Tagitinin F (BioDeep_00000007457)

   

PANOMIX_OTCML-2023


代谢物信息卡片


Tagitinin F

化学式: C19H24O6 (348.1572804)
中文名称: 圆叶肿柄菊素 F
谱图信息: 最多检出来源 Astragalus membranaceus(otcml) 83.33%

分子结构信息

SMILES: C=C1C(=O)OC2=C(C)C3(O)C=CC(C)(CC(OC(=O)C(C)C)C1C2)O3
InChI: InChI=1S/C19H24O6/c1-10(2)16(20)24-14-9-18(5)6-7-19(22,25-18)11(3)8-13-15(14)12(4)17(21)23-13/h6-8,10,13-15,22H,4,9H2,1-3,5H3/b11-8-/t13-,14-,15+,18+,19-/m1/s1

描述信息

同义名列表

1 个代谢物同义名

Tagitinin F



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Trinh Thi Thuy, Nguyen Thi Thuy Linh, Ba Thi Cham, Nguyen Thi Hoang Anh, Tran Duc Quan, Nguyen Thanh Tam, Le Thi Hong Nhung, Do Thi Thao, Nguyen Phi Hung, Vu Dinh Hoang, Sabrina Adorisio, Domenico V Delfino. Sesquiterpenoids from Tithonia diversifolia (Hemsl.) A. Gray induce apoptosis and inhibit the cell cycle progression of acute myeloid leukemia cells. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2023 Jan; 78(1-2):65-72. doi: 10.1515/znc-2021-0154. [PMID: 36321958]
  • Ruiran Wei, Yueqin Zhao, Juan Wang, Xu Yang, Shunlin Li, Yinyuan Wang, Xingzhi Yang, Jimin Fei, Xiaojiang Hao, Yuhan Zhao, Liming Gui, Xiao Ding. Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells. International journal of biological sciences. 2021; 17(11):2703-2717. doi: 10.7150/ijbs.59404. [PMID: 34345202]
  • Lihua Zhao, Zhonghui Hu, Shunlin Li, Lizhen Zhang, Ping Yu, Jie Zhang, Xue Zheng, Siddiqur Rahman, Zhongkai Zhang. Tagitinin A from Tithonia diversifolia provides resistance to tomato spotted wilt orthotospovirus by inducing systemic resistance. Pesticide biochemistry and physiology. 2020 Oct; 169(?):104654. doi: 10.1016/j.pestbp.2020.104654. [PMID: 32828372]
  • Victor Hugo Catricala Fernandes, Natalie de Barros Viera, Luiza Beatriz Lima Zanini, Aline de Fátima Silva, Paula Pio de Oliveira Salem, Marisi Gomes Soares, Karen de Jesus Nicácio, Ana Claudia Chagas de Paula, Luciano Sindra Virtuoso, Tiago Branquinho Oliveira, Eliane de Oliveira Silva, Danielle Ferreira Dias, Daniela Aparecida Chagas-Paula. Fast and Efficient Method to Obtain Tagitinin F by Photocyclization of Tagitinin C. Photochemistry and photobiology. 2020 01; 96(1):14-20. doi: 10.1111/php.13148. [PMID: 31400235]
  • Stefania Sut, Stefano Dall'Acqua, Valeria Baldan, Stephane L Ngahang Kamte, Farahnaz Ranjbarian, Prosper C Biapa Nya, Sauro Vittori, Giovanni Benelli, Filippo Maggi, Loredana Cappellacci, Anders Hofer, Riccardo Petrelli. Identification of tagitinin C from Tithonia diversifolia as antitrypanosomal compound using bioactivity-guided fractionation. Fitoterapia. 2018 Jan; 124(?):145-151. doi: 10.1016/j.fitote.2017.11.002. [PMID: 29146170]
  • Lihua Zhao, Jiahong Dong, Zhonghui Hu, Shunlin Li, Xiaoxia Su, Jie Zhang, Yueyan Yin, Tao Xu, Zhongkai Zhang, Hairu Chen. Anti-TMV activity and functional mechanisms of two sesquiterpenoids isolated from Tithonia diversifolia. Pesticide biochemistry and physiology. 2017 Aug; 140(?):24-29. doi: 10.1016/j.pestbp.2017.05.009. [PMID: 28755690]
  • Masahiko Suzuki, Arihiro Iwasaki, Kiyotake Suenaga, Hisashi Kato-Noguchi. Phytotoxic property of the invasive plant Tithonia diversifolia and a phytotoxic substance. Acta biologica Hungarica. 2017 Jun; 68(2):187-195. doi: 10.1556/018.68.2017.2.6. [PMID: 28605983]
  • Maria A F M Miranda, Rosa M Varela, Ascension Torres, José M G Molinillo, Sonia C J Gualtieri, Francisco A Macías. Phytotoxins from Tithonia diversifolia. Journal of natural products. 2015 May; 78(5):1083-92. doi: 10.1021/acs.jnatprod.5b00040. [PMID: 25879678]
  • May-Hua Liao, Yuan-Nuan Tsai, Chi-Yu Yang, Chi-Long Juang, Ming-Yi Lee, Li-Hsueh Chang, Hsiao-Chuan Wen. Anti-human hepatoma Hep-G2 proliferative, apoptotic, and antimutagenic activity of tagitinin C from Tithonia diversifolia leaves. Journal of natural medicines. 2013 Jan; 67(1):98-106. doi: 10.1007/s11418-012-0652-0. [PMID: 22476654]
  • Bruno Alves Rocha, Mônica Tallarico Pupo, Gilmara Ausech Antonucci, Suely Vilela Sampaio, Raquel de Melo Alves Paiva, Suraia Said, Leonardo Gobbo-Neto, Fernando Batista Da Costa. Microbial transformation of the sesquiterpene lactone tagitinin C by the fungus Aspergillus terreus. Journal of industrial microbiology & biotechnology. 2012 Nov; 39(11):1719-24. doi: 10.1007/s10295-012-1165-2. [PMID: 22782617]
  • May-Hua Liao, Wen-Chieh Lin, Hsiao-Chuan Wen, Hsiao-Fung Pu. Tithonia diversifolia and its main active component tagitinin C induce survivin inhibition and G2/M arrest in human malignant glioblastoma cells. Fitoterapia. 2011 Apr; 82(3):331-41. doi: 10.1016/j.fitote.2010.11.002. [PMID: 21073931]
  • Ming-Yi Lee, May-Hua Liao, Yung-Nuan Tsai, Kong-Hwa Chiu, Hsiao-Chuan Wen. Identification and anti-human glioblastoma activity of tagitinin C from Tithonia diversifolia methanolic extract. Journal of agricultural and food chemistry. 2011 Mar; 59(6):2347-55. doi: 10.1021/jf105003n. [PMID: 21332189]
  • María Elena Sánchez-Mendoza, Adelfo Reyes-Ramírez, Leticia Cruz Antonio, Luis Martínez Jiménez, Juan Rodríguez-Silverio, Jesús Arrieta. Bioassay-guided isolation of an anti-ulcer compound, tagitinin C, from Tithonia diversifolia: role of nitric oxide, prostaglandins and sulfhydryls. Molecules (Basel, Switzerland). 2011 Jan; 16(1):665-74. doi: 10.3390/molecules16010665. [PMID: 21242945]
  • Eric Goffin, Antonio Proença da Cunha, Eric Ziemons, Monique Tits, Luc Angenot, Michel Frederich. Quantification of tagitinin C in Tithonia diversifolia by reversed-phase high-performance liquid chromatography. Phytochemical analysis : PCA. 2003 Nov; 14(6):378-80. doi: 10.1002/pca.732. [PMID: 14667065]
  • Eric Goffin, Eric Ziemons, Patrick De Mol, Maria do Céu de Madureira, Ana Paula Martins, Antonio Proença da Cunha, Geneviève Philippe, Monique Tits, Luc Angenot, Michel Frederich. In vitro antiplasmodial activity of Tithonia diversifolia and identification of its main active constituent: tagitinin C. Planta medica. 2002 Jun; 68(6):543-5. doi: 10.1055/s-2002-32552. [PMID: 12094301]
  • R Pal, D K Kulshreshtha, R P Rastogi. Antileukemic and other constituents of Tithonia tagitiflora Desf. Journal of pharmaceutical sciences. 1976 Jun; 65(6):918-20. doi: 10.1002/jps.2600650631. [PMID: 932981]