Tryptophanamide (BioDeep_00000003188)

 

Secondary id: BioDeep_00000412670

human metabolite Endogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


Tryptophanamide monohydrochloride, (S)-isomer

化学式: C11H13N3O (203.1059)
中文名称: 2-氨基-3-(1H-吲哚-3-基)-丙酰胺, 色氨酰胺
谱图信息: 最多检出来源 Homo sapiens(otcml) 10.51%

分子结构信息

SMILES: C1=CC=C2C(=C1)C(=CN2)CC(C(=O)N)N
InChI: InChI=1S/C11H13N3O/c12-9(11(13)15)5-7-6-14-10-4-2-1-3-8(7)10/h1-4,6,9,14H,5,12H2,(H2,13,15)

描述信息

Tryptophanamide is a substrate for tryptophan aminopeptidase (EC: 3.5.1.57)and is converted to L-Tryptophan via enzymatic hydrolysis. [HMDB]
Tryptophanamide is a substrate for tryptophan aminopeptidase (EC: 3.5.1.57)and is converted to L-Tryptophan via enzymatic hydrolysis.
KEIO_ID T054; [MS3] KO009291
KEIO_ID T054; [MS2] KO009290
KEIO_ID T054

同义名列表

14 个代谢物同义名

Tryptophanamide monohydrochloride, (S)-isomer; (S)-alpha-amino-1H-Indole-3-propionamide; alpha-amino-(S)-1H-Indole-3-propanamide; 2-Amino-3-(1H-indol-3-yl)propanimidate; 2-Amino-3-(1H-indol-3-yl)propanamide; alpha-amino-1H-Indole-3-propanamide; 2-amino-3-(3-Indolyl)-propanamide; Tryptophanamide, (+-)-isomer; Tryptophanamide, (S)-isomer; L-Tryptophanamide; tryptophan amide; Tryptophanamide; Tryptophanamide; L-Tryptophanamide



数据库引用编号

34 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 AFP, CDKN2A, CYP3A4, PGR, STAT6, WARS1
Peripheral membrane protein 2 CYP1B1, OSBP2
Endoplasmic reticulum membrane 3 CYP1A2, CYP1B1, CYP3A4
Nucleus 4 CDKN2A, PGR, STAT6, WARS1
cytosol 8 CDKN2A, CTSH, HTRA1, OSBP2, PGR, SST, STAT6, WARS1
nucleoplasm 4 ATP2B1, CDKN2A, PGR, STAT6
RNA polymerase II transcription regulator complex 1 STAT6
Cell membrane 2 ATP2B1, HTRA1
Multi-pass membrane protein 1 ATP2B1
Synapse 1 ATP2B1
glutamatergic synapse 1 ATP2B1
neuronal cell body 1 SST
presynaptic membrane 1 ATP2B1
Cytoplasm, cytosol 1 HTRA1
Lysosome 1 CTSH
acrosomal vesicle 1 OSBP2
plasma membrane 5 ATP2B1, BCHE, HTRA1, OSBP2, PGR
synaptic vesicle membrane 1 ATP2B1
Membrane 4 ATP2B1, CYP1B1, CYP3A4, OSBP2
axon 1 CCK
basolateral plasma membrane 1 ATP2B1
extracellular exosome 4 ATP2B1, CTSH, HTRA1, WARS1
extracellular space 8 AFP, BCHE, CCK, CTSH, GAST, GH1, HTRA1, SST
mitochondrion 2 CDKN2A, CYP1B1
protein-containing complex 2 CDKN2A, WARS1
intracellular membrane-bounded organelle 5 ATP2B1, CTSH, CYP1A2, CYP1B1, CYP3A4
Microsome membrane 3 CYP1A2, CYP1B1, CYP3A4
Secreted 7 AFP, BCHE, CCK, GAST, GH1, HTRA1, SST
extracellular region 7 BCHE, CCK, CTSH, GAST, GH1, HTRA1, SST
mitochondrial outer membrane 1 PGR
mitochondrial matrix 1 CDKN2A
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
nucleolus 1 CDKN2A
GABA-ergic synapse 1 SST
collagen-containing extracellular matrix 2 CTSH, HTRA1
lateral plasma membrane 1 ATP2B1
chromatin 2 PGR, STAT6
cell projection 1 ATP2B1
cytoplasmic ribonucleoprotein granule 1 CTSH
Nucleus, nucleolus 1 CDKN2A
Cytoplasmic vesicle, secretory vesicle, acrosome 1 OSBP2
blood microparticle 1 BCHE
Basolateral cell membrane 1 ATP2B1
endosome lumen 1 GH1
Nucleus, nucleoplasm 1 CDKN2A
Presynaptic cell membrane 1 ATP2B1
ficolin-1-rich granule lumen 1 CTSH
secretory granule lumen 1 CTSH
endoplasmic reticulum lumen 2 AFP, BCHE
tertiary granule lumen 1 CTSH
immunological synapse 1 ATP2B1
neuronal dense core vesicle 1 SST
perinuclear endoplasmic reticulum 1 OSBP2
nuclear envelope lumen 1 BCHE
apical dendrite 1 OSBP2
alveolar lamellar body 1 CTSH
multivesicular body lumen 1 CTSH
growth hormone receptor complex 1 GH1
[Isoform 4]: Mitochondrion outer membrane 1 PGR
photoreceptor ribbon synapse 1 ATP2B1
senescence-associated heterochromatin focus 1 CDKN2A
[Isoform smARF]: Mitochondrion 1 CDKN2A


文献列表

  • Gerard H M Huysmans, Sheena E Radford, David J Brockwell, Stephen A Baldwin. The N-terminal helix is a post-assembly clamp in the bacterial outer membrane protein PagP. Journal of molecular biology. 2007 Oct; 373(3):529-40. doi: 10.1016/j.jmb.2007.07.072. [PMID: 17868697]