Debromoaplysiatoxin (BioDeep_00000005732)

   

natural product Marine Natural Products Volatile Flavor Compounds


代谢物信息卡片


Aplysiatoxin, 17-debromo-

化学式: C32H48O10 (592.3247308)
中文名称:
谱图信息: 最多检出来源 Mentha canadensis(plant) 96.88%

分子结构信息

SMILES: CC1CC(C23CC(C(C(O2)C(C)CCC(C4=CC(=CC=C4)O)OC)C)OC(=O)CC(OC(=O)CC1(O3)O)C(C)O)(C)C
InChI: InChI=1S/C32H48O10/c1-18(11-12-24(38-7)22-9-8-10-23(34)13-22)29-20(3)26-16-32(41-29)30(5,6)15-19(2)31(37,42-32)17-28(36)39-25(21(4)33)14-27(35)40-26/h8-10,13,18-21,24-26,29,33-34,37H,11-12,14-17H2,1-7H3/t18-,19+,20-,21+,24-,25+,26?,29+,31-,32-/m0/s1

描述信息

A member of the class of aplysiatoxins that has the structure of the parent aplysiatoxin, but is lacking the bromo substituent on the benzene ring at the position para to the phenolic hydroxy group. It is a cyanotoxin produced by several species of freshwater and marine cyanobacteria, as well as algae and molluscs.
D009676 - Noxae > D011042 - Poisons > D008235 - Lyngbya Toxins
D009676 - Noxae > D011042 - Poisons > D008387 - Marine Toxins
D009676 - Noxae > D002273 - Carcinogens

同义名列表

4 个代谢物同义名

Debromoaplysiatoxin; Aplysiatoxin, 17-debromo-; CID 440576; Debromoaplysiatoxin



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

44 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Sicheng Shen, Weiping Wang, Zijun Chen, Huihui Zhang, Yuchun Yang, Xiaoliang Wang, Peng Fu, Bingnan Han. Absolute Structure Determination and Kv1.5 Ion Channel Inhibition Activities of New Debromoaplysiatoxin Analogues. Marine drugs. 2021 Nov; 19(11):. doi: 10.3390/md19110630. [PMID: 34822501]
  • Angela Capper, Ian R Tibbetts, Judith M O'Neil, Glendon R Shaw. The fate of Lyngbya majuscula toxins in three potential consumers. Journal of chemical ecology. 2005 Jul; 31(7):1595-606. doi: 10.1007/s10886-005-5800-5. [PMID: 16222795]
  • K L Marshall, R L Vogt. Illness associated with eating seaweed, Hawaii, 1994. The Western journal of medicine. 1998 Nov; 169(5):293-5. doi: ". [PMID: 9830364]
  • H Ueyama, I Sasaki, K Shimomura, M Suganuma. Specific protein interacting with a tumor promoter, debromoaplysiatoxin, in bovine serum is alpha 1-acid glycoprotein. Journal of cancer research and clinical oncology. 1995; 121(4):211-8. doi: 10.1007/bf01366964. [PMID: 7751319]
  • A D Horowitz, H Fujiki, I B Weinstein, A Jeffrey, E Okin, R E Moore, T Sugimura. Comparative effects of aplysiatoxin, debromoaplysiatoxin, and teleocidin on receptor binding and phospholipid metabolism. Cancer research. 1983 Apr; 43(4):1529-35. doi: . [PMID: 6299522]
  • M K Samson, R L Stephens, S Rivkin, M Opipari, T Maloney, C W Groppe, R Fisher. Vinblastine, bleomycin, and cis-dichlorodiammineplatinum(II) in disseminated testicular cancer: preliminary report of a Southwest Oncology Group Study. Cancer treatment reports. 1979 Sep; 63(9-10):1663-7. doi: . [PMID: 91435]