tolbutamide (BioDeep_00000408956)
Main id: BioDeep_00000001520
代谢物信息卡片
tolbutamide
化学式: C12H18N2O3S (270.1038078)
中文名称: 甲苯磺丁脲
谱图信息:
最多检出来源 Homo sapiens(blood) 0.84%
分子结构信息
SMILES: CCCCNC(=O)NS(=O)(=O)c(c1)ccc(C)c1
InChI: InChI=1S/C12H18N2O3S/c1-3-4-9-13-12(15)14-18(16,17)11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3,(H2,13,14,15)
描述信息
A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BB - Sulfonylureas
C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C97936 - Sulfonylurea Antidiabetic Agent
V - Various > V04 - Diagnostic agents > V04C - Other diagnostic agents > V04CA - Tests for diabetes
An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
D007004 - Hypoglycemic Agents
同义名列表
1 个代谢物同义名
数据库引用编号
31 个数据库交叉引用编号
- ChEBI: CHEBI:27999
- KEGG: C07148
- KEGGdrug: D00380
- KEGGdrug: D87667
- PubChem: 5505
- DrugBank: DB01124
- ChEMBL: CHEMBL782
- MeSH: Tolbutamide
- CAS: 64-77-7
- MoNA: MoNA038841
- MoNA: MoNA038345
- MoNA: MoNA037600
- MoNA: MoNA036820
- MoNA: MoNA036818
- MoNA: MoNA036817
- MoNA: MoNA035495
- MoNA: MoNA035493
- MoNA: MoNA035492
- MoNA: MoNA033340
- MoNA: MoNA033339
- MoNA: MoNA033336
- MoNA: WA002506
- MoNA: WA002505
- MoNA: WA002504
- MoNA: WA002503
- MoNA: WA002502
- MoNA: WA002501
- MetaboLights: MTBLC27999
- PubChem: 9357
- NIKKAJI: J1.406K
- RefMet: Tolbutamide
分类词条
相关代谢途径
Reactome(5)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Hui-Lin Yang, Ying Li, Yi Chen, Si-Ying Chen, Yue-Ting Li, Yong Huang, Lin Zheng, Jing Huang, Yong-Lin Wang, Zi-Peng Gong. [Effect of Laportea bulbifera extract on CYP450 enzyme activities in rats by Cocktail probe drug method].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2022 Jul; 102(?):154203. doi:
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2022 07; 395(7):815-826. doi:
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Xenobiotica; the fate of foreign compounds in biological systems.
2021 May; 51(5):582-589. doi:
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Biopharmaceutics & drug disposition.
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Diabetologia.
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Brain research.
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Die Pharmazie.
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The AAPS journal.
2014 Mar; 16(2):258-68. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
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Journal of ethnopharmacology.
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Drug development and industrial pharmacy.
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Drug metabolism and pharmacokinetics.
2014; 29(2):154-61. doi:
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Pakistan journal of pharmaceutical sciences.
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Toxicological sciences : an official journal of the Society of Toxicology.
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European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
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2013; 36(10):1627-33. doi:
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Journal of animal science.
2013 Jan; 91(1):104-10. doi:
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Journal of chromatographic science.
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Drug metabolism and disposition: the biological fate of chemicals.
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Toxicology.
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
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