Exact Mass: 160.0557972

Pimelic acid, also known as heptanedioic acid is a dicarboxylic acid. Derivatives of pimelic acid are involved in the biosynthesis of the amino acid called lysine. Pimelic acid is one methylene longer than a related dicarboxylic acid, adipic acid, a precursor to many polyesters and polyamides. Pimelic acid is essential for the synthesis of biotin (also called vitamin B7). Biotin is a heterocyclic, S-containing monocarboxylic acid that is made from two precursors, alanine and pimeloyl-CoA. Biotin is important in fatty acid synthesis, branched-chain amino acid catabolism, and gluconeogenesis. Biotin is found in a wide range of foods. Likewise, intestinal bacteria synthesize biotin, which is then absorbed by the host animal. Pimelic acid (which is the precursor for pimeloyl-CoA) is synthesized in many bacteria via a head-to-tail incorporation of acetate units through a modified fatty acid synthetic pathway using O-methyl esters disguised to resemble the canonical intermediates of the fatty acid synthetic pathway (PMID:21435937). Some bacteria and yeast synthesize pimelic acid not by biosynthesis, but via cleavage of longer chain fatty acids (such as linolenic acid) via a cytochrome P450-like enzyme (PMID:28196402, 21435937, 3236079). Pimelic acid is excreted in elevated amounts in the urine of individuals with mitochondrial beta-oxidation disorders and peroxisomal beta oxidation disorders (PMID:1527989) A group of compounds that are derivatives of heptanedioic acid with the general formula R-C7H11O4. KEIO_ID P063 Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine. Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine.

Formiminoaspartate

N-formimidoyl-L-aspartic acid

KEIO_ID F025

Naphthalene-1,2-diol

1,2-Dihydroxynaphthalene monohydrate

This compound belongs to the family of Naphthols and Derivatives. These are hydroxylated naphthalenes.

1-formylindan-2-one

2,3-Naphthalenediol

2,3-Dihydroxynaphthalene

2-Formyl-1-indanone

3,4-Dihydroxycyclohexanecarboxylic acid

(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylic acid

Tricholomic acid

alpha-Amino-3-oxo-5-isoxazolidineacetic acid, (r*,s*)-isomer

Tricholomic acid is found in mushrooms. Tricholomic acid is a constituent of the mushroom Tricholoma muscarium. Said to be useful as a flavouring substance Constituent of the mushroom Tricholoma muscarium. Said to be useful as a flavouring substance. Tricholomic acid is found in mushrooms.

1,4-Dihydroxynaphthalene

2-PSA

2-PROPYL SUCCINIC ACID

NSC109547

4-Hydroxy-1-nitroso-L-proline

(Z)-2-methylureidoacrylate peracid

(2Z)-3-[(C-hydroxycarbonimidoyl)amino]-2-methylprop-2-eneperoxoic acid

(z)-2-methyl-ureidoacrylate peracid, also known as (Z)-2-methylureidoperacrylic acid, is a member of the class of compounds known as peroxycarboxylic acids. Peroxycarboxylic acids are organic acids with the general formula [H]OOC(R)=O (R = H, organyl group) (z)-2-methyl-ureidoacrylate peracid is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). (z)-2-methyl-ureidoacrylate peracid can be found in a number of food items such as pepper (spice), narrowleaf cattail, sweet rowanberry, and european plum, which makes (z)-2-methyl-ureidoacrylate peracid a potential biomarker for the consumption of these food products (z)-2-methyl-ureidoacrylate peracid may be a unique E.coli metabolite.

3-Oxo-3-ureidoisobutyrate

6-Methylcoumarin

5-Methyl-2-hydroxyphenylpropenoic acid lactone

6-methylcoumarin appears as white crystals with a flavor of vanilla. Insoluble in water. (NTP, 1992) 6-methylcoumarin is a member of the class of coumarins that is coumarin in which the hydrogen at position 6 is replaced by a methyl group. It has a role as a fragrance and an allergen. 6-Methylcoumarin is used as a food additive [EAFUS] ("EAFUS: Everything Added to Food in the United States. [http://www.eafus.com/]") A member of the class of coumarins that is coumarin in which the hydrogen at position 6 is replaced by a methyl group.

2,2-Dimethylglutaric acid

2,2-Dimethylpentanedioic acid

2,2-Dimethylglutaric acid belongs to the class of organic compounds known as methyl-branched fatty acids. These are fatty acids with an acyl chain that has a methyl branch. Usually, they are saturated and contain only one or more methyl group. However, branches other than methyl may be present.

3,3-Dimethylglutaric acid

3,3-Dimethylpentanedioic acid

3,3-Dimethylglutaric acid is a compound that has occasionally found in human urine. (PMID: 699273) [HMDB] 3,3-Dimethylglutaric acid is a compound that has occasionally found in human urine. (PMID: 699273). 3,3-Dimethylglutaric acid, a member of methyl-branched fatty acids, is a endogenous metabolite occasionally found in human urine[1].

3-methyladipate

(3S)-3-methylhexanedioic acid

3-Methyladipic acid is a metabolite of the catabolism of phytanic acid. Patients with adult Refsums disease (ARD) are unable to detoxify phytanic acid by alpha-oxidation, and so the w-oxidation pathway is the only metabolic pathway available for phytanic acid degradation. This pathway produces 3-methyladipic acid as the final metabolite, which is excreted in the urine (Wanders et al. 2001). Activity of the w-oxidation pathway is approximately doubled in ARD patients compared with normal individuals (PMID: 11948235). [HMDB] 3-Methyladipic acid is a metabolite of the catabolism of phytanic acid. Patients with adult Refsums disease (ARD) are unable to detoxify phytanic acid by alpha-oxidation, and so the w-oxidation pathway is the only metabolic pathway available for phytanic acid degradation. This pathway produces 3-methyladipic acid as the final metabolite, which is excreted in the urine (Wanders et al. 2001). Activity of the w-oxidation pathway is approximately doubled in ARD patients compared with normal individuals (PMID: 11948235). 3-Methyladipic acid is the final metabolite in the ω-oxidation pathway.

Diethyl malonate

Methanedicarboxylic acid, diethyl ester

Diethyl malonate, also known as dicarbethoxymethane or ethyl propanedioate, belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups. Diethyl malonate is a sweet, apple, and fruity tasting compound. Diethyl malonate has been detected, but not quantified, in a few different foods, such as alcoholic beverages, evergreen blackberries, and fruits. Like other esters, this compound can undergo bromination at the alpha position. Fischer esterification gives diethyl malonate: One of the principal uses of this compound is in the malonic ester synthesis. It occurs naturally in grapes and strawberries as a colourless liquid with an apple-like odour, and is used in perfumes. Malonic acid is a rather simple dicarboxylic acid, with the two carboxyl groups close together. The hydrogen atoms on a carbon adjacent to two carbonyl groups are even more acidic because the carbonyl groups help stabilize the carbanion resulting from the removal of that proton. Like many other esters, this compound can undergo the Claisen ester condensation. This alkylated 1,3-dicarbonyl compound (3) readily undergoes decarboxylation with loss of carbon dioxide, to give a substituted acetic acid, using Sodium ethoxide as the preferred base. The use of aqueous sodium hydroxide may give the base hydrolysis products: sodium malonate and ethanol. Diethyl malonate is a flavouring ingredient. It is a rather simple dicarboxylic acid, with two carboxyl groups close together in its molecule. In forming diethyl malonate from malonic acid, the hydroxyl group (-OH) on both of the carboxyl groups is replaced by an ethoxy group (-OEt; -OCH2CH3). The methylene group (-CH2-) in the middle of the malonic part of the diethyl malonate molecule is neighboured by two carbonyl groups (-C(=O)-). Diethyl malonate is found in alcoholic beverages such as wines, and in fruits such as guava, melon, concord grape, pineapple, blackberry.

Mono-methyl-adipate

Monomethyl 1,6-hexanedioic acid

mono-methyl-adipate, or monomethyl adipate (CAS Number: 627-91-8), is a clear colorless liquid with a low (7-9 C) melting point and 162 C boiling point.

Viburtinal

4-Methylcyclopenta[c]pyran-7-carboxaldehyde, 9ci

Viburtinal is found in fruits. Viburtinal is produced from the hydrolysis of esters present in Viburnum opulus (cranberry bush Production from the hydrolysis of esters present in Viburnum opulus (cranberry bush). Viburtinal is found in fruits.

2-Methyladipic acid

2-Methylhexanedioic acid

not found

7-Methyl-2-benzofurancarboxaldehyde

7-methyl-1-benzofuran-2-carbaldehyde

7-Methyl-2-benzofurancarboxaldehyde is a flavour enhancer for coffee. Flavour enhancer for coffee

Propyleneglycol diacetate

1-(acetyloxy)propan-2-yl acetate

Propyleneglycol diacetate is found in Cucumis melo [Goodscents]. Found in Cucumis melo [Goodscents]

Thymine glycol

5,6-Dihydroxy-5-methyldihydropyrimidine-2,4(1H,3H)-dione

Thymine glycol belongs to the family of Hydropyrimidines. These are compounds containing an hydrogenated pyrimidine ring (i.e containing less than the maximum bumber of double bonds.).

2-Ethylglutaric acid

2-ethylpentanedioic acid

2-Ethylglutaric acid belongs to the family of Branched Fatty Acids. These are fatty acids containing a branched chain.

Ethyl methyl_succinate

1-Ethyl 4-methyl butanedioic acid