477-49-6 (BioDeep_00000860797)

Main id: BioDeep_00000000877

 

PANOMIX_OTCML-2023


代谢物信息卡片


(5aR,8aR,9R)-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydroisobenzofurano[5,6-f][1,3]benzodioxole-5,8-quinone

化学式: C22H20O8 (412.1158)
中文名称: 鬼臼脂毒酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(=O)C4=CC5=C(C=C24)OCO5
InChI: InChI=1S/C22H20O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-19H,8-9H2,1-3H3/t13-,18+,19-/m0/s1

描述信息

Podophyllotoxone is isolated from the roots of Dysosma versipellis and has anti-cancer activities.Podophyllotoxone is able to inhibit the tubulin polymerization[1].
Podophyllotoxone is isolated from the roots of Dysosma versipellis and has anti-cancer activities.Podophyllotoxone is able to inhibit the tubulin polymerization[1].

同义名列表

6 个代谢物同义名

(5aR,8aR,9R)-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydroisobenzofurano[5,6-f][1,3]benzodioxole-5,8-quinone; (5AR,8AR,9R)-9-(3,4,5-TRIMETHOXYPHENYL)-5A,6,8A,9-TETRAHYDROISOBENZOFURANO[5,6-F][1,3]BENZODIOXOLE-5,8-DIONE; Podophyllotoxone; 477-49-6; C10875; Podophyllotoxone



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

6 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 CDK2, EGFR, SOD1, STAT3, TUBB4B
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 1 EGFR
Nucleus 5 CDK2, EGFR, SOD1, STAT3, TUBB4B
cytosol 4 CDK2, SOD1, STAT3, TUBB4B
centrosome 1 CDK2
nucleoplasm 3 CDK2, SOD1, STAT3
RNA polymerase II transcription regulator complex 1 STAT3
Cell membrane 1 EGFR
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
cell junction 1 EGFR
cell surface 1 EGFR
glutamatergic synapse 1 EGFR
Golgi membrane 1 EGFR
neuronal cell body 1 SOD1
endosome 2 CDK2, EGFR
plasma membrane 2 EGFR, STAT3
Membrane 1 EGFR
apical plasma membrane 1 EGFR
basolateral plasma membrane 1 EGFR
extracellular exosome 3 SOD1, SOD2, TUBB4B
extracellular space 2 EGFR, SOD1
perinuclear region of cytoplasm 1 EGFR
mitochondrion 2 SOD1, SOD2
protein-containing complex 2 EGFR, SOD1
Single-pass type I membrane protein 1 EGFR
extracellular region 2 SOD1, TUBB4B
Mitochondrion matrix 1 SOD2
mitochondrial matrix 2 SOD1, SOD2
transcription regulator complex 2 CDK2, STAT3
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 CDK2
nuclear membrane 1 EGFR
Extracellular vesicle 1 TUBB4B
cytoplasmic vesicle 1 SOD1
microtubule cytoskeleton 1 TUBB4B
axon cytoplasm 1 SOD1
Membrane raft 1 EGFR
Cytoplasm, cytoskeleton 1 TUBB4B
focal adhesion 1 EGFR
microtubule 1 TUBB4B
mitochondrial nucleoid 1 SOD2
Peroxisome 1 SOD1
intracellular vesicle 1 EGFR
mitochondrial intermembrane space 1 SOD1
dendrite cytoplasm 1 SOD1
receptor complex 1 EGFR
chromatin 1 STAT3
mitotic spindle 1 TUBB4B
cytoskeleton 1 TUBB4B
chromosome, telomeric region 1 CDK2
intercellular bridge 1 TUBB4B
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
nuclear envelope 1 CDK2
axonemal microtubule 1 TUBB4B
basal plasma membrane 1 EGFR
synaptic membrane 1 EGFR
male germ cell nucleus 1 CDK2
azurophil granule lumen 1 TUBB4B
clathrin-coated endocytic vesicle membrane 1 EGFR
Cajal body 1 CDK2
condensed chromosome 1 CDK2
Nucleus, Cajal body 1 CDK2
X chromosome 1 CDK2
Y chromosome 1 CDK2
cyclin-dependent protein kinase holoenzyme complex 1 CDK2
cyclin E1-CDK2 complex 1 CDK2
cyclin E2-CDK2 complex 1 CDK2
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
cyclin A2-CDK2 complex 1 CDK2
cyclin A1-CDK2 complex 1 CDK2


文献列表