Picosulfuric acid (BioDeep_00000182421)

   

human metabolite blood metabolite


代谢物信息卡片


{4-[(pyridin-2-yl)[4-(sulphooxy)phenyl]methyl]phenyl}oxidanesulphonic acid

化学式: C18H15NO8S2 (437.0239)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 100%

分子结构信息

SMILES: C1=CC=NC(=C1)C(C2=CC=C(C=C2)OS(=O)(=O)O)C3=CC=C(C=C3)OS(=O)(=O)O
InChI: InChI=1S/C18H15NO8S2/c20-28(21,22)26-15-8-4-13(5-9-15)18(17-3-1-2-12-19-17)14-6-10-16(11-7-14)27-29(23,24)25/h1-12,18H,(H,20,21,22)(H,23,24,25)

描述信息

同义名列表

9 个代谢物同义名

{4-[(pyridin-2-yl)[4-(sulphooxy)phenyl]methyl]phenyl}oxidanesulphonic acid; {4-[(pyridin-2-yl)[4-(sulfooxy)phenyl]methyl]phenyl}oxidanesulfonic acid; {4-[(pyridin-2-yl)[4-(sulphooxy)phenyl]methyl]phenyl}oxidanesulphonate; (4-{pyridin-2-yl[4-(sulfooxy)phenyl]methyl}phenyl)oxidanesulfonic acid; {4-[(pyridin-2-yl)[4-(sulfooxy)phenyl]methyl]phenyl}oxidanesulfonate; Picosulphuric acid; Picosulfuric acid; Picosulphate; Picosulfate



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Christian Friedrich, Erika Richter, Dirk Trommeshauser, Sandra de Kruif, Thijs van Iersel, Ken Mandel, Ulrika Gessner. Absence of excretion of the active moiety of bisacodyl and sodium picosulfate into human breast milk: an open-label, parallel-group, multiple-dose study in healthy lactating women. Drug metabolism and pharmacokinetics. 2011; 26(5):458-64. doi: 10.2133/dmpk.dmpk-11-rg-007. [PMID: 21697613]
  • Souleymane Méité, Calixte Bahi, Dodéhé Yéo, Jacques Y Datté, Joseph A Djaman, David J N'guessan. Laxative activities of Mareya micrantha (Benth.) Müll. Arg. (Euphorbiaceae) leaf aqueous extract in rats. BMC complementary and alternative medicine. 2010 Feb; 10(?):7. doi: 10.1186/1472-6882-10-7. [PMID: 20158903]
  • Koichi Nagata, Tomohiko Okawa, Akihiro Honma, Shungo Endo, Shin-ei Kudo, Hiroyuki Yoshida. Full-laxative versus minimum-laxative fecal-tagging CT colonography using 64-detector row CT: prospective blinded comparison of diagnostic performance, tagging quality, and patient acceptance. Academic radiology. 2009 Jul; 16(7):780-9. doi: 10.1016/j.acra.2008.12.027. [PMID: 19375954]
  • Yoshihiko Hirotani, Kyoko Mikajiri, Kenji Ikeda, Michiaki Myotoku, Nobuo Kurokawa. Changes of intestinal mucosal and plasma PYY in a diarrhea model rat and influence of loperamide as the treatment agent for diarrhea. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2008 Sep; 128(9):1311-6. doi: 10.1248/yakushi.128.1311. [PMID: 18758145]
  • Paulo Miki, Carlos Renato dos Reis Lemos, Pedro Popoutchi, Ricardo Luiz dos Santos Garcia, José Joaquim Ribeiro da Rocha, Omar Feres. Comparison of colon-cleansing methods in preparation for colonoscopy--comparative efficacy of solutions of mannitol, sodium picosulfate and monobasic and dibasic sodium phosphates. Acta cirurgica brasileira. 2008; 23 Suppl 1(?):108-11; discussion 111. doi: 10.1590/s0102-86502008000700018. [PMID: 18516457]
  • Ju-Xiu He, Emi Goto, Teruaki Akao, Tadato Tani. Interaction between Shaoyao-Gancao-Tang and a laxative with respect to alteration of paeoniflorin metabolism by intestinal bacteria in rats. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2007 Aug; 14(7-8):452-9. doi: 10.1016/j.phymed.2006.09.014. [PMID: 17097282]
  • Emi Goto, Ju-Xiu He, Teruaki Akao, Tadato Tani. Bioavailability of glycyrrhizin from Shaoyao-Gancao-Tang in laxative-treated rats. The Journal of pharmacy and pharmacology. 2005 Oct; 57(10):1359-63. doi: 10.1211/jpp.57.10.0016. [PMID: 16259766]
  • Jochen Beyer, Frank T Peters, Hans H Maurer. Screening procedure for detection of stimulant laxatives and/or their metabolites in human urine using gas chromatography-mass spectrometry after enzymatic cleavage of conjugates and extractive methylation. Therapeutic drug monitoring. 2005 Apr; 27(2):151-7. doi: 10.1097/01.ftd.0000150878.36296.04. [PMID: 15795644]
  • Monique P Curran, Greg L Plosker. Oral sodium phosphate solution: a review of its use as a colorectal cleanser. Drugs. 2004; 64(15):1697-714. doi: 10.2165/00003495-200464150-00009. [PMID: 15257632]
  • H Ito, T Kiso, H Yuki, Y Naitoh, K Miyata, K Iwaoka, T Yamaguchi. Investigation of the effects of YM-31636, a novel 5-HT3 receptor agonist, on defecation in normal and constipated ferrets. European journal of pharmacology. 2001 Jul; 424(2):151-7. doi: 10.1016/s0014-2999(01)01147-5. [PMID: 11476761]
  • D H Kim, S H Hyun, S B Shim, K Kobashi. The role of intestinal bacteria in the transformation of sodium picosulfate. Japanese journal of pharmacology. 1992 May; 59(1):1-5. doi: 10.1254/jjp.59.1. [PMID: 1507649]