4-OXO-4-(PYRIDIN-3-YL)BUTANOIC ACID (BioDeep_00001868797)

Main id: BioDeep_00000001243

 


代谢物信息卡片


4-OXO-4-(PYRIDIN-3-YL)BUTANOIC ACID

化学式: C9H9NO3 (179.0582)
中文名称: 4-氧代-4-(吡啶-3-基)丁酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CN=C1)C(=O)CCC(=O)O
InChI: InChI=1S/C9H9NO3/c11-8(3-4-9(12)13)7-2-1-5-10-6-7/h1-2,5-6H,3-4H2,(H,12,13)



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 CD36, CYP2A13, CYP2A6, CYP2B6, DYNC1H1, HBS1L
Peripheral membrane protein 4 CYP1B1, CYP2B6, GBA1, HSD17B6
Endoplasmic reticulum membrane 6 CD59, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2B6
cytosol 2 DYNC1H1, HBS1L
phagocytic vesicle 1 CD36
trans-Golgi network 1 GBA1
centrosome 1 DYNC1H1
Cell membrane 2 CD36, CD59
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 1 CD36
cell cortex 1 DYNC1H1
cell surface 2 CD36, CD59
Golgi apparatus 2 CD36, GBA1
Golgi membrane 1 CD59
lysosomal membrane 1 GBA1
Lysosome 1 GBA1
plasma membrane 2 CD36, CD59
Membrane 6 CD36, CD59, CYP1B1, CYP2A6, DYNC1H1, HBS1L
apical plasma membrane 1 CD36
caveola 1 CD36
extracellular exosome 4 CD59, DYNC1H1, GBA1, HBS1L
Lysosome membrane 1 GBA1
Lumenal side 2 GBA1, HSD17B6
endoplasmic reticulum 2 GBA1, HSD17B6
extracellular space 2 CD36, CD59
lysosomal lumen 1 GBA1
mitochondrion 1 CYP1B1
intracellular membrane-bounded organelle 6 CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2B6, HSD17B6
Microsome membrane 4 CYP1A2, CYP1B1, CYP2B6, HSD17B6
filopodium 1 DYNC1H1
extracellular region 1 DYNC1H1
external side of plasma membrane 2 CD36, CD59
axon cytoplasm 1 DYNC1H1
vesicle 1 CD59
Apical cell membrane 1 CD36
Membrane raft 1 CD36
Cytoplasm, cytoskeleton 1 DYNC1H1
focal adhesion 1 CD59
microtubule 1 DYNC1H1
collagen trimer 1 CD36
receptor complex 1 CD36
cell periphery 1 CD36
brush border membrane 1 CD36
Lipid-anchor, GPI-anchor 1 CD59
specific granule membrane 2 CD36, CD59
tertiary granule membrane 1 CD59
side of membrane 1 CD59
endocytic vesicle membrane 1 CD36
transport vesicle 1 CD59
azurophil granule lumen 1 DYNC1H1
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 CD59
cytoplasmic dynein complex 1 DYNC1H1
dynein complex 1 DYNC1H1
ER to Golgi transport vesicle membrane 1 CD59
[Isoform 2]: Cytoplasm 1 HBS1L
cytoplasmic microtubule 2 CYP2A6, DYNC1H1
cytosolic ribosome 1 HBS1L
platelet alpha granule membrane 1 CD36
Dom34-Hbs1 complex 1 HBS1L


文献列表

  • Irina Stepanov, Pramod Upadhyaya, Steven G Carmella, Rachel Feuer, Joni Jensen, Dorothy K Hatsukami, Stephen S Hecht. Extensive metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2008 Jul; 17(7):1764-73. doi: 10.1158/1055-9965.epi-07-2844. [PMID: 18628430]
  • Stefan Tyroller, Wolfgang Zwickenpflug, Charlotte Thalheim, Elmar Richter. Acute and subacute effects of tobacco alkaloids, tobacco-specific nitrosamines and phenethyl isothiocyanate on N'-nitrosonornicotine metabolism in rats. Toxicology. 2005 Nov; 215(3):245-53. doi: 10.1016/j.tox.2005.07.011. [PMID: 16118032]
  • Wolfgang Zwickenpflug, Stefan Tyroller, Elmar Richter. Metabolism of myosmine in Wistar rats. Drug metabolism and disposition: the biological fate of chemicals. 2005 Nov; 33(11):1648-56. doi: 10.1124/dmd.104.003087. [PMID: 16079272]
  • B G Brown, E Richter, A R Tricker, P H Ayres, D J Doolittle. The effect of a 2-h exposure to cigarette smoke on the metabolic activation of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mice. Chemico-biological interactions. 2001 Nov; 138(2):125-35. doi: 10.1016/s0009-2797(01)00265-4. [PMID: 11672696]
  • H Isaacs, J J Heffron, M Badenhorst. 'Picture frame' fibres in a carrier of the trait for malignant hyperpyrexia. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 1975 Nov; 49(46):1923-6. doi: NULL. [PMID: 795]
  • . . . . doi: . [PMID: 10027795]