LY382884 (BioDeep_00000009535)

   


代谢物信息卡片


(3S,4aR,6S,8aR)-6-[(4-carboxyphenyl)methyl]-decahydroisoquinoline-3-carboxylic acid

化学式: C18H23NO4 (317.1627)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CC2CNC(CC2CC1CC3=CC=C(C=C3)C(=O)O)C(=O)O
InChI: InChI=1S/C18H23NO4/c20-17(21)13-4-1-11(2-5-13)7-12-3-6-14-10-19-16(18(22)23)9-15(14)8-12/h1-2,4-5,12,14-16,19H,3,6-10H2,(H,20,21)(H,22,23)/t12-,14+,15-,16+/m1/s1



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 CA1, CA3, GRM5, ITPR3, POMC
Endoplasmic reticulum membrane 1 ITPR3
Nucleus 2 FOS, GRM1
cytosol 4 CA1, CA3, FOS, PRKCQ
dendrite 5 GRIK3, GRM1, GRM2, GRM5, OPRM1
nucleoplasm 4 FOS, GRIK2, GRIK5, ITPR3
RNA polymerase II transcription regulator complex 1 FOS
Cell membrane 13 GRID1, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRM1, GRM2, GRM3, GRM5, GRM8, OPRD1, OPRM1
Cell projection, axon 1 OPRM1
Multi-pass membrane protein 14 GRID1, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRM1, GRM2, GRM3, GRM5, GRM8, ITPR3, OPRD1, OPRM1
Synapse 3 CRH, GRM2, OPRM1
dendritic shaft 1 GRM5
glutamatergic synapse 7 GRID1, GRIK2, GRIK3, GRM1, GRM2, GRM3, GRM5
Golgi apparatus 1 OPRM1
neuronal cell body 2 GRM5, ITPR3
postsynapse 1 GRM5
presynaptic membrane 8 GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRM2, GRM3, OPRD1
endosome 1 OPRM1
plasma membrane 15 GRID1, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRM1, GRM2, GRM3, GRM5, GRM8, ITPR3, OPRD1, OPRM1, PRKCQ
synaptic vesicle membrane 1 OPRD1
terminal bouton 2 GRIK2, GRIK3
Membrane 11 GRIK2, GRIK3, GRIK4, GRIK5, GRM2, GRM3, GRM5, GRM8, ITPR3, OPRD1, OPRM1
axon 4 GRIK3, GRM2, GRM3, OPRM1
brush border 1 ITPR3
extracellular exosome 2 CA1, GRID1
endoplasmic reticulum 5 FOS, GRIK2, GRIK5, ITPR3, OPRM1
extracellular space 2 CRH, POMC
Schaffer collateral - CA1 synapse 2 GRM1, GRM5
intracellular membrane-bounded organelle 1 GRIK1
postsynaptic density 2 GRIK2, GRM3
Secreted 2 CRH, POMC
extracellular region 2 CRH, POMC
hippocampal mossy fiber to CA3 synapse 3 GRIK2, GRIK4, GRIK5
centriolar satellite 1 PRKCQ
varicosity 1 CRH
dendritic spine 2 GRM3, GRM5
neuronal dense core vesicle lumen 1 CRH
perikaryon 4 CRH, GRIK2, GRIK3, OPRM1
nucleolus 1 ITPR3
apical part of cell 1 ITPR3
postsynaptic membrane 7 GRID1, GRIK1, GRIK2, GRIK3, GRIK4, GRM2, GRM3
GABA-ergic synapse 1 GRID1
sarcoplasmic reticulum 1 ITPR3
secretory granule 1 POMC
nuclear outer membrane 1 ITPR3
Postsynaptic cell membrane 7 GRID1, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRM1
dendrite cytoplasm 2 GRIK2, GRIK3
kainate selective glutamate receptor complex 5 GRIK1, GRIK2, GRIK3, GRIK4, GRIK5
mossy fiber rosette 1 GRIK2
receptor complex 1 ITPR3
neuron projection 2 OPRD1, OPRM1
chromatin 1 FOS
cell projection 3 GRIK2, GRIK4, GRIK5
Cell projection, dendrite 2 GRM2, OPRM1
Presynaptic cell membrane 3 GRIK2, GRIK4, GRIK5
secretory granule lumen 1 POMC
secretory granule membrane 1 ITPR3
nuclear matrix 1 FOS
axon terminus 1 OPRD1
postsynaptic density membrane 9 GRID1, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRM1, GRM5, OPRD1
immunological synapse 1 PRKCQ
neuronal dense core vesicle 1 OPRD1
aggresome 1 PRKCQ
platelet dense tubular network membrane 1 ITPR3
protein-DNA complex 1 FOS
dendrite membrane 1 OPRD1
Cytoplasmic vesicle, secretory vesicle membrane 1 ITPR3
astrocyte projection 3 GRM2, GRM3, GRM5
transcription factor AP-1 complex 1 FOS
transport vesicle membrane 1 ITPR3
cytoplasmic side of endoplasmic reticulum membrane 1 ITPR3
[Isoform 12]: Cytoplasm 1 OPRM1
spine apparatus 1 OPRD1
G protein-coupled receptor dimeric complex 1 GRM1
G protein-coupled receptor homodimeric complex 1 GRM1


文献列表

  • Nathan K Evanson, Daniella C Van Hooren, James P Herman. GluR5-mediated glutamate signaling regulates hypothalamo-pituitary-adrenocortical stress responses at the paraventricular nucleus and median eminence. Psychoneuroendocrinology. 2009 Oct; 34(9):1370-9. doi: 10.1016/j.psyneuen.2009.04.011. [PMID: 19450932]
  • Andrew Alt, Brianne Weiss, Paul L Ornstein, Scott D Gleason, David Bleakman, Robert E Stratford, Jeffrey M Witkin. Anxiolytic-like effects through a GLUK5 kainate receptor mechanism. Neuropharmacology. 2007 Jun; 52(7):1482-7. doi: 10.1016/j.neuropharm.2007.02.005. [PMID: 17418283]
  • Jeppe K Christensen, Ana V Paternain, Sanja Selak, Philip K Ahring, Juan Lerma. A mosaic of functional kainate receptors in hippocampal interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2004 Oct; 24(41):8986-93. doi: 10.1523/jneurosci.2156-04.2004. [PMID: 15483117]