Durene (BioDeep_00001874265)
Main id: BioDeep_00000009960
代谢物信息卡片
1,2,4,5-TETRAMETHYLBENZENE
化学式: C10H14 (134.1095444)
中文名称: 1,2,4,5-四甲苯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC(=C(C=C1C)C)C
InChI: InChI=1S/C10H14/c1-7-5-9(3)10(4)6-8(7)2/h5-6H,1-4H3
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:38978
- KEGG: C14534
- PubChem: 7269
- ChEMBL: CHEMBL1797134
- CAS: 95-93-2
- PubChem: 17395534
- NIKKAJI: J4.714G
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Francis Jacob, Kristjan Ukegjini, Sheri Nixdorf, Caroline E Ford, Jake Olivier, Rosmarie Caduff, James P Scurry, Rea Guertler, Daniela Hornung, Renato Mueller, Daniel A Fink, Neville F Hacker, Viola A Heinzelmann-Schwarz. Loss of secreted frizzled-related protein 4 correlates with an aggressive phenotype and predicts poor outcome in ovarian cancer patients.
PloS one.
2012; 7(2):e31885. doi:
10.1371/journal.pone.0031885. [PMID: 22363760] - Ying Qin, Ya-Ping Tian. Protective effects of total glucosides of paeony and the underlying mechanisms in carbon tetrachloride-induced experimental liver injury.
Archives of medical science : AMS.
2011 Aug; 7(4):604-12. doi:
10.5114/aoms.2011.24129. [PMID: 22291795] - K Boutabet, W Kebsa, M Alyane, M Lahouel. Polyphenolic fraction of Algerian propolis protects rat kidney against acute oxidative stress induced by doxorubicin.
Indian journal of nephrology.
2011 Apr; 21(2):101-6. doi:
10.4103/0971-4065.82131. [PMID: 21769172] - Tatiana V Komarova, Vyacheslav S Kosorukov, Olga Y Frolova, Igor V Petrunia, Ksenia A Skrypnik, Yuri Y Gleba, Yuri L Dorokhov. Plant-made trastuzumab (herceptin) inhibits HER2/Neu+ cell proliferation and retards tumor growth.
PloS one.
2011 Mar; 6(3):e17541. doi:
10.1371/journal.pone.0017541. [PMID: 21390232] - Hironori Kobayashi, Hideki Takase, Yumiko Suzuki, Fumiko Tanzawa, Ryoji Takata, Keiko Fujita, Minako Kohno, Mai Mochizuki, Shunji Suzuki, Tomonori Konno. Environmental stress enhances biosynthesis of flavor precursors, S-3-(hexan-1-ol)-glutathione and S-3-(hexan-1-ol)-L-cysteine, in grapevine through glutathione S-transferase activation.
Journal of experimental botany.
2011 Jan; 62(3):1325-36. doi:
10.1093/jxb/erq376. [PMID: 21115666] - Teru Kanda, Sachiko Shibata, Satoru Saito, Takayuki Murata, Hiroki Isomura, Hironori Yoshiyama, Kenzo Takada, Tatsuya Tsurumi. Unexpected instability of family of repeats (FR), the critical cis-acting sequence required for EBV latent infection, in EBV-BAC systems.
PloS one.
2011; 6(11):e27758. doi:
10.1371/journal.pone.0027758. [PMID: 22114684] - Bennett Young, Raymond Wightman, Robert Blanvillain, Sydney B Purcel, Patrick Gallois. pH-sensitivity of YFP provides an intracellular indicator of programmed cell death.
Plant methods.
2010 Nov; 6(?):27. doi:
10.1186/1746-4811-6-27. [PMID: 21118545] - Ying Qin, Ya-ping Tian. Exploring the molecular mechanisms underlying the potentiation of exogenous growth hormone on alcohol-induced fatty liver diseases in mice.
Journal of translational medicine.
2010 Nov; 8(?):120. doi:
10.1186/1479-5876-8-120. [PMID: 21087523] - Justine Y Lau, Brian G Oliver, Melissa Baraket, Emma L Beckett, Nicole G Hansbro, Lyn M Moir, Steve D Wilton, Carolyn Williams, Paul S Foster, Philip M Hansbro, Judith L Black, Janette K Burgess. Fibulin-1 is increased in asthma--a novel mediator of airway remodeling?.
PloS one.
2010 Oct; 5(10):e13360. doi:
10.1371/journal.pone.0013360. [PMID: 20967215] - Ying Qin, Ya-ping Tian. Preventive effects of chronic exogenous growth hormone levels on diet-induced hepatic steatosis in rats.
Lipids in health and disease.
2010 Jul; 9(?):78. doi:
10.1186/1476-511x-9-78. [PMID: 20653983] - Stefania Tegli, Matteo Cerboneschi, Ilaria Marsili Libelli, Elena Santilli. Development of a versatile tool for the simultaneous differential detection of Pseudomonas savastanoi pathovars by End Point and Real-Time PCR.
BMC microbiology.
2010 May; 10(?):156. doi:
10.1186/1471-2180-10-156. [PMID: 20509893] - I Dahlman, N Mejhert, K Linder, T Agustsson, D M Mutch, A Kulyte, B Isaksson, J Permert, N Petrovic, J Nedergaard, E Sjölin, D Brodin, K Clement, K Dahlman-Wright, M Rydén, P Arner. Adipose tissue pathways involved in weight loss of cancer cachexia.
British journal of cancer.
2010 May; 102(10):1541-8. doi:
10.1038/sj.bjc.6605665. [PMID: 20407445] - Toru Takahashi, Kazuma Takahashi, Mitsuhiro Yamashina, Chihaya Maesawa, Takashi Kajiwara, Haruhito Taneichi, Noriko Takebe, Yoshihito Kaneko, Tomoyuki Masuda, Jo Satoh. Association of the TNF-{alpha}-C-857T polymorphism with resistance to the cholesterol-lowering effect of HMG-CoA reductase inhibitors in type 2 diabetic subjects.
Diabetes care.
2010 Mar; 33(3):463-6. doi:
10.2337/dc09-1724. [PMID: 20007938] - Niklas Mejhert, Jurga Laurencikiene, Amanda T Pettersson, Maria Kaaman, Britta M Stenson, Mikael Rydén, Ingrid Dahlman. Role of Receptor-Interacting Protein 140 in human fat cells.
BMC endocrine disorders.
2010 Jan; 10(?):1. doi:
10.1186/1472-6823-10-1. [PMID: 20205832] - Lee D Roberts, David G Hassall, Deborah A Winegar, John N Haselden, Andrew W Nicholls, Julian L Griffin. Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor delta from Peroxisome proliferator-activated receptor gamma in the ob/ob mouse.
Genome medicine.
2009 Dec; 1(12):115. doi:
10.1186/gm115. [PMID: 19968882] - Anthony Arguelles-Arias, Marc Ongena, Badre Halimi, Yannick Lara, Alain Brans, Bernard Joris, Patrick Fickers. Bacillus amyloliquefaciens GA1 as a source of potent antibiotics and other secondary metabolites for biocontrol of plant pathogens.
Microbial cell factories.
2009 Nov; 8(?):63. doi:
10.1186/1475-2859-8-63. [PMID: 19941639] - Sini Junttila, Kean-Jin Lim, Stephen Rudd. Optimization and comparison of different methods for RNA isolation for cDNA library construction from the reindeer lichen Cladonia rangiferina.
BMC research notes.
2009 Oct; 2(?):204. doi:
10.1186/1756-0500-2-204. [PMID: 19804636] - Claudia H T Tam, Ronald C W Ma, Wing Yee So, Ying Wang, Vincent K L Lam, Soren Germer, Mitchell Martin, Juliana C N Chan, Maggie C Y Ng. Interaction effect of genetic polymorphisms in glucokinase (GCK) and glucokinase regulatory protein (GCKR) on metabolic traits in healthy Chinese adults and adolescents.
Diabetes.
2009 Mar; 58(3):765-9. doi:
10.2337/db08-1277. [PMID: 19073768] - Yasuharu Tabara, Haruhiko Osawa, Ryuichi Kawamoto, Hiroshi Onuma, Ikki Shimizu, Tetsuro Miki, Katsuhiko Kohara, Hideichi Makino. Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening.
Diabetes.
2009 Feb; 58(2):493-8. doi:
10.2337/db07-1785. [PMID: 19033397] - Dawn K Coletta, Jennifer Schneider, Shirley L Hu, Thomas D Dyer, Sobha Puppala, Vidya S Farook, Rector Arya, Donna M Lehman, John Blangero, Ralph A DeFronzo, Ravindranath Duggirala, Christopher P Jenkinson. Genome-wide linkage scan for genes influencing plasma triglyceride levels in the Veterans Administration Genetic Epidemiology Study.
Diabetes.
2009 Jan; 58(1):279-84. doi:
10.2337/db08-0491. [PMID: 18931038] - Luigi Gennari, Daniela Merlotti, Vincenzo De Paola, Giuseppe Martini, Ranuccio Nuti. Bazedoxifene for the prevention of postmenopausal osteoporosis.
Therapeutics and clinical risk management.
2008 Dec; 4(6):1229-42. doi:
10.2147/tcrm.s3476. [PMID: 19337430] - Marju Orho-Melander, Olle Melander, Candace Guiducci, Pablo Perez-Martinez, Dolores Corella, Charlotta Roos, Ryan Tewhey, Mark J Rieder, Jennifer Hall, Goncalo Abecasis, E Shyong Tai, Cullan Welch, Donna K Arnett, Valeriya Lyssenko, Eero Lindholm, Richa Saxena, Paul I W de Bakker, Noel Burtt, Benjamin F Voight, Joel N Hirschhorn, Katherine L Tucker, Thomas Hedner, Tiinamaija Tuomi, Bo Isomaa, Karl-Fredrik Eriksson, Marja-Riitta Taskinen, Björn Wahlstrand, Thomas E Hughes, Laurence D Parnell, Chao-Qiang Lai, Göran Berglund, Leena Peltonen, Erkki Vartiainen, Pekka Jousilahti, Aki S Havulinna, Veikko Salomaa, Peter Nilsson, Leif Groop, David Altshuler, Jose M Ordovas, Sekar Kathiresan. Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations.
Diabetes.
2008 Nov; 57(11):3112-21. doi:
10.2337/db08-0516. [PMID: 18678614] - Lu Qi, Kihwa Kang, Cuilin Zhang, Rob M van Dam, Peter Kraft, David Hunter, Chih-Hao Lee, Frank B Hu. Fat mass-and obesity-associated (FTO) gene variant is associated with obesity: longitudinal analyses in two cohort studies and functional test.
Diabetes.
2008 Nov; 57(11):3145-51. doi:
10.2337/db08-0006. [PMID: 18647953] - Niels Grarup, Gitte Andersen, Nikolaj T Krarup, Anders Albrechtsen, Ole Schmitz, Torben Jørgensen, Knut Borch-Johnsen, Torben Hansen, Oluf Pedersen. Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.
Diabetes.
2008 Sep; 57(9):2534-40. doi:
10.2337/db08-0436. [PMID: 18567820] - Joshua P Lewis, Nicholette D Palmer, Pamela J Hicks, Michele M Sale, Carl D Langefeld, Barry I Freedman, Jasmin Divers, Donald W Bowden. Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies.
Diabetes.
2008 Aug; 57(8):2220-5. doi:
10.2337/db07-1319. [PMID: 18443202] - Hoang Hoa Long, Dominik D Schmidt, Ian T Baldwin. Native bacterial endophytes promote host growth in a species-specific manner; phytohormone manipulations do not result in common growth responses.
PloS one.
2008 Jul; 3(7):e2702. doi:
10.1371/journal.pone.0002702. [PMID: 18628963] - Elliot S Stolerman, Alisa K Manning, Jarred B McAteer, Josée Dupuis, Caroline S Fox, L Adrienne Cupples, James B Meigs, Jose C Florez. Haplotype structure of the ENPP1 Gene and Nominal Association of the K121Q missense single nucleotide polymorphism with glycemic traits in the Framingham Heart Study.
Diabetes.
2008 Jul; 57(7):1971-7. doi:
10.2337/db08-0266. [PMID: 18426862] - Yan Li, Jakub Sroubek, Yamini Krishnan, Thomas V McDonald. A-kinase anchoring protein targeting of protein kinase A and regulation of HERG channels.
The Journal of membrane biology.
2008 May; 223(2):107-16. doi:
10.1007/s00232-008-9118-4. [PMID: 18679741] - Lene T Olsen, Hege H Divon, Ronald Al, Kjetil Fosnes, Stein Erik Lid, Hilde-Gunn Opsahl-Sorteberg. The defective seed5 (des5) mutant: effects on barley seed development and HvDek1, HvCr4, and HvSal1 gene regulation.
Journal of experimental botany.
2008; 59(13):3753-65. doi:
10.1093/jxb/ern228. [PMID: 18791195] - Rong Tsao, Frieda E Romanchuk, Chris J Peterson, Joel R Coats. Plant growth regulatory effect and insecticidal activity of the extracts of the Tree of Heaven (Ailanthus altissima L.).
BMC ecology.
2002; 2(?):1. doi:
10.1186/1472-6785-2-1. [PMID: 11860616] - D F Shakirov. [Microsomal monooxygenases upon inhalation exposure to pseudocumene and durene].
Gigiena i sanitariia.
2001 Jul; ?(4):53-6. doi:
. [PMID: 11530642] - D Ligocka, A Sapota, K Rydzynski. The disposition and metabolism of durene (1,2,4,5-tetramethylbenzene) in rats.
Archives of toxicology.
2001 Jan; 74(11):673-9. doi:
10.1007/s002040000165. [PMID: 11218043]