Convicine (BioDeep_00000000713)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


6-Amino-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pyrimidine-2,4(1H,3H)-dione

化学式: C10H15N3O8 (305.0859)
中文名称:
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 93.24%

分子结构信息

SMILES: C(C1C(C(C(C(O1)OC2=C(NC(=O)NC2=O)N)O)O)O)O
InChI: InChI=1S/C10H15N3O8/c11-7-6(8(18)13-10(19)12-7)21-9-5(17)4(16)3(15)2(1-14)20-9/h2-5,9,14-17H,1H2,(H4,11,12,13,18,19)

描述信息

Convicine is a glycoside.
Convicine is a natural product found in Vicia faba and Vicia narbonensis with data available.

同义名列表

15 个代谢物同义名

6-Amino-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pyrimidine-2,4(1H,3H)-dione; 6-amino-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-1H-pyrimidine-2,4-dione; 6-amino-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1H-pyrimidine-2,4-dione; 6-amino-2-hydroxy-5-(beta-d-glucopyranosyloxy)-4-pyrimidinone; 6-amino-5-(b-d-glucopyranosyloxy)-2,4(1h,3h)-pyrimidinedione; 4-Amino-2,6-dihydroxypyrimidin-5-yl hexopyranoside; 6-Amino-5-beta-D-glucopyranosyloxyuracil; UNII-6O6R2591X5; CONVICINE [MI]; 6O6R2591X5; Convicine; AC1Q6LTN; AC1L3ETZ; Hexose + C4H5N3O2; Convicine



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

15 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Kjell Sergeant, Simon Goertz, Salma Halime, Hanna Tietgen, Hanna Heidt, Martina Minestrini, Cédric Jacquard, Stephanie Zimmer, Jenny Renaut. Exploration of the Diversity of Vicine and Convicine Derivatives in Faba Bean (Vicia faba L.) Cultivars: Insights from LC-MS/MS Spectra. Molecules (Basel, Switzerland). 2024 Feb; 29(5):. doi: 10.3390/molecules29051065. [PMID: 38474577]
  • Fitsum Getachew, Albert Vandenberg, Judit Smits. A practical toxicity bioassay for vicine and convicine levels in faba bean (Vicia faba). Journal of the science of food and agriculture. 2018 Oct; 98(13):5105-5111. doi: 10.1002/jsfa.9049. [PMID: 29611201]
  • Randy W Purves, Hamid Khazaei, Albert Vandenberg. Toward a high-throughput method for determining vicine and convicine levels in faba bean seeds using flow injection analysis combined with tandem mass spectrometry. Food chemistry. 2018 Aug; 256(?):219-227. doi: 10.1016/j.foodchem.2018.02.104. [PMID: 29606441]
  • Randy W Purves, Hamid Khazaei, Albert Vandenberg. Quantification of vicine and convicine in faba bean seeds using hydrophilic interaction liquid chromatography. Food chemistry. 2018 Feb; 240(?):1137-1145. doi: 10.1016/j.foodchem.2017.08.040. [PMID: 28946235]
  • Carlo Giuseppe Rizzello, Ilario Losito, Laura Facchini, Kati Katina, Francesco Palmisano, Marco Gobbetti, Rossana Coda. Degradation of vicine, convicine and their aglycones during fermentation of faba bean flour. Scientific reports. 2016 08; 6(?):32452. doi: 10.1038/srep32452. [PMID: 27578427]
  • Ramesh Buyyarapu, Ramesh V Kantety, John Z Yu, Sukumar Saha, Govind C Sharma. Development of New Candidate Gene and EST-Based Molecular Markers for Gossypium Species. International journal of plant genomics. 2011; 2011(?):894598. doi: 10.1155/2011/894598. [PMID: 22315588]
  • Heather Ray, Fawzy Georges. A genomic approach to nutritional, pharmacological and genetic issues of faba bean (Vicia faba): prospects for genetic modifications. GM crops. 2010 Mar; 1(2):99-106. doi: 10.4161/gmcr.1.2.11891. [PMID: 21865878]
  • Zafer Bicakci. A hemolysis trigger in glucose-6-phosphate dehydrogenase enzyme deficiency. Vicia sativa (Vetch). Saudi medical journal. 2009 Feb; 30(2):292-4. doi: . [PMID: 19198723]
  • F Erle, F Ceylan, T Erdemir, C Toker. Preliminary results on evaluation of chickpea, Cicer arietinum, genotypes for resistance to the pulse beetle, Callosobruchus maculatus. Journal of insect science (Online). 2009; 9(?):1-7. doi: 10.1673/031.009.5801. [PMID: 20050777]
  • C Burbano, C Cuadrado, M Muzquiz, J I Cubero. Variation of favism-inducing factors (vicine, convicine and L-DOPA) during pod development in Vicia faba L. Plant foods for human nutrition (Dordrecht, Netherlands). 1995 Apr; 47(3):265-75. doi: 10.1007/bf01088335. [PMID: 7659704]
  • M S Arbid, M S Madhyastha, R R Marquardt, A A Frohlich. Effect of neomycin on the hydrolysis and toxicity of vicine and convicine in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 1993 Nov; 31(11):835-40. doi: 10.1016/0278-6915(93)90221-j. [PMID: 8258412]
  • N Vural, S Sardas. Biological activities of broad bean (Vicia faba L.) extracts cultivated in South Anatolia in favism sensitive subjects. Toxicology. 1984 May; 31(2):175-9. doi: 10.1016/0300-483x(84)90009-x. [PMID: 6740693]
  • A Sisini, A Spanu, P Arese. [Genetic improvement in Vicia faba and favism. I. Distribution and levels of presumably hemolytic metabolites]. Bollettino della Societa italiana di biologia sperimentale. 1981 Jul; 57(14):1496-502. doi: . [PMID: 7295413]