Glutamylglutamic acid (BioDeep_00000003387)

 

Secondary id: BioDeep_00001869162

human metabolite Endogenous


代谢物信息卡片


(2S)-2-[(2S)-2-amino-4-carboxybutanamido]pentanedioic acid

化学式: C10H16N2O7 (276.0957466)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 6.94%

分子结构信息

SMILES: C(CC(=O)O)C(C(=O)NC(CCC(=O)O)C(=O)O)N
InChI: InChI=1S/C10H16N2O7/c11-5(1-3-7(13)14)9(17)12-6(10(18)19)2-4-8(15)16/h5-6H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)

描述信息

Glutamylglutamic acid is a dipeptide composed of two glutamic acid residues, and is a proteolytic breakdown product of larger proteins. It belongs to the family of N-acyl-alpha amino acids and derivatives. These are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. Glutamylglutamic acid is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis.
KEIO_ID G043; [MS2] KO008970
KEIO_ID G043

同义名列表

63 个代谢物同义名

(2S)-2-[(2S)-2-amino-4-carboxybutanamido]pentanedioic acid; Glutamic acid glutamic acid dipeptide; Glutamic acid-glutamic acid dipeptide; N-alpha-L-Glutamyl-L-glutamic acid; N-L-alpha-Glutamyl-L-glutamic acid; Glutamate glutamic acid dipeptide; Glutamic acid-glutamate dipeptide; Glutamate-glutamic acid dipeptide; Glutamic acid glutamate dipeptide; alpha-L-Glutamyl-L-glutamic acid; L-alpha-Glutamyl-L-glutamic acid; N-L-alpha-Glutamylglutamic acid; N-L-alpha-Glutamyl-L-glutamate; N-L-Α-glutamyl-L-glutamic acid; N-alpha-L-Glutamyl-L-glutamate; N-Α-L-glutamyl-L-glutamic acid; Dipotassium glutamyl-glutamate; Glutamate glutamate dipeptide; Glutamate-glutamate dipeptide; N-alpha-Glutamylglutamic acid; L-a-Glutamyl-L-glutamic acid; L-alpha-Glutamyl-L-glutamate; alpha-L-Glutamyl-L-glutamate; L-Α-glutamyl-L-glutamic acid; N-L-Glutamyl-L-glutamic acid; Α-L-glutamyl-L-glutamic acid; N-L-Α-glutamylglutamic acid; N-L-alpha-Glutamylglutamate; alpha-Glutamylglutamic acid; N-Α-L-glutamyl-L-glutamate; N-L-Α-glutamyl-L-glutamate; L-Glutamyl-L-glutamic acid; N-Α-glutamylglutamic acid; N-alpha-Glutamylglutamate; N-L-Glutamyl-L-glutamate; Α-L-glutamyl-L-glutamate; L-Α-glutamyl-L-glutamate; L-a-Glutamyl-L-glutamate; Α-glutamylglutamic acid; N-Glutamylglutamic acid; alpha-Glutamylglutamate; N-L-Α-glutamylglutamate; Glutamyl-glutamic acid; L-Glutamyl-L-glutamate; N-Α-glutamylglutamate; Glutamylglutamic acid; N-Glutamylglutamate; Α-glutamylglutamate; Glutamyl-glutamate; alpha-L-Glu-L-glu; Glutamylglutamate; H-L-Glu-L-glu-OH; Α-L-glu-L-glu; e-e Dipeptide; alpha-Glu-glu; H-Glu-glu-OH; EE dipeptide; L-Glu-L-glu; NSC 335983; Α-glu-glu; Glu-Glu; E-E; EE



数据库引用编号

28 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

6 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

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  • Benjamin W J Harper, Aviva Friedman-Ezra, Roman Sirota, Emanuele Petruzzella, Janice R Aldrich-Wright, Dan Gibson. Probing the Interactions of Cytotoxic [Pt(1S,2S-DACH)(5,6-dimethyl-1,10-phenanthroline)] and Its PtIV Derivatives with Human Serum. ChemMedChem. 2017 04; 12(7):510-519. doi: 10.1002/cmdc.201700092. [PMID: 28206707]
  • Mehvash Zaki, Mohd Afzal, Musheer Ahmad, Sartaj Tabassum. Synthesis and crystal structure elucidation of new copper(II)-based chemotherapeutic agent coupled with 1,2-DACH and orthovanillin: Validated by in vitro DNA/HSA binding profile and pBR322 cleavage pathway. Journal of photochemistry and photobiology. B, Biology. 2016 Aug; 161(?):318-27. doi: 10.1016/j.jphotobiol.2016.05.030. [PMID: 27289445]
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  • Yue-Yue Wang, Yu-Dong Li, Jian-Bo Liu, Xin-Xin Ran, Yuan-Yang Guo, Ni-Ni Ren, Xin Chen, Hui Jiang, Yong-Quan Li. Characterization and evolutionary implications of the triad Asp-Xxx-Glu in group II phosphopantetheinyl transferases. PloS one. 2014; 9(7):e103031. doi: 10.1371/journal.pone.0103031. [PMID: 25036863]
  • Amina Bouslimani, Nicole Bec, Matthias Glueckmann, Christophe Hirtz, Christian Larroque. Matrix-assisted laser desorption/ionization imaging mass spectrometry of oxaliplatin derivatives in heated intraoperative chemotherapy (HIPEC)-like treated rat kidney. Rapid communications in mass spectrometry : RCM. 2010 Feb; 24(4):415-21. doi: 10.1002/rcm.4408. [PMID: 20082287]
  • Griet Van Zeebroeck, Beatriz Monge Bonini, Matthias Versele, Johan M Thevelein. Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor. Nature chemical biology. 2009 Jan; 5(1):45-52. doi: 10.1038/nchembio.132. [PMID: 19060912]
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  • Ali Ouadi, Anthony Loussouarn, Laurence Morandeau, Patricia Remaud, Alain Faivre-Chauvet, John Webb, Jean-Francois Gestin. Influence of trans-1,2-diaminocyclohexane structure and mixed carboxylic/phosphonic group combinations on samarium-153 chelation capacity and stability. European journal of medicinal chemistry. 2004 May; 39(5):467-72. doi: 10.1016/j.ejmech.2004.02.009. [PMID: 15110973]
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