Phlorizine (BioDeep_00001875509)

   


代谢物信息卡片


1-[2,4-Dihydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one

化学式: C21H24O10 (436.13694039999996)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2OC3C(C(C(C(O3)CO)O)O)O)O)O)O
InChI: InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-15-8-12(24)7-14(26)17(15)13(25)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-24,26-29H,3,6,9H2



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Svetlana S Efimova, Olga S Ostroumova. Effect of dipole modifiers on the magnitude of the dipole potential of sterol-containing bilayers. Langmuir : the ACS journal of surfaces and colloids. 2012 Jul; 28(26):9908-14. doi: 10.1021/la301653s. [PMID: 22702338]
  • Han-Xiang Wu, Wen Yang, Zhi-Xiang Zhang, Ting Huang, Guang-Kai Yao, Han-Hong Xu. Uptake and phloem transport of glucose-fipronil conjugate in Ricinus communis involve a carrier-mediated mechanism. Journal of agricultural and food chemistry. 2012 Jun; 60(24):6088-94. doi: 10.1021/jf300546t. [PMID: 22587652]
  • Oliver J Mace, Marcus Schindler, Sonal Patel. The regulation of K- and L-cell activity by GLUT2 and the calcium-sensing receptor CasR in rat small intestine. The Journal of physiology. 2012 Jun; 590(12):2917-36. doi: 10.1113/jphysiol.2011.223800. [PMID: 22495587]
  • Sabaz Ali Khan, Pierre-Yves Chibon, Ric C H de Vos, Bert A Schipper, Evert Walraven, Jules Beekwilder, Thijs van Dijk, Richard Finkers, Richard G F Visser, Eric W van de Weg, Arnaud Bovy, Alessandro Cestaro, Riccardo Velasco, Evert Jacobsen, Henk J Schouten. Genetic analysis of metabolites in apple fruits indicates an mQTL hotspot for phenolic compounds on linkage group 16. Journal of experimental botany. 2012 May; 63(8):2895-908. doi: 10.1093/jxb/err464. [PMID: 22330898]
  • Mahmood Najafian, Mohammad Zareain Jahromi, Mohammad Javad Nowroznejhad, Parastoo Khajeaian, Mohammad Mehdi Kargar, Mehdi Sadeghi, Amir Arasteh. Phloridzin reduces blood glucose levels and improves lipids metabolism in streptozotocin-induced diabetic rats. Molecular biology reports. 2012 May; 39(5):5299-306. doi: 10.1007/s11033-011-1328-7. [PMID: 22167331]
  • Chunnian He, Yong Peng, Wei Xiao, Yuli Hu, Peigen Xiao. [Quick determination of five sweet constituents in Duosuike Tiancha by RSLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2012 Apr; 37(7):961-5. doi: ". [PMID: 22792798]
  • Matthias Fromm, Sandra Bayha, Reinhold Carle, Dietmar R Kammerer. Characterization and quantitation of low and high molecular weight phenolic compounds in apple seeds. Journal of agricultural and food chemistry. 2012 Feb; 60(5):1232-42. doi: 10.1021/jf204623d. [PMID: 22220632]
  • David Chagné, Célia Krieger, Maysoon Rassam, Mike Sullivan, Jenny Fraser, Christelle André, Massimo Pindo, Michela Troggio, Susan E Gardiner, Rebecca A Henry, Andrew C Allan, Tony K McGhie, William A Laing. QTL and candidate gene mapping for polyphenolic composition in apple fruit. BMC plant biology. 2012 Jan; 12(?):12. doi: 10.1186/1471-2229-12-12. [PMID: 22269060]
  • Miyuki Shirosaki, Tomoyuki Koyama, Kazunaga Yazawa. Suppressive effect of peach leaf extract on glucose absorption from the small intestine of mice. Bioscience, biotechnology, and biochemistry. 2012; 76(1):89-94. doi: 10.1271/bbb.110541. [PMID: 22232239]
  • Tetsuya Iizuka, Toshiki Tamura, Hideki Sezutsu, Keisuke Mase, Eiji Okada, Kiyoshi Asaoka. Genetic analysis of the electrophysiological response to salicin, a bitter substance, in a polyphagous strain of the silkworm Bombyx mori. PloS one. 2012; 7(5):e37549. doi: 10.1371/journal.pone.0037549. [PMID: 22649537]
  • Supanimit Teekachunhatean, Sujitra Techatoei, Noppamas Rojanasthein, Maleeya Manorot, Chaichan Sangdee. Influence of fructooligosaccharide on pharmacokinetics of isoflavones in postmenopausal women. Evidence-based complementary and alternative medicine : eCAM. 2012; 2012(?):783802. doi: 10.1155/2012/783802. [PMID: 22611432]
  • William H Karasov, Enrique Caviedes-Vidal, Bradley Hartman Bakken, Ido Izhaki, Michal Samuni-Blank, Zeev Arad. Capacity for absorption of water-soluble secondary metabolites greater in birds than in rodents. PloS one. 2012; 7(2):e32417. doi: 10.1371/journal.pone.0032417. [PMID: 22389702]
  • Gaigai Deng, Junzhi Wang, Qiaoyin Zhang, Haibo He, Fangfang Wu, Tianyan Feng, Jigang Zhou, Kun Zou, Masao Hattori. Hepatoprotective effects of phloridzin on hepatic fibrosis induced by carbon tetrachloride against oxidative stress-triggered damage and fibrosis in rats. Biological & pharmaceutical bulletin. 2012; 35(7):1118-25. doi: 10.1248/bpb.b12-00057. [PMID: 22791160]
  • Miyuki Shirosaki, Tomoyuki Koyama, Kazunaga Yazawa. Apple leaf extract as a potential candidate for suppressing postprandial elevation of the blood glucose level. Journal of nutritional science and vitaminology. 2012; 58(1):63-7. doi: 10.3177/jnsv.58.63. [PMID: 23007070]
  • Zenghui Teng, Chengjun Yuan, Feng Zhang, Menglei Huan, Weidong Cao, Kangchu Li, Jingyue Yang, Dayong Cao, Siyuan Zhou, Qibing Mei. Intestinal absorption and first-pass metabolism of polyphenol compounds in rat and their transport dynamics in Caco-2 cells. PloS one. 2012; 7(1):e29647. doi: 10.1371/journal.pone.0029647. [PMID: 22253753]
  • Rui Zhang, Yang Yao, Yingping Wang, Guixing Ren. Antidiabetic activity of isoquercetin in diabetic KK -Ay mice. Nutrition & metabolism. 2011 Dec; 8(?):85. doi: 10.1186/1743-7075-8-85. [PMID: 22133267]
  • Aleksandra Duda-Chodak, Tomasz Tarko, Tadeusz Tuszyński. Antioxidant activity of apples--an impact of maturity stage and fruit part. Acta scientiarum polonorum. Technologia alimentaria. 2011 Oct; 10(4):443-54. doi: ". [PMID: 22230926]
  • Sónia A O Santos, Carmen S R Freire, M Rosário M Domingues, Armando J D Silvestre, Carlos Pascoal Neto. Characterization of phenolic components in polar extracts of Eucalyptus globulus Labill. bark by high-performance liquid chromatography-mass spectrometry. Journal of agricultural and food chemistry. 2011 Sep; 59(17):9386-93. doi: 10.1021/jf201801q. [PMID: 21761864]
  • Yuanyuan Yue, Jianming Liu, Jing Fan, Xiaojun Yao. Binding studies of phloridzin with human serum albumin and its effect on the conformation of protein. Journal of pharmaceutical and biomedical analysis. 2011 Sep; 56(2):336-42. doi: 10.1016/j.jpba.2011.05.018. [PMID: 21665402]
  • Bettina Gutbrodt, Karsten Mody, Raphaël Wittwer, Silvia Dorn. Within-plant distribution of induced resistance in apple seedlings: rapid acropetal and delayed basipetal responses. Planta. 2011 Jun; 233(6):1199-207. doi: 10.1007/s00425-011-1371-6. [PMID: 21327817]
  • Lishuang Lv, Xi Shao, Huadong Chen, Chi-Tang Ho, Shengmin Sang. Genistein inhibits advanced glycation end product formation by trapping methylglyoxal. Chemical research in toxicology. 2011 Apr; 24(4):579-86. doi: 10.1021/tx100457h. [PMID: 21344933]
  • Patrice E Fort, Mandy K Losiewicz, Chad E N Reiter, Ravi S J Singh, Makoto Nakamura, Steven F Abcouwer, Alistair J Barber, Thomas W Gardner. Differential roles of hyperglycemia and hypoinsulinemia in diabetes induced retinal cell death: evidence for retinal insulin resistance. PloS one. 2011; 6(10):e26498. doi: 10.1371/journal.pone.0026498. [PMID: 22046295]
  • An-Long Hu, Wen Yang, Han-Hong Xu. Novel fluorescent conjugate containing glucose and NBD and its carrier-mediated uptake by tobacco cells. Journal of photochemistry and photobiology. B, Biology. 2010 Dec; 101(3):215-23. doi: 10.1016/j.jphotobiol.2010.07.006. [PMID: 20692850]
  • Susana Manzano, Gary Williamson. Polyphenols and phenolic acids from strawberry and apple decrease glucose uptake and transport by human intestinal Caco-2 cells. Molecular nutrition & food research. 2010 Dec; 54(12):1773-80. doi: 10.1002/mnfr.201000019. [PMID: 20564476]
  • Hideaki Oike, Kanji Nagai, Tatsunobu Fukushima, Norio Ishida, Masuko Kobori. High-salt diet advances molecular circadian rhythms in mouse peripheral tissues. Biochemical and biophysical research communications. 2010 Nov; 402(1):7-13. doi: 10.1016/j.bbrc.2010.09.072. [PMID: 20888322]
  • J F Ayala-Zavala, C Rosas-Domínguez, V Vega-Vega, G A González-Aguilar. Antioxidant enrichment and antimicrobial protection of fresh-cut fruits using their own byproducts: looking for integral exploitation. Journal of food science. 2010 Oct; 75(8):R175-81. doi: 10.1111/j.1750-3841.2010.01792.x. [PMID: 21535513]
  • Sachin A Paranjape, Owen Chan, Wanling Zhu, Adam M Horblitt, Ewan C McNay, James A Cresswell, Jonathan S Bogan, Rory J McCrimmon, Robert S Sherwin. Influence of insulin in the ventromedial hypothalamus on pancreatic glucagon secretion in vivo. Diabetes. 2010 Jun; 59(6):1521-7. doi: 10.2337/db10-0014. [PMID: 20299468]
  • Christian Gosch, Heidi Halbwirth, Karl Stich. Phloridzin: biosynthesis, distribution and physiological relevance in plants. Phytochemistry. 2010 Jun; 71(8-9):838-43. doi: 10.1016/j.phytochem.2010.03.003. [PMID: 20356611]
  • Sonia A Tucci, Emma J Boyland, Jason Cg Halford. The role of lipid and carbohydrate digestive enzyme inhibitors in the management of obesity: a review of current and emerging therapeutic agents. Diabetes, metabolic syndrome and obesity : targets and therapy. 2010 May; 3(?):125-43. doi: 10.2147/dmsott.s7005. [PMID: 21437083]
  • Sheng-Hua Li, Xian-Jin Wu, Qing-Dan Yang, Yuan-Yang Chen, Nan Zhou. [Studies on the chemical constituents of Lithocarpus polystachyus]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2010 Apr; 33(4):549-51. doi: ". [PMID: 20845782]
  • Kati Hanhineva, Riitta Törrönen, Isabel Bondia-Pons, Jenna Pekkinen, Marjukka Kolehmainen, Hannu Mykkänen, Kaisa Poutanen. Impact of dietary polyphenols on carbohydrate metabolism. International journal of molecular sciences. 2010 Mar; 11(4):1365-402. doi: 10.3390/ijms11041365. [PMID: 20480025]
  • Dieter Treutter. Managing phenol contents in crop plants by phytochemical farming and breeding-visions and constraints. International journal of molecular sciences. 2010 Mar; 11(3):807-57. doi: 10.3390/ijms11030807. [PMID: 20479987]
  • Thomas Dugé de Bernonville, Sylvain Guyot, Jean-Pierre Paulin, Matthieu Gaucher, Laurent Loufrani, Daniel Henrion, Séverine Derbré, David Guilet, Pascal Richomme, James F Dat, Marie-Noëlle Brisset. Dihydrochalcones: Implication in resistance to oxidative stress and bioactivities against advanced glycation end-products and vasoconstriction. Phytochemistry. 2010 Mar; 71(4):443-52. doi: 10.1016/j.phytochem.2009.11.004. [PMID: 20022617]
  • Christian Rössle, Hilde H Wijngaard, Ronan T Gormley, Francis Butler, Nigel Brunton. Effect of storage on the content of polyphenols of minimally processed skin-on apple wedges from ten cultivars and two growing seasons. Journal of agricultural and food chemistry. 2010 Feb; 58(3):1609-14. doi: 10.1021/jf903621y. [PMID: 20000411]
  • H P Vasantha Rupasinghe, Afsana Yasmin. Inhibition of oxidation of aqueous emulsions of omega-3 fatty acids and fish oil by phloretin and phloridzin. Molecules (Basel, Switzerland). 2010 Jan; 15(1):251-7. doi: 10.3390/molecules15010251. [PMID: 20110888]
  • Meng-Fu Cheng, Li-Jen Chen, Juei-Tang Cheng. Decrease of Klotho in the kidney of streptozotocin-induced diabetic rats. Journal of biomedicine & biotechnology. 2010; 2010(?):513853. doi: 10.1155/2010/513853. [PMID: 20625492]
  • Junzhi Wang, Mi Hwa Chung, Bingjie Xue, Hong Ma, Chaomei Ma, Masao Hattori. Estrogenic and antiestrogenic activities of phloridzin. Biological & pharmaceutical bulletin. 2010; 33(4):592-7. doi: 10.1248/bpb.33.592. [PMID: 20410591]
  • Ryszard Amarowicz, Isabell Estrella, Teresa Hernández, Montserrat Dueñas, Agnieszka Troszyńska, Agnieszka Kosińska, Ronald B Pegg. Antioxidant activity of a red lentil extract and its fractions. International journal of molecular sciences. 2009 Dec; 10(12):5513-5527. doi: 10.3390/ijms10125513. [PMID: 20054484]
  • Ryuichi Moriya, Takashi Shirakura, Junko Ito, Satoshi Mashiko, Toru Seo. Activation of sodium-glucose cotransporter 1 ameliorates hyperglycemia by mediating incretin secretion in mice. American journal of physiology. Endocrinology and metabolism. 2009 Dec; 297(6):E1358-65. doi: 10.1152/ajpendo.00412.2009. [PMID: 19808907]
  • Mahbubeh Setorki, Sedighe Asgary, Akram Eidi, Ali Haeri Rohani, Nafiseh Esmaeil. Effects of apple juice on risk factors of lipid profile, inflammation and coagulation, endothelial markers and atherosclerotic lesions in high cholesterolemic rabbits. Lipids in health and disease. 2009 Oct; 8(?):39. doi: 10.1186/1476-511x-8-39. [PMID: 19804641]
  • Jordi Altirriba, Albert Barbera, Héctor Del Zotto, Belen Nadal, Sandra Piquer, Alex Sánchez-Pla, Juan J Gagliardino, Ramon Gomis. Molecular mechanisms of tungstate-induced pancreatic plasticity: a transcriptomics approach. BMC genomics. 2009 Aug; 10(?):406. doi: 10.1186/1471-2164-10-406. [PMID: 19715561]
  • C H Yeh, C K Chang, M F Cheng, H J Lin, J T Cheng. Decrease of bone morphogenetic protein-7 (BMP-7) and its type II receptor (BMP-RII) in kidney of type 1-like diabetic rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 2009 Aug; 41(8):605-11. doi: 10.1055/s-0029-1220736. [PMID: 19440953]
  • Elena Di Daniel, Man H S Mok, Emma Mead, Chiara Mutinelli, Erika Zambello, Laura L Caberlotto, Theresa J Pell, Christopher J Langmead, Ajit J Shah, Graham Duddy, James N C Kew, Peter R Maycox. Evaluation of expression and function of the H+/myo-inositol transporter HMIT. BMC cell biology. 2009 Jul; 10(?):54. doi: 10.1186/1471-2121-10-54. [PMID: 19607714]
  • Saeko Masumoto, Yukari Akimoto, Hideaki Oike, Masuko Kobori. Dietary phloridzin reduces blood glucose levels and reverses Sglt1 expression in the small intestine in streptozotocin-induced diabetic mice. Journal of agricultural and food chemistry. 2009 Jun; 57(11):4651-6. doi: 10.1021/jf9008197. [PMID: 19413312]
  • Denis R Lauren, Wendy A Smith, Aselle Adaim, Janine M Cooney, Reginald Wibisono, Dwayne J Jensen, Jingli Zhang, Margot A Skinner. Chemical composition and in vitro anti-inflammatory activity of apple phenolic extracts and of their sub-fractions. International journal of food sciences and nutrition. 2009; 60 Suppl 7(?):188-205. doi: 10.1080/09637480902849203. [PMID: 19391030]
  • Gopaljee Jha, Karnika Thakur, Priyanka Thakur. The Venturia apple pathosystem: pathogenicity mechanisms and plant defense responses. Journal of biomedicine & biotechnology. 2009; 2009(?):680160. doi: 10.1155/2009/680160. [PMID: 20150969]
  • Alexandra Paulo, Sofia Martins, Pedro Branco, Teresa Dias, Carlos Borges, Ana Isabel Rodrigues, Maria do Céu Costa, Adriano Teixeira, Hélder Mota-Filipe. The opposing effects of the flavonoids isoquercitrin and sissotrin, isolated from Pterospartum tridentatum, on oral glucose tolerance in rats. Phytotherapy research : PTR. 2008 Apr; 22(4):539-43. doi: 10.1002/ptr.2403. [PMID: 18338765]
  • E Reis, M T Batista, J M Canhoto. Effect and analysis of phenolic compounds during somatic embryogenesis induction in Feijoa sellowiana Berg. Protoplasma. 2008; 232(3-4):193-202. doi: 10.1007/s00709-008-0290-2. [PMID: 18767216]
  • Ka-Wing Cheng, Qingli Wu, Zong Ping Zheng, Xiaofang Peng, James E Simon, Feng Chen, Mingfu Wang. Inhibitory effect of fruit extracts on the formation of heterocyclic amines. Journal of agricultural and food chemistry. 2007 Dec; 55(25):10359-65. doi: 10.1021/jf071820z. [PMID: 18004801]
  • Marnie L Olson, Margaret E Kargacin, Christopher A Ward, Gary J Kargacin. Effects of phloretin and phloridzin on Ca2+ handling, the action potential, and ion currents in rat ventricular myocytes. The Journal of pharmacology and experimental therapeutics. 2007 Jun; 321(3):921-9. doi: 10.1124/jpet.107.121111. [PMID: 17377061]
  • Xin Zhong Zhang, Yong Bo Zhao, Chun Min Li, Dong Mei Chen, Guang Peng Wang, Rui Feng Chang, Huai Rui Shu. Potential polyphenol markers of phase change in apple (Malus domestica). Journal of plant physiology. 2007 May; 164(5):574-80. doi: 10.1016/j.jplph.2006.03.011. [PMID: 16647787]
  • Marnie L Olson, Margaret E Kargacin, Thomas W Honeyman, Christopher A Ward, Gary J Kargacin. Effects of phytoestrogens on sarcoplasmic/endoplasmic reticulum calcium ATPase 2a and Ca2+ uptake into cardiac sarcoplasmic reticulum. The Journal of pharmacology and experimental therapeutics. 2006 Feb; 316(2):628-35. doi: 10.1124/jpet.105.092940. [PMID: 16227472]
  • Akira Ikari, Yoshiaki Nagatani, Mitsutoshi Tsukimoto, Hitoshi Harada, Masao Miwa, Kuniaki Takagi. Sodium-dependent glucose transporter reduces peroxynitrite and cell injury caused by cisplatin in renal tubular epithelial cells. Biochimica et biophysica acta. 2005 Nov; 1717(2):109-17. doi: 10.1016/j.bbamem.2005.10.003. [PMID: 16288972]
  • C Puel, A Quintin, J Mathey, C Obled, M J Davicco, P Lebecque, S Kati-Coulibaly, M N Horcajada, V Coxam. Prevention of bone loss by phloridzin, an apple polyphenol, in ovariectomized rats under inflammation conditions. Calcified tissue international. 2005 Nov; 77(5):311-8. doi: 10.1007/s00223-005-0060-5. [PMID: 16307390]
  • Ed Etxeberria, Pedro González, Patricia Tomlinson, Javier Pozueta-Romero. Existence of two parallel mechanisms for glucose uptake in heterotrophic plant cells. Journal of experimental botany. 2005 Jul; 56(417):1905-12. doi: 10.1093/jxb/eri185. [PMID: 15911561]
  • Owen Chan, Karen Inouye, Eitan M Akirav, Edward Park, Michael C Riddell, Stephen G Matthews, Mladen Vranic. Hyperglycemia does not increase basal hypothalamo-pituitary-adrenal activity in diabetes but it does impair the HPA response to insulin-induced hypoglycemia. American journal of physiology. Regulatory, integrative and comparative physiology. 2005 Jul; 289(1):R235-46. doi: 10.1152/ajpregu.00674.2004. [PMID: 15774766]
  • Sanjay A Desai, Abdulnaser Alkhalil, Myungsa Kang, Umar Ashfaq, My-Le Nguyen. Plasmodial surface anion channel-independent phloridzin resistance in Plasmodium falciparum. The Journal of biological chemistry. 2005 Apr; 280(17):16861-7. doi: 10.1074/jbc.m414629200. [PMID: 15701633]
  • Akira Ikari. [Regulatory mechanisms of intracellular distribution of Na+-dependent glucose transporter and the role in recovery from cellular injury]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2004 Dec; 124(12):959-64. doi: 10.1248/yakushi.124.959. [PMID: 15577265]
  • Hong Zhao, Shoshana Yakar, Oksana Gavrilova, Hui Sun, Yang Zhang, Hyunsook Kim, Jennifer Setser, William Jou, Derek LeRoith. Phloridzin improves hyperglycemia but not hepatic insulin resistance in a transgenic mouse model of type 2 diabetes. Diabetes. 2004 Nov; 53(11):2901-9. doi: 10.2337/diabetes.53.11.2901. [PMID: 15504971]
  • Raul C Camacho, Joshua C Denny, R Richard Pencek, Yoshiharu Koyama, D Brooks Lacy, Freyja D James, David H Wasserman. Portal venous hyperinsulinemia does not stimulate gut glucose absorption in the conscious dog. Metabolism: clinical and experimental. 2004 Oct; 53(10):1290-5. doi: 10.1016/j.metabol.2004.07.002. [PMID: 15375784]
  • Raul C Camacho, D Brooks Lacy, Freyja D James, Robert H Coker, David H Wasserman. Hepatic glucose autoregulation: responses to small, non-insulin-induced changes in arterial glucose. American journal of physiology. Endocrinology and metabolism. 2004 Aug; 287(2):E269-74. doi: 10.1152/ajpendo.00040.2004. [PMID: 15053988]
  • Kyla M Smith, Amy M L Ng, Sylvia Y M Yao, Kathy A Labedz, Edward E Knaus, Leonard I Wiebe, Carol E Cass, Stephen A Baldwin, Xing-Zhen Chen, Edward Karpinski, James D Young. Electrophysiological characterization of a recombinant human Na+-coupled nucleoside transporter (hCNT1) produced in Xenopus oocytes. The Journal of physiology. 2004 Aug; 558(Pt 3):807-23. doi: 10.1113/jphysiol.2004.068189. [PMID: 15194733]
  • Fabio Chinnici, Alessandra Bendini, Anna Gaiani, Claudio Riponi. Radical scavenging activities of peels and pulps from cv. Golden Delicious apples as related to their phenolic composition. Journal of agricultural and food chemistry. 2004 Jul; 52(15):4684-9. doi: 10.1021/jf049770a. [PMID: 15264900]
  • Wei-Min Yang, Ji-Kai Liu, Xiang-Dong Qin, Wan-Lin Wu, Zhi-He Chen. Antioxidant activities of three dihydrochalcone glucosides from leaves of Lithocarpus pachyphyllus. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2004 Jul; 59(7-8):481-4. doi: 10.1515/znc-2004-7-805. [PMID: 15813365]
  • Jeanelle Boyer, Rui Hai Liu. Apple phytochemicals and their health benefits. Nutrition journal. 2004 May; 3(?):5. doi: 10.1186/1475-2891-3-5. [PMID: 15140261]
  • Silvina B Lotito, Balz Frei. Relevance of apple polyphenols as antioxidants in human plasma: contrasting in vitro and in vivo effects. Free radical biology & medicine. 2004 Jan; 36(2):201-11. doi: 10.1016/j.freeradbiomed.2003.10.005. [PMID: 14744632]
  • Akira Ikari, Mika Nakano, Mihoko Ishibashi, Kazuya Kawano, Yasunobu Suketa, Hitoshi Harada, Kuniaki Takagi. Recovery from heat shock injury by activation of Na+-glucose cotransporter in renal epithelial cells. Biochimica et biophysica acta. 2003 Dec; 1643(1-3):47-53. doi: 10.1016/j.bbamcr.2003.09.001. [PMID: 14654227]
  • Thomas Walle, U Kristina Walle. The beta-D-glucoside and sodium-dependent glucose transporter 1 (SGLT1)-inhibitor phloridzin is transported by both SGLT1 and multidrug resistance-associated proteins 1/2. Drug metabolism and disposition: the biological fate of chemicals. 2003 Nov; 31(11):1288-91. doi: 10.1124/dmd.31.11.1288. [PMID: 14570756]
  • Tatiana Blasco, José J Aramayona, Ana I Alcalde, Julia Catalán, Manuel Sarasa, Victor Sorribas. Rat kidney MAP17 induces cotransport of Na-mannose and Na-glucose in Xenopus laevis oocytes. American journal of physiology. Renal physiology. 2003 Oct; 285(4):F799-810. doi: 10.1152/ajprenal.00149.2003. [PMID: 12812916]
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