Terconazole (BioDeep_00001868014)
Main id: BioDeep_00000006658
Volatile Flavor Compounds
代谢物信息卡片
化学式: C26H31Cl2N5O3 (531.1803836)
中文名称: 曲康唑
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)N1CCN(CC1)c1ccc(cc1)OC[C@H]1CO[C@](Cn2cncn2)(c2ccc(cc2Cl)Cl)O1
InChI: InChI=1S/C26H31Cl2N5O3/c1-19(2)31-9-11-32(12-10-31)21-4-6-22(7-5-21)34-14-23-15-35-26(36-23,16-33-18-29-17-30-33)24-8-3-20(27)13-25(24)28/h3-8,13,17-19,23H,9-12,14-16H2,1-2H3/t23-,26-/m0/s1
描述信息
G - Genito urinary system and sex hormones > G01 - Gynecological antiinfectives and antiseptics > G01A - Antiinfectives and antiseptics, excl. combinations with corticosteroids > G01AG - Triazole derivatives
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
同义名列表
2 个代谢物同义名
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:82980
- ChEBI: CHEBI:9451
- KEGG: C76152
- KEGG: C08080
- KEGGdrug: D00888
- PubChem: 441383
- DrugBank: DB00251
- ChEMBL: CHEMBL1306
- CAS: 172587-59-6
- CAS: 67915-31-5
- PubChem: 10280
- NIKKAJI: J290.530B
- RefMet: Terconazole
- KNApSAcK: 9451
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Shaimaa Mosallam, Maha H Ragaie, Noha H Moftah, Ahmed Hassen Elshafeey, Aly Ahmed Abdelbary. Use of Novasomes as a Vesicular Carrier for Improving the Topical Delivery of Terconazole: In Vitro Characterization, In Vivo Assessment and Exploratory Clinical Experimentation.
International journal of nanomedicine.
2021; 16(?):119-132. doi:
10.2147/ijn.s287383. [PMID: 33447031] - Maha M Abou El-Alamin, Maha A Sultan, Mostafa A Atia, Hassan Y Aboul-Enein. Novel Application of Pentabromobenzyl Column for Simultaneous Determination of Eight Antifungal Drugs Using High-performance Liquid Chromatography.
Combinatorial chemistry & high throughput screening.
2020; 23(10):991-1001. doi:
10.2174/1386207323666200220114818. [PMID: 32077818] - Chandran Sivasankar, Subramanian Gayathri, James Prabhanand Bhaskar, Venkat Krishnan, Shunmugiah Karutha Pandian. Evaluation of selected Indian medicinal plants for antagonistic potential against Malassezia spp. and the synergistic effect of embelin in combination with ketoconazole.
Microbial pathogenesis.
2017 Sep; 110(?):66-72. doi:
10.1016/j.micpath.2017.06.026. [PMID: 28645774] - Ellen L Berg, Mark A Polokoff, Alison O'Mahony, Dat Nguyen, Xitong Li. Elucidating mechanisms of toxicity using phenotypic data from primary human cell systems--a chemical biology approach for thrombosis-related side effects.
International journal of molecular sciences.
2015 Jan; 16(1):1008-29. doi:
10.3390/ijms16011008. [PMID: 25569083] - Thomas Hartwig, Claudia Corvalan, Norman B Best, Joshua S Budka, Jia-Ying Zhu, Sunghwa Choe, Burkhard Schulz. Propiconazole is a specific and accessible brassinosteroid (BR) biosynthesis inhibitor for Arabidopsis and maize.
PloS one.
2012; 7(5):e36625. doi:
10.1371/journal.pone.0036625. [PMID: 22590578] - Yasuto Kido, Pär Matsson, Kathleen M Giacomini. Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.
Journal of medicinal chemistry.
2011 Jul; 54(13):4548-58. doi:
10.1021/jm2001629. [PMID: 21599003] - Tomasz Grabowski, Anna Swierczewska, Beata Borucka, Renata Sawicka, Małgorzata Sasinowska-Motyl, Stanisław Witold Gumułka. Chromatographic/mass spectrometric method for the estimation of itraconazole and its metabolite in human plasma. Application to a bioequivalence study.
Arzneimittel-Forschung.
2009; 59(8):422-8. doi:
10.1055/s-0031-1296418. [PMID: 19813466] - D M Isaacson, E L Tolman, A J Tobia, M E Rosenthale, J L McGuire, H Vanden Bossche, P A Janssen. Selective inhibition of 14 alpha-desmethyl sterol synthesis in Candida albicans by terconazole, a new triazole antimycotic.
The Journal of antimicrobial chemotherapy.
1988 Mar; 21(3):333-43. doi:
10.1093/jac/21.3.333. [PMID: 3129389] - B K Kennedy, N Friedmann. Terconazole cream and suppositories: plasma terconazole following vaginal administration.
Gynakologische Rundschau.
1985; 25 Suppl 1(?):26-32. doi:
10.1159/000269985. [PMID: 4007621] - L CAROLINE, C L TASCHDJIAN, P J KOZINN, A L SCHADE. REVERSAL OF SERUM FUNGISTASIS BY ADDITION OF IRON.
The Journal of investigative dermatology.
1964 Jun; 42(?):415-9. doi:
10.1038/jid.1964.90. [PMID: 14172197] - H J HEITE, A BUCK, C LEHMANN. [QUANTITATIVE STUDIES ON THE FUNGISTATIC ACTIVITY OF HUMAN SERUM TOWARDS CANDIDA ALBICANS].
Dermatologica.
1964; 128(?):350-71. doi:
NULL. [PMID: 14162992] - G L BAUM, D ARTIS. Fungistatic effects of cell free human serum.
The American journal of the medical sciences.
1961 Dec; 242(?):761-70. doi:
10.1097/00000441-196112000-00015. [PMID: 13865903] - D JANKE. [A methodical improvement of the demonstration of serum fungistasis].
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete.
1959 Sep; 10(?):422. doi:
NULL. [PMID: 14406687] - F J ROTH, C C BOYD, S SAGAMI, H BLANK. An evaluation of the fungistatic activity of serum.
The Journal of investigative dermatology.
1959 May; 32(5):549-56. doi:
10.1038/jid.1959.92. [PMID: 13654841] - J KUC, A J ULLSTRUP, F W QUACKENBUSH. Production of fungistatic substances by plant tissue after inoculation.
Science (New York, N.Y.).
1955 Dec; 122(3181):1186-7. doi:
10.1126/science.122.3181.1186-a. [PMID: 13274078] - B C HEIBERG, G B RAMSEY. Fungistatic action of diphenyl on some fruit and vegetable pathogens.
Phytopathology.
1946 Oct; 36(10):887-91. doi:
". [PMID: 21001022]