Benz[c]acridine (BioDeep_00000003032)

   


代谢物信息卡片


12-Azabenz[a]anthracene

化学式: C17H11N (229.0891)
中文名称: 苯并[c] ac啶, 苯并[c]吖啶
谱图信息: 最多检出来源 Viridiplantae(plant) 83.33%

分子结构信息

SMILES: C1=CC=C2C(=C1)C=CC3=CC4=CC=CC=C4N=C32
InChI: InChI=1S/C17H11N/c1-3-7-15-12(5-1)9-10-14-11-13-6-2-4-8-16(13)18-17(14)15/h1-11H

描述信息

CONFIDENCE standard compound; INTERNAL_ID 8306
CONFIDENCE standard compound; INTERNAL_ID 8119

同义名列表

5 个代谢物同义名

Benz[c]acridine; BENZ(C)ACRIDINE; 12-Azabenz[a]anthracene; Benz[c]acridine; Benz[c]acridine



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 AHR, ALB, CYP1A1, POU5F1, PRL
Peripheral membrane protein 1 CYP1A1
Endosome membrane 1 ATP8A2
Endoplasmic reticulum membrane 2 CYP1A1, SLC27A5
Nucleus 5 ACR, AHR, ALB, POU5F1, PRL
cytosol 4 ABR, AHR, ALB, POU5F1
centrosome 1 ALB
nucleoplasm 4 AHR, ATP8A2, POU5F1, PRL
RNA polymerase II transcription regulator complex 1 PRL
Cell membrane 3 ATP8A2, LTK, SLC27A5
Cell projection, axon 1 ABR
Multi-pass membrane protein 2 ATP8A2, SLC27A5
Golgi apparatus membrane 1 ATP8A2
Synapse 1 ABR
glutamatergic synapse 1 ABR
Golgi apparatus 2 ALB, ATP8A2
Golgi membrane 1 ATP8A2
mitochondrial inner membrane 1 CYP1A1
plasma membrane 3 ATP8A2, LTK, SLC27A5
Membrane 3 ABR, ATP8A2, LTK
axon 1 ABR
extracellular exosome 2 ALB, CFH
endoplasmic reticulum 2 ALB, SLC27A5
extracellular space 3 ALB, CFH, PRL
Schaffer collateral - CA1 synapse 1 ABR
mitochondrion 2 CYP1A1, POU5F1
protein-containing complex 4 ACR, AHR, ALB, SLC27A5
intracellular membrane-bounded organelle 1 CYP1A1
Microsome membrane 1 CYP1A1
Single-pass type I membrane protein 1 LTK
Secreted 3 ALB, CFH, PRL
extracellular region 4 ACR, ALB, CFH, PRL
anchoring junction 1 ALB
transcription regulator complex 2 AHR, POU5F1
dendritic spine 1 ABR
Golgi-associated vesicle 1 ACR
Mitochondrion inner membrane 1 CYP1A1
Cell projection, dendritic spine 1 ABR
receptor complex 1 LTK
ciliary basal body 1 ALB
chromatin 3 AHR, POU5F1, PRL
cell projection 1 ATP8A2
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 2 ALB, CFH
Endomembrane system 1 ATP8A2
endosome lumen 1 PRL
aryl hydrocarbon receptor complex 1 AHR
basal plasma membrane 1 SLC27A5
Microsome 1 SLC27A5
endoplasmic reticulum lumen 1 ALB
platelet alpha granule lumen 1 ALB
Photoreceptor inner segment membrane 1 ATP8A2
serine-type endopeptidase complex 1 CFH
photoreceptor outer segment membrane 1 ATP8A2
phospholipid-translocating ATPase complex 1 ATP8A2
symbiont cell surface 1 CFH
acrosomal matrix 1 ACR
nuclear aryl hydrocarbon receptor complex 1 AHR
cytosolic aryl hydrocarbon receptor complex 1 AHR
ciliary transition fiber 1 ALB


文献列表

  • Arkadiusz Szterk, Marek Roszko, Adam Cybulski. Determination of azaarenes in oils using the LC-APCI-MS/MS technique: new environmental toxicant in food oils. Journal of separation science. 2012 Nov; 35(21):2858-65. doi: 10.1002/jssc.201200570. [PMID: 23047737]
  • R Vecera, B Klejdus, P Kosina, J Orolin, M Stiborová, S Smrcek, J Vicar, Z Dvorák, J Ulrichová, V Kubán, P Anzenbacher, V Simánek. Disposition of sanguinarine in the rat. Xenobiotica; the fate of foreign compounds in biological systems. 2007 May; 37(5):549-58. doi: 10.1080/00498250701230542. [PMID: 17523056]
  • Jitka Psotová, Borivoj Klejdus, Rostislav Vecera, Pavel Kosina, Vlastimil Kubán, Jaroslav Vicar, Vilím Simánek, Jitka Ulrichová. A liquid chromatographic-mass spectrometric evidence of dihydrosanguinarine as a first metabolite of sanguinarine transformation in rat. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2006 Jan; 830(1):165-72. doi: 10.1016/j.jchromb.2005.10.030. [PMID: 16280262]
  • A W Wood, R L Chang, W Levin, D E Ryan, P E Thomas, R E Lehr, S Kumar, M Schaefer-Ridder, U Engelhardt, H Yagi, D M Jerina, A H Conney. Mutagenicity of diol-epoxides and tetrahydroepoxides of benz(a)acridine and benz(c)acridine in bacteria and in mammalian cells. Cancer research. 1983 Apr; 43(4):1656-62. doi: . [PMID: 6339041]