Cyazofamid (BioDeep_00000003971)

   

natural product


代谢物信息卡片


Pesticide5_Cyazofamid_C13H13ClN4O2S_4-Chloro-1-(dimethylaminosulfonyl)-5-(p-tolyl)imidazole-2-carbonitrile

化学式: C13H13ClN4O2S (324.0448)
中文名称: 氰唑胺
谱图信息: 最多检出来源 Escherichia coli(natural_products) 23.17%

分子结构信息

SMILES: Cc(c2)ccc(c2)c(c(Cl)1)n(c(C#N)n1)S(=O)(=O)N(C)C
InChI: InChI=1S/C13H13ClN4O2S/c1-9-4-6-10(7-5-9)12-13(14)16-11(8-15)18(12)21(19,20)17(2)3/h4-7H,1-3H3



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 1 OSBP
Peripheral membrane protein 1 OSBP
Endoplasmic reticulum membrane 1 OSBP
Mitochondrion membrane 1 SLC22A3
cytosol 1 OSBP
mitochondrial membrane 1 SLC22A3
trans-Golgi network 1 OSBP
nucleoplasm 1 OSBP
Cell membrane 4 KCNE1, SLC22A3, SLCO1B1, SLCO1B3
Multi-pass membrane protein 7 MT-CYB, SLC22A3, SLC22A6, SLC22A8, SLCO1B1, SLCO1B3, SYP
cell junction 1 OSBP
cell surface 1 KCNE1
Golgi apparatus 1 OSBP
Golgi membrane 1 OSBP
mitochondrial inner membrane 1 MT-CYB
neuromuscular junction 1 SYP
neuronal cell body 1 SLC22A3
presynaptic membrane 1 SYP
synaptic vesicle 1 SYP
Cytoplasm, cytosol 1 OSBP
Lysosome 1 KCNE1
Presynapse 1 SLC22A3
plasma membrane 7 KCNE1, OSBP, SLC22A3, SLC22A6, SLC22A8, SLCO1B1, SLCO1B3
presynaptic active zone 1 SYP
synaptic vesicle membrane 1 SYP
terminal bouton 1 SYP
Membrane 7 MT-CYB, OSBP, SLC22A3, SLC22A6, SLCO1B1, SLCO1B3, SYP
apical plasma membrane 3 KCNE1, SLC22A3, SLC22A8
basolateral plasma membrane 5 SLC22A3, SLC22A6, SLC22A8, SLCO1B1, SLCO1B3
caveola 1 SLC22A6
extracellular exosome 3 SERPING1, SLC22A6, SLC22A8
extracellular space 1 SERPING1
perinuclear region of cytoplasm 2 OSBP, SYP
Schaffer collateral - CA1 synapse 1 SYP
mitochondrion 1 MT-CYB
protein-containing complex 1 SLC22A6
Single-pass type I membrane protein 1 KCNE1
extracellular region 1 SERPING1
excitatory synapse 1 SYP
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 SYP
Nucleus membrane 1 SLC22A3
Z disc 1 KCNE1
nucleolus 1 OSBP
Apical cell membrane 2 KCNE1, SLC22A3
Cytoplasm, perinuclear region 1 OSBP
Mitochondrion inner membrane 1 MT-CYB
Membrane raft 1 KCNE1
collagen-containing extracellular matrix 1 SERPING1
lateral plasma membrane 1 SLC22A8
Nucleus outer membrane 1 SLC22A3
nuclear outer membrane 1 SLC22A3
neuron projection 1 SYP
Golgi apparatus, trans-Golgi network 1 OSBP
blood microparticle 1 SERPING1
Basolateral cell membrane 5 SLC22A3, SLC22A6, SLC22A8, SLCO1B1, SLCO1B3
Endomembrane system 2 SLC22A3, SYP
basal plasma membrane 4 SLC22A3, SLC22A6, SLCO1B1, SLCO1B3
voltage-gated potassium channel complex 1 KCNE1
endoplasmic reticulum lumen 1 SERPING1
platelet alpha granule lumen 1 SERPING1
perinuclear endoplasmic reticulum 1 OSBP
respiratory chain complex III 1 MT-CYB
Synapse, synaptosome 1 SYP
Basal cell membrane 3 SLC22A6, SLCO1B1, SLCO1B3


文献列表

  • Xuheng Gao, Wenhao Li, Shuai Wang, Bowen Xie, Qin Peng, Can Zhang, Jianqiang Miao, Tan Dai, Xili Liu. Attributes of Cyazofamid-Resistant Phytophthora litchii Mutants and Its Impact on Quality of Litchi Fruits. Journal of agricultural and food chemistry. 2024 Jan; 72(1):219-229. doi: 10.1021/acs.jafc.3c07325. [PMID: 38131297]
  • Hanna Yolanda, Kedchin Jearawuttanakul, Warawuth Wannalo, Phongthon Kanjanasirirat, Suparerk Borwornpinyo, Thidarat Rujirawat, Penpan Payattikul, Weerayuth Kittichotirat, Duangdao Wichadakul, Theerapong Krajaejun. Potential anti-Pythium insidiosum therapeutics identified through screening of agricultural fungicides. Microbiology spectrum. 2024 Jan; ?(?):e0162023. doi: 10.1128/spectrum.01620-23. [PMID: 38179943]
  • Semcheddine Cherrad, Benjamin Gillet, Julien Dellinger, Lalie Bellaton, Pascale Roux, Catalina Hernandez, Hervé Steva, Lauriane Perrier, Sébastien Vacher, Sandrine Hughes. New insights from short and long reads sequencing to explore cytochrome b variants in Plasmopara viticola populations collected from vineyards and related to resistance to complex III inhibitors. PloS one. 2023; 18(1):e0268385. doi: 10.1371/journal.pone.0268385. [PMID: 36656908]
  • Timothy B Siegenthaler, Zachariah R Hansen. Sensitivity of Phytophthora capsici from Tennessee to Mefenoxam, Fluopicolide, Oxathiapiprolin, Dimethomorph, Mandipropamid, and Cyazofamid. Plant disease. 2021 Oct; 105(10):3000-3007. doi: 10.1094/pdis-08-20-1805-re. [PMID: 33736467]
  • Im-Sook Song, Hyeon-Uk Jeong, Min-Koo Choi, Mihwa Kwon, Yongho Shin, Jeong Han Kim, Hye-Suk Lee. Interactions between cyazofamid and human drug transporters. Journal of biochemical and molecular toxicology. 2020 Apr; 34(4):e22459. doi: 10.1002/jbt.22459. [PMID: 32003934]
  • Qingxi Yang, Shiwei Wei, Na Liu, Zumin Gu. The Dissipation of Cyazofamid and Its Main Metabolite CCIM During Wine-Making Process. Molecules (Basel, Switzerland). 2020 Feb; 25(4):. doi: 10.3390/molecules25040777. [PMID: 32054034]
  • Qingxi Yang, Na Liu, Shuang Zhang, Weijing Wang, Yize Zou, Zumin Gu. The dissipation of cyazofamid and its main metabolite CCIM during tomato growth and tomato paste making process. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2019 Sep; 36(9):1327-1336. doi: 10.1080/19440049.2019.1626999. [PMID: 31226007]
  • Sizhuo Wu, Weiwei Yu, Caiyuan Sun, Kunming Zheng, Haizhen Zhang, Min Huang, Deyu Hu, Kankan Zhang. Simultaneous determination of residues of metalaxyl, cyazofamid and a cyazofamid metabolite in tobacco leaves and soil by liquid chromatography with tandem mass spectrometry. Biomedical chromatography : BMC. 2018 Apr; 32(4):. doi: 10.1002/bmc.4161. [PMID: 29226978]
  • Aiying Guan, Mingan Wang, Jinlong Yang, Lizeng Wang, Yong Xie, Jie Lan, Changling Liu. Discovery of a New Fungicide Candidate through Lead Optimization of Pyrimidinamine Derivatives and Its Activity against Cucumber Downy Mildew. Journal of agricultural and food chemistry. 2017 Dec; 65(49):10829-10835. doi: 10.1021/acs.jafc.7b03898. [PMID: 29151354]
  • Angela Fanigliulo, Vittorio Filì, Aniello Crescenzi. Cyazofamide: a fungicide against Bremia lactucae on lettuce. Communications in agricultural and applied biological sciences. 2009; 74(3):917-9. doi: . [PMID: 20222579]
  • Sudisha Jogaiah, Shigeru Mitani, Amruthesh Kestur Nagaraj, Shetty Huntrike Shekar. Activity of cyazofamid against Sclerospora graminicola, a downy mildew disease of pearl millet. Pest management science. 2007 Jul; 63(7):722-7. doi: 10.1002/ps.1383. [PMID: 17497752]
  • Shigeru Mitani, Koji Sugimoto, Hiroyuki Hayashi, Yasuko Takii, Takeshi Ohshima, Norifusa Matsuo. Effects of cyazofamid against Plasmodiophora brassicae Woronin on Chinese cabbage. Pest management science. 2003 Mar; 59(3):287-93. doi: 10.1002/ps.627. [PMID: 12639045]