Exact Mass: 436.1521954
Exact Mass Matches: 436.1521954
Found 500 metabolites which its exact mass value is equals to given mass value 436.1521954,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Phlorizin
Phlorizin, also known as phlorizoside or phlorrhizen, belongs to the class of organic compounds known as flavonoid o-glycosides. Flavonoid O-glycosides are compounds containing a carbohydrate moiety which is O-glycosidically linked to the 2-phenylchromen-4-one flavonoid backbone. Phlorizin (also referred to as phloridzin; chemical name phloretin-2-‚âà√≠‚Äö√¢¬ß-D-glucopyranoside) is a glucoside of phloretin, a dihydrochalcone, a family of bicyclic flavonoids, which in turn is a subgroup in the diverse phenylpropanoid synthesis pathway in plants. In humans, phlorizin is involved in lactose degradation. Phlorizin is a bitter tasting compound. phlorizin is found, on average, in the highest concentration in a few different foods, such as mexican oregano, european plums, and apples and in a lower concentration in pomegranates and apricots. phlorizin has also been detected, but not quantified, in several different foods, such as epazotes, durians, chinese broccoli, sesames, and sweet potato. This could make phlorizin a potential biomarker for the consumption of these foods. It is of sweet taste and contains four molecules of water in the crystal. Phlorizin is found primarily in unripe Malus (apple), root bark of apple, trace amounts have been found in strawberry. It is poorly soluble in ether and cold water, but soluble in ethanol and hot water. Closely related species, such as pear (Pyrus communis), cherry, and other fruit trees in the Rosaceae do not contain phloridzin. Phlorizin was studied as a potential pharmaceutical treatment for type 2 diabetes, but has since been superseded by more selective and more promising synthetic analogs, such as empagliflozin, canagliflozin and dapagliflozin. Phlorizin is a competitive inhibitor of SGLT1 and SGLT2 because it competes with D-glucose for binding to the carrier; this reduces renal glucose transport, lowering the amount of glucose in the blood. Phlorizin is not an effective drug because when orally consumed, it is nearly entirely converted into phloretin by hydrolytic enzymes in the small intestine. Above 200 °C, it decomposes. Phlorizin is an aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 2 via a glycosidic linkage. It has a role as a plant metabolite and an antioxidant. It is an aryl beta-D-glucoside, a member of dihydrochalcones and a monosaccharide derivative. It is functionally related to a phloretin. Phlorizin is a natural product found in Malus doumeri, Vaccinium macrocarpon, and other organisms with data available. See also: ... View More ... An aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 2 via a glycosidic linkage. Isolated from apple leaves and bark Phlorizin (Floridzin) is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor. Phlorizin (Floridzin) is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor.
Sanggenon A
Sanggenon A is a member of chromenes. sanggenon A is a natural product found in Morus cathayana, Morus mongolica, and Morus alba with data available.
E-3174
EXP3174 is a metabolite of losartan (previous name DuP753), which is a non-peptide angiotensin II receptor antagonist. EXP3174, a metabolite of losartan (MK 954, DuP 753) is more potent than losartan in blocking the angiotensin II-induced responses in vascular smooth muscle cells. (PMID: 8385175) D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure[1][2][3][4].
Artonin J
Artonin J is found in fruits. Artonin J is a constituent of the root bark of Artocarpus heterophyllus (jackfruit). Constituent of the root bark of Artocarpus heterophyllus (jackfruit). Artonin J is found in jackfruit and fruits.
Trilobatin
C21H24O10 (436.13694039999996)
Trilobatin is found in pomes. Trilobatin is isolated from apple leaves. Isolated from apple leaves. Trilobatin is found in pomes. Trilobatin, a natural sweetener derived from?Lithocarpus polystachyus?Rehd[1], Trilobatin?is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope[2]. Neuroprotective effects[1]. Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells[3]. Trilobatin, a natural sweetener derived from?Lithocarpus polystachyus?Rehd[1], Trilobatin?is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope[2]. Neuroprotective effects[1]. Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells[3].
Artonin E
Artonin E is found in breadfruit. Artonin E is a constituent of Artocarpus communis (breadfruit). Constituent of Artocarpus communis (breadfruit). Artonin E is found in breadfruit and fruits.
Albanin B
Albanin B is found in fruits. Albanin B is isolated from Morus alba (white mulberry) infected with Fusarium solani. Isolated from Morus alba (white mulberry) infected with Fusarium solani. Albanin B is found in fruits.
Phenethyl 6-galloylglucoside
C21H24O10 (436.13694039999996)
Phenethyl 6-galloylglucoside is found in green vegetables. Phenethyl 6-galloylglucoside is isolated from Rosa damascena (damask rose Isolated from Rosa damascena (damask rose). Phenethyl 6-galloylglucoside is found in herbs and spices and green vegetables.
Delprostenato
C23H29ClO6 (436.16525640000003)
METESIND
C23H24N4O3S (436.15690340000003)
C471 - Enzyme Inhibitor > C2021 - Thymidylate Synthase Inhibitor
Nothofagin
C21H24O10 (436.13694039999996)
Phlorizine
C21H24O10 (436.13694039999996)
Phlorizin (Floridzin) is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor. Phlorizin (Floridzin) is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor.
1-Propanone, 1-(3-beta-D-glucopyranosyl-2,4-dihydroxyphenyl)-3-hydroxy-3-(4-hydroxyphenyl)-
C21H24O10 (436.13694039999996)
Trilobatin
C21H24O10 (436.13694039999996)
Trilobatin is an aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 4 via a glycosidic linkage. It is isolated from the leaves of the Chinese sweet tea Lithocarpus polystachyus and exhibits significant anti-hyperglycemic, anti-oxidative and anti-inflammatory properties. It has a role as an anti-inflammatory agent, a sweetening agent, an antioxidant and a plant metabolite. It is an aryl beta-D-glucoside, a member of dihydrochalcones and a monosaccharide derivative. It is functionally related to a phloretin. Trilobatin is a natural product found in Malus trilobata, Balanophora tobiracola, and other organisms with data available. An aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 4 via a glycosidic linkage. It is isolated from the leaves of the Chinese sweet tea Lithocarpus polystachyus and exhibits significant anti-hyperglycemic, anti-oxidative and anti-inflammatory properties. Trilobatin, a natural sweetener derived from?Lithocarpus polystachyus?Rehd[1], Trilobatin?is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope[2]. Neuroprotective effects[1]. Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells[3]. Trilobatin, a natural sweetener derived from?Lithocarpus polystachyus?Rehd[1], Trilobatin?is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope[2]. Neuroprotective effects[1]. Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells[3].
Coatline A
C21H24O10 (436.13694039999996)
2-Carboxy-3,4-dihydroxybibenzyl 3-O-6-D-glucopyranoside
C21H24O10 (436.13694039999996)
Broussonol B
Epiafzelechin 5-O-beta-D-glucopyranoside
C21H24O10 (436.13694039999996)
Ent-afzelechin-7-O-beta-D-glucopyranoside
C21H24O10 (436.13694039999996)
Kraussianone 7
Catechin 3-rhamnoside
C21H24O10 (436.13694039999996)
3,8-Bis(3-methoxy-4-hydroxyphenyl)-3,3a,8,8a-tetrahydro-1H-indeno[1,2-c]furan-5,7-diol
Sanggenon M
Nothofagin
C21H24O10 (436.13694039999996)
Nothofagin is a natural product found in Aspalathus linearis with data available.
Epiafzelechin 3-O-beta-D-allopyranoside
C21H24O10 (436.13694039999996)
Erysenegalensein L
Afzelechin 4-O-beta-D-glucopyranosdie
C21H24O10 (436.13694039999996)
Petalopurpurenol
Licoagroside F
C21H24O10 (436.13694039999996)
[3aS-[3aR*,4R*(Z),5R*,6R*,9S*,10E,11aS*]]-5-(Acetyloxy)-2,3,3a,4,5,6,7,8,9,11a-decahydro-6,9-dihydroxy-6,10-dimethyl-3-methylene-2,7-dioxocyclodeca[b]furan-4-yl ester 2-methylbutenoic acid
2-(1-Hydroxy-1-methylethyl)-3-hydroxy-2,3-dihydrofuranoalpinumisoflavone
Catechin 7-O-alpha-L-rhamnopyranoside
C21H24O10 (436.13694039999996)
Broussonol A
Epiafzelechin 3-O-beta-D-glucopyranoside
C21H24O10 (436.13694039999996)
Artonin E
Artonin J
Pterosupin
C21H24O10 (436.13694039999996)
Dihydrostilbene base + 3O, 1carboxy, O-Hex
C21H24O10 (436.13694039999996)
Annotation level-3
1-(2,4-dihydroxyphenyl)-3-hydroxy-3-(4-hydroxyphenyl-4-O-beta-D-glucopyranoside)-1-propanone
C21H24O10 (436.13694039999996)
samaderine X
A quassinoid isolated from Quassia indica and has been shown to exhibit antimalarial and cytotoxic activity.
luteoliflavan 5-beta-D-glucopyranoside
C21H24O10 (436.13694039999996)
3-O-beta-D-glucopyranosyl-1,3,4-trihydroxy-5-methoxy-alpha-phenylstyrene
C21H24O10 (436.13694039999996)
1-(2,4-dihydroxyphenyl-4-O-beta-D-glucopyranoside)-3-hydroxy-3-(4-hydroxyphenyl)-1-propanone
C21H24O10 (436.13694039999996)
4-O-beta-D-glucopyranosylbenzyl vanilloate|amburoside B
C21H24O10 (436.13694039999996)
7a,10a-dihydro-5-hydroxy-8,8-dimethyl-6-(2-methyl-1-oxobutyl)-4-phenyl-2H,8H-benzo[1,2]dioxolano[4,5:4,5]furo[2,3:5,6]benzo[1,2-b]pyran-2-one|mammea A/AB dioxalanocyclo E|Mammea A/AB dioxalanocyclo F
(-)-Epiafzelechin 7-O-beta-D-glucopyranoside
C21H24O10 (436.13694039999996)
9beta-acetoxy-8beta-(2-methyl-2,3-epoxybutyryloxy)-5-hydroxytrichosalviolide|9beta-acetoxy-8beta-<2-methyl-2,3-epoxybutyryloxy>-5-hydroxytrichosalviolide
8beta-Angeloyloxy-8-desacyloxytrichogoniolid-9-acetat
1-keto-3,10-epoxy-8beta-O-methacryloyl-4,15-dihydroxy-5-acetoxy-2,11-germacradiene, 6alpha,12-olide
C21H24O10 (436.13694039999996)
8alpha-O-(4-acetoxy-2-hydroxymethylbuten-2-oyloxy)salonitenolide
Catechin 3-O-alpha-L-rhamnopyranoside
C21H24O10 (436.13694039999996)
3-(3,4-Dihydroxyphenyl)-5-hydroxy-6-(2-hydroxy-3-methyl-3-butenyl)-8,8-dimethyl-4H,8H-benzo[1,2-b:3,4-b]dipyran-4-one
8alpha-(3-hydroxy-4-acetoxy-2-methylene-butanoyloxy)-4-epi-sonchucarpolide|8??-(3-Hydroxy-4-acetoxy-2-methylene-butanoyloxy)4-epi-sonchucarpolide
8alpha-O-(4-acetoxy-2-hydroxymethylbuten-2-oyloxy)-4-epi-sonchucarpolide
3,4-dihydro-10-hydroxy-7-methoxy-3-(R)-methyl-1H-3,4-dihydronaphtho-<2,3c>-pyran-1-one-9-O-beta-D-glucopyranoside|3,4-dihydro-10-hydroxy-7-methoxy-3-(R)-methyl-1H-3,4-dihydronaphtho-[2,3c]-pyran-1-one-9-O-beta-D-glucopyranoside
C21H24O10 (436.13694039999996)
2,4 dihydroxyphenyl-[6-O-(3-hydroxy,3-phenyl propanoyl)]-O-beta-D-allopyranoside
C21H24O10 (436.13694039999996)
3,4,4,5,5-Pentamethoxy-(2,3-oxydibenzoic acid dimethyl) ester
C21H24O10 (436.13694039999996)
(2R*,6aS,11bR)-6a,11b-dihydro-5,6a,9-trihydroxy-2-(1-methylethenyl)-11b-(3-methyl-2-buten-1-yl)-1H,2H,6H-benzofuro[3,2-b]pyrano[2,3-g][1]-benzofuro-6-one|(2S*,6aS,11bR)-6a,11b-dihydro-5,6a,9-trihydroxy-2-(1-methylethenyl)-11b-(3-methyl-2-buten-1-yl)-1H,2H,6H-benzofuro[3,2-b]pyrano[2,3-g][1]-benzofuro-6-one|nigrasin E|nigrasin F
(7E)-3,5,3,5-tetramethoxy-8:4-oxyneolign-7-ene-3,7,9,9-tetraol
7-acetoxy-8-[3-acetoxy-2,2-dimethyltetrahydro-4-furanyl]flavone|terpurinflavone
(2R,3S)-2-(4-hydroxy-3,5-dimethoxyphenyl)-2,3,5,6-tetrahydrophenanthro[2,1-b]pyran-3,8,11-triol|chrysotoxol B
(6R,7R,8S,3R)-8-(3,4-dihydroxy-2-methylenebutanoyloxy)-15-acetoxyhelianga-1(10),4(5),11(13)-trien-6,12-olide
2-[3-(3,4-dihydroxyphenyl)propanoyl]-3,5-dihydroxyphenyl alpha-L-rhamnopyranoside|3-hydroxyphloretin 2-alpha-O-L-rhamnopyranoside|glycyphyllin B
C21H24O10 (436.13694039999996)
4-(2-Hydroxy-3-methoxy-3-methylbutoxy)-9-(2,3-dihydroxy-3-methylbutoxy)-7H-furo[3,2-g][1]benzopyran-7-one
14-hydroxy-8-desacyl-2,3-dehydrovernonataloide-8-O-(2-methyl butyrate)|14-hydroxy-8-desacyl-2,3-dehydrovernonataloide-8-O-<2-methyl butyrate>
2-(5,8-dihydroxy-2,2-dimethyl-chroman-6-yl)-5-hydroxy-8,8-dimethyl-8H-pyrano[3,2-g]chromen-4-one|Chromanoartobilochromene b
2,6-dimethoxy-4-hydroxyphenyl 3-hydroxyphenyl ketone 3-O-beta-glucopyranoside|triptephenoside
C21H24O10 (436.13694039999996)
rel-6R-(2-hydroxy-2-methylbutanoyloxy)-8S-acetoxy-15-oxo-1S,2-epoxy-3,11(13)-elemandien-12,9-olide|zinagrandinolide A
Phlorizin
C21H24O10 (436.13694039999996)
Origin: Plant; Formula(Parent): C21H24O10; Bottle Name:Phloridzin; PRIME Parent Name:Phloretin-2-O-glucoside; PRIME in-house No.:S0307, Glycosides relative retention time with respect to 9-anthracene Carboxylic Acid is 0.718 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.713 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.714 Acquisition and generation of the data is financially supported by the Max-Planck-Society IPB_RECORD: 2021; CONFIDENCE confident structure Phlorizin (Floridzin) is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor. Phlorizin (Floridzin) is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor.
1-[2,4-dihydroxy-3-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]-2-hydroxy-3-(4-hydroxyphenyl)propan-1-one
C21H24O10 (436.13694039999996)
C21H24O10_(2S,3R)-3,5-Dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-yl beta-D-threo-hexopyranoside
C21H24O10 (436.13694039999996)
EXP 3174
A biphenylyltetrazole that is losartan with the hydroxymethyl group at position 5 on the imidazole ring replaced with a carboxylic acid. D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure[1][2][3][4].
1-[2,4-dihydroxy-3-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]-2-hydroxy-3-(4-hydroxyphenyl)propan-1-one
C21H24O10 (436.13694039999996)
3,7,21-trihydroxy-17,17-dimethyl-14-(3-methylbut-2-en-1-yl)-10,12,16-trioxapentacyclo[11.8.0.0³,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(13),4(9),5,7,14,18,20-heptaen-2-one
1-[2,4-dihydroxy-3-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]-2-hydroxy-3-(4-hydroxyphenyl)propan-1-one [IIN-based: Match]
C21H24O10 (436.13694039999996)
3,7,21-trihydroxy-17,17-dimethyl-14-(3-methylbut-2-en-1-yl)-10,12,16-trioxapentacyclo[11.8.0.0³,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(13),4(9),5,7,14,18,20-heptaen-2-one_35.3\\%
1-[2,4-dihydroxy-3-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]-2-hydroxy-3-(4-hydroxyphenyl)propan-1-one_major
C21H24O10 (436.13694039999996)
3,7,21-trihydroxy-17,17-dimethyl-14-(3-methylbut-2-en-1-yl)-10,12,16-trioxapentacyclo[11.8.0.0³,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(13),4(9),5,7,14,18,20-heptaen-2-one_major
3,7,21-trihydroxy-17,17-dimethyl-14-(3-methylbut-2-en-1-yl)-10,12,16-trioxapentacyclo[11.8.0.0³,¹¹.0?,?.0¹?,²?]henicosa-1(13),4(9),5,7,14,18,20-heptaen-2-one
Ala Asp Met Thr
Ala Asp Thr Met
Ala Glu Met Ser
Ala Glu Ser Met
Ala Met Asp Thr
Ala Met Glu Ser
Ala Met Ser Glu
Ala Met Thr Asp
Ala Ser Glu Met
Ala Ser Met Glu
Ala Thr Asp Met
Ala Thr Met Asp
Cys Asp Ile Ser
Cys Asp Leu Ser
Cys Asp Ser Ile
Cys Asp Ser Leu
Cys Asp Thr Val
Cys Asp Val Thr
Cys Glu Ser Val
Cys Glu Val Ser
Cys Ile Asp Ser
Cys Ile Ser Asp
Cys Leu Asp Ser
Cys Leu Ser Asp
Cys Met Pro Ser
Cys Met Ser Pro
Cys Asn Asn Ser
Cys Asn Ser Asn
Cys Pro Met Ser
Cys Pro Ser Met
Cys Ser Asp Ile
Cys Ser Asp Leu
Cys Ser Glu Val
Cys Ser Ile Asp
Cys Ser Leu Asp
Cys Ser Met Pro
Cys Ser Asn Asn
Cys Ser Pro Met
Cys Ser Val Glu
Cys Thr Asp Val
Cys Thr Val Asp
Cys Val Asp Thr
Cys Val Glu Ser
Cys Val Ser Glu
Cys Val Thr Asp
Asp Ala Met Thr
Asp Ala Thr Met
Asp Cys Ile Ser
Asp Cys Leu Ser
Asp Cys Ser Ile
Asp Cys Ser Leu
Asp Cys Thr Val
Asp Cys Val Thr
Asp Asp Ser Thr
C15H24N4O11 (436.14415139999994)
Asp Asp Thr Ser
C15H24N4O11 (436.14415139999994)
Asp Glu Ser Ser
C15H24N4O11 (436.14415139999994)
Asp Ile Cys Ser
Asp Ile Ser Cys
Asp Leu Cys Ser
Asp Leu Ser Cys
Asp Met Ala Thr
Asp Met Thr Ala
Asp Ser Cys Ile
Asp Ser Cys Leu
Asp Ser Asp Thr
C15H24N4O11 (436.14415139999994)
Asp Ser Glu Ser
C15H24N4O11 (436.14415139999994)
Asp Ser Ile Cys
Asp Ser Leu Cys
Asp Ser Ser Glu
C15H24N4O11 (436.14415139999994)
Asp Ser Thr Asp
C15H24N4O11 (436.14415139999994)
Asp Thr Ala Met
Asp Thr Cys Val
Asp Thr Asp Ser
C15H24N4O11 (436.14415139999994)
Asp Thr Met Ala
Asp Thr Ser Asp
C15H24N4O11 (436.14415139999994)
Asp Thr Val Cys
Asp Val Cys Thr
Asp Val Thr Cys
Glu Ala Met Ser
Glu Ala Ser Met
Glu Cys Ser Val
Glu Cys Val Ser
Glu Asp Ser Ser
C15H24N4O11 (436.14415139999994)
Glu Gly Met Thr
Glu Gly Thr Met
Glu Met Ala Ser
Glu Met Gly Thr
Glu Met Ser Ala
Glu Met Thr Gly
Glu Ser Ala Met
Glu Ser Cys Val
Glu Ser Asp Ser
C15H24N4O11 (436.14415139999994)
Glu Ser Met Ala
Glu Ser Ser Asp
C15H24N4O11 (436.14415139999994)
Glu Ser Val Cys
Glu Thr Gly Met
Glu Thr Met Gly
Glu Val Cys Ser
Glu Val Ser Cys
Gly Glu Met Thr
Gly Glu Thr Met
Gly Met Glu Thr
Gly Met Thr Glu
Gly Thr Glu Met
Gly Thr Met Glu
Ile Cys Asp Ser
Ile Cys Ser Asp
Ile Asp Cys Ser
Ile Asp Ser Cys
Ile Ser Cys Asp
Ile Ser Asp Cys
Leu Cys Asp Ser
Leu Cys Ser Asp
Leu Asp Cys Ser
Leu Asp Ser Cys
Leu Ser Cys Asp
Leu Ser Asp Cys
Met Ala Asp Thr
Met Ala Glu Ser
Met Ala Ser Glu
Met Ala Thr Asp
Met Cys Pro Ser
Met Cys Ser Pro
Met Asp Ala Thr
Met Asp Thr Ala
Met Glu Ala Ser
Met Glu Gly Thr
Met Glu Ser Ala
Met Glu Thr Gly
Met Gly Glu Thr
Met Gly Thr Glu
Met Pro Cys Ser
Met Pro Ser Cys
Met Ser Ala Glu
Met Ser Cys Pro
Met Ser Glu Ala
Met Ser Pro Cys
Met Thr Ala Asp
Met Thr Asp Ala
Met Thr Glu Gly
Met Thr Gly Glu
Asn Cys Asn Ser
Asn Cys Ser Asn
Asn Asn Cys Ser
Asn Asn Ser Cys
Asn Ser Cys Asn
Asn Ser Asn Cys
Pro Cys Met Ser
Pro Cys Ser Met
Pro Met Cys Ser
Pro Met Ser Cys
Pro Ser Cys Met
Pro Ser Met Cys
Ser Ala Glu Met
Ser Ala Met Glu
Ser Cys Asp Ile
Ser Cys Asp Leu
Ser Cys Glu Val
Ser Cys Ile Asp
Ser Cys Leu Asp
Ser Cys Met Pro
Ser Cys Asn Asn
Ser Cys Pro Met
Ser Cys Val Glu
Ser Asp Cys Ile
Ser Asp Cys Leu
Ser Asp Asp Thr
C15H24N4O11 (436.14415139999994)
Ser Asp Glu Ser
C15H24N4O11 (436.14415139999994)
Ser Asp Ile Cys
Ser Asp Leu Cys
Ser Asp Ser Glu
C15H24N4O11 (436.14415139999994)
Ser Asp Thr Asp
C15H24N4O11 (436.14415139999994)
Ser Glu Ala Met
Ser Glu Cys Val
Ser Glu Asp Ser
C15H24N4O11 (436.14415139999994)
Ser Glu Met Ala
Ser Glu Ser Asp
C15H24N4O11 (436.14415139999994)
Ser Glu Val Cys
Ser Ile Cys Asp
Ser Ile Asp Cys
Ser Leu Cys Asp
Ser Leu Asp Cys
Ser Met Ala Glu
Ser Met Cys Pro
Ser Met Glu Ala
Ser Met Pro Cys
Ser Asn Cys Asn
Ser Asn Asn Cys
Ser Pro Cys Met
Ser Pro Met Cys
Ser Ser Asp Glu
C15H24N4O11 (436.14415139999994)
Ser Ser Glu Asp
C15H24N4O11 (436.14415139999994)
Ser Thr Asp Asp
C15H24N4O11 (436.14415139999994)
Ser Val Cys Glu
Ser Val Glu Cys
Thr Ala Asp Met
Thr Ala Met Asp
Thr Cys Asp Val
Thr Cys Val Asp
Thr Asp Ala Met
Thr Asp Cys Val
Thr Asp Asp Ser
C15H24N4O11 (436.14415139999994)
Thr Asp Met Ala
Thr Asp Ser Asp
C15H24N4O11 (436.14415139999994)
Thr Asp Val Cys
Thr Glu Gly Met
Thr Glu Met Gly
Thr Gly Glu Met
Thr Gly Met Glu
Thr Met Ala Asp
Thr Met Asp Ala
Thr Met Glu Gly
Thr Met Gly Glu
Thr Ser Asp Asp
C15H24N4O11 (436.14415139999994)
Thr Val Cys Asp
Thr Val Asp Cys
Val Cys Asp Thr
Val Cys Glu Ser
Val Cys Ser Glu
Val Cys Thr Asp
Val Asp Cys Thr
Val Asp Thr Cys
Val Glu Cys Ser
Val Glu Ser Cys
Val Ser Cys Glu
Val Ser Glu Cys
Val Thr Cys Asp
Val Thr Asp Cys
Albanin B
Phenethyl 6-galloylglucoside
C21H24O10 (436.13694039999996)
Afzelechin 4-O-beta-D-glucopyranoside
C21H24O10 (436.13694039999996)
1-methyl-5-[5-(4-methylpiperazin-1-yl)sulfonylthiophen-3-yl]-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one
C18H24N6O3S2 (436.13512339999994)
(2R,4S)-1-(((9H-FLUOREN-9-YL)METHOXY)CARBONYL)-4-(((ALLYLOXY)CARBONYL)AMINO)PYRROLIDINE-2-CARBOXYLIC ACID
2H-Tetrazolium,2,5-diphenyl-3-[4-(2-phenylethenyl)phenyl]-, chloride (1:1)
4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
2-(((3AR,4R,6R,6AR)-6-(6-AMINO-9H-PURIN-9-YL)-2,2-DIMETHYLTETRAHYDROFURO[3,4-D][1,3]DIOXOL-4-YL)METHYL)ISOINDOLINE-1,3-DIONE
[4-(2,4-difluorophenyl)-2-(4-methylpiperazine-1-carbonyl)phenyl] benzoate
C25H22F2N2O3 (436.15984060000005)
benzene-1,3-dicarboxylic acid,2,2-dimethylpropane-1,3-diol,terephthalic acid
C21H24O10 (436.13694039999996)
1-[2-[[4-[(2-cyano-4-nitrophenyl)azo]phenyl]ethylamino]ethyl]pyridinium chloride
3a,4,5,6,7,7a-hexahydro-2-benzofuran-1,3-dione,2-benzofuran-1,3-dione,2-ethyl-2-(hydroxymethyl)propane-1,3-diol
Benzyl 3,4,6-tri-O-acetyl-N-acetyl-alpha-D-galactosaminide
C21H26NO9- (436.16074860000003)
Methanol, 1-(2-Methoxyethoxy)-, 1-benzoateMethanol, (2-Methoxyethoxy)-, benzoate (9CI)
4-[(ALLYLOXY)CARBONYL]PIPERAZINE-2-CARBOXYLIC ACID, N1-FMOC PROTECTED 974-ALLYL 1-(9-H-FLUOREN-9-YLMETHYL) HYDROGEN PIPERAZINE-1,2,4-TRICARBOXYLATE
4-[4-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1-piperidinyl]-3-nitrobenzoic acid methyl ester
Bis-1,2-{[(Z)-2-carboxy-2-methyl-1,3-dioxane]-5-yloxycarbamoyl}-ethane
(2S,3R,4S,5S,6R)-2-[[(2S,3R)-3,5-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
C21H24O10 (436.13694039999996)
7-[(3S)-(3-amino-3-carboxypropyl)-4-methyl]wyosine
C18H24N6O7 (436.17063939999997)
2-amino-4-[3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4,6-dimethyl-9-oxoimidazo[1,2-a]purin-7-yl]butanoic acid
C18H24N6O7 (436.17063939999997)
methyl (2E,5E)-7-[2-[(E)-4-(3-chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl]hepta-2,5-dienoate
C23H29ClO6 (436.16525640000003)
nigrasin E
An extended flavonoid that is 1,2,6a,11b-tetrahydro-6H-[1]benzofuro[3,2-b]furo[2,3-h]chromene substituted by hydroxy groups at positions 5, 6a and 9, a prenyl group at position 11b, a prop-1-en-2-yl group at position 2 and an oxo group at position 6. It has been isolated from the twigs of Morus nigra.
nigrasin F
An extended flavonoid that is the 2S*-diastereomer of nigrasin E. It has been isolated from the twigs of Morus nigra.
6-(3-cyclopentyloxy-4-methoxyphenyl)-3-(2-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
C23H24N4O3S (436.15690340000003)
3-Benzoylamino-1-[2-(4-benzoylamino-phenyl)-2-oxo-ethyl]-pyridinium
C27H22N3O3+ (436.16610820000005)
N-[5-chloro-2-(4-methyl-1-piperazinyl)phenyl]-3-(dimethylsulfamoyl)benzamide
C20H25ClN4O3S (436.13358100000005)
1-(4-Ethoxyphenyl)-5-[[4-(4-morpholinyl)anilino]methylidene]-1,3-diazinane-2,4,6-trione
(5-Furan-2-yl-2,2-dimethyl-1,4-dihydro-2H-3-oxa-7-thia-6,9,11-triaza-benzo[c]fluoren-8-yl)-(tetrahydro-furan-2-ylmethyl)-amine
C23H24N4O3S (436.15690340000003)
1-(3,5-Dimethylphenyl)-5-[[4-(4-morpholinyl)anilino]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione
C23H24N4O3S (436.15690340000003)
N-(4-chlorophenyl)-4-[hydroxy(diphenyl)methyl]-1-piperidinecarbothioamide
1-[2-(5-fluoro-2-methyl-1H-indol-3-yl)ethyl]-3-(4-fluorophenyl)-1-(pyridin-4-ylmethyl)thiourea
C24H22F2N4S (436.15331560000004)
1-[1-(4-Methoxyphenyl)-2,5-dimethyl-3-pyrrolyl]-2-[[4-methyl-5-(2-methyl-3-furanyl)-1,2,4-triazol-3-yl]thio]ethanone
C23H24N4O3S (436.15690340000003)
3-[4-[2-(3,4-Dimethoxyphenyl)-2-oxoethyl]-3-oxo-[1,2,4]triazino[2,3-a]benzimidazol-2-yl]propanoic acid
N-[(3-methoxyphenyl)methyl]-1-[(6-methyl-2,4-dioxo-1H-pyrimidin-5-yl)sulfonyl]-3-piperidinecarboxamide
N-[5-(diethylsulfamoyl)-2-methoxyphenyl]-2-[(2,5-dimethylphenyl)thio]acetamide
6-Amino-5,7,7-tricyano-8-pyridin-4-yl-1,3,8,8a-tetrahydroisoquinoline-2-carboxylic acid (phenylmethyl) ester
4-[[2-(1,10b-Dihydropyrazolo[1,5-c]quinazolin-5-ylthio)-1-oxoethyl]amino]benzoic acid butyl ester
C23H24N4O3S (436.15690340000003)
N-(3-chloro-4-fluorophenyl)-N-[2-(2-methoxyethylamino)-2-oxoethyl]-N-(2-pyridinyl)butanediamide
1-[2-(5-fluoro-2-methyl-1H-indol-3-yl)ethyl]-3-(3-fluorophenyl)-1-(3-pyridinylmethyl)thiourea
C24H22F2N4S (436.15331560000004)
1-[2-(5-fluoro-2-methyl-1H-indol-3-yl)ethyl]-3-(4-fluorophenyl)-1-(3-pyridinylmethyl)thiourea
C24H22F2N4S (436.15331560000004)
9-(3-(3,5-Dinitrobenzoylamino)-3-methylpropyl)-1,2,3,4-tetrahydrocarbazole
(1R,2aS,8bS)-N-(2,5-difluorophenyl)-1-(hydroxymethyl)-2-(3-pyridinylmethyl)-1,2a,3,8b-tetrahydroazeto[2,3-c]quinoline-4-carboxamide
(1S,2aR,8bR)-N-(2,5-difluorophenyl)-1-(hydroxymethyl)-2-(3-pyridinylmethyl)-1,2a,3,8b-tetrahydroazeto[2,3-c]quinoline-4-carboxamide
(1S)-N-(1,3-benzodioxol-5-yl)-1-(hydroxymethyl)-7-methoxy-1-spiro[1,2,3,9-tetrahydropyrido[3,4-b]indole-4,3-azetidine]carboxamide
(1S,2aS,8bS)-N-(2,5-difluorophenyl)-1-(hydroxymethyl)-2-(3-pyridinylmethyl)-1,2a,3,8b-tetrahydroazeto[2,3-c]quinoline-4-carboxamide
(1R,2aR,8bR)-N-(2,5-difluorophenyl)-1-(hydroxymethyl)-2-(3-pyridinylmethyl)-1,2a,3,8b-tetrahydroazeto[2,3-c]quinoline-4-carboxamide
(1R)-N-(1,3-benzodioxol-5-yl)-1-(hydroxymethyl)-7-methoxy-1-spiro[1,2,3,9-tetrahydropyrido[3,4-b]indole-4,3-azetidine]carboxamide
6-[3-[2-(2,5-Dihydroxyphenyl)ethyl]-5-methoxyphenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
C21H24O10 (436.13694039999996)
7-[(3S)-3-azaniumyl-3-carboxylatopropyl]-4,6-dimethyl-3-(5-O-phosphono-beta-D-ribofuranosyl)-3,4-dihydro-9H-imidazo[1,2-a]purin-9-one
C18H24N6O7 (436.17063939999997)
2-(3-hydroxyphenyl)-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,4-dihydro-2H-chromene-3,5,7-triol
C21H24O10 (436.13694039999996)
(E)-N-(4-ethoxyphenyl)-3-hydroxy-3-(4-methyl-3-nitrophenyl)-2-pyridin-1-ium-1-ylprop-2-enethioamide
C23H22N3O4S+ (436.13309520000007)
3,4,5-Trihydroxy-6-[8-methoxy-6-(3-methylbut-2-enyl)-2-oxochromen-7-yl]oxyoxane-2-carboxylic acid
C21H24O10 (436.13694039999996)
(2S)-2-amino-4-[3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4,6-dimethyl-9-oxoimidazo[1,2-a]purin-7-yl]butanoic acid
C18H24N6O7 (436.17063939999997)
Phlorizine
C21H24O10 (436.13694039999996)
7-(3-amino-3-carboxypropyl)wyosine 5-monophosphate zwitterion
C18H24N6O7 (436.17063939999997)
An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of 7-(3-amino-3-carboxypropyl)wyosine 5-monophosphate.
(-)-(7S,7S,8R,8R)-4,4-dihydroxy-3,3,5,5-tetramethoxy-7,7-epoxylignan-9,9-diol
A natural product found in Machilus robusta.
EVT-401
C22H20F4N2O3 (436.14099780000004)
EVT-401 (P2X7 receptor antagonist-1) is a purinergic P2X7 receptor antagonist. EVT-401 has efficacy of combating?neuroinflammation[1].
VU0155094
C24H24N2O4S (436.14567040000003)
VU0155094 is a positive allosteric modulator with differential activity at the various group III mGluRs[1].