dCDP (BioDeep_00000002934)
Secondary id: BioDeep_00000400218, BioDeep_00001868784
natural product human metabolite PANOMIX_OTCML-2023 Endogenous BioNovoGene_Lab2019 Volatile Flavor Compounds
代谢物信息卡片
化学式: C9H15N3O10P2 (387.023267)
中文名称: 2'-脱氧胞苷-5'-二磷酸, 2'-脱氧胞苷5'-二磷酸
谱图信息:
最多检出来源 Homo sapiens(blood) 0.18%
分子结构信息
SMILES: C1C(C(OC1N2C=CC(=NC2=O)N)COP(=O)(O)OP(=O)(O)O)O
InChI: InChI=1S/C9H15N3O10P2/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(21-8)4-20-24(18,
描述信息
dCDP is a substrate for Uridine-cytidine kinase 1, Nucleoside diphosphate kinase (mitochondrial), Nucleoside diphosphate kinase homolog 5, Ribonucleoside-diphosphate reductase large subunit, Nucleoside diphosphate kinase A, Nucleoside diphosphate kinase 7, Ribonucleoside-diphosphate reductase M2 chain, Nucleoside diphosphate kinase B, Nucleoside diphosphate kinase 3, Nucleoside diphosphate kinase 6 and UMP-CMP kinase. [HMDB]. dCDP is found in many foods, some of which are oil palm, sweet bay, garden onion (variety), and italian sweet red pepper.
dCDP is a substrate for Uridine-cytidine kinase 1, Nucleoside diphosphate kinase (mitochondrial), Nucleoside diphosphate kinase homolog 5, Ribonucleoside-diphosphate reductase large subunit, Nucleoside diphosphate kinase A, Nucleoside diphosphate kinase 7, Ribonucleoside-diphosphate reductase M2 chain, Nucleoside diphosphate kinase B, Nucleoside diphosphate kinase 3, Nucleoside diphosphate kinase 6 and UMP-CMP kinase.
Acquisition and generation of the data is financially supported in part by CREST/JST.
同义名列表
27 个代谢物同义名
[({[(2R,3S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid; 4-Amino-1-[2-deoxy-5-O-[hydroxy(phosphonooxy)phosphinyl]-beta-delta-erythro-pentofuranosyl]-2(1H)-pyrimidinone; 4-Amino-1-[2-deoxy-5-O-[hydroxy(phosphonooxy)phosphinyl]-beta-D-erythro-pentofuranosyl]-2(1H)-pyrimidinone; D-1beta-Ribofuranosylcytosine diphosphoric acid; delta-1beta-Ribofuranosylcytosine diphosphate; D-1Β-ribofuranosylcytosine diphosphoric acid; D-1b-Ribofuranosylcytosine diphosphoric acid; 2-Deoxycytidine-5-diphosphate sodium salt; D-1beta-Ribofuranosylcytosine diphosphate; D-1b-Ribofuranosylcytosine diphosphate; D-1Β-ribofuranosylcytosine diphosphate; 2-Deoxycytidine 5-diphosphoric acid; 2-Deoxycytidine diphosphate (dCDP); 2-Deoxycytidine diphosphoric acid; 2-Deoxy-cytidine 5-pyrophosphate; Deoxycytidine diphosphoric acid; 2-Deoxy-cytidine pyrophosphate; 2-Deoxycytidine-5-diphosphate; 2-Deoxycytidine 5-diphosphate; 2-Deoxycytidine diphosphate; Deoxycytidine 5-diphosphate; Deoxycytidine diphosphate; Deoxy-CDP; dCDP; Deoxycytidine-diphosphate; dCDP; 2'-Deoxycytidine 5'-diphosphate
数据库引用编号
31 个数据库交叉引用编号
- ChEBI: CHEBI:28846
- KEGG: C00705
- PubChem: 150855
- PubChem: 623
- HMDB: HMDB0001245
- Metlin: METLIN3514
- Wikipedia: Deoxycytidine_diphosphate
- MetaCyc: DCDP
- foodb: FDB022510
- chemspider: 132961
- CAS: 800-73-7
- MoNA: PS014501
- MoNA: PR100523
- MoNA: PR100087
- MoNA: PS014506
- MoNA: PS014502
- MoNA: PS014511
- MoNA: PR100088
- MoNA: PS014504
- MoNA: PS014507
- MoNA: PS014508
- MoNA: PS014505
- MoNA: PS014503
- PMhub: MS000007238
- PubChem: 3972
- PDB-CCD: YYY
- 3DMET: B01317
- NIKKAJI: J247.701G
- RefMet: dCDP
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-362
- KNApSAcK: 28846
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
29 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(2)
- pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dCTP ⟶ ammonia + dUTP
- pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dCTP ⟶ ammonia + dUTP
Plant Reactome(0)
INOH(3)
- Pyrimidine Nucleotides and Nucleosides metabolism ( Pyrimidine Nucleotides and Nucleosides metabolism ):
Deoxy-cytidine + H2O ⟶ Deoxy-uridine + NH3
- ATP + dCDP = ADP + dCTP ( Pyrimidine Nucleotides and Nucleosides metabolism ):
ATP + dCDP ⟶ ADP + dCTP
- ATP + dCMP = ADP + dCDP ( Pyrimidine Nucleotides and Nucleosides metabolism ):
ADP + dCDP ⟶ ATP + dCMP
PlantCyc(0)
PathBank(22)
- Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- beta-Ureidopropionase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- UMP Synthase Deficiency (Orotic Aciduria):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- Dihydropyrimidinase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- Pyrimidine Metabolism:
Hydrogen Ion + N-carbamoyl-L-aspartate ⟶ 4,5-Dihydroorotic acid + Water
- Pyrimidine Metabolism:
Hydrogen Ion + N-carbamoyl-L-aspartate ⟶ 4,5-Dihydroorotic acid + Water
- Pyrimidine Deoxyribonucleosides Salvage:
Deoxycytidine + Hydrogen Ion + Water ⟶ Ammonium + Deoxyuridine
- Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- beta-Ureidopropionase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- Dihydropyrimidinase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- UMP Synthase Deficiency (Orotic Aciduria):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- beta-Ureidopropionase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- Dihydropyrimidinase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- UMP Synthase Deficiency (Orotic Aciduria):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine
- Pyrimidine Metabolism:
Hydrogen Ion + N-carbamoyl-L-aspartate ⟶ 4,5-Dihydroorotic acid + Water
PharmGKB(0)
2 个相关的物种来源信息
- 9606 - Homo sapiens: -
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- J Taljanidisz, M Sasvari-Szekely, T Spasokutotskaja, F Antoni, M Staub. Reversible permeabilization of lymphocytes destroys the incorporation of deoxythymidine but not of deoxycytidine.
Biochimica et biophysica acta.
1986 Mar; 885(3):266-71. doi:
10.1016/0167-4889(86)90241-7
. [PMID: 3947681] - D R Narine, S Bacchetti, W W Chan. An assay for ribonucleotide reductase based on ion-exchange chromatography of the reaction product.
Analytical biochemistry.
1985 Mar; 145(2):331-8. doi:
10.1016/0003-2697(85)90370-7
. [PMID: 2990252] - W C SCHNEIDER. INTRACELLULAR DISTRIBUTION OF ENZYMES. XIII. ENZYMATIC SYNTHESIS OF DEOXYCYTIDINE DIPHOSPHATE CHOLINE AND LECITHIN IN RAT LIVER.
The Journal of biological chemistry.
1963 Nov; 238(?):3572-8. doi:
"
. [PMID: 14109188]