Cinchonain 1a (BioDeep_00001883370)

Main id: BioDeep_00000007943

 

PANOMIX_OTCML-2023


代谢物信息卡片


Cinchonain 1a

化学式: C24H20O9 (452.1107)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C(C(OC2=C1C(=CC3=C2C(CC(=O)O3)C4=CC(=C(C=C4)O)O)O)C5=CC(=C(C=C5)O)O)O
InChI: InChI=1S/C24H20O9/c25-14-3-1-10(5-17(14)28)12-8-21(31)32-20-9-16(27)13-7-19(30)23(33-24(13)22(12)20)11-2-4-15(26)18(29)6-11/h1-6,9,12,19,23,25-30H,7-8H2/t12-,19-,23-/m1/s1

描述信息

同义名列表

3 个代谢物同义名

Cinchonain 1a; cinchonain Ia; Cinchonain 1a



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

9 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 MYD88, PIK3R1, PTGS2, TLR4
Peripheral membrane protein 1 PTGS2
Endosome membrane 2 MYD88, TLR4
Endoplasmic reticulum membrane 1 PTGS2
Nucleus 2 MYD88, PIK3R1
cytosol 2 MYD88, PIK3R1
Cell membrane 1 TLR4
cell surface 2 MYD88, TLR4
Golgi membrane 1 INS
plasma membrane 3 MYD88, PIK3R1, TLR4
Membrane 2 PIK3R1, TLR4
caveola 1 PTGS2
endoplasmic reticulum 1 PTGS2
extracellular space 4 IL17A, IL4, IL6, INS
perinuclear region of cytoplasm 2 PIK3R1, TLR4
protein-containing complex 2 MYD88, PTGS2
Microsome membrane 1 PTGS2
Single-pass type I membrane protein 1 TLR4
Secreted 4 IL17A, IL4, IL6, INS
extracellular region 4 IL17A, IL4, IL6, INS
external side of plasma membrane 2 IL17A, TLR4
Early endosome 1 TLR4
cell-cell junction 1 PIK3R1
cis-Golgi network 1 PIK3R1
perinuclear endoplasmic reticulum membrane 1 PIK3R1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Cell projection, ruffle 1 TLR4
ruffle 1 TLR4
receptor complex 1 TLR4
neuron projection 1 PTGS2
phagocytic cup 1 TLR4
endosome lumen 1 INS
lipopolysaccharide receptor complex 1 TLR4
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 IL6, INS, PTGS2
phosphatidylinositol 3-kinase complex 1 PIK3R1
phosphatidylinositol 3-kinase complex, class IA 1 PIK3R1
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
extrinsic component of cytoplasmic side of plasma membrane 1 MYD88
extrinsic component of plasma membrane 1 MYD88
interleukin-6 receptor complex 1 IL6


文献列表

  • Ana Luiza Sereia, Renata Longhini, Gisely Cristiny Lopes, João Carlos Palazzo de Mello. Capillary Electrophoresis as Tool for Diastereomeric Separation in a Trichilia catigua Fraction. Phytochemical analysis : PCA. 2017 May; 28(3):144-150. doi: 10.1002/pca.2653. [PMID: 27910216]
  • Fadi Qa'dan, Eugen J Verspohl, Adolf Nahrstedt, Frank Petereit, Khalid Z Matalka. Cinchonain Ib isolated from Eriobotrya japonica induces insulin secretion in vitro and in vivo. Journal of ethnopharmacology. 2009 Jul; 124(2):224-7. doi: 10.1016/j.jep.2009.04.023. [PMID: 19397981]
  • Wanxia Tang, Hideaki Hioki, Kenichi Harada, Miwa Kubo, Yoshiyasu Fukuyama. Antioxidant phenylpropanoid-substituted epicatechins from Trichilia catigua. Journal of natural products. 2007 Dec; 70(12):2010-3. doi: 10.1021/np0703895. [PMID: 18020420]
  • Flávio Luís Beltrame, Edson Rodrigues Filho, Fabio A Proença Barros, Diógenes Aparíciogarcia Cortez, Quezia Bezerra Cass. A validated higher-performance liquid chromatography method for quantification of cinchonain Ib in bark and phytopharmaceuticals of Trichilia catigua used as Catuaba. Journal of chromatography. A. 2006 Jun; 1119(1-2):257-63. doi: 10.1016/j.chroma.2005.10.050. [PMID: 16360665]