(KDO)2-lipid IVA (BioDeep_00000006033)
代谢物信息卡片
化学式: C84H154N2O37P2 (1844.9705174)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCC(CC(=O)NC1C(C(C(OC1OP(=O)(O)O)COC2C(C(C(C(O2)COC3(CC(C(C(O3)C(CO)O)O)OC4(CC(C(C(O4)C(CO)O)O)O)C(=O)O)C(=O)O)OP(=O)(O)O)OC(=O)CC(CCCCCCCCCCC)O)NC(=O)CC(CCCCCCCCCCC)O)O)OC(=O)CC(CCCCCCCCCCC)O)O
InChI: InChI=1S/C84H154N2O37P2/c1-5-9-13-17-21-25-29-33-37-41-55(89)45-65(96)85-69-77(117-67(98)47-57(91)43-39-35-31-27-23-19-15-11-7-3)73(102)63(115-80(69)123-125(110,111)112)53-113-79-70(86-66(97)46-56(90)42-38-34-30-26-22-18-14-10-6-2)78(118-68(99)48-58(92)44-40-36-32-28-24-20-16-12-8-4)76(122-124(107,108)109)64(116-79)54-114-83(81(103)104)50-62(72(101)75(120-83)61(95)52-88)119-84(82(105)106)49-59(93)71(100)74(121-84)60(94)51-87/h55-64,69-80,87-95,100-102H,5-54H2,1-4H3,(H,85,96)(H,86,97)(H,103,104)(H,105,106)(H2,107,108,109)(H2,110,111,112)/t55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,83-,84-/m1/s1
描述信息
Lipid IVA glycosylated with two 3-deoxy-D-manno-octulosonic acid (KDO) residues.
同义名列表
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:28526
- KEGG: C06025
- PubChem: 3083382
- PubChem: 5233651
- MetaCyc: KDO2-LIPID-IVA
- CAS: 143600-83-3
- PMhub: MS000018969
- MetaboLights: MTBLC28526
- PubChem: 8297
- LipidMAPS: LMSL02000003
- 3DMET: B05149
- NIKKAJI: J2.760.959G
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
1 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(1)
- KDO transfer to lipid IVA I:
(KDO)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate ⟶ α-KDO-(2->4)-α-KDO-(2->6)-lipid IVA + CMP + H+
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xiaoyuan Wang, Peter J Quinn, Aixin Yan. Kdo2 -lipid A: structural diversity and impact on immunopharmacology.
Biological reviews of the Cambridge Philosophical Society.
2015 May; 90(2):408-27. doi:
10.1111/brv.12114. [PMID: 24838025] - Giles C Shih, Charlene M Kahler, Russell W Carlson, M Mahbubur Rahman, David S Stephens. gmhX, a novel gene required for the incorporation of L-glycero-D-manno-heptose into lipooligosaccharide in Neisseria meningitidis.
Microbiology (Reading, England).
2001 Aug; 147(Pt 8):2367-2377. doi:
10.1099/00221287-147-8-2367. [PMID: 11496013] - S M Carty, K R Sreekumar, C R Raetz. Effect of cold shock on lipid A biosynthesis in Escherichia coli. Induction At 12 degrees C of an acyltransferase specific for palmitoleoyl-acyl carrier protein.
The Journal of biological chemistry.
1999 Apr; 274(14):9677-85. doi:
10.1074/jbc.274.14.9677. [PMID: 10092655] - J L Kadrmas, C R Raetz. Enzymatic synthesis of lipopolysaccharide in Escherichia coli. Purification and properties of heptosyltransferase i.
The Journal of biological chemistry.
1998 Jan; 273(5):2799-807. doi:
10.1074/jbc.273.5.2799. [PMID: 9446588] - T A Garrett, J L Kadrmas, C R Raetz. Identification of the gene encoding the Escherichia coli lipid A 4'-kinase. Facile phosphorylation of endotoxin analogs with recombinant LpxK.
The Journal of biological chemistry.
1997 Aug; 272(35):21855-64. doi:
10.1074/jbc.272.35.21855. [PMID: 9268317] - S Mohan, C R Raetz. Endotoxin biosynthesis in Pseudomonas aeruginosa: enzymatic incorporation of laurate before 3-deoxy-D-manno-octulosonate.
Journal of bacteriology.
1994 Nov; 176(22):6944-51. doi:
10.1128/jb.176.22.6944-6951.1994. [PMID: 7961456] - N P Price, T M Kelly, C R Raetz, R W Carlson. Biosynthesis of a structurally novel lipid A in Rhizobium leguminosarum: identification and characterization of six metabolic steps leading from UDP-GlcNAc to 3-deoxy-D-manno-2-octulosonic acid2-lipid IVA.
Journal of bacteriology.
1994 Aug; 176(15):4646-55. doi:
10.1128/jb.176.15.4646-4655.1994. [PMID: 8045896] - M Boll, J Radziejewska-Lebrecht, C Warth, D Krajewska-Pietrasik, H Mayer. 4-Amino-4-deoxy-L-arabinose in LPS of enterobacterial R-mutants and its possible role for their polymyxin reactivity.
FEMS immunology and medical microbiology.
1994 May; 8(4):329-41. doi:
10.1111/j.1574-695x.1994.tb00460.x. [PMID: 8061656] - . .
.
. doi:
. [PMID: 10531340]