Exact Mass: 455.13688060000004
Exact Mass Matches: 455.13688060000004
Found 231 metabolites which its exact mass value is equals to given mass value 455.13688060000004
,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
5,10-Methenyltetrahydrofolic acid
C20H21N7O6 (455.15532460000003)
Folate is important for cells and tissues that rapidly divide. Cancer cells divide rapidly, and drugs that interfere with folate metabolism are used to treat cancer. Methotrexate is a drug often used to treat cancer because it inhibits the production of the active form, tetrahydrofolate. Unfortunately, methotrexate can be toxic, producing side effects such as inflammation in the digestive tract that make it difficult to eat normally. Folinic acid is a form of folate that can help rescue or reverse the toxic effects of methotrexate. Folinic acid is not the same as folic acid. Folic acid supplements have little established role in cancer chemotherapy. There have been cases of severe adverse effects of accidental substitution of folic acid for folinic acid in patients receiving methotrexate cancer chemotherapy. It is important for anyone receiving methotrexate to follow medical advice on the use of folic or folinic acid supplements. Low concentrations of folate, vitamin B12, or vitamin B6 may increase your level of homocysteine, an amino acid normally found in your blood. There is evidence that an elevated homocysteine level is an independent risk factor for heart disease and stroke. The evidence suggests that high levels of homocysteine may damage coronary arteries or make it easier for blood clotting cells called platelets to clump together and form a clot. However, there is currently no evidence available to suggest that lowering homocysteine with vitamins will reduce your risk of heart disease. Clinical intervention trials are needed to determine whether supplementation with folic acid, vitamin B12 or vitamin B6 can lower your risk of developing coronary heart disease. Methylene tetrahydrofolate (CH2FH4) is formed from tetrahydrofolate by the addition of methylene groups from one of three carbon donors: formaldehyde, serine, or glycine. Methyl tetrahydrofolate(CH3FH4) can be made from methylene tetrahydrofolate by reduction of the methylene group, and formyl tetrahydrofolate (CHOFH4, folinic acid) is made by oxidation of methylene tetrahydrofolate. In the form of a series of tetrahydrofolate compounds, folate derivatives are substrates in a number of single-carbon-transfer reactions, and also are involved in the synthesis of dTMP (2-deoxythymidine-5-phosphate) from dUMP (2-deoxyuridine-5-phosphate). It helps convert vitamin B12 to one of its coenzyme forms and helps synthesize the DNA required for all rapidly growing cells.
Tryptophol [xylosyl-(1->6)-glucoside]
C21H29NO10 (455.17913740000006)
Tryptophol [xylosyl-(1->6)-glucoside] is found in coffee and coffee products. Tryptophol [xylosyl-(1->6)-glucoside] is isolated from Lycium chinense (Chinese boxthom). Isolated from Lycium chinense (Chinese boxthom). Tryptophol [xylosyl-(1->6)-glucoside] is found in tea, coffee and coffee products, and herbs and spices.
(4S)-4-[[4-(3-Amino-1-oxo-5,6,6a,7-tetrahydro-2H-imidazo[1,5-f]pteridin-10-ium-8-yl)benzoyl]amino]-5-hydroxy-5-oxopentanoate
C20H21N7O6 (455.15532460000003)
Apafant
C22H22ClN5O2S (455.11826620000005)
C78275 - Agent Affecting Blood or Body Fluid > C1327 - Antiplatelet Agent D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D006401 - Hematologic Agents > D005343 - Fibrinolytic Agents D050299 - Fibrin Modulating Agents D002317 - Cardiovascular Agents
N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(6-methyl-2-oxo-3-phenylmethanesulfonylamino-2H-pyridin-1-yl)-acetamide
C22H25N5O4S (455.16271700000004)
Clevidipine
C - Cardiovascular system > C08 - Calcium channel blockers > C08C - Selective calcium channel blockers with mainly vascular effects > C08CA - Dihydropyridine derivatives C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent > C333 - Calcium Channel Blocker D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators C93038 - Cation Channel Blocker
N-Formylmethionyl-methionyl-phenylalanine
C20H29N3O5S2 (455.15485440000003)
N-Pyridazin-3-yl-4-[[3-[5-(trifluoromethyl)pyridin-2-yl]oxyphenyl]methylidene]piperidine-1-carboxamide
Redafamdastat (PF-04457845) is a highly efficacious and selective FAAH inhibitor with IC50 values is 7.2±0.63 nM and 7.4±0.62 nM for hFAAH and rFAAH, respectively.
Pradigastat
C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent Pradigastat (LCQ-908) is a potent, selective and orally active diacylglycerol acyltransferase 1 (DGAT1) inhibitor. Pradigastat has anti-obesity and anti-diabetic effects[1][2].
2-[[4-[(2-Amino-4-oxo-3H-pteridin-6-yl)methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid
C20H21N7O6 (455.15532460000003)
2-[[4-[(2-Amino-4-oxo-3H-pteridin-6-yl)methylamino]benzoyl]amino]-4-methylpentanedioic acid
C20H21N7O6 (455.15532460000003)
5-O-(Butanoyloxymethyl) 3-O-methyl (4R)-4-(2,3-dichlorophenyl)-2,6-dimethyl-3,4-dihydropyridine-3,5-dicarboxylate
5,10-methylenetetrahydrofolate
C20H21N7O6 (455.15532460000003)
5,10-methylenetetrahydrofolate is slightly soluble (in water) and a weakly acidic compound (based on its pKa). 5,10-methylenetetrahydrofolate can be found in a number of food items such as yellow bell pepper, mexican groundcherry, celery leaves, and hard wheat, which makes 5,10-methylenetetrahydrofolate a potential biomarker for the consumption of these food products. The diastereoisomer [6R]-5,10-methylene-THF is the key endogenous one-carbon donor and a co-substrate of the TS (thymidylate synthase) enzyme for methylation of 2-deoxy-uridine-5-monophosphate (dUMP) to 2-deoxy-thymidine-5-monophosphate (dTMP). The coenzyme is necessary for the biosynthesis of thymidine and is the C1-donor in the reactions catalyzed by TS and thymidylate synthase (FAD) .
N13-1-beta-L-digitoxosylarcyriaflavin
C26H21N3O5 (455.14811360000004)
Ala Asn His Asp
Clevidipine
C - Cardiovascular system > C08 - Calcium channel blockers > C08C - Selective calcium channel blockers with mainly vascular effects > C08CA - Dihydropyridine derivatives C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent > C333 - Calcium Channel Blocker D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators C93038 - Cation Channel Blocker
Ala Asp His Asn
Ala Asp Asn His
Ala His Asp Asn
Ala His Asn Asp
Ala Asn Asp His
Cys Cys Cys Lys
C15H29N5O5S3 (455.13307440000005)
Cys Cys Cys Gln
Cys Cys Lys Cys
C15H29N5O5S3 (455.13307440000005)
Cys Cys Gln Cys
Cys Gly Asn Tyr
Cys Gly Tyr Asn
Cys Lys Cys Cys
C15H29N5O5S3 (455.13307440000005)
Cys Asn Gly Tyr
Cys Asn Tyr Gly
Cys Gln Cys Cys
Cys Tyr Gly Asn
Cys Tyr Asn Gly
Asp Ala His Asn
Asp Ala Asn His
Asp Gly His Gln
Asp Gly Gln His
Asp His Ala Asn
Asp His Gly Gln
Asp His Asn Ala
Asp His Gln Gly
Asp Asn Ala His
Asp Asn His Ala
Asp Gln Gly His
Asp Gln His Gly
Glu Gly His Asn
Glu Gly Asn His
Glu His Gly Asn
Glu His Asn Gly
Glu Asn Gly His
Glu Asn His Gly
Gly Cys Asn Tyr
Gly Cys Tyr Asn
Gly Asp His Gln
Gly Asp Gln His
Gly Glu His Asn
Gly Glu Asn His
Gly His Asp Gln
Gly His Glu Asn
Gly His Asn Glu
Gly His Gln Asp
Gly Asn Cys Tyr
Gly Asn Glu His
Gly Asn His Glu
Gly Asn Tyr Cys
Gly Gln Asp His
Gly Gln His Asp
Gly Tyr Cys Asn
Gly Tyr Asn Cys
His Ala Asp Asn
His Ala Asn Asp
His Asp Ala Asn
His Asp Gly Gln
His Asp Asn Ala
His Asp Gln Gly
His Glu Gly Asn
His Glu Asn Gly
His Gly Asp Gln
His Gly Glu Asn
His Gly Asn Glu
His Gly Gln Asp
His Asn Ala Asp
His Asn Asp Ala
His Asn Glu Gly
His Asn Gly Glu
His Gln Asp Gly
His Gln Gly Asp
Lys Cys Cys Cys
C15H29N5O5S3 (455.13307440000005)
Asn Ala Asp His
Asn Ala His Asp
Asn Cys Gly Tyr
Asn Cys Tyr Gly
Asn Asp Ala His
Asn Asp His Ala
Asn Glu Gly His
Asn Glu His Gly
Asn Gly Cys Tyr
Asn Gly Glu His
Asn Gly His Glu
Asn Gly Tyr Cys
Asn His Ala Asp
Asn His Asp Ala
Asn His Glu Gly
Asn His Gly Glu
Asn Tyr Cys Gly
Asn Tyr Gly Cys
Gln Cys Cys Cys
Gln Asp Gly His
Gln Asp His Gly
Gln Gly Asp His
Gln Gly His Asp
Gln His Asp Gly
Gln His Gly Asp
Tyr Cys Gly Asn
Tyr Cys Asn Gly
Tyr Gly Cys Asn
Tyr Gly Asn Cys
Tyr Asn Cys Gly
Tyr Asn Gly Cys
Indomethacin heptyl ester
C26H30ClNO4 (455.18632500000007)
N5,N10-Methenyltetrahydrofolic acid
C20H21N7O6 (455.15532460000003)
Tryptophol [xylosyl-(1->6)-glucoside]
C21H29NO10 (455.17913740000006)
16-carboxy-Delta(13)-17,18,19,20-tetranor-N-acetyl-leukotriene E4
C21H29NO8S (455.16137940000004)
Methopterin
C20H21N7O6 (455.15532460000003)
XL388
C23H22FN3O4S (455.13149840000005)
XL388 is a highly potent and ATP-competitive mTOR inhibitor with an IC50 of 9.9 nM. XL388 simultaneously inhibits both mTORC1 and mTORC2. XL388 is a highly potent and ATP-competitive mTOR inhibitor with an IC50 of 9.9 nM. XL388 simultaneously inhibits both mTORC1 and mTORC2.
2 5-BIS(CHLOROMETHYL)-1 4-BIS(BUTOXY)BE&
C26H21N3O3S (455.13035560000003)
fmoc-(r)-3-amino-3-(3-trifluoromethyl-phenyl)-propionic acid
C25H20F3NO4 (455.1344356000001)
(2S)-3-amino-2-(9H-fluoren-9-ylmethoxycarbonyl)-4-(2,4,5-trifluorophenyl)butanoic acid
C25H20F3NO4 (455.1344356000001)
fmoc-(s)-3-amino-3-(3-trifluoromethyl-phenyl)-propionic acid
C25H20F3NO4 (455.1344356000001)
fmoc-(s)-3-amino-3-(4-trifluoromethyl-phenyl)-propionic acid
C25H20F3NO4 (455.1344356000001)
(R)-3-((((9H-FLUOREN-9-YL)METHOXY)CARBONYL)AMINO)-4-(2,4,5-TRIFLUOROPHENYL)BUTANOIC ACID
C25H20F3NO4 (455.1344356000001)
fmoc-(r)-3-amino-3-(4-trifluoromethyl-phenyl)-propionic acid
C25H20F3NO4 (455.1344356000001)
Methyl (E)-2-[3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoate
C28H22ClNO3 (455.1288132000001)
fmoc-(r)-3-amino-3-(2-trifluoromethyl-phenyl)-propionic acid
C25H20F3NO4 (455.1344356000001)
(2S)-2-[[(2S)-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-phenylpropanoic acid
C20H29N3O5S2 (455.15485440000003)
2-(5-METHYL-2-((4-(2-(PYRROLIDIN-1-YL)ETHOXY)PHENYL)AMINO)PYRIMIDIN-4-YL)BENZO[B]THIOPHENE-5-CARBONITRILE
dimethyl (2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate
primaquine phosphate
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C277 - Antiprotozoal Agent
Methyl 2-(3-{3-[2-(7-chloroquinolin-2-yl)vinyl]phenyl}-3-oxopropyl)benzoate
C28H22ClNO3 (455.1288132000001)
Lisdexamfetamine dimesylate
D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant C78272 - Agent Affecting Nervous System > C29728 - Anorexiant D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D049990 - Membrane Transport Modulators
1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]-1-propanone
C29H26ClNO2 (455.16519660000006)
4,8-bis(thiophen-2-yl)-6-(2-ethylhexyl)-[1,2,5]thiadiazolo[3,4-f]benzotriazole
13H-spiro[benzo[c]indeno[2,1-a]carbazole-14,9-fluorene]
fmoc-(s)-3-amino-3-(2-trifluoromethyl-phenyl)-propionic acid
C25H20F3NO4 (455.1344356000001)
Abt-639
C20H20ClF2N3O3S (455.08819040000003)
C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent > C333 - Calcium Channel Blocker C78272 - Agent Affecting Nervous System > C245 - Anesthetic Agent C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent C93038 - Cation Channel Blocker
N-(2-((4aR,6S,8aR)-2-Amino-6-methyl-4a,5,6,8-tetrahydro-4H-pyrano(3,4-d)(1,3)thiazin-8a-yl)thiazol-4-yl)-5-(difluoromethoxy)pyridine-2-carboxamide
C18H19F2N5O3S2 (455.08973280000004)
Moxifloxacin hydrochloride monohydrate
C21H27ClFN3O5 (455.16231740000006)
D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D024841 - Fluoroquinolones D004791 - Enzyme Inhibitors
Avarofloxacin hydrochloride
C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic
5,10-Methylenetetrahydrofolate(2-)
C20H21N7O6-2 (455.15532460000003)
[2-[2-Morpholin-4-yl-5-(trifluoromethyl)anilino]-2-oxoethyl] 2-methylsulfanylpyridine-3-carboxylate
C20H20F3N3O4S (455.1126556000001)
N-(3,5-dimethylphenyl)-2-[(4-oxo-3-phenyl-2-benzofuro[3,2-d]pyrimidinyl)thio]acetamide
C26H21N3O3S (455.13035560000003)
Allyl-{6-[3-(4-bromo-phenyl)-1-methyl-1H-indazol-6-YL]oxy}hexyl)-N-methylamine
3-(2-Chlorophenyl)-1-(2-{[(1S)-2-hydroxy-1,2-dimethylpropyl]amino}pyrimidin-4-YL)-1-(4-methoxyphenyl)urea
C23H26ClN5O3 (455.17240760000004)
{4-[2,2-Bis(5-methyl-1,2,4-oxadiazol-3-YL)-3-phenylpropyl]phenyl}sulfamic acid
C21H21N5O5S (455.12633360000007)
N-(3-Chlorophenyl)-N-Methyl-2-Oxo-3-[(3,4,5-Trimethyl-1h-Pyrrol-2-Yl)methyl]-2h-Indole-5-Sulfonamide
C23H22ClN3O3S (455.10703320000005)
Apafant
C22H22ClN5O2S (455.11826620000005)
C78275 - Agent Affecting Blood or Body Fluid > C1327 - Antiplatelet Agent D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D006401 - Hematologic Agents > D005343 - Fibrinolytic Agents D050299 - Fibrin Modulating Agents D002317 - Cardiovascular Agents
Pradigastat
C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent Pradigastat (LCQ-908) is a potent, selective and orally active diacylglycerol acyltransferase 1 (DGAT1) inhibitor. Pradigastat has anti-obesity and anti-diabetic effects[1][2].
N-Formylmethionyl-methionyl-phenylalanine
C20H29N3O5S2 (455.15485440000003)
(6R)-5,10-methylenetetrahydrofolate(2-)
C20H21N7O6-2 (455.15532460000003)
2-deoxy-5-keto-dihydrostreptosyl-K252c
C26H21N3O5 (455.14811360000004)
(E)-1-(glutathion-S-yl)-N-hydroxy-2-(4-hydroxyphenyl)ethan-1-imine
2-[[4-(3-Amino-1-oxo-2,5,6,6a,7,9-hexahydroimidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioate
C20H21N7O6-2 (455.15532460000003)
(Rs)-5,10-methenyltetrahydrofolate
C20H21N7O6 (455.15532460000003)
10-[3-[4-(2-Chloroethyl)-1-piperazinyl]propyl]-2-(trifluoromethyl)phenothiazine
C22H25ClF3N3S (455.14097160000006)
3-(2-chlorophenyl)-5-methyl-N-[4-[2-(4-morpholinyl)-2-oxoethoxy]phenyl]-4-isoxazolecarboxamide
C23H22ClN3O5 (455.12479120000006)
4-tert-butyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
4-(2-amino-3-cyano-5-oxo-5,6,7,8-tetrahydro-4H-chromen-4-yl)-2,6-dimethoxyphenyl morpholine-4-carboxylate
2-[4-Chloro-6-(4-phenylanilino)pyrimidin-2-yl]sulfanyloctanoic acid
C24H26ClN3O2S (455.1434166000001)
2-[2-oxo-6-(1-pyrrolidinylsulfonyl)-1,3-benzoxazol-3-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide
C23H25N3O5S (455.15148400000004)
N,N-diethyl-3-[(4-fluorophenyl)sulfonylamino]-4-(1-pyrrolidinyl)benzenesulfonamide
C20H26FN3O4S2 (455.13486880000005)
3,4-dimethoxy-N-[4-(2,2,3,3-tetrafluoropropoxy)-3-(trifluoromethyl)phenyl]benzamide
C19H16F7NO4 (455.09675000000004)
3-Benzoyl-1,5-bis(2-methoxyphenyl)-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-dione
C26H21N3O5 (455.14811360000004)
N-(2-methoxyphenyl)-5-methyl-3-(1-naphthalenylmethyl)-4-oxo-6-thieno[2,3-d]pyrimidinecarboxamide
C26H21N3O3S (455.13035560000003)
2-[[benzyl-[(2-fluorophenyl)methyl]carbamothioyl]amino]-N-[(4-chlorophenyl)methyl]acetamide
C24H23ClFN3OS (455.12343100000004)
2-[[4-(3,4-dimethylphenyl)-1-phenyl-2-imidazolyl]thio]-N-(1,1-dioxo-3-thiolanyl)acetamide
C23H25N3O3S2 (455.13372599999997)
N-(1,3-benzodioxol-5-ylmethylene)-2-(2,4-dimethoxyphenyl)-4-quinolinecarbohydrazide
C26H21N3O5 (455.14811360000004)
N,N-diethyl-2-[[7-[(4-methoxyphenyl)methyl]-8-oxo-[1,3]dioxolo[4,5-g]quinazolin-6-yl]thio]acetamide
C23H25N3O5S (455.15148400000004)
6-[(2-ethylphenyl)sulfamoyl]-4-oxo-N-(2-oxolanylmethyl)-1H-quinoline-3-carboxamide
C23H25N3O5S (455.15148400000004)
8-Benzyl-2-hydroperoxy-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]imidazo[1,2-a]pyrazin-3-one
C26H21N3O5 (455.14811360000004)
1-(3,5-dichlorophenyl)-3-[(2S,3R,6R)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea
C20H27Cl2N5O3 (455.14908520000006)
1-(3,5-dichlorophenyl)-3-[(2S,3R,6S)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea
C20H27Cl2N5O3 (455.14908520000006)
1-(3,5-dichlorophenyl)-3-[(2R,3S,6R)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea
C20H27Cl2N5O3 (455.14908520000006)
1-(3,5-dichlorophenyl)-3-[(2R,3R,6R)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea
C20H27Cl2N5O3 (455.14908520000006)
1-(3,5-dichlorophenyl)-3-[(2R,3S,6S)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea
C20H27Cl2N5O3 (455.14908520000006)
1-(3,5-dichlorophenyl)-3-[(2S,3S,6S)-2-(hydroxymethyl)-6-[2-(4-propan-2-yl-1-triazolyl)ethyl]-3-oxanyl]urea
C20H27Cl2N5O3 (455.14908520000006)
[(2R,3S,4S)-5-(7,8-dimethyl-2-oxido-4-oxo-3,5-dihydrobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] phosphate
2-[2-(3-methoxyphenyl)-2-oxoethyl]-N-[2-(3-methylphenyl)ethyl]-3-oxo-4H-quinoxaline-6-carboxamide
2-amino-4-({1-[(carboxymethyl)-C-hydroxycarbonimidoyl]-2-[(1-hydroxy-3-oxo-1-phenylpropan-2-yl)sulfanyl]ethyl}-C-hydroxycarbonimidoyl)butanoic acid
2-amino-4-({1-[(carboxymethyl)-C-hydroxycarbonimidoyl]-2-{[1-(2-hydroxyphenyl)-3-oxopropyl]sulfanyl}ethyl}-C-hydroxycarbonimidoyl)butanoic acid
(2S)-2-[[2-(3-hydroxy-5-oxo-4-phenylfuran-2-ylidene)-2-phenylacetyl]amino]-3-phenylpropanoic acid
C27H21NO6 (455.13688060000004)
4,7-DI(4-Methoxyphenyl)-6-(2-methoxyphenyl)-1,2,5-thiadiazolo(3,4-C)pyridine
C26H21N3O3S (455.13035560000003)
FMNH2(3-)
A organophosphate oxoanion obtained by deprotonation of the phosphate OH groups as well as position N1 of FMNH2.
(6R)-5,10-methylenetetrahydrofolate(2-)
C20H21N7O6 (455.15532460000003)
5,10-Methylenetetrahydrofolate(2-)
C20H21N7O6 (455.15532460000003)
coelenterazine 2-hydroperoxide
C26H21N3O5 (455.14811360000004)
A member of the class of oxidized luciferins that is obtained via formal hydroperoxidation at position 2 of Oplophorus luciferin.
AD57
C22H20F3N7O (455.16813460000003)
AD57 is an orally active multikinase inhibitor, inhibits RET, BRAF, S6K and Src, with greatly reduces mTOR activity[1].
GNE-9815
GNE-9815 (compound 7) is a highly selective, pan-RAF inhibitor with good oral bioavailability. GNE-9815 exhibits Ki values of 0.062 and 0.19 nM for CRAF and BRAF, respectively. GNE-9815 combines with MEK inhibitor Cobimetinib (HY-13064) shows synergistic modulation of MAPK pathway. GNE-9815 can be used in studies of KRAS mutant cancers[1].
(1s,6r,10r,12r,19s,20r,21s)-21-(dimethylamino)-16,20-dihydroxy-12,19-dimethyl-7,11,23-trioxahexacyclo[17.3.1.0²,¹⁸.0³,¹⁵.0⁵,¹³.0⁶,¹⁰]tricosa-2,5(13),15,17-tetraene-4,8,14-trione
(2r,4r,5s,6s)-4-methyl-3-oxa-1,7,17-triazaoctacyclo[12.12.2.1²,⁶.0⁷,²⁸.0⁸,¹³.0¹⁵,¹⁹.0²⁰,²⁷.0²¹,²⁶]nonacosa-8(13),9,11,14(28),15(19),17,20(27),21(26),22,24-decaene-5,6,18,23-tetrol
C26H21N3O5 (455.14811360000004)
[(2r,3r,4r,5s,6r)-2-{[(2s,3r,4r,5r,6s)-4,5-dihydroxy-2-{[(2s)-1-hydroxy-3-oxopropan-2-yl]oxy}-6-methyloxan-3-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]amino acetate
C17H29NO13 (455.16388240000003)
[2-({4,5-dihydroxy-2-[(1-hydroxy-3-oxopropan-2-yl)oxy]-6-methyloxan-3-yl}oxy)-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]amino acetate
C17H29NO13 (455.16388240000003)