Phlorizine (BioDeep_00000182361)

Main id: BioDeep_00000000068

 

human metabolite PANOMIX_OTCML-2023 blood metabolite natural product


Metabolite Card


1-(2,4-dihydroxy-6-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)-3-(4-hydroxyphenyl)propan-1-one

  Formula: C21H24O10 (436.1369)
Chinese Names: 根皮苷
  Spectrum Hits: Top Source () 0%

Molecular Structure

SMILES: c1(cc(c(c(c1)O)C(=O)CCc1ccc(cc1)O)O[C@@H]1O[C@H]([C@H]([C@@H]([C@@H]1O)O)O)CO)O
InChI: InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-15-8-12(24)7-14(26)17(15)13(25)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-24,26-29H,3,6,9H2


Description

Phlorizin (Floridzin) is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor.
Phlorizin (Floridzin) is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor.

Synonyms

7 synonym names

1-(2,4-dihydroxy-6-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)-3-(4-hydroxyphenyl)propan-1-one; Phloretin 2-glucoside; Phlorizine; Phloridzin; Phlorizin; Floridzin; Phlorizin



Cross Reference

10 cross reference id

Classification Terms

Related Pathways

Reactome(0)

BioCyc(0)

PlantCyc(0)

Biological Process

0 related biological process reactions.

Reactome(0)

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Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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PharmGKB(0)

83 organism taxonomy source information

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Sub-cellular location Genes


Literature Reference