Exact Mass: 436.13694039999996

Exact Mass Matches: 436.13694039999996

Found 500 metabolites which its exact mass value is equals to given mass value 436.13694039999996, within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error 0.01 dalton.

Phlorizin

1-{6-[(2S,4S,5S,3R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)(2H-3,4,5,6-tetrahydr opyran-2-yloxy)]-2,4-dihydroxyphenyl}-3-(4-hydroxyphenyl)propan-1-one

C21H24O10 (436.1369404)

Phlorizin, also known as phlorizoside or phlorrhizen, belongs to the class of organic compounds known as flavonoid o-glycosides. Flavonoid O-glycosides are compounds containing a carbohydrate moiety which is O-glycosidically linked to the 2-phenylchromen-4-one flavonoid backbone. Phlorizin (also referred to as phloridzin; chemical name phloretin-2-‚âà√≠‚Äö√¢¬ß-D-glucopyranoside) is a glucoside of phloretin, a dihydrochalcone, a family of bicyclic flavonoids, which in turn is a subgroup in the diverse phenylpropanoid synthesis pathway in plants. In humans, phlorizin is involved in lactose degradation. Phlorizin is a bitter tasting compound. phlorizin is found, on average, in the highest concentration in a few different foods, such as mexican oregano, european plums, and apples and in a lower concentration in pomegranates and apricots. phlorizin has also been detected, but not quantified, in several different foods, such as epazotes, durians, chinese broccoli, sesames, and sweet potato. This could make phlorizin a potential biomarker for the consumption of these foods. It is of sweet taste and contains four molecules of water in the crystal. Phlorizin is found primarily in unripe Malus (apple), root bark of apple, trace amounts have been found in strawberry. It is poorly soluble in ether and cold water, but soluble in ethanol and hot water. Closely related species, such as pear (Pyrus communis), cherry, and other fruit trees in the Rosaceae do not contain phloridzin. Phlorizin was studied as a potential pharmaceutical treatment for type 2 diabetes, but has since been superseded by more selective and more promising synthetic analogs, such as empagliflozin, canagliflozin and dapagliflozin. Phlorizin is a competitive inhibitor of SGLT1 and SGLT2 because it competes with D-glucose for binding to the carrier; this reduces renal glucose transport, lowering the amount of glucose in the blood. Phlorizin is not an effective drug because when orally consumed, it is nearly entirely converted into phloretin by hydrolytic enzymes in the small intestine. Above 200 °C, it decomposes. Phlorizin is an aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 2 via a glycosidic linkage. It has a role as a plant metabolite and an antioxidant. It is an aryl beta-D-glucoside, a member of dihydrochalcones and a monosaccharide derivative. It is functionally related to a phloretin. Phlorizin is a natural product found in Malus doumeri, Vaccinium macrocarpon, and other organisms with data available. See also: ... View More ... An aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 2 via a glycosidic linkage. Isolated from apple leaves and bark Phlorizin (Floridzin) is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor. Phlorizin (Floridzin) is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor.

Sanggenon A

(3R,11S)-7,11,14-trihydroxy-18,18-dimethyl-3-(3-methylbut-2-enyl)-2,10,19-trioxapentacyclo[11.8.0.03,11.04,9.015,20]henicosa-1(13),4(9),5,7,14,16,20-heptaen-12-one

C25H24O7 (436.1521954)

Sanggenon A is a member of chromenes. sanggenon A is a natural product found in Morus cathayana, Morus mongolica, and Morus alba with data available.

E-3174

2-butyl-4-chloro-1-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazole-5-carboxylic acid

C22H21ClN6O2 (436.1414436)

EXP3174 is a metabolite of losartan (previous name DuP753), which is a non-peptide angiotensin II receptor antagonist. EXP3174, a metabolite of losartan (MK 954, DuP 753) is more potent than losartan in blocking the angiotensin II-induced responses in vascular smooth muscle cells. (PMID: 8385175) D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure[1][2][3][4].

Tianeptine

7-[(6-chloro-10-methyl-9,9-dioxo-9$l^{6}-thia-10-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-2-yl)amino]heptanoic acid

C21H25ClN2O4S (436.12234800000004)

D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent N - Nervous system > N06 - Psychoanaleptics > N06A - Antidepressants Tianeptine is a selective facilitator of 5-HT uptake. Tianeptine has no affinity for a wide range of receptors, including 5-HT and dopamine (IC50>10 μM) and has no effect on noradrenalin or dopamine uptake. Tianeptine has antidepressant, anxiolytic, analgesic and neuroprotective activities[1][2][3][4].

Tianeptine

7-({6-chloro-10-methyl-9,9-dioxo-9λ⁶-thia-10-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3(8),4,6,11,13-hexaen-2-yl}amino)heptanoic acid

C21H25ClN2O4S (436.12234800000004)

Tianeptine (INN) was discovered by The French Society of Medical Research in the 1960s. Under the trade-names (Stablon, Coaxil, Tatinol) it is a drug used for treating major depressive episodes (mild, moderate, or severe). It has structural similarities to the tricyclic antidepressants, but it has different pharmacological properties. Tianeptine is a selective serotonin reuptake enhancer (SSRE), opposite to the action of SSRIs. One review points to the cancellative effects of tianeptine and fluoxetine coadministration on serotonin reuptake. Another suggests that long-term administration of tianeptine has no effect on serotonin pathways. Tianeptine enhances the extracellular concentration of dopamine in the nucleus accumbens and modulates the D2 and D3 dopamine receptors, but this effect is modest and almost certainly indirect. There is also action on the NMDA and AMPA receptors. Recent reviews point to this pathway as a hypothesized mechanism of action, based on tianeptines effect of reversing impaired neuroplasticity associated with stress. D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent N - Nervous system > N06 - Psychoanaleptics > N06A - Antidepressants Tianeptine is a selective facilitator of 5-HT uptake. Tianeptine has no affinity for a wide range of receptors, including 5-HT and dopamine (IC50>10 μM) and has no effect on noradrenalin or dopamine uptake. Tianeptine has antidepressant, anxiolytic, analgesic and neuroprotective activities[1][2][3][4].

Artonin J

6,8,17,19-tetrahydroxy-14,14-dimethyl-18-(3-methylbut-2-en-1-yl)-3,15-dioxapentacyclo[11.6.1.0²,¹¹.0⁴,⁹.0¹⁶,²⁰]icosa-1(20),2(11),4,6,8,16,18-heptaen-10-one

C25H24O7 (436.1521954)

Artonin J is found in fruits. Artonin J is a constituent of the root bark of Artocarpus heterophyllus (jackfruit). Constituent of the root bark of Artocarpus heterophyllus (jackfruit). Artonin J is found in jackfruit and fruits.

(-)-Epigallocatechin 3-cinnamate

(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl (2E)-3-phenylprop-2-enoate

C24H20O8 (436.115812)

(-)-Epigallocatechin 3-cinnamate is found in tea. (-)-Epigallocatechin 3-cinnamate is isolated from Assam tea (Camellia sinensis var. assamica). Isolated from Assam tea (Camellia sinensis variety assamica). Epigallocatechin 3-cinnamate is found in tea.

Trilobatin

1-(2,6-dihydroxy-4-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)-3-(4-hydroxyphenyl)propan-1-one

C21H24O10 (436.13694039999996)

Trilobatin is found in pomes. Trilobatin is isolated from apple leaves. Isolated from apple leaves. Trilobatin is found in pomes. Trilobatin, a natural sweetener derived from?Lithocarpus polystachyus?Rehd[1], Trilobatin?is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope[2]. Neuroprotective effects[1]. Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells[3]. Trilobatin, a natural sweetener derived from?Lithocarpus polystachyus?Rehd[1], Trilobatin?is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope[2]. Neuroprotective effects[1]. Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells[3].

Artonin E

5-Hydroxy-8,8-dimethyl-3-(3-methyl-2-butenyl)-2-(2,4,5-trihydroxyphenyl)-4H,8H-benzo[1,2-b:3,4-b]dipyran-4-one

C25H24O7 (436.1521954)

Artonin E is found in breadfruit. Artonin E is a constituent of Artocarpus communis (breadfruit). Constituent of Artocarpus communis (breadfruit). Artonin E is found in breadfruit and fruits.

Albanin B

2-(2,4-dihydroxyphenyl)-5-hydroxy-8-(hydroxymethyl)-8-methyl-3-(3-methylbut-2-en-1-yl)-4H,8H-pyrano[2,3-h]chromen-4-one

C25H24O7 (436.1521954)

Albanin B is found in fruits. Albanin B is isolated from Morus alba (white mulberry) infected with Fusarium solani. Isolated from Morus alba (white mulberry) infected with Fusarium solani. Albanin B is found in fruits.

Phenethyl 6-galloylglucoside

[3,4,5-Trihydroxy-6-(2-phenylethoxy)oxan-2-yl]methyl 3,4,5-trihydroxybenzoic acid

C21H24O10 (436.13694039999996)

Phenethyl 6-galloylglucoside is found in green vegetables. Phenethyl 6-galloylglucoside is isolated from Rosa damascena (damask rose Isolated from Rosa damascena (damask rose). Phenethyl 6-galloylglucoside is found in herbs and spices and green vegetables.

Bis-(1,3-diethylthiobarbituric acid)trimethine oxonol

5-[3-(1,3-Diethyl-4,6-dioxo-2-sulphanylidene-1,3-diazinan-5-ylidene)prop-1-en-1-yl]-1,3-diethyl-2-sulphanylidene-1,3-diazinane-4,6-dione

C19H24N4O4S2 (436.1238904)

Ertugliflozin

5-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

C22H25ClO7 (436.128873)

METESIND

N9-methyl-N9-{[4-(morpholine-4-sulfonyl)phenyl]methyl}-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(12),2,4,6,8,10-hexaene-3,9-diamine

C23H24N4O3S (436.15690340000003)

C471 - Enzyme Inhibitor > C2021 - Thymidylate Synthase Inhibitor

Nothofagin

3-(4-hydroxyphenyl)-1-{2,4,6-trihydroxy-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl}propan-1-one

C21H24O10 (436.13694039999996)

Phlorizine

1-(2,4-dihydroxy-6-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)-3-(4-hydroxyphenyl)propan-1-one

C21H24O10 (436.13694039999996)

Phlorizin (Floridzin) is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor. Phlorizin (Floridzin) is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor.

1-Propanone, 1-(3-beta-D-glucopyranosyl-2,4-dihydroxyphenyl)-3-hydroxy-3-(4-hydroxyphenyl)-

1-{2,4-dihydroxy-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl}-3-hydroxy-3-(4-hydroxyphenyl)propan-1-one

C21H24O10 (436.13694039999996)

Trilobatin

1-(2,6-dihydroxy-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-3-(4-hydroxyphenyl)propan-1-one

C21H24O10 (436.13694039999996)

Trilobatin is an aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 4 via a glycosidic linkage. It is isolated from the leaves of the Chinese sweet tea Lithocarpus polystachyus and exhibits significant anti-hyperglycemic, anti-oxidative and anti-inflammatory properties. It has a role as an anti-inflammatory agent, a sweetening agent, an antioxidant and a plant metabolite. It is an aryl beta-D-glucoside, a member of dihydrochalcones and a monosaccharide derivative. It is functionally related to a phloretin. Trilobatin is a natural product found in Malus trilobata, Balanophora tobiracola, and other organisms with data available. An aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 4 via a glycosidic linkage. It is isolated from the leaves of the Chinese sweet tea Lithocarpus polystachyus and exhibits significant anti-hyperglycemic, anti-oxidative and anti-inflammatory properties. Trilobatin, a natural sweetener derived from?Lithocarpus polystachyus?Rehd[1], Trilobatin?is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope[2]. Neuroprotective effects[1]. Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells[3]. Trilobatin, a natural sweetener derived from?Lithocarpus polystachyus?Rehd[1], Trilobatin?is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope[2]. Neuroprotective effects[1]. Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells[3].

Coatline A

4,2,4,alpha-Tetrahydroxy-3-C-glucopyranosyl-dihydrochalcone

C21H24O10 (436.13694039999996)

Broussonol B

8,9-Dihydro-3,5-dihydroxy-2- (8-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl) -8,9,9-trimethyl-4H-furo [ 2,3-h ] -1-benzopyran-4-one

C25H24O7 (436.1521954)

Melithiazol I

C21H28N2O4S2 (436.1490408)

Lupinisoflavone L

C25H24O7 (436.1521954)

Euchretin F

C25H24O7 (436.1521954)

MLS000697561

C25H24O7 (436.1521954)

Epiafzelechin 5-O-beta-D-glucopyranoside

(2R,3R) -3,5,7,4-Tetrahydroxyflavan 5-O-beta-D-glucopyranoside

C21H24O10 (436.13694039999996)

Alpigenoside

C18H28O12 (436.1580688)

Kraussianone 5

C25H24O7 (436.1521954)

Ent-afzelechin-7-O-beta-D-glucopyranoside

(2S,3R) -3,5,7,4-Tetrahydroxyflavan 7-O-beta-D-glucopyranoside

C21H24O10 (436.13694039999996)

9,10-Dihydro-10-(4-hydroxyphenyl)-pyrano[2,3-h]epicatechin-8-one

9,10-Dihydro-10- (4-hydroxyphenyl) -pyrano [ 2,3-h ] epicatechin-8-one

C24H20O8 (436.115812)

Kraussianone 7

5,7,2-Trihydroxy-6-(2-hydroxy-3-methyl-3-butenyl)-6,6-dimethylpyrano[2,3:4,3]isoflavone

C25H24O7 (436.1521954)

Kielcorin

C24H20O8 (436.115812)

Catechin 3-rhamnoside

(2R,3S) -3,5,7,3,4-Pentahydroxyflavan 3-O-alpha-L-rhamnoside

C21H24O10 (436.13694039999996)

3,8-Bis(3-methoxy-4-hydroxyphenyl)-3,3a,8,8a-tetrahydro-1H-indeno[1,2-c]furan-5,7-diol

C25H24O7 (436.1521954)

Eleganoside C

C18H28O12 (436.1580688)

Sanggenon M

(7aS,12bR) -7a,12b-Dihydro-6,7a,10-trihydroxy-3,3-dimethyl-12b- (3-methyl-2-butenyl) -3H,7H-benzofuro [ 3,2-b ] pyrano [ 2,3-h ] [ 1 ] benzopyran-7-one

C25H24O7 (436.1521954)

Nothofagin

1-[3-[(2S,3R,4R,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-2,4,6-tris(oxidanyl)phenyl]-3-(4-hydroxyphenyl)propan-1-one

C21H24O10 (436.13694039999996)

Nothofagin is a natural product found in Aspalathus linearis with data available.

Kraussianone 6

5,2,5-Trihydroxy-4,5-dihydro-(2,3:7,6),(2,3:4,3)-bis(6,6-dimethylpyrano)isoflavone

C25H24O7 (436.1521954)

Epiafzelechin 3-O-beta-D-allopyranoside

2- [ 5,7-dihydroxy-2- (4-hydroxyphenyl) chroman-3-yl ] oxy-6- (hydroxymethyl) oxane-3,4,5-triol

C21H24O10 (436.13694039999996)

Erysenegalensein L

5,2,4-Trihydroxy-8-(2-hydroxy-3-methyl-3-butenyl)-6,6-dimethylpyrano[2,3:7,6]isoflavone

C25H24O7 (436.1521954)

Afzelechin 4-O-beta-D-glucopyranosdie

(2R,3S) -2alpha- [ 4- (beta-D-Glucopyranosyloxy) phenyl ] -3,4-dihydro-2H-1-benzopyran-3,5,7-triol

C21H24O10 (436.13694039999996)

Foliosone

C24H20O8 (436.115812)

Erysenegalensein F

5,2,4-Trihydroxy-8-(2,3-epoxy-3-methylbutyl)-6,6-dimethylpyrano[2,3

C25H24O7 (436.1521954)

Tjipanazole C3

C24H21ClN2O4 (436.11897760000005)

Petalopurpurenol

(-) -3,5,7-Trihydroxy-2- [ 8-hydroxy-2-methyl-2- (4-methyl-3-pentenyl) -2H-1-benzopyran-5-yl ] -4H-1-benzopyran-4-one

C25H24O7 (436.1521954)

Vittarin F

C25H24O7 (436.1521954)

Tjipanazole C4

C24H21ClN2O4 (436.11897760000005)

Hydrangea glucoside B

C21H24O10 (436.13694039999996)

UCE-6

C24H20O8 (436.115812)

Licoagroside F

4,2,4,alpha-Tetrahydroxydihydrochalcone alpha-O-glucoside

C21H24O10 (436.13694039999996)

UGONIN M

C25H24O7 (436.1521954)

Artochamin E

C25H24O7 (436.1521954)

Falconensin L

C22H25ClO7 (436.128873)

2-(1-Hydroxy-1-methylethyl)-3-hydroxy-2,3-dihydrofuranoalpinumisoflavone

C25H24O7 (436.1521954)

Monnieraside III

C21H24O10 (436.13694039999996)

Catechin 7-O-alpha-L-rhamnopyranoside

C21H24O10 (436.13694039999996)

Lupinisoflavone K

C25H24O7 (436.1521954)

Euchretin L

5,7,5-Trihydroxy-8-prenyl-6,6-dimethyl-4,5-dihydropyrano[2,3:4,3]coumaronochromone

C25H24O7 (436.1521954)

CHEMBL4174882

C25H24O7 (436.1521954)

Daldinin D

C21H24O10 (436.13694039999996)

ugonin O

C25H24O7 (436.1521954)

Proximicin C

C22H20N4O6 (436.138278)

Falconensin N

C22H25ClO7 (436.128873)

Broussonol A

8- (1,1-Dimethyl-2-propenyl) -3,5,7-trihydroxy-2- (8-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl) -4H-1-benzopyran-4-one

C25H24O7 (436.1521954)

Macrophyllol A (flavone)

5-Hydroxy-7,8-dimethoxy-6- (2-hydroxy-5-methoxybenzyl) flavanone

C25H24O7 (436.1521954)

Epiafzelechin 3-O-beta-D-glucopyranoside

C21H24O10 (436.13694039999996)

Artobilichromene

5,2,4,5-Tetrahydroxy-6",6"-dimethyl-3-prenylpyrano [ 2",3":7,6 ] flavone

C25H24O7 (436.1521954)

Euchretin B

5,7,4,5-Tetrahydroxy-8,3-diprenylcoumaronochromone

C25H24O7 (436.1521954)

Artonin E

5-Hydroxy-8,8-dimethyl-3- (3-methyl-2-butenyl) -2- (2,4,5-trihydroxyphenyl) -4H,8H-benzo [ 1,2-b:3,4-b ] dipyran-4-one

C25H24O7 (436.1521954)

Artonin J

5a,6-Dihydro-1,3,8,10-tetrahydroxy-5,5-dimethyl-2- (3-methyl-2-butenyl) -5H,7H-benzofuro [ 3,4-bc ] xanthen-7-one

C25H24O7 (436.1521954)

Pterosupin

beta,2,4,4-Tetrahydroxy-3- (beta-D-glucopyranosyl) -alpha,beta-dihydrochalcone

C21H24O10 (436.13694039999996)

Epigallocatechin 3-O-cinnamate

(2R,3R) -3,5,7,3,4,5-Hexahydroxyflavan 3-O-cinnamate

C24H20O8 (436.115812)

Rocymosin B

4,2,4,beta-Tetrahydroxydihydrochalcone 2-glucoside

C21H24O10 (436.13694039999996)

SCHEMBL8170896

C23H24N4O3S (436.15690340000003)

Dihydrostilbene base + 3O, 1carboxy, O-Hex

C21H24O10 (436.13694039999996)

Annotation level-3

1-(2,4-dihydroxyphenyl)-3-hydroxy-3-(4-hydroxyphenyl-4-O-beta-D-glucopyranoside)-1-propanone

C21H24O10 (436.13694039999996)

luteoliflavan 5-beta-D-glucopyranoside

C21H24O10 (436.13694039999996)

Repenoside

C18H28O12 (436.1580688)

5-demethoxycadensin G

C24H20O8 (436.115812)

3-O-beta-D-glucopyranosyl-1,3,4-trihydroxy-5-methoxy-alpha-phenylstyrene

C21H24O10 (436.13694039999996)

melithiazol G

C21H28N2O4S2 (436.1490408)

Kielcorin B

C24H20O8 (436.115812)

1-(2,4-dihydroxyphenyl-4-O-beta-D-glucopyranoside)-3-hydroxy-3-(4-hydroxyphenyl)-1-propanone

C21H24O10 (436.13694039999996)

psoralidin oxide diacetate

C24H20O8 (436.115812)

4-O-beta-D-glucopyranosylbenzyl vanilloate|amburoside B

C21H24O10 (436.13694039999996)

7a,10a-dihydro-5-hydroxy-8,8-dimethyl-6-(2-methyl-1-oxobutyl)-4-phenyl-2H,8H-benzo[1,2]dioxolano[4,5:4,5]furo[2,3:5,6]benzo[1,2-b]pyran-2-one|mammea A/AB dioxalanocyclo E|Mammea A/AB dioxalanocyclo F

C25H24O7 (436.1521954)

Homaloside B

C21H24O10 (436.13694039999996)

(-)-Epiafzelechin 7-O-beta-D-glucopyranoside

C21H24O10 (436.13694039999996)

Rhizoferrin

C16H24N2O12 (436.1329184)

Tephroapollin G

C25H24O7 (436.1521954)

Artochamin B

C25H24O7 (436.1521954)

1-keto-3,10-epoxy-8beta-O-methacryloyl-4,15-dihydroxy-5-acetoxy-2,11-germacradiene, 6alpha,12-olide

C21H24O10 (436.13694039999996)

C25H24O7

C25H24O7 (436.1521954)

Butlerin C

C25H24O7 (436.1521954)

Cyathoviridin

C25H24O7 (436.1521954)

Catechin 3-O-alpha-L-rhamnopyranoside

C21H24O10 (436.13694039999996)

3-(3,4-Dihydroxyphenyl)-5-hydroxy-6-(2-hydroxy-3-methyl-3-butenyl)-8,8-dimethyl-4H,8H-benzo[1,2-b:3,4-b]dipyran-4-one

C25H24O7 (436.1521954)

Macrophyllin

C25H24O7 (436.1521954)

dihydromonospermoside

C21H24O10 (436.13694039999996)

SCHEMBL14006898

C25H24O7 (436.1521954)

eranthin beta-D-glucopyranoside

C21H24O10 (436.13694039999996)

NSC623323

C21H24O10 (436.13694039999996)

3-C-glucosylphloretin

C21H24O10 (436.13694039999996)

3,4-dihydro-10-hydroxy-7-methoxy-3-(R)-methyl-1H-3,4-dihydronaphtho-<2,3c>-pyran-1-one-9-O-beta-D-glucopyranoside|3,4-dihydro-10-hydroxy-7-methoxy-3-(R)-methyl-1H-3,4-dihydronaphtho-[2,3c]-pyran-1-one-9-O-beta-D-glucopyranoside

3,4-dihydro-10-hydroxy-7-methoxy-3-(R)-methyl-1H-3,4-dihydronaphtho-<2,3c>-pyran-1-one-9-O-beta-D-glucopyranoside|3,4-dihydro-10-hydroxy-7-methoxy-3-(R)-methyl-1H-3,4-dihydronaphtho-[2,3c]-pyran-1-one-9-O-beta-D-glucopyranoside

C21H24O10 (436.13694039999996)

Propinqualin

C21H24O10 (436.13694039999996)

artobiloxanthone

C25H24O7 (436.1521954)

Glochicoccin D

C21H24O10 (436.13694039999996)

2,4 dihydroxyphenyl-[6-O-(3-hydroxy,3-phenyl propanoyl)]-O-beta-D-allopyranoside

C21H24O10 (436.13694039999996)

C24H20O8

C24H20O8 (436.115812)

Millewanin E

C25H24O7 (436.1521954)

3,4,4,5,5-Pentamethoxy-(2,3-oxydibenzoic acid dimethyl) ester

C21H24O10 (436.13694039999996)

Isofoliosone

C24H20O8 (436.115812)

quassidine G

C26H20N4O3 (436.15353300000004)

(2R,6aS,11bR)-6a,11b-dihydro-5,6a,9-trihydroxy-2-(1-methylethenyl)-11b-(3-methyl-2-buten-1-yl)-1H,2H,6H-benzofuro[3,2-b]pyrano[2,3-g][1]-benzofuro-6-one|(2S,6aS,11bR)-6a,11b-dihydro-5,6a,9-trihydroxy-2-(1-methylethenyl)-11b-(3-methyl-2-buten-1-yl)-1H,2H,6H-benzofuro[3,2-b]pyrano[2,3-g][1]-benzofuro-6-one|nigrasin E|nigrasin F

(2R*,6aS,11bR)-6a,11b-dihydro-5,6a,9-trihydroxy-2-(1-methylethenyl)-11b-(3-methyl-2-buten-1-yl)-1H,2H,6H-benzofuro[3,2-b]pyrano[2,3-g][1]-benzofuro-6-one|(2S*,6aS,11bR)-6a,11b-dihydro-5,6a,9-trihydroxy-2-(1-methylethenyl)-11b-(3-methyl-2-buten-1-yl)-1H,2H,6H-benzofuro[3,2-b]pyrano[2,3-g][1]-benzofuro-6-one|nigrasin E|nigrasin F

C25H24O7 (436.1521954)

artosimmin

C25H24O7 (436.1521954)

3-deoxyurdamycinone B|JBIR-90

C25H24O7 (436.1521954)

2-(4-hydroxyphenyl)-3,4,9,10-tetrahydro-3,5-dihydroxy-10-(3,4-dihydroxyphenyl)-(2R,3R,10R)-2H,8H-benzo [1,2-b:3,4-b]dipyran-8-one|2-(4-hydroxyphenyl)-3,4,9,10-tetrahydro-3,5-dihydroxy-10-(3,4-dihydroxyphenyl)-(2R,3R,10R)-2H,8H-benzo[1,2-b:3,4-b]dipyran-8-one|corbulain Ia

2-(4-hydroxyphenyl)-3,4,9,10-tetrahydro-3,5-dihydroxy-10-(3,4-dihydroxyphenyl)-(2R,3R,10R)-2H,8H-benzo [1,2-b:3,4-b]dipyran-8-one|2-(4-hydroxyphenyl)-3,4,9,10-tetrahydro-3,5-dihydroxy-10-(3,4-dihydroxyphenyl)-(2R,3R,10R)-2H,8H-benzo[1,2-b:3,4-b]dipyran-8-one|corbulain Ia

C24H20O8 (436.115812)

7-acetoxy-8-[3-acetoxy-2,2-dimethyltetrahydro-4-furanyl]flavone|terpurinflavone

C25H24O7 (436.1521954)

cleidbrevoid A

C22H28O7S (436.15556580000003)

CHEMBL4452871

C25H24O7 (436.1521954)

(2R,3S)-2-(4-hydroxy-3,5-dimethoxyphenyl)-2,3,5,6-tetrahydrophenanthro[2,1-b]pyran-3,8,11-triol|chrysotoxol B

C25H24O7 (436.1521954)

SCHEMBL16018587

C20H24N2O9 (436.1481734)

schoepfin D

C21H24O10 (436.13694039999996)

3-(3-hydroxy-5-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-2H-[1,4]dioxino[2,3-c]xanthen-7(3H)-one|hypericorin B

C24H20O8 (436.115812)

trigoxyphin J

C25H24O7 (436.1521954)

furanocyclocommunin

C25H24O7 (436.1521954)

monnieriside F

C21H24O10 (436.13694039999996)

2-[3-(3,4-dihydroxyphenyl)propanoyl]-3,5-dihydroxyphenyl alpha-L-rhamnopyranoside|3-hydroxyphloretin 2-alpha-O-L-rhamnopyranoside|glycyphyllin B

C21H24O10 (436.13694039999996)

cineroside A

C21H24O10 (436.13694039999996)

C21H24O10

C21H24O10 (436.13694039999996)

3-hydroxymethyl-2-(3-hydroxy-4-methoxyphenyl)-5,6:5,6-(7-methoxyxanthone)-1,4-dioxane|hyperielliptone HD

C24H20O8 (436.115812)

Chromanoartobilochromene a

C25H24O7 (436.1521954)

3-hydroxyphlorhizin D-glucoside

C21H24O10 (436.13694039999996)

2-(5,8-dihydroxy-2,2-dimethyl-chroman-6-yl)-5-hydroxy-8,8-dimethyl-8H-pyrano[3,2-g]chromen-4-one|Chromanoartobilochromene b

C25H24O7 (436.1521954)

Neriaphin

C21H24O10 (436.13694039999996)

melithiazol N

C20H24N2O5S2 (436.1126574)

Neoranflaven-diacetat

C25H24O7 (436.1521954)

methyl 2,2-di O-methyleriodermate

C22H25ClO7 (436.128873)

ethylidene-aloenin

C21H24O10 (436.13694039999996)

NEOCYCLOMORUSIN

C25H24O7 (436.1521954)

2,6-dimethoxy-4-hydroxyphenyl 3-hydroxyphenyl ketone 3-O-beta-glucopyranoside|triptephenoside

C21H24O10 (436.13694039999996)

12a-Acetoxyisomilleton

C24H20O8 (436.115812)

Trp Glu Cys

C19H24N4O6S (436.1416484)

indol-3-ylmethyl-glutathione

C19H24N4O6S (436.1416484)

Epicatechin O-hexoside derivative

C21H24O10 (436.13694039999996)

Phlorizin

1-[2,4-dihydroxy-6-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy]phenyl]-3-(4-hydroxyphenyl)propan-1-one

C21H24O10 (436.13694039999996)

Origin: Plant; Formula(Parent): C21H24O10; Bottle Name:Phloridzin; PRIME Parent Name:Phloretin-2-O-glucoside; PRIME in-house No.:S0307, Glycosides relative retention time with respect to 9-anthracene Carboxylic Acid is 0.718 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.713 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.714 Acquisition and generation of the data is financially supported by the Max-Planck-Society IPB_RECORD: 2021; CONFIDENCE confident structure Phlorizin (Floridzin) is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor. Phlorizin (Floridzin) is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor.

1-[2,4-dihydroxy-3-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]-2-hydroxy-3-(4-hydroxyphenyl)propan-1-one

NCGC00385502-01!1-[2,4-dihydroxy-3-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]-2-hydroxy-3-(4-hydroxyphenyl)propan-1-one

C21H24O10 (436.13694039999996)

NCGC00347619-02!

C25H24O7 (436.1521954)

C21H24O10_(2S,3R)-3,5-Dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-yl beta-D-threo-hexopyranoside

NCGC00384633-01_C21H24O10_(2S,3R)-3,5-Dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-yl beta-D-threo-hexopyranoside

C21H24O10 (436.13694039999996)

EXP 3174

Losartan carboxylic acid [EXP3174]

C22H21ClN6O2 (436.1414436)

A biphenylyltetrazole that is losartan with the hydroxymethyl group at position 5 on the imidazole ring replaced with a carboxylic acid. D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure[1][2][3][4].

Phlorhizin

C21H24O10 (436.13694039999996)

1-[2,4-dihydroxy-3-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]-2-hydroxy-3-(4-hydroxyphenyl)propan-1-one

C21H24O10 (436.13694039999996)

3,7,21-trihydroxy-17,17-dimethyl-14-(3-methylbut-2-en-1-yl)-10,12,16-trioxapentacyclo[11.8.0.0³,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(13),4(9),5,7,14,18,20-heptaen-2-one

C25H24O7 (436.1521954)

Phloretin-2-O-glucoside

C21H24O10 (436.13694039999996)

Annotation level-1

Phloridzin

C21H24O10 (436.13694039999996)

1-[2,4-dihydroxy-3-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]-2-hydroxy-3-(4-hydroxyphenyl)propan-1-one [IIN-based: Match]

NCGC00385502-01!1-[2,4-dihydroxy-3-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]-2-hydroxy-3-(4-hydroxyphenyl)propan-1-one [IIN-based: Match]

C21H24O10 (436.13694039999996)

3,7,21-trihydroxy-17,17-dimethyl-14-(3-methylbut-2-en-1-yl)-10,12,16-trioxapentacyclo[11.8.0.0³,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(13),4(9),5,7,14,18,20-heptaen-2-one_35.3\\%

C25H24O7 (436.1521954)

Phlorhizin_major

C21H24O10 (436.13694039999996)

1-[2,4-dihydroxy-3-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]-2-hydroxy-3-(4-hydroxyphenyl)propan-1-one_major

C21H24O10 (436.13694039999996)

3,7,21-trihydroxy-17,17-dimethyl-14-(3-methylbut-2-en-1-yl)-10,12,16-trioxapentacyclo[11.8.0.0³,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(13),4(9),5,7,14,18,20-heptaen-2-one_major

C25H24O7 (436.1521954)

3,7,21-trihydroxy-17,17-dimethyl-14-(3-methylbut-2-en-1-yl)-10,12,16-trioxapentacyclo[11.8.0.0³,¹¹.0?,?.0¹?,²?]henicosa-1(13),4(9),5,7,14,18,20-heptaen-2-one

C25H24O7 (436.1521954)

Ala Cys Asp Glu

(2S)-2-[(2S)-2-[(2R)-2-[(2S)-2-aminopropanamido]-3-sulfanylpropanamido]-3-carboxypropanamido]pentanedioic acid

C15H24N4O9S (436.1263934)

Ala Cys Glu Asp

(2S)-2-[(2S)-2-[(2R)-2-[(2S)-2-aminopropanamido]-3-sulfanylpropanamido]-4-carboxybutanamido]butanedioic acid

C15H24N4O9S (436.1263934)

Ala Asp Cys Glu

(2S)-2-[(2R)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-carboxypropanamido]-3-sulfanylpropanamido]pentanedioic acid

C15H24N4O9S (436.1263934)

Ala Asp Glu Cys

(4S)-4-[(2S)-2-[(2S)-2-aminopropanamido]-3-carboxypropanamido]-4-{[(1R)-1-carboxy-2-sulfanylethyl]carbamoyl}butanoic acid

C15H24N4O9S (436.1263934)

Ala Asp Met Thr

(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-carboxypropanamido]-4-(methylsulfanyl)butanamido]-3-hydroxybutanoic acid