Dioxane (BioDeep_00000009900)

 

Secondary id: BioDeep_00001871292

human metabolite blood metabolite natural product


代谢物信息卡片


Tetrahydro-para-dioxin

化学式: C4H8O2 (88.0524)
中文名称: 1,4-二氧六环, 二恶烷
谱图信息: 最多检出来源 Homo sapiens(blood) 100%

分子结构信息

SMILES: C1COCCO1
InChI: InChI=1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2

描述信息

同义名列表

17 个代谢物同义名

Tetrahydro-para-dioxin; 1,4-DIETHYLENE dioxide; Tetrahydro-1,4-dioxin; Glycol ethylene ether; 1,4-Dioxacyclohexane; Tetrahydro-p-dioxin; Di(ethylene oxide); Diethylene ether; Dioxane-1,4; 1,4-DIOXANE; Dioxan-1,4; 1,4-Dioxan; p-Dioxane; Dioxane; Dioxan; 1,4-Dioxane; Dioxane



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

15 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 AKR1C4, ALB, CAT, CYP1A1, CYP2E1, GRHPR, HPGDS, MSMP, PMP2, TBX20, TUBB4B
Peripheral membrane protein 3 CYP1A1, CYP1B1, CYP2E1
Endoplasmic reticulum membrane 3 CYP1A1, CYP1B1, CYP2E1
Nucleus 5 ALB, PMP2, TBX20, TUBB4B, ZNF77
cytosol 10 AKR1C4, ALB, CAT, GPT, GRHPR, HAO2, HPGDS, LIPE, PMP2, TUBB4B
dendrite 1 HTR1A
centrosome 1 ALB
nucleoplasm 1 HPGDS
Cell membrane 2 HTR1A, LIPE
Multi-pass membrane protein 1 HTR1A
Synapse 1 HTR1A
Golgi apparatus 1 ALB
mitochondrial inner membrane 2 CYP1A1, CYP2E1
Cytoplasm, cytosol 2 AKR1C4, LIPE
plasma membrane 2 HTR1A, ME3
Membrane 4 CAT, CYP1B1, LIPE, ME3
caveola 1 LIPE
extracellular exosome 8 AKR1C4, ALB, CAT, GPT, GRHPR, LYZ, PMP2, TUBB4B
endoplasmic reticulum 1 ALB
extracellular space 4 ALB, IL6, LYZ, MSMP
mitochondrion 5 CAT, CYP1A1, CYP1B1, GRHPR, ME3
protein-containing complex 2 ALB, CAT
intracellular membrane-bounded organelle 5 CAT, CYP1A1, CYP1B1, CYP2E1, HPGDS
Microsome membrane 3 CYP1A1, CYP1B1, CYP2E1
Secreted 3 ALB, IL6, MSMP
extracellular region 5 ALB, CAT, IL6, LYZ, TUBB4B
Single-pass membrane protein 1 ME3
mitochondrial matrix 2 CAT, ME3
anchoring junction 1 ALB
Extracellular vesicle 1 TUBB4B
microtubule cytoskeleton 1 TUBB4B
Mitochondrion inner membrane 2 CYP1A1, CYP2E1
Cytoplasm, cytoskeleton 1 TUBB4B
focal adhesion 1 CAT
microtubule 1 TUBB4B
Peroxisome 2 CAT, HAO2
Peroxisome matrix 1 CAT
peroxisomal matrix 3 CAT, GRHPR, HAO2
peroxisomal membrane 1 CAT
ciliary basal body 1 ALB
chromatin 1 TBX20
mitotic spindle 1 TUBB4B
cytoskeleton 1 TUBB4B
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
intercellular bridge 1 TUBB4B
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
axonemal microtubule 1 TUBB4B
Cell projection, dendrite 1 HTR1A
myelin sheath 1 PMP2
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 2 ALB, IL6
platelet alpha granule lumen 1 ALB
specific granule lumen 1 LYZ
tertiary granule lumen 1 LYZ
azurophil granule lumen 2 LYZ, TUBB4B
catalase complex 1 CAT
catalytic complex 1 GRHPR
interleukin-6 receptor complex 1 IL6
ciliary transition fiber 1 ALB


文献列表

  • Hadeer Ibrahiem, Ghada Saber M Ismail, Masarrat M Migahid, Mohamed A Ghazy, Mahmoud Nasr. Dual phytoremediation and biochar production by Eichhornia crassipes in hydroponic system receiving different 1,4-dioxane dosages. International journal of phytoremediation. 2024; 26(4):546-556. doi: 10.1080/15226514.2023.2253915. [PMID: 37667465]
  • Amie C McElroy, Matthew E Ogles, Michael R Hyman, Detlef R U Knappe. Pilot-scale biofiltration of 1,4-dioxane at drinking water-relevant concentrations. Water research. 2023 Mar; 231(?):119652. doi: 10.1016/j.watres.2023.119652. [PMID: 36702026]
  • Kazushi Noro, Satoshi Endo, Daisuke Inoue, Natsumi Suzuki, Hiroshi Kameoka, Junko Ono, Satoshi Nakamura, Yoshinori Yabuki. Development of a New Polar Organic Chemical Integrative Sampler for 1,4-dioxane Using Silicone Membrane as a Diffusion Barrier. Environmental toxicology and chemistry. 2023 Feb; 42(2):296-302. doi: 10.1002/etc.5518. [PMID: 36349960]
  • Ying Chen, Yewei Wang, Georgia Charkoftaki, David J Orlicky, Emily Davidson, Fengjie Wan, Gary Ginsberg, David C Thompson, Vasilis Vasiliou. Oxidative stress and genotoxicity in 1,4-dioxane liver toxicity as evidenced in a mouse model of glutathione deficiency. The Science of the total environment. 2022 Feb; 806(Pt 2):150703. doi: 10.1016/j.scitotenv.2021.150703. [PMID: 34600989]
  • Yingning Wang, Fang Ma, Jixian Yang, Haijuan Guo, Delin Su. Xanthobacter dioxanivorans sp. nov., a 1,4-dioxane-degrading bacterium. International journal of systematic and evolutionary microbiology. 2021 Dec; 71(12):. doi: 10.1099/ijsem.0.005139. [PMID: 34882528]
  • Deniz Kurt, Ali Acar, Dilek Çavuşoğlu, Emine Yalçin, Kültiğin Çavuşoğlu. Genotoxic effects and molecular docking of 1,4-dioxane: combined protective effects of trans-resveratrol. Environmental science and pollution research international. 2021 Oct; 28(39):54922-54935. doi: 10.1007/s11356-021-14387-3. [PMID: 34021451]
  • Georgia Charkoftaki, Jaya Prakash Golla, Alvaro Santos-Neto, David J Orlicky, Rolando Garcia-Milian, Ying Chen, Nicholas J W Rattray, Yuping Cai, Yewei Wang, Colin T Shearn, Varvara Mironova, Yensheng Wang, Caroline H Johnson, David C Thompson, Vasilis Vasiliou. Identification of Dose-Dependent DNA Damage and Repair Responses From Subchronic Exposure to 1,4-Dioxane in Mice Using a Systems Analysis Approach. Toxicological sciences : an official journal of the Society of Toxicology. 2021 09; 183(2):338-351. doi: 10.1093/toxsci/kfab030. [PMID: 33693819]
  • Kanji Niwa, Naonobu Tanaka, Yusei Shimomoto, Daisuke Tsuji, Sang-Yong Kim, Mareshige Kojoma, Kohji Itoh, Chin-Ho Chen, Kuo-Hsiung Lee, Yoshiki Kashiwada. Hyperdioxanes, dibenzo-1,4-dioxane derivatives from the roots of Hypericum ascyron. Journal of natural medicines. 2021 Sep; 75(4):907-914. doi: 10.1007/s11418-021-01540-y. [PMID: 34142303]
  • Ruihuan Chen, Yu Miao, Yun Liu, Lan Zhang, Ming Zhong, Jonathan Miles Adams, Yuanhua Dong, Shaily Mahendra. Identification of novel 1,4-dioxane degraders and related genes from activated sludge by taxonomic and functional gene sequence analysis. Journal of hazardous materials. 2021 06; 412(?):125157. doi: 10.1016/j.jhazmat.2021.125157. [PMID: 33540262]
  • Riley A Murnane, Weijue Chen, Michael Hyman, Lewis Semprini. Long-term cometabolic transformation of 1,1,1-trichloroethane and 1,4-dioxane by Rhodococcus rhodochrous ATCC 21198 grown on alcohols slowly produced by orthosilicates. Journal of contaminant hydrology. 2021 Jun; 240(?):103796. doi: 10.1016/j.jconhyd.2021.103796. [PMID: 33765462]
  • Gang Shi, Shota Nishizawa, Taku Matsushita, Yuna Kato, Takahiro Kozumi, Yoshihiko Matsui, Nobutaka Shirasaki. Computational fluid dynamics-based modeling and optimization of flow rate and radiant exitance for 1,4-dioxane degradation in a vacuum ultraviolet photoreactor. Water research. 2021 Jun; 197(?):117086. doi: 10.1016/j.watres.2021.117086. [PMID: 33819661]
  • Yu Miao, Monica B Heintz, Caitlin H Bell, Nicholas W Johnson, Alexandra LaPat Polasko, David Favero, Shaily Mahendra. Profiling microbial community structures and functions in bioremediation strategies for treating 1,4-dioxane-contaminated groundwater. Journal of hazardous materials. 2021 04; 408(?):124457. doi: 10.1016/j.jhazmat.2020.124457. [PMID: 33189472]
  • S Kilo, J Wick, S Mini Vijayan, T Göen, R E Horch, I Ludolph, H Drexler. Impact of physiologically relevant temperatures on dermal absorption of active substances - an ex-vivo study in human skin. Toxicology in vitro : an international journal published in association with BIBRA. 2020 Oct; 68(?):104954. doi: 10.1016/j.tiv.2020.104954. [PMID: 32738276]
  • Qing Zhou, Liujing Jiang, Jingfan Qiu, Yang Pan, Robert V Swanda, Peng Shi, Ai-Min Li, Xiaowei Zhang. Oral Exposure to 1,4-Dioxane Induces Hepatic Inflammation in Mice: The Potential Promoting Effect of the Gut Microbiome. Environmental science & technology. 2020 08; 54(16):10149-10158. doi: 10.1021/acs.est.0c01543. [PMID: 32674564]
  • Kültiğin Çavuşoğlu, Deniz Kurt, Emine Yalçın. A versatile model for investigating the protective effects of Ceratonia siliqua pod extract against 1,4-dioxane toxicity. Environmental science and pollution research international. 2020 Aug; 27(22):27885-27892. doi: 10.1007/s11356-020-08545-2. [PMID: 32405939]
  • Mitchell T Rasmussen, Alyssa M Saito, Michael R Hyman, Lewis Semprini. Co-encapsulation of slow release compounds and Rhodococcus rhodochrous ATCC 21198 in gellan gum beads to promote the long-term aerobic cometabolic transformation of 1,1,1-trichloroethane, cis-1,2-dichloroethene and 1,4-dioxane. Environmental science. Processes & impacts. 2020 Mar; 22(3):771-791. doi: 10.1039/c9em00607a. [PMID: 32083262]
  • Hannah M Rolston, Michael R Hyman, Lewis Semprini. Aerobic cometabolism of 1,4-dioxane by isobutane-utilizing microorganisms including Rhodococcus rhodochrous strain 21198 in aquifer microcosms: Experimental and modeling study. The Science of the total environment. 2019 Dec; 694(?):133688. doi: 10.1016/j.scitotenv.2019.133688. [PMID: 31756820]
  • Zsófia Borbála Rózsa, Lukács József Németh, Balázs Jójárt, Károly Nehéz, Béla Viskolcz, Milán Szőri. Molecular Dynamics and Metadynamics Insights of 1,4-Dioxane-Induced Structural Changes of Biomembrane Models. The journal of physical chemistry. B. 2019 09; 123(37):7869-7884. doi: 10.1021/acs.jpcb.9b04313. [PMID: 31452375]
  • Justin Milavec, Geoffrey R Tick, Mark L Brusseau, Kenneth C Carroll. 1,4-Dioxane cosolvency impacts on trichloroethene dissolution and sorption. Environmental pollution (Barking, Essex : 1987). 2019 Sep; 252(Pt A):777-783. doi: 10.1016/j.envpol.2019.05.156. [PMID: 31200203]
  • Jingfan Qiu, Jiade Cheng, Yanci Xie, Liujing Jiang, Peng Shi, Xinying Li, Robert V Swanda, Jun Zhou, Yong Wang. 1,4-Dioxane exposure induces kidney damage in mice by perturbing specific renal metabolic pathways: An integrated omics insight into the underlying mechanisms. Chemosphere. 2019 Aug; 228(?):149-158. doi: 10.1016/j.chemosphere.2019.04.111. [PMID: 31029960]
  • Naima A Khan, Michael D Johnson, James D Kubicki, F Omar Holguin, Barry Dungan, Kenneth C Carroll. Cyclodextrin-enhanced 1,4-dioxane treatment kinetics with TCE and 1,1,1-TCA using aqueous ozone. Chemosphere. 2019 Mar; 219(?):335-344. doi: 10.1016/j.chemosphere.2018.11.200. [PMID: 30551099]
  • Wei-Jing Chen, Bao-Cheng Zhao, Xue-Fei Cao, Tong-Qi Yuan, Quentin Shi, Shuang-Fei Wang, Run-Cang Sun. Structural Features of Alkaline Dioxane Lignin and Residual Lignin from Eucalyptus grandis × E. urophylla. Journal of agricultural and food chemistry. 2019 Jan; 67(3):968-974. doi: 10.1021/acs.jafc.8b05760. [PMID: 30580517]
  • Liang Qu, Satoshi Fudo, Katsumi Matsuzaki, Tyuji Hoshino. Computational Study on the Assembly of Amyloid β-Peptides in the Hydrophobic Environment. Chemical & pharmaceutical bulletin. 2019; 67(9):959-965. doi: 10.1248/cpb.c19-00171. [PMID: 31474736]
  • Kanji Niwa, Naonobu Tanaka, Sang-Yong Kim, Mareshige Kojoma, Yoshiki Kashiwada. Hyperdioxane A, a Conjugate of Dibenzo-1,4-dioxane and Sesquiterpene from Hypericum ascyron. Organic letters. 2018 09; 20(18):5977-5980. doi: 10.1021/acs.orglett.8b02739. [PMID: 30207481]
  • Justin Y C Lau, Benjamin J Geraghty, Albert P Chen, Charles H Cunningham. Improved tolerance to off-resonance in spectral-spatial EPI of hyperpolarized [1-13 C]pyruvate and metabolites. Magnetic resonance in medicine. 2018 09; 80(3):925-934. doi: 10.1002/mrm.27086. [PMID: 29380423]
  • Bao-Cheng Zhao, Ji-Dong Xu, Bo-Yang Chen, Xue-Fei Cao, Tong-Qi Yuan, Shuang-Fei Wang, Adam Charlton, Run-Cang Sun. Selective precipitation and characterization of lignin-carbohydrate complexes (LCCs) from Eucalyptus. Planta. 2018 May; 247(5):1077-1087. doi: 10.1007/s00425-018-2842-9. [PMID: 29350280]
  • Naima A Khan, Michael D Johnson, Kenneth C Carroll. Spectroscopic methods for aqueous cyclodextrin inclusion complex binding measurement for 1,4-dioxane, chlorinated co-contaminants, and ozone. Journal of contaminant hydrology. 2018 03; 210(?):31-41. doi: 10.1016/j.jconhyd.2018.02.002. [PMID: 29478672]
  • Ron Shah, Kaitlyn Margison, Derek A Pratt. The Potency of Diarylamine Radical-Trapping Antioxidants as Inhibitors of Ferroptosis Underscores the Role of Autoxidation in the Mechanism of Cell Death. ACS chemical biology. 2017 10; 12(10):2538-2545. doi: 10.1021/acschembio.7b00730. [PMID: 28837769]
  • Janos Balogh, Antsar Rih Hlil, Ibrahim El-Zoghbi, Muhammad Ghufran Rafique, Dalila Chouikhi, Mohammed Al-Hashimi, Hassan S Bazzi. Phase-Separable Polyisobutylene Palladium-PEPPSI Precatalysts: Synthesis and Application in Buchwald-Hartwig Amination. Macromolecular rapid communications. 2017 Aug; 38(15):. doi: 10.1002/marc.201700214. [PMID: 28627077]
  • Hiroki Suzuki, Tatsuru Moritani, Tadahiko Morinaga, Yoshiki Seto, Hideyuki Sato, Satomi Onoue. Amorphous solid dispersion of cyclosporine A prepared with fine droplet drying process: Physicochemical and pharmacokinetic characterization. International journal of pharmaceutics. 2017 Mar; 519(1-2):213-219. doi: 10.1016/j.ijpharm.2017.01.018. [PMID: 28093327]
  • Thomas Göen, Franziska von Helden, Elisabeth Eckert, Udo Knecht, Hans Drexler, Dirk Walter. Metabolism and toxicokinetics of 1,4-dioxane in humans after inhalational exposure at rest and under physical stress. Archives of toxicology. 2016 Jun; 90(6):1315-24. doi: 10.1007/s00204-015-1567-9. [PMID: 26223317]
  • Said Mnaa, Emad S Shaker, Hemdan I Mahmoud. INHIBITORY ACTIVITY OF PROTECTED EDIBLE PLANTS ON OXIDATIVE STRESS INDUCED BY ORAL 1,4-DIOXANE. Journal of the Egyptian Society of Parasitology. 2016 Apr; 46(1):135-43. doi: 10.12816/0026159. [PMID: 27363050]
  • Mei Sun, Catalina Lopez-Velandia, Detlef R U Knappe. Determination of 1,4-Dioxane in the Cape Fear River Watershed by Heated Purge-and-Trap Preconcentration and Gas Chromatography-Mass Spectrometry. Environmental science & technology. 2016 Mar; 50(5):2246-54. doi: 10.1021/acs.est.5b05875. [PMID: 26829406]
  • Jordi Quintana, Lídia Vegué, Jordi Martín-Alonso, Miquel Paraira, M Rosa Boleda, Francesc Ventura. Odor Events in Surface and Treated Water: The Case of 1,3-Dioxane Related Compounds. Environmental science & technology. 2016 Jan; 50(1):62-9. doi: 10.1021/acs.est.5b03409. [PMID: 26592899]
  • Jorge Rencoret, Pepijn Prinsen, Ana Gutiérrez, Ángel T Martínez, José C Del Río. Isolation and structural characterization of the milled wood lignin, dioxane lignin, and cellulolytic lignin preparations from brewer's spent grain. Journal of agricultural and food chemistry. 2015 Jan; 63(2):603-13. doi: 10.1021/jf505808c. [PMID: 25520237]
  • Osama K Abou-Zied, John Husband, Najla Al-Lawatia, Thomas B Steinbrecher. Ground state spectroscopy of hydroxyquinolines: evidence for the formation of protonated species in water-rich dioxane-water mixtures. Physical chemistry chemical physics : PCCP. 2014 Jan; 16(1):61-70. doi: 10.1039/c3cp52811a. [PMID: 24158492]
  • Nataša P Milošević, Srdjan Z Stojanović, Katarina Penov-Gaši, Nada Perišić-Janjić, Roman Kaliszan. Reversed- and normal-phase liquid chromatography in quantitative structure retention-property relationships of newly synthesized seco-androstene derivatives. Journal of pharmaceutical and biomedical analysis. 2014 Jan; 88(?):636-42. doi: 10.1016/j.jpba.2013.10.011. [PMID: 24216283]
  • Wirongrong Kaweetripob, Chulabhorn Mahidol, Hunsa Prawat, Somsak Ruchirawat. Lupane, friedelane, oleanane, and ursane triterpenes from the stem of Siphonodon celastrineus Griff. Phytochemistry. 2013 Dec; 96(?):404-17. doi: 10.1016/j.phytochem.2013.09.027. [PMID: 24156869]
  • Staci Massey Simonich, Ping Sun, Ken Casteel, Scott Dyer, Dave Wernery, Kevin Garber, Gregory Carr, Thomas Federle. Probabilistic analysis of risks to US drinking water intakes from 1,4-dioxane in domestic wastewater treatment plant effluents. Integrated environmental assessment and management. 2013 Oct; 9(4):554-9. doi: 10.1002/ieam.1448. [PMID: 23713009]
  • Elisabeth Eckert, Wolfgang Gries, Thomas Göen, Gabriele Leng. Reliable quantitation of β-hydroxyethoxyacetic acid in human urine by an isotope-dilution GC-MS procedure. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2013 Sep; 935(?):80-4. doi: 10.1016/j.jchromb.2013.07.017. [PMID: 23954659]
  • Tobias Leutritz, Liane Hilfert, Karl-Heinz Smalla, Oliver Speck, Kai Zhong. Accurate quantification of water-macromolecule exchange induced frequency shift: effects of reference substance. Magnetic resonance in medicine. 2013 Jan; 69(1):263-8. doi: 10.1002/mrm.24223. [PMID: 22374834]
  • Ari M Ferro, Jean Kennedy, James C LaRue. Phytoremediation of 1,4-dioxane-containing recovered groundwater. International journal of phytoremediation. 2013; 15(10):911-23. doi: 10.1080/15226514.2012.687018. [PMID: 23819285]
  • Jolanta Kamińnska, Joanna Sobiak, Maciej Głyda, Grażyna Duda, Małgorzata Nogala-Kałucka, Aleksander Siger, Maria Chrzanowska. Effect of clinical condition and mycophenolate mofetil on plasma retinol, α-tocopherol and β-carotene in renal transplant recipients. Archives of medical science : AMS. 2012 May; 8(2):256-62. doi: 10.5114/aoms.2012.28553. [PMID: 22661998]
  • Dinesh Singh Moirangthem, Narayan Chandra Talukdar, Naresh Kasoju, Utpal Bora. Antioxidant, antibacterial, cytotoxic, and apoptotic activity of stem bark extracts of Cephalotaxus griffithii Hook. f. BMC complementary and alternative medicine. 2012 Apr; 12(?):30. doi: 10.1186/1472-6882-12-30. [PMID: 22469333]
  • Yan Liu, Nina M Haste, Wdee Thienphrapa, Victor Nizet, Mary Hensler, Rongshi Li. Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (I). Marine drugs. 2012 Apr; 10(4):953-62. doi: 10.3390/md10040953. [PMID: 22690153]
  • Steven A Akman, Marissa Adams, Doug Case, Gyungse Park, Richard A Manderville. Mutagenicity of ochratoxin A and its hydroquinone metabolite in the SupF gene of the mutation reporter plasmid Ps189. Toxins. 2012 Apr; 4(4):267-80. doi: 10.3390/toxins4040267. [PMID: 22606376]
  • Pilar Galindo, Isabel Rodriguez-Gómez, Susana González-Manzano, Montserrat Dueñas, Rosario Jiménez, Carmen Menéndez, Félix Vargas, Juan Tamargo, Celestino Santos-Buelga, Francisco Pérez-Vizcaíno, Juan Duarte. Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation. PloS one. 2012; 7(3):e32673. doi: 10.1371/journal.pone.0032673. [PMID: 22427863]
  • Gabriela Ciapetti, Donatella Granchi, Valentina Devescovi, Serena R Baglio, Elisa Leonardi, Desirèe Martini, Maria Jesus Jurado, Beatriz Olalde, Ilaria Armentano, Josè M Kenny, Frank X Walboomers, Josè Inaki Alava, Nicola Baldini. Enhancing osteoconduction of PLLA-based nanocomposite scaffolds for bone regeneration using different biomimetic signals to MSCs. International journal of molecular sciences. 2012; 13(2):2439-58. doi: 10.3390/ijms13022439. [PMID: 22408463]
  • Elad Cohen, Michael Aviram, Soliman Khatib, Asaf Rabin, Dalit Mannheim, Ron Karmeli, Jacob Vaya. Increased Levels of Human Carotid Lesion Linoleic Acid Hydroperoxide in Symptomatic and Asymptomatic Patients Is Inversely Correlated with Serum HDL and Paraoxonase 1 Activity. Journal of lipids. 2012; 2012(?):762560. doi: 10.1155/2012/762560. [PMID: 22690338]
  • Laxminarain Misra, Priyanka Mishra, Archana Pandey, Rajender S Sangwan, Neelam S Sangwan. 1,4-Dioxane and ergosterol derivatives from Withania somnifera roots. Journal of Asian natural products research. 2012; 14(1):39-45. doi: 10.1080/10286020.2011.622719. [PMID: 22263592]
  • Xiao-Fei Tian, Zhen Fang, Dan Jiang, Xi-Yan Sun. Pretreatment of microcrystalline cellulose in organic electrolyte solutions for enzymatic hydrolysis. Biotechnology for biofuels. 2011 Nov; 4(1):53. doi: 10.1186/1754-6834-4-53. [PMID: 22099703]
  • Matthew W Meyer, Jason S Lupoi, Emily A Smith. 1064 nm dispersive multichannel Raman spectroscopy for the analysis of plant lignin. Analytica chimica acta. 2011 Nov; 706(1):164-70. doi: 10.1016/j.aca.2011.08.031. [PMID: 21995924]
  • Anup Gurung, Sedky H A Hassan, Sang-Eun Oh. Assessing acute toxicity of effluent from a textile industry and nearby river waters using sulfur-oxidizing bacteria in continuous mode. Environmental technology. 2011 Oct; 32(13-14):1597-604. doi: 10.1080/09593330.2010.545081. [PMID: 22329151]
  • Agnieszka Kosińska, Kamila Penkacik, Wiesław Wiczkowski, Ryszard Amarowicz. Presence of caffeic acid in flaxseed lignan macromolecule. Plant foods for human nutrition (Dordrecht, Netherlands). 2011 Sep; 66(3):270-4. doi: 10.1007/s11130-011-0245-1. [PMID: 21766213]
  • Minerva Martínez-Alfaro, Yolanda Alcaraz-Contreras, Alfonso Cárabez-Trejo, Guillermo E Leo-Amador. Oxidative stress effects of thinner inhalation. Indian journal of occupational and environmental medicine. 2011 Sep; 15(3):87-92. doi: 10.4103/0019-5278.93195. [PMID: 22412283]
  • Maureen R A Edwards, Marie-France Hetu, Melanie Columbus, Anthony Silva, Daniel D Lefebvre. The effect of ethylene glycol on the phytovolatilization of 1,4-dioxane. International journal of phytoremediation. 2011 Aug; 13(7):702-16. doi: 10.1080/15226514.2010.525553. [PMID: 21972497]
  • Alexandros B Tsoupras, Maria Chini, Nickolaos Tsogas, Athina Lioni, George Tsekes, Constantinos A Demopoulos, Marios C Lazanas. In vitro anti-inflammatory and anti-coagulant effects of antibiotics towards Platelet Activating Factor and thrombin. Journal of inflammation (London, England). 2011 Jul; 8(?):17. doi: 10.1186/1476-9255-8-17. [PMID: 21736752]
  • Chantana Aromdee, Supawadee Suebsasana, Tipaya Ekalaksananan, Chamsai Pientong, Sasithorn Thongchai. Stage of action of naturally occurring andrographolides and their semisynthetic analogues against herpes simplex virus type 1 in vitro. Planta medica. 2011 Jun; 77(9):915-21. doi: 10.1055/s-0030-1250659. [PMID: 21259187]
  • Monica A Schmidt, W Brad Barbazuk, Michael Sandford, Greg May, Zhihong Song, Wenxu Zhou, Basil J Nikolau, Eliot M Herman. Silencing of soybean seed storage proteins results in a rebalanced protein composition preserving seed protein content without major collateral changes in the metabolome and transcriptome. Plant physiology. 2011 May; 156(1):330-45. doi: 10.1104/pp.111.173807. [PMID: 21398260]
  • Romualdo S Fukushima, Monty S Kerley. Use of lignin extracted from different plant sources as standards in the spectrophotometric acetyl bromide lignin method. Journal of agricultural and food chemistry. 2011 Apr; 59(8):3505-9. doi: 10.1021/jf104826n. [PMID: 21375240]
  • Elena I Sinauridze, Alexey N Romanov, Irina V Gribkova, Olga A Kondakova, Stepan S Surov, Aleksander S Gorbatenko, Andrey A Butylin, Mikhail Yu Monakov, Alexey A Bogolyubov, Yuryi V Kuznetsov, Vladimir B Sulimov, Fazoyl I Ataullakhanov. New synthetic thrombin inhibitors: molecular design and experimental verification. PloS one. 2011; 6(5):e19969. doi: 10.1371/journal.pone.0019969. [PMID: 21603576]
  • Tobias Kohl, Eva Lörinczi, Luis A Pardo, Walter Stühmer. Rapid internalization of the oncogenic K+ channel K(V)10.1. PloS one. 2011; 6(10):e26329. doi: 10.1371/journal.pone.0026329. [PMID: 22022602]
  • Carla Cruz, Elisa Cairrao, Samuel Silvestre, Luiza Breitenfeld, Paulo Almeida, João A Queiroz. Targeting of mitochondria-endoplasmic reticulum by fluorescent macrocyclic compounds. PloS one. 2011; 6(11):e27078. doi: 10.1371/journal.pone.0027078. [PMID: 22132086]
  • Antonio Raudino, Maria Grazia Sarpietro, Martina Pannuzzo. The thermodynamics of simple biomembrane mimetic systems. Journal of pharmacy & bioallied sciences. 2011 Jan; 3(1):15-38. doi: 10.4103/0975-7406.76462. [PMID: 21430953]
  • Zhong-Cheng Song, Ying Guo, Wen-Hong Liu, Li-Chun Hu, Sheng-Nan Cai. (2R,4R)-3-(tert-But-oxy-carbon-yl)-2-(3-chloro-phen-yl)-1,3-thia-zolidine-4-carb-oxy-lic acid monohydrate. Acta crystallographica. Section E, Structure reports online. 2010 Oct; 66(Pt 11):o2934. doi: 10.1107/s1600536810042133. [PMID: 21589105]
  • Tania Vescovi, Heather M Coleman, Rose Amal. The effect of pH on UV-based advanced oxidation technologies--1,4-dioxane degradation. Journal of hazardous materials. 2010 Oct; 182(1-3):75-9. doi: 10.1016/j.jhazmat.2010.06.001. [PMID: 20598439]
  • Hossein Mazaheri, Keat Teong Lee, Subhash Bhatia, Abdul Rahman Mohamed. Sub/supercritical liquefaction of oil palm fruit press fiber for the production of bio-oil: effect of solvents. Bioresource technology. 2010 Oct; 101(19):7641-7. doi: 10.1016/j.biortech.2010.04.072. [PMID: 20510608]
  • Xiao-Feng Sun, Paul Fowler, Mohanathas Rajaratnam, Guangcheng Zhang. Extraction and characterisation of hemicelluloses from maize stem. Phytochemical analysis : PCA. 2010 Sep; 21(5):406-15. doi: 10.1002/pca.1211. [PMID: 20333614]
  • F Barclay Shilliday, Daniel P Walker, Chungang Gu, Xiaojun Fang, Bruce Thornburgh, Gwendolyn D Fate, J Scott Daniels. Multiple species metabolism of PHA-568487, a selective alpha 7 nicotinic acetylcholine receptor agonist. Drug metabolism letters. 2010 Aug; 4(3):162-72. doi: NULL. [PMID: 20642449]
  • Yvonne Nygren, Erik Björn. Mobile phase selection for the combined use of liquid chromatography-inductively coupled plasma mass spectrometry and electrospray ionisation mass spectrometry. Journal of chromatography. A. 2010 Jul; 1217(30):4980-6. doi: 10.1016/j.chroma.2010.05.062. [PMID: 20573350]
  • Víctor González-Ruiz, Pierluigi Mussardo, Elisa Corda, Stefano Girotti, Ana I Olives, María Antonia Martín. Liquid chromatographic analysis of the anticancer alkaloid luotonin A and some new derivatives in human serum samples. Journal of separation science. 2010 Jul; 33(14):2086-93. doi: 10.1002/jssc.201000175. [PMID: 20568252]
  • John H Grabber, Paul F Schatz, Hoon Kim, Fachuang Lu, John Ralph. Identifying new lignin bioengineering targets: 1. Monolignol-substitute impacts on lignin formation and cell wall fermentability. BMC plant biology. 2010 Jun; 10(?):114. doi: 10.1186/1471-2229-10-114. [PMID: 20565789]
  • Li-Ying Song, Wan-Xiang Lu, Jun Hu, Yan Zhang, Wei-Bo Yin, Yu-Hong Chen, Shan-Ting Hao, Bai-Lin Wang, Richard R-C Wang, Zan-Min Hu. Identification and functional analysis of the genes encoding Delta6-desaturase from Ribes nigrum. Journal of experimental botany. 2010 Jun; 61(6):1827-38. doi: 10.1093/jxb/erq051. [PMID: 20231328]
  • Giovanni Murtas. Internal lipid synthesis and vesicle growth as a step toward self-reproduction of the minimal cell. Systems and synthetic biology. 2010 Jun; 4(2):85-93. doi: 10.1007/s11693-009-9048-1. [PMID: 19957048]
  • Jin-Ok Choi, Mi Hee Lee, Hae-Young Park, Sung-Chul Jung. Characterization of Fabry mice treated with recombinant adeno-associated virus 2/8-mediated gene transfer. Journal of biomedical science. 2010 Apr; 17(?):26. doi: 10.1186/1423-0127-17-26. [PMID: 20398385]
  • Sheryl R Kane, Paul D Ashby, Lisa A Pruitt. Microscale wear behavior and crosslinking of PEG-like coatings for total hip replacements. Journal of materials science. Materials in medicine. 2010 Apr; 21(4):1037-45. doi: 10.1007/s10856-009-3935-6. [PMID: 20091104]
  • Cliff E Foster, Tina M Martin, Markus Pauly. Comprehensive compositional analysis of plant cell walls (Lignocellulosic biomass) part I: lignin. Journal of visualized experiments : JoVE. 2010 Mar; ?(37):. doi: 10.3791/1745. [PMID: 20224547]
  • Jing-Zheng Song, Quan-Bin Han, Chun-Feng Qiao, Paul Pui-Hay But, Hong-Xi Xu. Development and validation of a rapid capillary zone electrophoresis method for the determination of aconite alkaloids in aconite roots. Phytochemical analysis : PCA. 2010 Mar; 21(2):137-43. doi: 10.1002/pca.1168. [PMID: 19810124]
  • Jacek Achrem-Achremowicz, Elzbieta Kepczyńska, Marek Zylewski, Zbigniew Janeczko. Synthesis of betulin derivatives and the determination of their relative lipophilicities using reversed-phase thin-layer chromatography. Biomedical chromatography : BMC. 2010 Mar; 24(3):261-7. doi: 10.1002/bmc.1282. [PMID: 19591243]
  • F Schoonenberg Kegel, B M Rietman, A R D Verliefde. Reverse osmosis followed by activated carbon filtration for efficient removal of organic micropollutants from river bank filtrate. Water science and technology : a journal of the International Association on Water Pollution Research. 2010; 61(10):2603-10. doi: 10.2166/wst.2010.166. [PMID: 20453334]
  • Amal A Kinawy. Impact of gasoline inhalation on some neurobehavioural characteristics of male rats. BMC physiology. 2009 Nov; 9(?):21. doi: 10.1186/1472-6793-9-21. [PMID: 19930677]
  • Tanja Schaffran, Alexander Burghardt, Sabine Barnert, Regine Peschka-Süss, Rolf Schubert, Mathias Winterhalter, Detlef Gabel. Pyridinium lipids with the dodecaborate cluster as polar headgroup: synthesis, characterization of the physical-chemical behavior, and toxicity in cell culture. Bioconjugate chemistry. 2009 Nov; 20(11):2190-8. doi: 10.1021/bc900147w. [PMID: 19839599]
  • Yuanlong Wei, Tao Lan, Tao Tang, Lingyi Zhang, Fengyun Wang, Tong Li, Yiping Du, Weibing Zhang. A comprehensive two-dimensional normal-phase x reversed-phase liquid chromatography based on the modification of mobile phases. Journal of chromatography. A. 2009 Oct; 1216(44):7466-71. doi: 10.1016/j.chroma.2009.08.029. [PMID: 19712935]
  • Matthias Kinne, Marzena Poraj-Kobielska, Sally A Ralph, René Ullrich, Martin Hofrichter, Kenneth E Hammel. Oxidative cleavage of diverse ethers by an extracellular fungal peroxygenase. The Journal of biological chemistry. 2009 Oct; 284(43):29343-9. doi: 10.1074/jbc.m109.040857. [PMID: 19713216]
  • Phyllis S Frisa, James W Jacobberger. Cell cycle-related cyclin b1 quantification. PloS one. 2009 Sep; 4(9):e7064. doi: 10.1371/journal.pone.0007064. [PMID: 19763267]
  • Tatsuya Kasai, Hirokazu Kano, Yumi Umeda, Toshiaki Sasaki, Naoki Ikawa, Tomoshi Nishizawa, Kasuke Nagano, Heihachiro Arito, Hiroshi Nagashima, Shoji Fukushima. Two-year inhalation study of carcinogenicity and chronic toxicity of 1,4-dioxane in male rats. Inhalation toxicology. 2009 Sep; 21(11):889-97. doi: 10.1080/08958370802629610. [PMID: 19681729]
  • Kristin Skinner, Lynda Cuiffetti, Michael Hyman. Metabolism and cometabolism of cyclic ethers by a filamentous fungus, a Graphium sp. Applied and environmental microbiology. 2009 Sep; 75(17):5514-22. doi: 10.1128/aem.00078-09. [PMID: 19581469]
  • Hitoshi Ishida, Toshiyuki Wakimoto, Yukiko Kitao, Shimako Tanaka, Toshio Miyase, Haruo Nukaya. Quantitation of chafurosides A and B in tea leaves and isolation of prechafurosides A and B from oolong tea leaves. Journal of agricultural and food chemistry. 2009 Aug; 57(15):6779-86. doi: 10.1021/jf900032z. [PMID: 19572651]
  • Tatjana Djaković-Sekulić, Nada Perisić-Janjić, Evgenija Djurendi. Retention data from reverse-phase high-performance thin-layer chromatography in characterization of some bis-salicylic acid derivatives. Biomedical chromatography : BMC. 2009 Aug; 23(8):881-7. doi: 10.1002/bmc.1200. [PMID: 19360764]
  • Hideki Okada, Eri Fukushi, Akira Yamamori, Naoki Kawazoe, Shuichi Onodera, Jun Kawabata, Norio Shiomi. Structural analysis of three novel trisaccharides isolated from the fermented beverage of plant extracts. Chemistry Central journal. 2009 Jul; 3(?):8. doi: 10.1186/1752-153x-3-8. [PMID: 19604409]
  • Wendy Maury, Jason P Price, Melinda A Brindley, ChoonSeok Oh, Jeffrey D Neighbors, David F Wiemer, Nickolas Wills, Susan Carpenter, Cathy Hauck, Patricia Murphy, Mark P Widrlechner, Kathleen Delate, Ganesh Kumar, George A Kraus, Ludmila Rizshsky, Basil Nikolau. Identification of light-independent inhibition of human immunodeficiency virus-1 infection through bioguided fractionation of Hypericum perforatum. Virology journal. 2009 Jul; 6(?):101. doi: 10.1186/1743-422x-6-101. [PMID: 19594941]
  • Ari M Ferro, Carl E Tammi. Field note: irrigation of tree stands with groundwater containing 1,4-dioxane. International journal of phytoremediation. 2009 Jul; 11(5):425-40. doi: 10.1080/15226510802655914. [PMID: 19810346]
  • Zuzana Valnickova, Morten Thaysen-Andersen, Peter Højrup, Trine Christensen, Kristian W Sanggaard, Torsten Kristensen, Jan J Enghild. Biochemical characterization of bovine plasma thrombin-activatable fibrinolysis inhibitor (TAFI). BMC biochemistry. 2009 May; 10(?):13. doi: 10.1186/1471-2091-10-13. [PMID: 19416536]
  • Zhaoqiang Wu, Hong Chen, Xiaoli Liu, Yanxia Zhang, Dan Li, He Huang. Protein adsorption on poly(N-vinylpyrrolidone)-modified silicon surfaces prepared by surface-initiated atom transfer radical polymerization. Langmuir : the ACS journal of surfaces and colloids. 2009 Mar; 25(5):2900-6. doi: 10.1021/la8037523. [PMID: 19437703]
  • Zhan-Guo Gao, Bao Teng, Haitao Wu, Bhalchandra V Joshi, Gary L Griffiths, Kenneth A Jacobson. Synthesis and pharmacological characterization of [(125)I]MRS1898, a high-affinity, selective radioligand for the rat A(3) adenosine receptor. Purinergic signalling. 2009 Mar; 5(1):31-7. doi: 10.1007/s11302-008-9107-1. [PMID: 18528782]
  • Theodoros Symeonidis, Michael Chamilos, Dimitra J Hadjipavlou-Litina, Michael Kallitsakis, Konstantinos E Litinas. Synthesis of hydroxycoumarins and hydroxybenzo[f]- or [h]coumarins as lipid peroxidation inhibitors. Bioorganic & medicinal chemistry letters. 2009 Feb; 19(4):1139-42. doi: 10.1016/j.bmcl.2008.12.098. [PMID: 19150597]
  • Erik M Dettenmaier, William J Doucette, Bruce Bugbee. Chemical hydrophobicity and uptake by plant roots. Environmental science & technology. 2009 Jan; 43(2):324-9. doi: 10.1021/es801751x. [PMID: 19238959]
  • Ashraf M Mahmoud, Nasr Y Khalil, Ibrahim A Darwish, Tarek Aboul-Fadl. Selective Spectrophotometric and Spectrofluorometric Methods for the Determination of Amantadine Hydrochloride in Capsules and Plasma via Derivatization with 1,2-Naphthoquinone-4-sulphonate. International journal of analytical chemistry. 2009; 2009(?):810104. doi: 10.1155/2009/810104. [PMID: 20140080]
  • Rana Rais, Pablo M Gonzalez, Xiaowan Zheng, Stephen A Wring, James E Polli. Method to screen substrates of apical sodium-dependent bile acid transporter. The AAPS journal. 2008 Dec; 10(4):596-605. doi: 10.1208/s12248-008-9069-9. [PMID: 19085111]