Amyl nitrite (BioDeep_00001868064)

Main id: BioDeep_00000006503

 


代谢物信息卡片


Isopentyl nitrite

化学式: C5H11NO2 (117.079)
中文名称: 亚硝酸异戊酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)CCON=O
InChI: InChI=1S/C5H11NO2/c1-5(2)3-4-8-6-7/h5H,3-4H2,1-2H3

描述信息

C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent

同义名列表

4 个代谢物同义名

Isopentyl nitrite; Amyl nitrite; Amyl nitrite; Isoamyl nitrite



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ABCB1, CASP3, HIF1A, POMC, TGFB1
Nucleus 3 CASP3, HIF1A, TGFB1
cytosol 3 CASP3, GPT, HIF1A
nuclear body 1 HIF1A
nucleoplasm 2 CASP3, HIF1A
RNA polymerase II transcription regulator complex 1 HIF1A
Cell membrane 2 ABCB1, OXTR
Multi-pass membrane protein 3 ABCB1, OXTR, SLC9C1
Synapse 1 CRH
cell surface 3 ABCB1, ADIPOQ, TGFB1
glutamatergic synapse 1 CASP3
neuronal cell body 2 CASP3, TGFB1
plasma membrane 4 ABCB1, OXTR, SLC9C1, TGFB1
Membrane 3 ABCB1, OXTR, SLC9C1
apical plasma membrane 2 ABCB1, OXTR
axon 1 TGFB1
extracellular exosome 2 ABCB1, GPT
endoplasmic reticulum 1 ADIPOQ
extracellular space 4 ADIPOQ, CRH, POMC, TGFB1
adherens junction 1 OXTR
protein-containing complex 1 HIF1A
postsynaptic density 1 CASP3
Secreted 4 ADIPOQ, CRH, POMC, TGFB1
extracellular region 5 ADIPOQ, CRH, ELN, POMC, TGFB1
motile cilium 2 HIF1A, SLC9C1
varicosity 1 CRH
Secreted, extracellular space, extracellular matrix 2 ELN, TGFB1
neuronal dense core vesicle lumen 1 CRH
perikaryon 1 CRH
axon cytoplasm 1 HIF1A
Apical cell membrane 1 ABCB1
extracellular matrix 2 ELN, TGFB1
collagen trimer 1 ADIPOQ
collagen-containing extracellular matrix 3 ADIPOQ, ELN, TGFB1
secretory granule 2 POMC, TGFB1
nuclear speck 1 HIF1A
chromatin 1 HIF1A
blood microparticle 1 TGFB1
microvillus 1 OXTR
Cell projection, cilium, flagellum membrane 1 SLC9C1
Nucleus speckle 1 HIF1A
euchromatin 1 HIF1A
secretory granule lumen 1 POMC
Golgi lumen 1 TGFB1
platelet alpha granule lumen 1 TGFB1
external side of apical plasma membrane 1 ABCB1
death-inducing signaling complex 1 CASP3
elastic fiber 1 ELN
[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix 1 TGFB1
[Transforming growth factor beta-1]: Secreted 1 TGFB1


文献列表

  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Ruri Kikura-Hanajiri, Nahoko Uchiyama, Maiko Kawamura, Jun Ogata, Yukihiro Goda. [Prevalence of new designer drugs and their legal status in Japan]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2013; 133(1):31-40. doi: 10.1248/yakushi.12-00247-6. [PMID: 23292017]
  • Ioannis S Minas, Georgia Tanou, Maya Belghazi, Dominique Job, George A Manganaris, Athanassios Molassiotis, Miltiadis Vasilakakis. Physiological and proteomic approaches to address the active role of ozone in kiwifruit post-harvest ripening. Journal of experimental botany. 2012 Apr; 63(7):2449-64. doi: 10.1093/jxb/err418. [PMID: 22268155]
  • Ming J Wu, Patrick J O'Doherty, Patricia A Murphy, Victoria Lyons, Melinda Christophersen, Peter J Rogers, Trevor D Bailey, Vincent J Higgins. Different reactive oxygen species lead to distinct changes of cellular metal ions in the eukaryotic model organism Saccharomyces cerevisiae. International journal of molecular sciences. 2011; 12(11):8119-32. doi: 10.3390/ijms12118119. [PMID: 22174654]
  • Yu Ishima, Takaaki Akaike, Ulrich Kragh-Hansen, Shuichi Hiroyama, Tomohiro Sawa, Ayaka Suenaga, Toru Maruyama, Toshiya Kai, Masaki Otagiri. S-nitrosylated human serum albumin-mediated cytoprotective activity is enhanced by fatty acid binding. The Journal of biological chemistry. 2008 Dec; 283(50):34966-75. doi: 10.1074/jbc.m807009200. [PMID: 18940810]
  • Naohisa Katayama, Keisuke Nakajou, Hisakazu Komori, Kunitoshi Uchida, Jun-Ichi Yokoe, Norikiyo Yasui, Hisashi Yamamoto, Toshiya Kai, Makoto Sato, Takenobu Nakagawa, Motohiro Takeya, Toru Maruyama, Masaki Otagiri. Design and evaluation of S-nitrosylated human serum albumin as a novel anticancer drug. The Journal of pharmacology and experimental therapeutics. 2008 Apr; 325(1):69-76. doi: 10.1124/jpet.107.132100. [PMID: 18218831]
  • Adrian C Nicolescu, James N Reynolds, L Ross C Barclay, Gregory R J Thatcher. Organic nitrites and NO: inhibition of lipid peroxidation and radical reactions. Chemical research in toxicology. 2004 Feb; 17(2):185-96. doi: 10.1021/tx034097p. [PMID: 14967006]
  • Adrian C Nicolescu, Sergei I Zavorin, Nicholas J Turro, James N Reynolds, Gregory R J Thatcher. Inhibition of lipid peroxidation in synaptosomes and liposomes by nitrates and nitrites. Chemical research in toxicology. 2002 Jul; 15(7):985-98. doi: 10.1021/tx025529j. [PMID: 12119011]
  • V M Ramanathan, T G Reigle, S Muralidhara, C E Dallas. Effects of acute inhalation exposure to isoamyl nitrite on the hypothalamo-pituitary-adrenal axis in male Sprague-Dawley rats. Journal of toxicology and environmental health. Part A. 1998 Nov; 55(5):345-58. doi: 10.1080/009841098158395. [PMID: 9829558]