide

C23H22ClN3O5 (455.12479120000006)


   

4-tert-butyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide

4-tert-butyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide

C19H19F6NO3S (455.0989776)


   

4-(2-amino-3-cyano-5-oxo-5,6,7,8-tetrahydro-4H-chromen-4-yl)-2,6-dimethoxyphenyl morpholine-4-carboxylate

4-(2-amino-3-cyano-5-oxo-5,6,7,8-tetrahydro-4H-chromen-4-yl)-2,6-dimethoxyphenyl morpholine-4-carboxylate

C23H25N3O7 (455.169242)


   

2-[4-Chloro-6-(4-phenylanilino)pyrimidin-2-yl]sulfanyloctanoic acid

2-[4-Chloro-6-(4-phenylanilino)pyrimidin-2-yl]sulfanyloctanoic acid

C24H26ClN3O2S (455.1434166000001)


   

Benzylpenicilloyl cysteine

Benzylpenicilloyl cysteine

C19H25N3O6S2 (455.118471)


   

2-[2-oxo-6-(1-pyrrolidinylsulfonyl)-1,3-benzoxazol-3-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

2-[2-oxo-6-(1-pyrrolidinylsulfonyl)-1,3-benzoxazol-3-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

C23H25N3O5S (455.15148400000004)


   

N,N-diethyl-3-[(4-fluorophenyl)sulfonylamino]-4-(1-pyrrolidinyl)benzenesulfonamide

N,N-diethyl-3-[(4-fluorophenyl)sulfonylamino]-4-(1-pyrrolidinyl)benzenesulfonamide

C20H26FN3O4S2 (455.13486880000005)


   

3,4-dimethoxy-N-[4-(2,2,3,3-tetrafluoropropoxy)-3-(trifluoromethyl)phenyl]benzamide

3,4-dimethoxy-N-[4-(2,2,3,3-tetrafluoropropoxy)-3-(trifluoromethyl)phenyl]benzamide

C19H16F7NO4 (455.09675000000004)


   

3-Benzoyl-1,5-bis(2-methoxyphenyl)-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-dione

3-Benzoyl-1,5-bis(2-methoxyphenyl)-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-dione

C26H21N3O5 (455.14811360000004)


   

N-(2-methoxyphenyl)-5-methyl-3-(1-naphthalenylmethyl)-4-oxo-6-thieno[2,3-d]pyrimidinecarboxamide

N-(2-methoxyphenyl)-5-methyl-3-(1-naphthalenylmethyl)-4-oxo-6-thieno[2,3-d]pyrimidinecarboxamide

C26H21N3O3S (455.13035560000003)


   

2-[[benzyl-[(2-fluorophenyl)methyl]carbamothioyl]amino]-N-[(4-chlorophenyl)methyl]acetamide

2-[[benzyl-[(2-fluorophenyl)methyl]carbamothioyl]amino]-N-[(4-chlorophenyl)methyl]acetamide

C24H23ClFN3OS (455.12343100000004)


   

2-[[4-(3,4-dimethylphenyl)-1-phenyl-2-imidazolyl]thio]-N-(1,1-dioxo-3-thiolanyl)acetamide

2-[[4-(3,4-dimethylphenyl)-1-phenyl-2-imidazolyl]thio]-N-(1,1-dioxo-3-thiolanyl)acetamide

C23H25N3O3S2 (455.13372599999997)


   

N-(1,3-benzodioxol-5-ylmethylene)-2-(2,4-dimethoxyphenyl)-4-quinolinecarbohydrazide

N-(1,3-benzodioxol-5-ylmethylene)-2-(2,4-dimethoxyphenyl)-4-quinolinecarbohydrazide

C26H21N3O5 (455.14811360000004)


   

N,N-diethyl-2-[[7-[(4-methoxyphenyl)methyl]-8-oxo-[1,3]dioxolo[4,5-g]quinazolin-6-yl]thio]acetamide

N,N-diethyl-2-[[7-[(4-methoxyphenyl)methyl]-8-oxo-[1,3]dioxolo[4,5-g]quinazolin-6-yl]thio]acetamide

C23H25N3O5S (455.15148400000004)


   

6-[(2-ethylphenyl)sulfamoyl]-4-oxo-N-(2-oxolanylmethyl)-1H-quinoline-3-carboxamide

6-[(2-ethylphenyl)sulfamoyl]-4-oxo-N-(2-oxolanylmethyl)-1H-quinoline-3-carboxamide

C23H25N3O5S (455.15148400000004)


   

8-Benzyl-2-hydroperoxy-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]imidazo[1,2-a]pyrazin-3-one

8-Benzyl-2-hydroperoxy-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]imidazo[1,2-a]pyrazin-3-one

C26H21N3O5 (455.14811360000004)


   
   
   
   

1-(3,5-dichlorophenyl)-3-[(2S,3R,6R)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea

1-(3,5-dichlorophenyl)-3-[(2S,3R,6R)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea

C20H27Cl2N5O3 (455.14908520000006)


   

1-(3,5-dichlorophenyl)-3-[(2S,3R,6S)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea

1-(3,5-dichlorophenyl)-3-[(2S,3R,6S)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea

C20H27Cl2N5O3 (455.14908520000006)


   

1-(3,5-dichlorophenyl)-3-[(2R,3S,6R)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea

1-(3,5-dichlorophenyl)-3-[(2R,3S,6R)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea

C20H27Cl2N5O3 (455.14908520000006)


   

1-(3,5-dichlorophenyl)-3-[(2R,3R,6R)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea

1-(3,5-dichlorophenyl)-3-[(2R,3R,6R)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea

C20H27Cl2N5O3 (455.14908520000006)


   

1-(3,5-dichlorophenyl)-3-[(2R,3S,6S)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea

1-(3,5-dichlorophenyl)-3-[(2R,3S,6S)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea

C20H27Cl2N5O3 (455.14908520000006)


   

1-(3,5-dichlorophenyl)-3-[(2S,3S,6S)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea

1-(3,5-dichlorophenyl)-3-[(2S,3S,6S)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea

C20H27Cl2N5O3 (455.14908520000006)


   

[(2R,3S,4S)-5-(7,8-dimethyl-2-oxido-4-oxo-3,5-dihydrobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] phosphate

[(2R,3S,4S)-5-(7,8-dimethyl-2-oxido-4-oxo-3,5-dihydrobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] phosphate

C17H20N4O9P-3 (455.096786)


   

2-[2-(3-methoxyphenyl)-2-oxoethyl]-N-[2-(3-methylphenyl)ethyl]-3-oxo-4H-quinoxaline-6-carboxamide

2-[2-(3-methoxyphenyl)-2-oxoethyl]-N-[2-(3-methylphenyl)ethyl]-3-oxo-4H-quinoxaline-6-carboxamide

C27H25N3O4 (455.184497)


   

2-amino-4-({1-[(carboxymethyl)-C-hydroxycarbonimidoyl]-2-[(1-hydroxy-3-oxo-1-phenylpropan-2-yl)sulfanyl]ethyl}-C-hydroxycarbonimidoyl)butanoic acid

2-amino-4-({1-[(carboxymethyl)-C-hydroxycarbonimidoyl]-2-[(1-hydroxy-3-oxo-1-phenylpropan-2-yl)sulfanyl]ethyl}-C-hydroxycarbonimidoyl)butanoic acid

C19H25N3O8S (455.136229)


   

2-amino-4-({1-[(carboxymethyl)-C-hydroxycarbonimidoyl]-2-{[1-(2-hydroxyphenyl)-3-oxopropyl]sulfanyl}ethyl}-C-hydroxycarbonimidoyl)butanoic acid

2-amino-4-({1-[(carboxymethyl)-C-hydroxycarbonimidoyl]-2-{[1-(2-hydroxyphenyl)-3-oxopropyl]sulfanyl}ethyl}-C-hydroxycarbonimidoyl)butanoic acid

C19H25N3O8S (455.136229)


   

(2S)-2-[[2-(3-hydroxy-5-oxo-4-phenylfuran-2-ylidene)-2-phenylacetyl]amino]-3-phenylpropanoic acid

(2S)-2-[[2-(3-hydroxy-5-oxo-4-phenylfuran-2-ylidene)-2-phenylacetyl]amino]-3-phenylpropanoic acid

C27H21NO6 (455.13688060000004)


   

4,7-DI(4-Methoxyphenyl)-6-(2-methoxyphenyl)-1,2,5-thiadiazolo(3,4-C)pyridine

4,7-DI(4-Methoxyphenyl)-6-(2-methoxyphenyl)-1,2,5-thiadiazolo(3,4-C)pyridine

C26H21N3O3S (455.13035560000003)


   

FMNH2(3-)

FMNH2(3-)

C17H20N4O9P (455.096786)


A organophosphate oxoanion obtained by deprotonation of the phosphate OH groups as well as position N1 of FMNH2.

   

(6R)-5,10-methylenetetrahydrofolate(2-)

(6R)-5,10-methylenetetrahydrofolate(2-)

C20H21N7O6 (455.15532460000003)


   
   

coelenterazine 2-hydroperoxide

coelenterazine 2-hydroperoxide

C26H21N3O5 (455.14811360000004)


A member of the class of oxidized luciferins that is obtained via formal hydroperoxidation at position 2 of Oplophorus luciferin.

   
   
   

AD57

AD57

C22H20F3N7O (455.16813460000003)


AD57 is an orally active multikinase inhibitor, inhibits RET, BRAF, S6K and Src, with greatly reduces mTOR activity[1].

   

GNE-9815

GNE-9815

C26H22FN5O2 (455.1757444)


GNE-9815 (compound 7) is a highly selective, pan-RAF inhibitor with good oral bioavailability. GNE-9815 exhibits Ki values of 0.062 and 0.19 nM for CRAF and BRAF, respectively. GNE-9815 combines with MEK inhibitor Cobimetinib (HY-13064) shows synergistic modulation of MAPK pathway. GNE-9815 can be used in studies of KRAS mutant cancers[1].

   

(1s,6r,10r,12r,19s,20r,21s)-21-(dimethylamino)-16,20-dihydroxy-12,19-dimethyl-7,11,23-trioxahexacyclo[17.3.1.0²,¹⁸.0³,¹⁵.0⁵,¹³.0⁶,¹⁰]tricosa-2,5(13),15,17-tetraene-4,8,14-trione

(1s,6r,10r,12r,19s,20r,21s)-21-(dimethylamino)-16,20-dihydroxy-12,19-dimethyl-7,11,23-trioxahexacyclo[17.3.1.0²,¹⁸.0³,¹⁵.0⁵,¹³.0⁶,¹⁰]tricosa-2,5(13),15,17-tetraene-4,8,14-trione

C24H25NO8 (455.158009)


   

(2r,4r,5s,6s)-4-methyl-3-oxa-1,7,17-triazaoctacyclo[12.12.2.1²,⁶.0⁷,²⁸.0⁸,¹³.0¹⁵,¹⁹.0²⁰,²⁷.0²¹,²⁶]nonacosa-8(13),9,11,14(28),15(19),17,20(27),21(26),22,24-decaene-5,6,18,23-tetrol

(2r,4r,5s,6s)-4-methyl-3-oxa-1,7,17-triazaoctacyclo[12.12.2.1²,⁶.0⁷,²⁸.0⁸,¹³.0¹⁵,¹⁹.0²⁰,²⁷.0²¹,²⁶]nonacosa-8(13),9,11,14(28),15(19),17,20(27),21(26),22,24-decaene-5,6,18,23-tetrol

C26H21N3O5 (455.14811360000004)


   

[(2r,3r,4r,5s,6r)-2-{[(2s,3r,4r,5r,6s)-4,5-dihydroxy-2-{[(2s)-1-hydroxy-3-oxopropan-2-yl]oxy}-6-methyloxan-3-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]amino acetate

[(2r,3r,4r,5s,6r)-2-{[(2s,3r,4r,5r,6s)-4,5-dihydroxy-2-{[(2s)-1-hydroxy-3-oxopropan-2-yl]oxy}-6-methyloxan-3-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]amino acetate

C17H29NO13 (455.16388240000003)


   

[2-({4,5-dihydroxy-2-[(1-hydroxy-3-oxopropan-2-yl)oxy]-6-methyloxan-3-yl}oxy)-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]amino acetate

[2-({4,5-dihydroxy-2-[(1-hydroxy-3-oxopropan-2-yl)oxy]-6-methyloxan-3-yl}oxy)-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]amino acetate

C17H29NO13 (455.16388240000003)


   

26-(1,2-dihydroxyethyl)-4,24-dihydroxy-25-oxa-16-azahexacyclo[15.7.2.0¹,²⁶.0²,¹⁵.0⁵,¹⁴.0⁷,¹²]hexacosa-2,4,7,9,11,14,20-heptaen-18,22-diyne-6,13-dione

26-(1,2-dihydroxyethyl)-4,24-dihydroxy-25-oxa-16-azahexacyclo[15.7.2.0¹,²⁶.0²,¹⁵.0⁵,¹⁴.0⁷,¹²]hexacosa-2,4,7,9,11,14,20-heptaen-18,22-diyne-6,13-dione

C26H17NO7 (455.1004972)


   

14-methoxy-10-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,5-dioxa-10-azapentacyclo[9.7.1.0²,⁶.0⁸,¹⁹.0¹³,¹⁸]nonadeca-1(19),2(6),7,11,13(18),14,16-heptaen-9-one

14-methoxy-10-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,5-dioxa-10-azapentacyclo[9.7.1.0²,⁶.0⁸,¹⁹.0¹³,¹⁸]nonadeca-1(19),2(6),7,11,13(18),14,16-heptaen-9-one

C23H21NO9 (455.1216256)