Kaempferol 7-glucoside (BioDeep_00000228370)

 

Secondary id: BioDeep_00000396394

human metabolite PANOMIX_OTCML-2023 natural product


代谢物信息卡片


3,5-dihydroxy-2-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-4-one

化学式: C21H20O11 (448.1006)
中文名称: 山奈酚-7-O-葡萄糖苷, 山奈酚-4’’-葡萄糖苷, 山奈酚-4'-O-Β-D-葡萄糖苷
谱图信息: 最多检出来源 Homo sapiens(otcml) 1.08%

分子结构信息

SMILES: c(c3)(ccc(OC(O4)C(O)C(O)C(O)C4CO)c3)C(=C2O)Oc(c1)c(C2=O)c(cc(O)1)O
InChI: InChI=1S/C21H20O11/c22-7-13-15(25)17(27)19(29)21(32-13)30-10-5-11(24)14-12(6-10)31-20(18(28)16(14)26)8-1-3-9(23)4-2-8/h1-6,13,15,17,19,21-25,27-29H,7H2/t13-,15-,17+,19-,21-/m1/s1

描述信息

Kaempferol 7-glucoside is a member of the class of compounds known as flavonoid-7-o-glycosides. Flavonoid-7-o-glycosides are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position. Kaempferol 7-glucoside is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Kaempferol 7-glucoside can be found in a number of food items such as flaxseed, ginkgo nuts, white cabbage, and saffron, which makes kaempferol 7-glucoside a potential biomarker for the consumption of these food products.

同义名列表

9 个代谢物同义名

3,5-dihydroxy-2-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-4-one; 3,5-dihydroxy-2-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one; 3,5,7,4-Tetrahydroxyflavone 4-glucoside; kaempferol 7-O-β-D-glucopyranoside; Kaempferol 7-O-b-D-glucopyranoside; kaempferol 7-O-beta-glucoside; kaempferol 7-O-glucoside; Kaempferol 7-glucoside; Kaempferol 4-glucoside



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

311 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Gulsim Zhumashova, Wirginia Kukula-Koch, Wojciech Koch, Tomasz Baj, Galiya Sayakova, Alma Shukirbekova, Kazimierz Głowniak, Zuriyadda Sakipova. Phytochemical and Antioxidant Studies on a Rare Rheum cordatum Losinsk. Species from Kazakhstan. Oxidative medicine and cellular longevity. 2019; 2019(?):5465463. doi: 10.1155/2019/5465463. [PMID: 31827680]
  • Seung-Bin Lee, Ji-Sun Shin, Hee-Soo Han, Hwi-Ho Lee, Jong Cheol Park, Kyung-Tae Lee. Kaempferol 7-O-β-D-glucoside isolated from the leaves of Cudrania tricuspidata inhibits LPS-induced expression of pro-inflammatory mediators through inactivation of NF-κB, AP-1, and JAK-STAT in RAW 264.7 macrophages. Chemico-biological interactions. 2018 Mar; 284(?):101-111. doi: 10.1016/j.cbi.2018.02.022. [PMID: 29470957]
  • Jiwon Baek, Dahae Lee, Tae Kyoung Lee, Ji Hoon Song, Ju Sung Lee, Seong Lee, Sang-Woo Yoo, Ki Sung Kang, Eunjung Moon, Sanghyun Lee, Ki Hyun Kim. (-)-9'-O-(α-l-Rhamnopyranosyl)lyoniresinol from Lespedeza cuneata suppresses ovarian cancer cell proliferation through induction of apoptosis. Bioorganic & medicinal chemistry letters. 2018 01; 28(2):122-128. doi: 10.1016/j.bmcl.2017.11.045. [PMID: 29223588]
  • Mingzhi Zhu, Ting Liu, Chunyun Zhang, Mingquan Guo. Flavonoids of Lotus (Nelumbo nucifera) Seed Embryos and Their Antioxidant Potential. Journal of food science. 2017 Aug; 82(8):1834-1841. doi: 10.1111/1750-3841.13784. [PMID: 28631810]
  • Kyeong Wan Woo, Eunjung Moon, So Young Park, Sun Yeou Kim, Kang Ro Lee. Flavonoid glycosides from the leaves of Allium victorialis var. platyphyllum and their anti-neuroinflammatory effects. Bioorganic & medicinal chemistry letters. 2012 Dec; 22(24):7465-70. doi: 10.1016/j.bmcl.2012.10.043. [PMID: 23149227]
  • Jiandong Yu, Zhong Dai, Ruichao Lin. [Chemical constituents of Viola tianshanica]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2009 Nov; 34(22):2916-7. doi: ". [PMID: 20209959]
  • Young Jae Lee, Sungun Kim, Seung Jae Lee, Inhye Ham, Wan Kyunn Whang. Antioxidant activities of new flavonoids from Cudrania tricuspidata root bark. Archives of pharmacal research. 2009 Feb; 32(2):195-200. doi: 10.1007/s12272-009-1135-z. [PMID: 19280148]
  • Daisuke Kami, Jun Kasuga, Keita Arakawa, Seizo Fujikawa. Improved cryopreservation by diluted vitrification solution with supercooling-facilitating flavonol glycoside. Cryobiology. 2008 Dec; 57(3):242-5. doi: 10.1016/j.cryobiol.2008.09.003. [PMID: 18824164]
  • Jun Kasuga, Yasuyuki Hashidoko, Atsushi Nishioka, Megumi Yoshiba, Keita Arakawa, Seizo Fujikawa. Deep supercooling xylem parenchyma cells of katsura tree (Cercidiphyllum japonicum) contain flavonol glycosides exhibiting high anti-ice nucleation activity. Plant, cell & environment. 2008 Sep; 31(9):1335-48. doi: 10.1111/j.1365-3040.2008.01835.x. [PMID: 18518920]
  • Wen Xu, Jianwen Liu, Changlong Li, He-Zhen Wu, Yan-Wen Liu. Kaempferol-7-O-beta-D-glucoside (KG) isolated from Smilax china L. rhizome induces G2/M phase arrest and apoptosis on HeLa cells in a p53-independent manner. Cancer letters. 2008 Jun; 264(2):229-40. doi: 10.1016/j.canlet.2008.01.044. [PMID: 18343026]
  • Yuan-Li Li, Guo-Ping Gan, Hui-Zhan Zhang, He-Zhen Wu, Chang-Long Li, Yong-Ping Huang, Yan-Wen Liu, Jian-Wen Liu. A flavonoid glycoside isolated from Smilax china L. rhizome in vitro anticancer effects on human cancer cell lines. Journal of ethnopharmacology. 2007 Aug; 113(1):115-24. doi: 10.1016/j.jep.2007.05.016. [PMID: 17606345]
  • Prasoon Gupta, Akanksha, Kiran Babu Siripurapu, Ausaf Ahmad, Gautam Palit, Ashish Arora, Rakesh Maurya. Anti-stress constituents of Evolvulus alsinoides: an ayurvedic crude drug. Chemical & pharmaceutical bulletin. 2007 May; 55(5):771-5. doi: 10.1248/cpb.55.771. [PMID: 17473466]
  • Jing Xu, Xian Li, Peng Zhang, Zhan-Lin Li, Yi Wang. Antiinflammatory constituents from the roots of Smilax bockii warb. Archives of pharmacal research. 2005 Apr; 28(4):395-9. doi: 10.1007/bf02977667. [PMID: 15918511]